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List of works by Ellen V. Rothenberg

A far downstream enhancer for murine Bcl11b controls its T-cell specific expression

scientific article (publication date: 8 August 2013)

A gene regulatory network armature for T lymphocyte specification

scientific article

A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment

A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment

scientific article published on 20 November 2018

A two-amino-acid substitution in the transcription factor RORγt disrupts its function in TH17 differentiation but not in thymocyte development.

scientific article published on 28 August 2017

Acquisition of mature functional responsiveness in T cells: programming for function via signaling

scientific article published on January 1991

An early T cell lineage commitment checkpoint dependent on the transcription factor Bcl11b

scientific article published on July 2010

Analysis of a 5' leader sequence on murine leukemia virus 21S RNA: heteroduplex mapping with long reverse transcriptase products

scientific article

Architecture of a lymphomyeloid developmental switch controlled by PU.1, Notch and Gata3.

scientific article published on March 2013

Asynchronous combinatorial action of four regulatory factors activates Bcl11b for T cell commitment

scientific article

B cell specification from the genome up.

scientific article published in July 2010

Bcl11b and combinatorial resolution of cell fate in the T-cell gene regulatory network

scientific article

Bcl11b sets pro-T cell fate by site-specific cofactor recruitment and by repressing Id2 and Zbtb16

scientific article published on 30 October 2018

Building a Human Thymus: A Pointillist View

scientific article published on 01 November 2019

Causal Gene Regulatory Network Modeling and Genomics: Second-Generation Challenges

article

Cell lineage regulators in B and T cell development

scientific article published on May 2007

Cell type-specific actions of Bcl11b in early T-lineage and group 2 innate lymphoid cells

scientific article published on 01 January 2020

Cell-type-specific activation and repression of PU.1 by a complex of discrete, functionally specialized cis-regulatory elements

scientific article (publication date: October 2010)

Cell-type-specific epigenetic marking of the IL2 gene at a distal cis-regulatory region in competent, nontranscribing T-cells

scientific article

Chromatin remodeling of the interleukin-2 gene: distinct alterations in the proximal versus distal enhancer regions

scientific article published on June 1998

Competition and collaboration: GATA-3, PU.1, and Notch signaling in early T-cell fate determination

scientific article published on August 2008

Computational modelling of T-cell formation kinetics: output regulated by initial proliferation-linked deferral of developmental competence

scientific article published in January 2013

Constitutive expression of PU.1 in fetal hematopoietic progenitors blocks T cell development at the pro-T cell stage

scientific article published in February 2002

Core binding factors are necessary for natural killer cell development and cooperate with Notch signaling during T-cell specification

scientific article published on 4 April 2008

Costimulation by interleukin-1 of multiple activation responses in a developmentally restricted subset of immature thymocytes.

scientific article published in January 1994

Cross-lineage expression of Ig-β (B29) in thymocytes: Positive and negative gene regulation to establish T cell identity ⬇️

scientific article published on June 9, 1998

Cytokines, Transcription Factors, and the Initiation of T-Cell Development

scientific article

Decision by committee: new light on the CD4/CD8-lineage choice

scientific article published on 16 December 2008

Definition of regulatory network elements for T cell development by perturbation analysis with PU.1 and GATA-3.

scientific article

Delayed, asynchronous, and reversible T-lineage specification induced by Notch/Delta signaling

scientific article published on April 2005

Deranged early T cell development in immunodeficient strains of nonobese diabetic mice

scientific article published in November 2004

Developmental and anatomical patterns of IL-2 gene expression in vivo in the murine thymus

scientific article published on January 1993

Developmental and molecular characterization of emerging beta- and gammadelta-selected pre-T cells in the adult mouse thymus

scientific article published in January 2006

Developmental biologist Eric H. Davidson, 1937-2015

scientific article

Developmental gene networks: a triathlon on the course to T cell identity

scientific article

Differential regulation of T cell receptor gamma genes in immature thymocyte populations

scientific article published in September 1987

Differential transient and long-term expression of DNA sequences introduced into T-lymphocyte lines

scientific article published in December 1986

Differentiation and cell division in the mammalian thymus

scientific article

Dynamic control of the T-cell specification gene regulatory network

scientific article published on 06 November 2019

Dynamic transformations of genome-wide epigenetic marking and transcriptional control establish T cell identity

scientific article published on April 2012

Editorial overview

scientific article published on 19 March 2010

Elements of transcription factor network design for T-lineage specification

scientific article

Encounters across networks: Windows into principles of genomic regulation

Epigenetic mechanisms and developmental choice hierarchies in T-lymphocyte development ⬇️

scientific article published on August 6, 2013

Erg in stem cells: a function emerges

scientific article published on 01 July 2008

Eric Davidson: Steps to a gene regulatory network for development

scientific article published on 26 January 2016

Evolutionary origins of lymphocytes: ensembles of T cell and B cell transcriptional regulators in a cartilaginous fish

scientific article published in May 2004

Expression and function of a stem cell promoter for the murine CBFalpha2 gene: distinct roles and regulation in natural killer and T cell development.

