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List of works by Luc Leybaert

(18)F-fluoromethylcholine (FCho), (18)F-fluoroethyltyrosine (FET), and (18)F-fluorodeoxyglucose (FDG) for the discrimination between high-grade glioma and radiation necrosis in rats: a PET study.

scientific article published on 15 August 2014

A Rwandan altitude blood gas, acid-base and hemoglobin study

scientific article published on 01 July 2005

A Simple Method for High Temporal Resolution Calcium Imaging with Dual Excitation Dyes ⬇️

scientific article published on October 1, 1998

A new angle on blood-CNS interfaces: a role for connexins?

scientific article published on 12 March 2014

A novel design for steerable instruments based on laser-cut nitinol

scientific article

A novel method for the evaluation of intestinal transit and contractility in mice using fluorescence imaging and spatiotemporal motility mapping

scientific article

A voltage-clamp study of calcium currents in neurons freshly isolated from the dorsal root ganglion of adult rats

scientific article published in September 1993

ATP-dependent astrocyte-endothelial calcium signaling following mechanical damage to a single astrocyte in astrocyte-endothelial co-cultures.

scientific article published on April 2000

Absence of haemodynamic refractory effects in patients with migraine without aura: an interictal fMRI study

scientific article published on 3 August 2011

Alpha-helical destabilization of the Bcl-2-BH4-domain peptide abolishes its ability to inhibit the IP3 receptor

scientific article

Apoptotic granulosa cells have moderately increased intracellular free calcium during phosphatidylserine exposure and a normal resting calcium level during DNA fragmentation

scientific article published in October 1998

Astrocyte-endothelial cell calcium signals conveyed by two signalling pathways

scientific article

Astrocytic Connexin43 Channels as Candidate Targets in Epilepsy Treatment

scientific article published on 20 November 2020

Bcl-2 binds to and inhibits ryanodine receptors

scientific article published on 24 April 2014

Ca(2+) regulation of connexin 43 hemichannels in C6 glioma and glial cells

scientific article published on 4 August 2009

Calcium and connexin-based intercellular communication, a deadly catch?

scientific article published on 31 May 2011

Calcium dynamics: spatio-temporal organization from the subcellular to the organ level.

scientific article published on January 2007

Calcium signal communication between glial and vascular brain cells.

scientific article published in June 2004

Calcium signal communication in the central nervous system.

scientific article published on February 2004

Changes of intracellular free calcium during intracytoplasmic sperm injection

scientific article published in February 1996

Changes of intracellular free calcium following mechanical injury in a spinal cord slice preparation

scientific article published in December 1996

Characterization of spontaneous cell death in monolayer cultures of primary hepatocytes.

scientific article

Chemically, mechanically, and hyperosmolarity-induced calcium responses of rat cortical capillary endothelial cells in culture.

scientific article published on June 1999

Connexin 43 hemichannels contribute to cytoplasmic Ca2+ oscillations by providing a bimodal Ca2+-dependent Ca2+ entry pathway

scientific article

Connexin 43 hemichannels contribute to the propagation of apoptotic cell death in a rat C6 glioma cell model.

scientific article published on 26 September 2008

Connexin 43 impacts on mitochondrial potassium uptake.

scientific article published on 6 June 2013

Connexin 43 is an emerging therapeutic target in ischemia/reperfusion injury, cardioprotection and neuroprotection

scientific article

Connexin and pannexin (hemi)channels in the liver.

scientific article published on 10 January 2014

Connexin and pannexin hemichannels in brain glial cells: properties, pharmacology, and roles ⬇️

scientific article published on July 17, 2013

Connexin and pannexin signaling pathways, an architectural blueprint for CNS physiology and pathology?

scientific article

Connexin channels provide a target to manipulate brain endothelial calcium dynamics and blood-brain barrier permeability

scientific article

Connexin channels, connexin mimetic peptides and ATP release

scientific article published in July 2003

Connexin hemichannel inhibition reduces acetaminophen-induced liver injury in mice

scientific article published on 4 July 2017

Connexin hemichannels and gap junction channels are differentially influenced by lipopolysaccharide and basic fibroblast growth factor

scientific article published in November 2006

Connexin mimetic peptides inhibit Cx43 hemichannel opening triggered by voltage and intracellular Ca2+ elevation

scientific article published on 21 October 2012

Connexin targeting peptides as inhibitors of voltage- and intracellular Ca2+-triggered Cx43 hemichannel opening.

