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List of works by Michele Caraglia

5-Fluorouracil induces apoptosis in rat cardiocytes through intracellular oxidative stress.

scientific article

8-Cl-cAMP antagonizes mitogen-activated protein kinase activation and cell growth stimulation induced by epidermal growth factor.

scientific article published on December 1999

A Hydroquinone-Based Derivative Elicits Apoptosis and Autophagy via Activating a ROS-Dependent Unfolded Protein Response in Human Glioblastoma

scientific article published on 06 August 2019

A Long-term Treatment with Silybin in Patients with Non-alcoholic Steatohepatitis Stimulates Catalase Activity in Human Endothelial Cells

scientific article published on July 2017

A hitherto unreported high incidence of zoledronic acid-induced acute phase reaction in patients with cancer treatment-induced bone loss

scientific article published on 04 October 2006

A liver angioma colonized by colon cancer cells in a patient with two primitive localizations by colon adenocarcinoma: biologic, diagnostic and therapeutic implications

scientific article published on 20 July 2005

A mechanistic study on the cardiotoxicity of 5-fluorouracil in vitro and clinical and occupational perspectives

scientific article

A miRNA signature suggestive of nodal metastases from laryngeal carcinoma

scientific article published in December 2017

A multidisciplinary approach is required to increase the quality of phase II/III clinical studies on biotherapies in oncology

scientific article published on 16 April 2007

A new inhibitor of glucose-6-phosphate dehydrogenase blocks pentose phosphate pathway and suppresses malignant proliferation and metastasis in vivo.

scientific article

A new schedule of fotemustine in temozolomide-pretreated patients with relapsing glioblastoma.

scientific article

A systematic review and meta-analysis of randomized trials on the role of targeted therapy in the management of advanced gastric cancer: Evidence does not translate?

scientific article

Acetylation of proteins as novel target for antitumor therapy: review article.

scientific article published on 11 June 2004

Acquired resistance to zoledronic acid and the parallel acquisition of an aggressive phenotype are mediated by p38-MAP kinase activation in prostate cancer cells

scientific article published on 23 May 2013

Acquired resistance to zoledronic acid and the parallel acquisition of an aggressive phenotype are mediated by p38-MAP kinase activation in prostate cancer cells.

scientific article published on 5 June 2014

Adenylate cyclase/cAMP pathway downmodulation counteracts apoptosis induced by IFN-alpha in human epidermoid cancer cells.

scientific article published on February 2007

AdoMet triggers apoptosis in head and neck squamous cancer by inducing ER stress and potentiates cell sensitivity to cisplatin

scientific article published on 21 December 2018

Advantages and risks of nanotechnologies in cancer patients and occupationally exposed workers.

scientific article published on 29 April 2014

Aggressiveness pattern and second primary tumor risk associated with basaloid squamous cell carcinoma of the larynx

scientific article published on 28 September 2017

Alpha-interferon induces depletion of intracellular iron content and upregulation of functional transferrin receptors on human epidermoid cancer KB cells

scientific article published on 01 August 1994

Alternative therapy of earth elements increases the chondroprotective effects of chondroitin sulfate in mice.

scientific article published in October 2005

Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics

scientific journal article

Anaplastic lymphoma kinase: a glimmer of hope in lung cancer treatment?

scientific article published on April 2013

Antagonistic effects of chloroquine on autophagy occurrence potentiate the anticancer effects of everolimus on renal cancer cells

scientific article

Anti-Inflammatory Drugs as Anticancer Agents

scientific article published on 09 April 2020

Anti-cancer activity of dose-fractioned mPE +/- bevacizumab regimen is paralleled by immune-modulation in advanced squamous NSLC patients.

scientific article published in September 2017

Anticancer drugs and hyperthermia enhance cytotoxicity induced by polyamine enzymatic oxidation products.

scientific article published on 4 July 2007

Antiproliferative effects of ruthenium-based nucleolipidic nanoaggregates in human models of breast cancer in vitro: insights into their mode of action.

scientific article published on 28 March 2017

Antitumor activity of interferon-β1a in hormone refractory prostate cancer with neuroendocrine differentiation.

scientific article

Antitumor therapeutic strategies based on the targeting of epidermal growth factor-induced survival pathways.

scientific article

Apoptosis induced by interferon-alpha and antagonized by EGF is regulated by caspase-3-mediated cleavage of gelsolin in human epidermoid cancer cells.