scientific article

Expression of differentiation antigens in subpopulations of mouse thymocytes: Regulation at the level of de novo synthesis

scientific article published on 01 May 1980

Fine-scale staging of T cell lineage commitment in adult mouse thymus

scientific article

Fitting structure to function in gene regulatory networks

scientific article published on 16 October 2017

Forging T-Lymphocyte Identity: Intersecting Networks of Transcriptional Control

scientific article

From totipotency to T in a dish

scientific article published in April 2004

GATA-3 dose-dependent checkpoints in early T cell commitment

scientific article

GATA-3 expression is controlled by TCR signals and regulates CD4/CD8 differentiation

scientific article published in July 2003

GATA-3 locks the door to the B-cell option ⬇️

scientific article published on March 7, 2013

GATA3 induces human T-cell commitment by restraining Notch activity and repressing NK-cell fate

scientific article published on 6 April 2016

Gene Regulation in T-Cell Lineage Commitment

article

Genetic polymorphism of murineβ 2-microglobulin detected biochemically

scientific article published on 01 July 1980

Hematopoiesis and T-cell specification as a model developmental system

scientific article published on May 2016

Heteroduplex analysis of the nonhomology region between Moloney MuLV and the dual host range derivative HIX virus

scientific article published on August 1978

High frequency of aberrant expression of Moloney murine leukemia virus in clonal infections

scientific article

How T cells count

scientific article published on July 1996

How haematopoiesis research became a fertile ground for regulatory network biology as pioneered by Eric Davidson

scientific article published on 21 November 2020

How transcription factors drive choice of the T cell fate

scientific article published on 11 September 2020

Ikaros represses and activates PU.1 cell-type-specifically through the multifunctional Sfpi1 URE and a myeloid specific enhancer

scientific article published on 9 January 2012

Illuminating the core of adaptive immunity-how the regulatory genome controls Rag chromatin dynamics

scientific article published on 01 September 2020

Immune Cell Identity: Perspective from a Palimpsest

scientific article published on January 2015

Immunology. Thymic regulation--hidden in plain sight

scientific article published in February 2005

In vitro maintenance of differentiation marker synthesis by subpopulations of mouse thymocytes

scientific article published on 01 January 1980

In vitro synthesis of infectious DNA of murine leukaemia virus

scientific article

Irreversibility of T-Cell Specification: Insights from Computational Modelling of a Minimal Network Architecture

scientific article

Launching the T-cell-lineage developmental programme

scientific article published on January 2008

Lck activity controls CD4/CD8 T cell lineage commitment.

scientific article published on March 2000

Lineage determination in the immune system ⬇️

scientific article published on November 1, 2010

Lineage divergence at the first TCR-dependent checkpoint: preferential γδ and impaired αβ T cell development in nonobese diabetic mice

scientific article

Lineage plasticity and commitment in T-cell development

scientific article

Localization of the domains in Runx transcription factors required for the repression of CD4 in thymocytes

scientific article published in April 2004

Loss of T cell progenitor checkpoint control underlies leukemia initiation in Rag1-deficient nonobese diabetic mice

scientific article published on 25 February 2013

Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3

scientific journal article

Mechanisms of Action of Hematopoietic Transcription Factor PU.1 in Initiation of T-Cell Development

article

Molecular dissection of prethymic progenitor entry into the T lymphocyte developmental pathway

scientific article

Molecular genetics of T cell development

scientific article

Molecular indices of functional competence in developing T cells

scientific article published on August 1988

Molecular mechanisms that control mouse and human TCR-alphabeta and TCR-gammadelta T cell development

scientific article published on 17 October 2008

Multilayered specification of the T-cell lineage fate

scientific article

Multiple Curricula for B Cell Developmental Programming

scientific article published in September 2016

Negotiation of the T lineage fate decision by transcription-factor interplay and microenvironmental signals

scientific article published on June 2007

Notch/Delta signaling constrains reengineering of pro-T cells by PU.1.