scientific article published on 02 September 2013

Connexin-related signaling in cell death: to live or let die?

scientific article published on 06 February 2009

Connexin32 hemichannels contribute to the apoptotic-to-necrotic transition during Fas-mediated hepatocyte cell death

scientific article published on 4 December 2009

Connexin43 signaling contributes to spontaneous apoptosis in cultures of primary hepatocytes

scientific article published on 14 October 2011

Connexins and their channels in inflammation

scientific article

Connexins: sensors and regulators of cell cycling.

scientific article published on 27 August 2010

Contribution of Astroglial Cx43 Hemichannels to the Modulation of Glutamatergic Currents by D-Serine in the Mouse Prefrontal Cortex.

scientific article published on 11 August 2017

Culture conditions affect Ca2+ release in artificially activated mouse and human oocytes

scientific article published on 12 January 2018

Cx43-hemichannel function and regulation in physiology and pathophysiology: insights from the bovine corneal endothelial cell system and beyond.

scientific article

Diagnostic and prognostic value of calcium oscillatory pattern analysis for patients with ICSI fertilization failure

scientific article published on 18 October 2012

Effect of flunarizine and methylprednisolone on functional recovery after experimental spinal injury

scientific article published in January 1993

Effects of flunarizine on induced calcium transients as measured in fura-2-loaded neurons of the rat dorsal root ganglion

scientific article published in September 1993

Efficacy of products to remove eggs of Pediculus humanus capitis (Phthiraptera: Pediculidae) from the human hair

scientific article published in March 2014

Electroporation Loading and Dye Transfer: A Safe and Robust Method to Probe Gap Junctional Coupling.

scientific article published in January 2016

Electroporation loading and flash photolysis to investigate intra- and intercellular Ca2+ signaling

scientific article published on 2 March 2015

Electroporation loading and photoactivation of caged InsP3: tools to investigate the relation between cellular ATP release in response to intracellular InsP3 elevation

scientific article published on January 2004

Electroporation loading of membrane-impermeable molecules to investigate intra- and intercellular Ca2+ signaling

scientific article

Endothelial calcium dynamics, connexin channels and blood-brain barrier function.

scientific article published on 10 July 2013

Engaging neuroscience to advance translational research in brain barrier biology.

scientific article published in March 2011

Erratum to: Manipulating Connexin Communication Channels: Use of Peptidomimetics and the Translational Outputs.

scientific article published on 15 September 2012

First and second messenger role of calcium. Survival versus apoptosis in serum-free cultured granulosa explants.

scientific article

Flash photolysis of caged IP3 to trigger intercellular Ca2+ waves

scientific article

Flow cytometric calcium flux assay: evaluation of cytoplasmic calcium kinetics in whole blood leukocytes.

scientific article published on 16 July 2009

Fluoxetine suppresses calcium signaling in human T lymphocytes through depletion of intracellular calcium stores

scientific article

Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis

scientific article

Gap junctional communication and connexin43 expression in relation to apoptotic cell death and survival of granulosa cells.

scientific article published in September 2004

Gap19, a Cx43 Hemichannel Inhibitor, Acts as a Gating Modifier That Decreases Main State Opening While Increasing Substate Gating

scientific article published on 05 October 2020

Gap26, a connexin mimetic peptide, inhibits currents carried by connexin43 hemichannels and gap junction channels

scientific article published on 21 February 2012

High frequency deep brain stimulation in the hippocampus modifies seizure characteristics in kindled rats

scientific article published on 22 March 2007

Hunting for connexin hemichannels.

scientific article published on 12 March 2014

IP3, a small molecule with a powerful message

scientific article published on 02 January 2013

In situ bipolar electroporation for localized cell loading with reporter dyes and investigating gap junctional coupling.