scientific article published on October 2004

Apoptotic index or a combination of Bax/Bcl-2 expression correlate with survival after resection of pancreatic adenocarcinoma.

scientific article

Atrial fibrillation following chemotherapy for stage IIIE diffuse large B-cell gastric lymphoma in a patient with myotonic dystrophy (Steinert's disease).

scientific article published on 23 March 2004

Atypical amplification of chromosome region 22q12 in melanoma: A case report

scientific article published on 27 April 2015

Atypical cutaneous lymphoid hyperplasia induced by chemotherapy in a patient with advanced colon carcinoma

scientific article published in November 2007

Autophagy induction by trehalose: Molecular mechanisms and therapeutic impacts.

scientific article published on 16 April 2018

BAG3 is a novel serum biomarker for pancreatic adenocarcinomas.

scientific article

BK Virus Infection and BK-Virus-Associated Nephropathy in Renal Transplant Recipients

scientific article published on 21 July 2022

BRAF and PIK3CA genes are somatically mutated in hepatocellular carcinoma among patients from South Italy

scientific article published on 19 January 2012

Body mass index and impaired fasting blood glucose as predictive factor of time to progression (TTP) in cetuximab-based colorectal cancer treatment.

scientific article published on June 2013

Bovine serum amine oxidase and spm potentiate docetaxel and interferon-alpha effects in inducing apoptosis on human cancer cells through the generation of oxidative stress.

scientific article published on 20 September 2008

Breast Cancer Chemotherapeutic Options: A General Overview on the Preclinical Validation of a Multi-Target Ruthenium(III) Complex Lodged in Nucleolipid Nanosystems

scientific article published on 05 June 2020

Breast MALT lymphomas: a clinicopathological and cytogenetic study of 9 cases

scientific article published on 27 July 2012

C-Raf antagonizes apoptosis induced by IFN-alpha in human lung cancer cells by phosphorylation and increase of the intracellular content of elongation factor 1A.

scientific article

CXCR4 and CXCR7 transduce through mTOR in human renal cancer cells

scientific article

CXCR4-antagonist Peptide R-liposomes for combined therapy against lung metastasis.

scientific article published on 17 March 2016

Calcitriol: a better option than vitamin D in denosumab-treated patients with kidney failure?

scientific article published on 25 December 2012

Cancer prevalence in the city of Naples: Contribution of the GP database analyses to the cancer registries network.

scientific article published on 04 April 2013

Carbon nanotubes: Properties, biomedical applications, advantages and risks in patients and occupationally-exposed workers.

scientific article

Carcinogenetic mechanisms of endocrine disruptors in female cancers (Review)

scientific article

Cetuximab is an active treatment of metastatic and chemorefractory thymoma.

scientific article published in January 2007

Cetuximab ± chemotherapy enhances dendritic cell-mediated phagocytosis of colon cancer cells and ignites a highly efficient colon cancer antigen-specific cytotoxic T-cell response in vitro.

scientific article published on 16 August 2011

Change in TNF-alpha receptor expression is a relevant event in doxorubicin-induced H9c2 cardiomyocyte cell death.

scientific article

Changes in bone resorption and vascular endothelial growth factor after a single zoledronic acid infusion in cancer patients with bone metastases from solid tumours

scientific article published on May 2006

CheckMate 141 trial: all that glitters is not gold

scientific article published on 21 January 2019

Chemotherapy in the management of brain metastases: the emerging role of fotemustine for patients with melanoma and NSCLC.

scientific article published on 08 April 2013

Chemotherapy regimen GOLF induces apoptosis in colon cancer cells through multi-chaperone complex inactivation and increased Raf-1 ubiquitin-dependent degradation

scientific article published on 23 October 2005

Chitosan-coated liposomes loaded with butyric acid demonstrate anticancer and anti-inflammatory activity in human hepatoma HepG2 cells

scientific article published on 13 December 2018

Chondroitin sulphate enhances the antitumor activity of gemcitabine and mitomycin-C in bladder cancer cells with different mechanisms

scientific article

Cigarette smoking habit does not reduce the benefit from first line trastuzumab-based treatment in advanced breast cancer patients.

scientific article published on 28 March 2011

Circadian rhythms, adrenergic hormones and trafficking of hematopoietic stem cells.