scholarly article

Notch2 complements Notch1 to mediate inductive signaling that initiates early T cell development

scientific article published on 01 October 2020

Notchless T cell maturation?

scientific article published on 01 March 2001

Ordered transcription of RNA tumor virus genomes ⬇️

scientific article published on September 5, 1976

Origins of lymphocyte developmental programs: transcription factor evidence

scientific article

Pioneering, chromatin remodeling, and epigenetic constraint in early T-cell gene regulation by PU.1

article

Pioneering, chromatin remodeling, and epigenetic constraint in early T-cell gene regulation by SPI1 (PU.1)

article

Positive feedback between PU.1 and the cell cycle controls myeloid differentiation

scientific article published on 18 July 2013

Precocious expression of T cell functional response genes in vivo in primitive thymocytes before T lineage commitment

scientific article published in November 1998

Preferential activation of an IL-2 regulatory sequence transgene in TCR gamma delta and NKT cells: subset-specific differences in IL-2 regulation

scientific article published in April 2004

Programming for T-lymphocyte fates: modularity and mechanisms

scientific article published on 01 September 2019

Progression of regulatory gene expression states in fetal and adult pro-T-cell development

scientific article

Radiation leukemia virus and X-irradiation induce in C57BL/6 mice two distinct T-cell neoplasms: a growth factor-dependent lymphoma and a growth factor-independent lymphoma

scientific article

Regulation of early T-lineage gene expression and developmental progression by the progenitor cell transcription factor PU.1.

scientific article

Regulatory Co-options in the Evolution of Deuterostome Immune Systems

Regulatory anatomy of the murine interleukin-2 gene

scientific article published on August 1990

Regulatory coding of lymphoid lineage choice by hematopoietic transcription factors

scientific article

Regulatory factors for initial T lymphocyte lineage specification

scientific article published on July 2007

Regulatory gene network circuits underlying T cell development from multipotent progenitors

scientific article

Signaling mechanisms in thymocyte selection

scientific article

Single-Cell Analysis Reveals Regulatory Gene Expression Dynamics Leading to Lineage Commitment in Early T Cell Development

scientific article published on 16 October 2019

Specific regulation of fos family transcription factors in thymocytes at two developmental checkpoints

scientific article published on May 1999

Stepwise specification of lymphocyte developmental lineages.

scientific article published in August 2000

Structure and expression of glycoproteins controlled by the Qa-1 a allele

scientific article published on 01 December 1981

Subversion of T lineage commitment by PU.1 in a clonal cell line system

scientific article

T Cell Lineage Commitment: Identity and Renunciation ⬇️

scientific article published on June 15, 2011

T-cell identity and epigenetic memory

scientific article published on January 2012

T-lineage specification and commitment: a gene regulation perspective

scientific article

TET proteins regulate the lineage specification and TCR-mediated expansion of iNKT cells

scientific article published on 21 November 2016

The basic helix-loop-helix transcription factor HEBAlt is expressed in pro-T cells and enhances the generation of T cell precursors

scientific article published in July 2006

The chromatin landscape and transcription factors in T cell programming

scientific article published on 02 April 2014

The development of functionally responsive T cells

scientific article

The long road to functional maturity for developing T cells

scientific article published on 01 April 1989

Transcription Factor PU.1 Represses and Activates Gene Expression in Early T Cells by Redirecting Partner Transcription Factor Binding

scientific article published on 01 October 2018

Transcription Factor PU.1 Represses and Activates Gene Expression in Early T Cells by Redirecting Partner Transcription Factor Binding

scientific article published on 01 June 2018

Transcription factor expression dynamics of early T-lymphocyte specification and commitment

scientific article published on 5 November 2008

Transcriptional Regulation of T Cell Lineage Commitment

Transcriptional control of early T and B cell developmental choices

scientific article published on 22 January 2014

Transcriptional drivers of the T-cell lineage program ⬇️

scientific article published on January 19, 2012

Transcriptional establishment of cell-type identity: dynamics and causal mechanisms of T-cell lineage commitment

scientific article

Transformation of Accessible Chromatin and 3D Nucleome Underlies Lineage Commitment of Early T Cells.

scientific article published in February 2018

What is the role of T-lymphocyte surveillance in neoplastic disease?

scientific article published on 01 June 1982

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