scientific article

Influence of methanandamide and CGRP on potassium currents in smooth muscle cells of small mesenteric arteries

scientific article published on 14 March 2012

Inhibiting connexin channels protects against cryopreservation-induced cell death in human blood vessels

scientific article

Inhibition of connexin hemichannels alleviates non-alcoholic steatohepatitis in mice

scientific article published on 15 August 2017

Inositol 1,4,5-trisphosphate receptor function in human oocytes: calcium responses and oocyte activation-related phenomena induced by photolytic release of InsP(3) are blocked by a specific antibody to the type I receptor.

scientific article

Inositol-trisphosphate-dependent intercellular calcium signaling in and between astrocytes and endothelial cells.

scientific article published on December 1998

Intercellular Ca2+Waves: Mechanisms and Function ⬇️

scientific article published on July 1, 2012

Intercellular calcium signaling and flash photolysis of caged compounds. A sensitive method to evaluate gap junctional coupling.

scientific article

Interstitial and tissue cations and electrical potential after experimental spinal cord injury

scientific article published in January 1994

Into rather unexplored terrain-transcellular transport across the blood-brain barrier

scientific article published on 8 February 2016

Intracellular Cleavage of the Cx43 C-Terminal Domain by Matrix-Metalloproteases: A Novel Contributor to Inflammation?

scientific article

Intracellular calcium changes trigger connexin 32 hemichannel opening ⬇️

scientific article published on 8 December 2005

Intracellular free calcium related to apoptotic cell death in quail granulosa cell sheets kept in serum-free culture

scientific article published in January 1997

Intracellular pH changes during zona drilling

scientific article published in February 1994

Intramolecular loop/tail interactions are essential for connexin 43-hemichannel activity

scientific article published on 15 July 2010

Ionic changes accompanying astrocytic intercellular calcium waves triggered by mechanical cell damaging stimulation

scientific article published in February 2000

L-beta-ODAP alters mitochondrial Ca2+ handling as an early event in excitotoxicity

scientific article

L-β-N-oxalyl-α,β-diaminopropionic acid toxicity in motor neurons.

scientific article published in February 2011

Low extracellular Ca2+ conditions induce an increase in brain endothelial permeability that involves intercellular Ca2+ waves

scientific article published on 10 July 2012

MRI-guided 3D conformal arc micro-irradiation of a F98 glioblastoma rat model using the Small Animal Radiation Research Platform (SARRP).

scientific article published on 29 July 2014

Manipulating connexin communication channels: use of peptidomimetics and the translational outputs

scientific article published on 11 August 2012

Method to measure force required to remove Pediculus humanus capitis (Phthiraptera: Pediculidae) eggs from human hair

scientific article published in January 2005

Mitochondrial Cx43 hemichannels contribute to mitochondrial calcium entry and cell death in the heart

scientific article published on 31 March 2017

Mitochondrial transmembrane potential changes support the concept of mitochondrial heterogeneity during apoptosis

scientific article published on October 2001

Negatively charged residues (Asp378 and Asp379) in the last ten amino acids of the C-terminal tail of Cx43 hemichannels are essential for loop/tail interactions

scientific article published on 29 January 2013

Neurological manifestations of oculodentodigital dysplasia: a Cx43 channelopathy of the central nervous system? ⬇️

scientific article published on 26 September 2013

Non-channel functions of connexins in cell growth and cell death

scientific article published on 22 June 2011

Nutrient Starvation Decreases Cx43 Levels and Limits Intercellular Communication in Primary Bovine Corneal Endothelial Cells

scientific article published on 12 February 2016

Opening of pannexin- and connexin-based channels increases the excitability of nodose ganglion sensory neurons

scientific article

Oscillatory Ca2+ dynamics and cell cycle resumption at fertilization in mammals: a modelling approach

scientific article published in January 2010

Pannexin 1 ohnologs in the teleost lineage.

scientific article published on 26 August 2012

Pannexin channels in ATP release and beyond: an unexpected rendezvous at the endoplasmic reticulum.

scientific article published on 03 August 2010

Pannexin1 as mediator of inflammation and cell death.