scientific article published on May 2010

Clinical Practice Use of Liquid Biopsy to Identify RAS/BRAF Mutations in Patients with Metastatic Colorectal Cancer (mCRC): A Single Institution Experience

scientific article published on 08 October 2019

Combined magnetic resonance spectroscopy and dynamic contrast-enhanced imaging for prostate cancer detection

scientific article

Combined treatment with PPAR-γ agonists in pancreatic cancer: a glimmer of hope for cancer therapy?

scientific article published on May 2013

Combined use of free light chain and heavy/light chain ratios allow diagnosis and monitoring of patients with monoclonal gammopathies: Experience of a single institute, with three exemplar case reports

scientific article published on 5 August 2016

Combining temozolomide with other antitumor drugs and target-based agents in the treatment of brain metastases: an unending quest or chasing a chimera?

scientific article published on 02 May 2011

Concomitant occurrence of facial cutaneous and parotid gland metastases from rectal cancer after preoperative chemoradiotherapy

scientific article published on 29 May 2007

Concomitant treatment of brain metastasis with whole brain radiotherapy [WBRT] and temozolomide [TMZ] is active and improves quality of life

scientific article

Conditions Suggesting Lymphoma

scientific article published on 01 June 2005

Core-shell biodegradable nanoassemblies for the passive targeting of docetaxel: features, antiproliferative activity and in vivo toxicity

scientific article

Correction: Metabolic syndrome, endocrine disruptors and prostate cancer associations: biochemical and pathophysiological evidences.

scientific article published on 22 September 2017

Could PD-1/PDL1 immune checkpoints be linked to HLA signature?

scientific article published on 09 December 2019

Critical role of both p27KIP1 and p21CIP1/WAF1 in the antiproliferative effect of ZD1839 ('Iressa'), an epidermal growth factor receptor tyrosine kinase inhibitor, in head and neck squamous carcinoma cells

scientific article published in April 2003

Current approaches and perspectives in the therapy of medullary thyroid carcinoma

scientific article

Current treatment of cutaneous squamous cancer and molecular strategies for its sensitization to new target-based drugs.

scientific article published on 24 September 2012

Cyclohexa-2,5-diene-1,4-dione-based antiproliferative agents: design, synthesis, and cytotoxic evaluation.

scientific article published on 30 April 2013

Cyr61 downmodulation potentiates the anticancer effects of zoledronic acid in androgen-independent prostate cancer cells

scientific article

Cytosine arabinoside (Ara-C) plus alpha-interferon (alpha IFN) determine prolonged complete remissions in patients with aggressive non-Hodgkin's lymphoma partially responsive to first-line doxorubicin-containing regimens

scientific article published on 01 October 1994

Cytosine arabinoside increases the binding of 125I-labelled epidermal growth factor and 125I-transferrin and enhances the in vitro targeting of human tumour cells with anti-(growth factor receptor) mAb

scientific article published on 01 August 1993

Cytotoxic drugs up-regulate epidermal growth factor receptor (EGFR) expression in colon cancer cells and enhance their susceptibility to EGFR-targeted antibody-dependent cell-mediated-cytotoxicity (ADCC).

scientific article published on June 2010

DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma.

scientific article published on October 2012

Daily low-dose subcutaneous recombinant interleukin-2 by alternate weekly administration: antitumor activity and immunomodulatory effects

scientific article published on 01 February 1998

Dendritic cell-mediated cross-presentation of antigens derived from colon carcinoma cells exposed to a highly cytotoxic multidrug regimen with gemcitabine, oxaliplatin, 5-fluorouracil, and leucovorin, elicits a powerful human antigen-specific CTL re

scientific article published on July 2005

Denosumab: the era of targeted therapies in bone metastatic diseases

scientific article

Desferioxamine increases iron depletion and apoptosis induced by ara-C of human myeloid leukaemic cells

scientific article published in August 1998

Determination of miRNAs from Cancer Stem Cells Using a Low Density Array Platform.

scientific article published in January 2018

Dickkopf Homolog 3 (DKK3): a candidate for detection and treatment of cancers?

scientific article published on 5 December 2017

Dicrocoelium dendriticum induces autophagic vacuoles accumulation in human hepatocarcinoma cells.

scientific article published on 6 August 2015

Distinctive germline expression of class I human leukocyte antigen (HLA) alleles and DRB1 heterozygosis predict the outcome of patients with non-small cell lung cancer receiving PD-1/PD-L1 immune checkpoint blockade

scientific article published on 01 June 2020

Dose/dense metronomic chemotherapy with fractioned cisplatin and oral daily etoposide enhances the anti-angiogenic effects of bevacizumab and has strong antitumor activity in advanced non-small-cell-lung cancer patients.

scientific article published on May 2010

Drug-Drug Interactions Based on Pharmacogenetic Profile between Highly Active Antiretroviral Therapy and Antiblastic Chemotherapy in Cancer Patients with HIV Infection

scientific article

EGF activates an inducible survival response via the RAS-> Erk-1/2 pathway to counteract interferon-alpha-mediated apoptosis in epidermoid cancer cells.

scientific article

EGF-R small inhibitors and anti-EGF-R antibodies: advantages and limits of a new avenue in anticancer therapy.

scientific article published on June 2006

EGFR mutational status in penile cancer.

scientific article published on 22 March 2013

EZH2 is increased in paediatric T-cell acute lymphoblastic leukemia and is a suitable molecular target in combination treatment approaches

scientific article

Early skin toxicity as a predictive factor for tumor control in hepatocellular carcinoma patients treated with sorafenib

scientific article published on 5 January 2010

Effect of small molecules modulating androgen receptor (SARMs) in human prostate cancer models

scientific article

Effects of VIP and VIP-DAP on proliferation and lipid peroxidation metabolism in human KB cells.

scientific article published on July 2006

Effects of statins and farnesyl transferase inhibitors on ERK phosphorylation, apoptosis and cell viability in non-small lung cancer cells

scientific article

Electromagnetic fields at mobile phone frequency induce apoptosis and inactivation of the multi-chaperone complex in human epidermoid cancer cells.

scientific article published on August 2005

Emerging anti-cancer molecular mechanisms of aminobisphosphonates

scientific article

Emerging pathways as individualized therapeutic target of multiple myeloma.

scientific article published on 06 June 2013

Emerging strategies to strengthen the anti-tumour activity of type I interferons: overcoming survival pathways.

scientific article published on August 2009

Endocrine disruptors and female cancer: Informing the patients (Review).

scientific article published on 20 May 2015

Epigenetic changes induced by green tea catechins are associated with prostate cancer.

scientific article published on 18 December 2017

Epigenetic fingerprint in endometrial carcinogenesis: the hypothesis of a uterine field cancerization

scientific article published in September 2011

Erlotinib: early clinical development in brain cancer

scientific article published on 16 May 2014

Erratum to: A new schedule of fotemustine in temozolomide-pretreated patients with relapsing glioblastoma

scholarly article published in Journal of Neuro-Oncology

Erratum to: PI3K/Akt/mTOR signaling in medullary thyroid cancer: a promising molecular target for cancer therapy.

scientific article

Erratum to: The methyl donor S-adenosylmethionine potentiates doxorubicin effects on apoptosis of hormone-dependent breast cancer cell lines.

scientific article

Evaluation of the efficacy of potential antineoplastic drugs on tumour metastasis by a computer-assisted image analysis

scientific article published on 01 August 2000

Evaluation of the in vitro and in vivo antiangiogenic effects of denosumab and zoledronic acid

scientific article published on 18 September 2012

Everolimus is an active agent in medullary thyroid cancer: a clinical and in vitro study.

scientific article published on July 2012

Evidence of novel miR-34a-based therapeutic approaches for multiple myeloma treatment.

scientific article published on 20 December 2017

Evolution of Mutational Landscape and Tumor Immune-Microenvironment in Liver Oligo-Metastatic Colorectal Cancer

scientific article published on 21 October 2020

Experimental study on vasoactive intestinal peptide (VIP) and its diaminopropane bound (VIP-DAP) analog in solution.

scientific article published on 6 July 2007

Exploitation of viral properties for intracellular delivery

scientific article published on 30 May 2014

Exploring cellular uptake, accumulation and mechanism of action of a cationic Ru-based nanosystem in human preclinical models of breast cancer

scientific article published on 07 May 2019

Exploring the efficacy and safety of single-agent sorafenib in a cohort of Italian patients with hepatocellular carcinoma

scientific article published on 24 October 2012

Expression and localization of serine protease Htra1 in neuroblastoma: correlation with cellular differentiation grade

scientific article published on 04 February 2014

Extracellular Vesicles: New Endogenous Shuttles for miRNAs in Cancer Diagnosis and Therapy?

scientific article published on 04 September 2020

Extracellular adenosine 5' triphosphate involvement in the death of LAK-engaged human tumor cells via P2X-receptor activation

scientific article published on February 1997

FOLFOXIRI in metastatic colorectal cancer: A criticism from its native land.