scientific article

Paracrine signaling through plasma membrane hemichannels

scientific article published on 13 July 2012

Peroxisome proliferator-activated receptor gamma activation alleviates postoperative ileus in mice by inhibition of Egr-1 expression and its downstream target genes

scientific article published on 5 August 2009

Perturbing plasma membrane hemichannels attenuates calcium signalling in cardiac cells and HeLa cells expressing connexins

scientific article

Pharmacological modulation of connexin‐formed channels in cardiac pathophysiology ⬇️

scientific article published on June 1, 2011

Pharmacological sensitivity of ATP release triggered by photoliberation of inositol-1,4,5-trisphosphate and zero extracellular calcium in brain endothelial cells

scientific article published on November 2003

Photoliberating inositol-1,4,5-trisphosphate triggers ATP release that is blocked by the connexin mimetic peptide gap 26.

scientific article published in January 2003

Proteomic and metabolomic responses to connexin43 silencing in primary hepatocyte cultures

scientific article published on 7 December 2012

Quantifying hemodynamic refractory bold effects in normal subjects at the single-subject level using an inverse logit fitting procedure

scientific article published in November 2011

Rapamycin prevents mesenteric neo-angiogenesis and reduces splanchnic blood flow in portal hypertensive mice

scientific article

Reduced amounts and abnormal forms of phospholipase C zeta (PLCzeta) in spermatozoa from infertile men.

scientific article published on 7 July 2009

Regulation of connexin- and pannexin-based channels by post-translational modifications.

scientific article published on 17 July 2013

Release of gliotransmitters through astroglial connexin 43 hemichannels is necessary for fear memory consolidation in the basolateral amygdala

scientific journal article

RhoA GTPase switch controls Cx43-hemichannel activity through the contractile system

scientific article

Role of symmetric dimethylarginine in vascular damage by increasing ROS via store-operated calcium influx in monocytes

scientific article

Ryanodine receptors are targeted by anti-apoptotic Bcl-XL involving its BH4 domain and Lys87 from its BH3 domain

scientific article

Selective inhibition of Cx43 hemichannels by Gap19 and its impact on myocardial ischemia/reperfusion injury.

scientific article published on 8 November 2012

Selective regulation of IP3-receptor-mediated Ca2+ signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl.

scientific article published on 5 August 2011

Simulated ischemia and intracellular pH in isolated ventricular muscle

scientific article published in August 1989

Single Ca (2+) transients versus oscillatory Ca(2+) signalling: limitations and benefits

scientific article

Structure, Regulation and Function of Gap Junctions in Liver.

scientific article published on 22 March 2016

TAT-Gap19 and Carbenoxolone Alleviate Liver Fibrosis in Mice.

scientific article

TNF/TNF-R1 pathway is involved in doxorubicin-induced acute sterile inflammation

scientific article published on 12 December 2013

Targeting MAPK phosphorylation of Connexin43 provides neuroprotection in stroke

scientific article published on 14 March 2019

Targeting gliovascular connexins prevents inflammatory blood-brain barrier leakage and astrogliosis

scientific article published in 2022

Technical note: the design of a stereotactic frame for direct MRI-anatomical correlation of the brachial plexus.

scientific article

The BH4 domain of anti-apoptotic Bcl-XL, but not that of the related Bcl-2, limits the voltage-dependent anion channel 1 (VDAC1)-mediated transfer of pro-apoptotic Ca2+ signals to mitochondria.

scientific article published on 13 February 2015

The connexin43 mimetic peptide Gap19 inhibits hemichannels without altering gap junctional communication in astrocytes

scientific article

The contractile system as a negative regulator of the connexin 43 hemichannel.

scientific article published on 04 April 2012

The dual face of connexin-based astroglial Ca(2+) communication: a key player in brain physiology and a prime target in pathology.

scientific article published on 21 April 2014

The gap junction cellular internet: connexin hemichannels enter the signalling limelight

scientific article published on July 2006

Transfer of IP₃ through gap junctions is critical, but not sufficient, for the spread of apoptosis

scientific article published on 25 November 2011

Tumour necrosis factor alpha inhibits purinergic calcium signalling in blood-brain barrier endothelial cells.

scientific article published on January 2004

Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity

scientific article published on 30 March 2016

Water-soluble CO-releasing molecules reduce the development of postoperative ileus via modulation of MAPK/HO-1 signalling and reduction of oxidative stress

scientific article published on 20 November 2008

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