scientific article published on 24 August 2017

Familial papillary thyroid microcarcinoma: a new clinical entity

scientific article published on 01 February 1999

Fasting inhibits hepatic stellate cells activation and potentiates anti-cancer activity of Sorafenib in hepatocellular cancer cells.

scientific article

First Biologic Drug in the Treatment of RAS Wild-Type Metastatic Colorectal Cancer: Anti-EGFR or Bevacizumab? Results From a Meta-Analysis.

scientific article published on 3 May 2018

Fotemustine and recurrent glioblastoma: possible new opportunities for an old drug.

scientific article published on 29 July 2009

From Protein Synthesis to Molecular Biology: The Appealing Tale of eIF-5A.

scientific article published on 7 October 2014

GPR30 is overexpressed in post-puberal testicular germ cell tumors

scientific article published on 15 March 2011

Gamma-glutamyl 16-diaminopropane derivative of vasoactive intestinal peptide: a potent anti-oxidative agent for human epidermoid cancer cells.

scientific article

Gemcitabine (GEM) plus oxaliplatin, folinic acid, and 5-fluorouracil (FOLFOX-4) in patients with advanced gastric cancer.

scientific article published on 23 July 2005

Gemcitabine, oxaliplatin, levofolinate, 5-fluorouracil, granulocyte-macrophage colony-stimulating factor, and interleukin-2 (GOLFIG) versus FOLFOX chemotherapy in metastatic colorectal cancer patients: the GOLFIG-2 multicentric open-label randomized

scientific article published on January 2014

Gene interference strategies as a new tool for the treatment of prostate cancer

scientific article published on 07 June 2015

Genetic trajectory and immune microenvironment of lung-specific oligometastatic colorectal cancer

scientific article published on 24 April 2020

Genotype-based therapeutic approach for colorectal cancer: state of the art and future perspectives

scientific article published on 01 May 2009

Glucocorticoids induce G1 arrest of lymphoblastic cells through retinoblastoma protein Rb1 dephosphorylation in childhood acute lymphoblastic leukemia in vivo.

scientific article published on 9 May 2004

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

HDAC inhibitor vorinostat enhances the antitumor effect of gefitinib in squamous cell carcinoma of head and neck by modulating ErbB receptor expression and reverting EMT.

scientific article published on September 2011

HLA Expression Correlates to the Risk of Immune Checkpoint Inhibitor-Induced Pneumonitis

scientific article published on 25 August 2020

Hepatocarcinoma: genetic and epigenetic features

scientific article

High EZH2 expression is correlated to metastatic disease in pediatric soft tissue sarcomas.

scientific article published on 28 July 2016

High concordance of BRAF status between primary colorectal tumours and related metastatic sites: implications for clinical practice

scientific article published on 01 July 2010

High throughput screening for inhibitors of the HECT ubiquitin E3 ligase ITCH identifies antidepressant drugs as regulators of autophagy

scientific article published on May 2014

High-dose recombinant interleukin-2/verapamil combination in advanced cancer

scientific article published on 01 July 1996

Highlights of regional meeting of Italian Southern Oncological Group (GOIM): focus on hepatocellular carcinoma: biological and clinical background, therapeutic guide-lines and perspectives. 7 November 2008, Naples, Italy

scientific article published on 01 March 2009

Highlights of the Annual Meeting of the Italian Association for Cell Cultures (AICC): new drug delivery strategies and technological platforms for diagnosis and therapy of tumors. Part II. 6 - 7 December 2007, Naples, Italy

scientific article published on 01 July 2008

Highlights of the Pananemia National Meeting of the Italian Southern Oncological Group (GOIM): pharmacological and molecular treatment of cancer-induced anemia. Sorrento, Italy, 19-20 December 2008

scientific article published on 01 April 2009

Highlights of the annual meeting of the Italian Association for Cell Cultures (AICC): new drug delivery strategies and technological platforms for diagnosis and therapy of tumors (Part I) 6 - 7 December 2007, Naples, Italy

scientific article published on 01 June 2008

Histomorphologic parameters and CXCR4 mRNA and protein expression in sentinel node melanoma metastasis are correlated to clinical outcome

scientific article published on 20 March 2010

Histone deacetylase inhibitors: a new wave of molecular targeted anticancer agents.

scientific article published on June 2007

HtrA1 loss is related to aggressive behavior parameters in sentinel node positive breast cancer

scientific article published on 22 December 2014

Human equilibrative nucleoside transporter 1 (hENT1) levels predict response to gemcitabine in patients with biliary tract cancer (BTC).

scientific article published on January 2011

Hydrogen sulfide reduces cell adhesion and relevant inflammatory triggering by preventing ADAM17-dependent TNF-α activation

scientific article

Immune-modulating effects of the newest cetuximab-based chemoimmunotherapy regimen in advanced colorectal cancer patients.

scientific article published on June 2012

Immunotherapy of colorectal cancer: new perspectives after a long path.

scientific article published on November 2016

Impact of anemia management with EPO on psychologic distress in cancer patients: results of a multicenter patient survey

scientific article published on January 2014

Impairment of the metastatic activity of melanoma cells by transglutaminase-catalyzed incorporation of polyamines into laminin and Matrigel

scientific article published on 14 March 2007

In vitro anticancer activity of docetaxel-loaded micelles based on poly(ethylene oxide)-poly(epsilon-caprolactone) block copolymers: Do nanocarrier properties have a role?

scientific article published on 8 September 2010

In vivo activity of miR-34a mimics delivered by stable nucleic acid lipid particles (SNALPs) against multiple myeloma

scientific article

In vivo anti-myeloma activity and modulation of gene expression profile induced by valproic acid, a histone deacetylase inhibitor.

scientific article

Insight toward the MicroRNA Profiling of Laryngeal Cancers: Biological Role and Clinical Impact ⬇️

scientific article published on 24 May 2020

Interferon alpha2 recombinant and epidermal growth factor modulate proliferation and hypusine synthesis in human epidermoid cancer KB cells.

scientific article published on June 1997

Interferon-alpha induces apoptosis in human KB cells through a stress-dependent mitogen activated protein kinase pathway that is antagonized by epidermal growth factor

scientific article published on 01 August 1999

Interleukin 18: friend or foe in cancer

scientific article published on 08 October 2013

Interleukin 1beta-511T gene (IL1beta) polymorphism is correlated with gastric cancer in the Caucasian population: results from a meta-analysis

scientific article published in November 2008

Interleukin-2 and lanreotide in the treatment of medullary thyroid cancer: in vitro and in vivo studies

scientific article published on 24 July 2013

Intrinsic resistance to selumetinib, a selective inhibitor of MEK1/2, by cAMP-dependent protein kinase A activation in human lung and colorectal cancer cells ⬇️

scientific article published on May 8, 2012

Ipilimumab for the treatment of metastatic prostate cancer

scientific article published on 22 December 2017

Isoprenylation of intracellular proteins as a new target for the therapy of human neoplasms: preclinical and clinical implications.

scientific article

Keratin 5 expression in squamocellular carcinoma of the head and neck

scientific article

Last generation of amino-bisphosphonates (N-BPs) and cancer angio-genesis: a new role for these drugs?

scientific article

Latest developments in targeted therapy for hepatocellular carcinoma.

scientific article published on October 2010

Levofolene modulates apoptosis induced by 5-fluorouracil through autophagy inhibition: clinical and occupational implications.

scientific article

Liposomal pegylated doxorubicin plus vinorelbine combination as first-line chemotherapy for metastatic breast cancer in elderly women > or = 65 years of age.

scientific article published on 9 October 2007

Liposome armed with herpes virus-derived gH625 peptide to overcome doxorubicin resistance in lung adenocarcinoma cell lines

scientific article

Lovastatin induces apoptosis of k-ras-transformed thyroid cells via inhibition of ras farnesylation and by modulating redox state

scientific article published on 9 September 2008

Low-dose metronomic oral administration of vinorelbine in the first-line treatment of elderly patients with metastatic breast cancer.

scientific article published on August 2010

MELANOMA ADJUVANT TREATMENT: current insight and clinical features

scientific article

MUC2 but not MUC5 expression correlates with prognosis in radically resected pancreatic cancer patients

scientific article published on 01 June 2009

Management of pain in elderly patients receiving infusion of zoledronic acid for bone metastasis: a single-institution report.

scientific article published on 14 August 2007

Measurement of Autophagy by Flow Cytometry.

scientific article published in January 2017

Mechanisms of disease: Preclinical reports of antineoplastic synergistic action of bisphosphonates

scientific article

Mediastinal images resembling thymus following 131-I treatment for thyroid cancer.

scientific article

Medical treatment of orthotopic glioblastoma with transferrin-conjugated nanoparticles encapsulating zoledronic acid

scientific article

Metabolic syndrome, endocrine disruptors and prostate cancer associations: biochemical and pathophysiological evidences

scientific article

Metronomic administration of zoledronic acid and taxotere combination in castration resistant prostate cancer patients: phase I ZANTE trial

scientific article published on 8 September 2010

Mi-RNA-888-5p Is Involved in S-Adenosylmethionine Antitumor Effects in Laryngeal Squamous Cancer Cells

scientific article published on 07 December 2020

MicroRNA-125a-5p Is a Downstream Effector of Sorafenib in Its Antiproliferative Activity Toward Human Hepatocellular Carcinoma Cells

scientific article published on 16 December 2016

MicroRNA-423-5p Promotes Autophagy in Cancer Cells and Is Increased in Serum From Hepatocarcinoma Patients Treated With Sorafenib.

scientific article published on 17 March 2015

Micrornas in prostate cancer: an overview

scientific article

Mir-34: a new weapon against cancer?

scientific article published on 23 September 2014

Modified Glasgow Prognostic Score is Associated With Risk of Recurrence in Bladder Cancer Patients After Radical Cystectomy: A Multicenter Experience

scientific article

Modulation of molecular mechanisms involved in protein synthesis machinery as a new tool for the control of cell proliferation.

scientific article

Molecular dynamics simulation and automated docking of the pro-apoptotic Bax protein and its complex with a peptide designed from the Bax-binding domain of anti-apoptotic Ku70

scientific article published on 01 September 2006

Molecular targets and oxidative stress biomarkers in hepatocellular carcinoma: an overview

scientific article published on 10 October 2011

Molecular targets for the treatment of multiple myeloma.

scientific article published on September 2012

Molecular technology and the recombinant TSH have changed diagnostics of thyroid carcinoma with positive I-131 whole body scan but low serum thyroglobulin

scientific article published on 01 June 2004

Mouse Models as a Translational Platform for the Development of New Therapeutic Agents in Multiple Myeloma ⬇️

scientific article published on September 1, 2012

Multiple-target drugs: inhibitors of heat shock protein 90 and of histone deacetylase.

scientific article

Myrtucommulone production by a strain of Neofusicoccum australe endophytic in myrtle (Myrtus communis).

scientific article published on 17 October 2013

Nanocarriers Conjugated with Cell Penetrating Peptides: New Trojan Horses by Modern Ulysses

scientific article published on 15 April 2016

Nanoparticles for the delivery of zoledronic acid to prostate cancer cells: a comparative analysis through time lapse video-microscopy technique

scientific article

Nanotech revolution for the anti-cancer drug delivery through blood-brain barrier.

scientific article published on March 2012

Nanotechnological and biotechnological strategies for drug delivery

scientific article published on 01 January 2012

Nanotechnologies in cancer

scientific article published on 13 May 2013

Nanotechnologies to use bisphosphonates as potent anticancer agents: the effects of zoledronic acid encapsulated into liposomes

scientific article published on 29 March 2011

Nanotechnologies to use zoledronic acid as a potent antitumoral agent

Nanotechnologies: A Strategy to Overcome Blood-Brain Barrier ⬇️

scientific article published on January 1, 2012

Naturally occurring anti-cancer agents targeting EZH2.

scientific article published on 17 March 2017

New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Dependent Cancer

scientific article

New pharmacokinetic and pharmacodynamic tools for interferon-alpha (IFN-alpha) treatment of human cancer.

scientific article

New self-assembly nanoparticles and stealth liposomes for the delivery of zoledronic acid: a comparative study

scientific article

Non Coding RNAs: A New Avenue for the Self-Tailoring of Blood Cancer Treatment.

scientific article

Non-coding RNAs as a new dawn in tumor diagnosis.

scientific article

Non-thermal effects of electromagnetic fields at mobile phone frequency on the refolding of an intracellular protein: myoglobin.

scientific article published in September 2004

Once-per-cycle pegfilgrastim in breast cancer patients treated with docetaxel/epidoxorubicin/cyclophosphamide.

scientific article published on 22 June 2009

Optimal Management of Prostate Cancer Based on its Natural Clinical History.

scientific article published on 8 February 2017

Optimizing treatment of metastatic colorectal cancer patients with anti-EGFR antibodies: overcoming the mechanisms of cancer cell resistance.

scientific article published on 03 January 2013

Oxidative stress and ERK1/2 phosphorylation as predictors of outcome in hepatocellular carcinoma patients treated with sorafenib plus octreotide LAR.

scientific article

PI3K/Akt/mTOR signaling in medullary thyroid cancer: a promising molecular target for cancer therapy

scientific article published on 13 August 2014

Panitumumab: a new frontier of target therapy for the treatment of metastatic colorectal cancer

scientific article published on April 2010

Panobinostat synergizes with zoledronic acid in prostate cancer and multiple myeloma models by increasing ROS and modulating mevalonate and p38-MAPK pathways.

scientific article published on 24 October 2013

Pegylated liposomal doxorubicin in the management of ovarian cancer: a systematic review and metaanalysis of randomized trials

scientific article

Pembrolizumab: the value of PDL1 biomarker in head and neck cancer

scientific article published on 13 July 2016

Percutaneous ethanol injection efficacy in the treatment of large symptomatic thyroid cystic nodules: ten-year follow-up of a large series.

scientific article published on September 2002

Percutaneous ethanol injection of autonomous thyroid nodules with a volume larger than 40 ml: three years of follow-up.

scientific article

Pharmacological inhibition of HSP90 and ras activity as a new strategy in the treatment of HNSCC.

scientific article published on January 2013

Pharmacological modulation of peptide growth factor receptor expression on tumor cells as a basis for cancer therapy

scientific article published on 01 August 1994

Phase 2 trial of temozolomide using protracted low-dose and whole-brain radiotherapy for nonsmall cell lung cancer and breast cancer patients with brain metastases.

scientific article

Phase II studies of anticancer chemotherapy: indirect evidence of poor quality

scientific article published on 27 October 2006

Phase II study of sequential hormonal therapy with anastrozole/exemestane in advanced and metastatic breast cancer

scientific article published on 5 September 2005

Phase II study of temozolomide plus pegylated liposomal doxorubicin in the treatment of brain metastases from solid tumours

scientific article

Phase II trial of bevacizumab and dose/dense chemotherapy with cisplatin and metronomic daily oral etoposide in advanced non-small-cell-lung cancer patients

scientific article

Phorbol 12-myristate 13-acetate induces resistance of human melanoma cells to natural-killer- and lymphokine-activated-killer-mediated cytotoxicity

scientific article published in January 1992

Polydatin, a natural precursor of resveratrol, induces cell cycle arrest and differentiation of human colorectal Caco-2 cell.

scientific article published on 20 October 2013

Possible antioxidant role of SPA therapy with chlorine-sulphur-bicarbonate mineral water.

scientific article

Potential role of type I interferons in the treatment of pituitary adenomas.

scientific article published on 06 July 2008

Predicting efficacy and toxicity in the era of targeted therapy: focus on anti-EGFR and anti-VEGF molecules.

scientific article

Prognostic role of bcl-xL and p53 in childhood acute lymphoblastic leukemia (ALL).

scientific article

Prognostic role of translocator protein and oxidative stress markers in chronic lymphocytic leukemia patients treated with bendamustine plus rituximab

scientific article

Protective Effect of Tyrosol and S-Adenosylmethionine against Ethanol-Induced Oxidative Stress of Hepg2 Cells Involves Sirtuin 1, P53 and Erk1/2 Signaling.

scientific article

Protein kinase A as a biological target in cancer therapy

scientific article published on 01 January 2009

Protein-polyamine conjugation by transglutaminase in cancer cell differentiation: review article.

scientific article published on 26 April 2004

Protracted low dose of oral vinorelbine and temozolomide with whole-brain radiotherapy in the treatment for breast cancer patients with brain metastases

scientific article published on 14 August 2012

Pyk2 and Cyr61 at the cross-road of cAMP-dependent signalling in invasiveness and neuroendocrine differentiation of prostate cancer

scientific article published on 11 February 2009

R115777 (Zarnestra)/Zoledronic acid (Zometa) cooperation on inhibition of prostate cancer proliferation is paralleled by Erk/Akt inactivation and reduced Bcl-2 and bad phosphorylation

scientific article published on May 2007

Radiotherapy prolongs the survival of advanced non-small-cell lung cancer patients undergone to an immune-modulating treatment with dose-fractioned cisplatin and metronomic etoposide and bevacizumab (mPEBev).

scientific article published on 24 August 2017

Raf kinases mediate the phosphorylation of eukaryotic translation elongation factor 1A and regulate its stability in eukaryotic cells.

scientific article published in March 2012

Randomized phase III trial on gemcitabine versus mytomicin in recurrent superficial bladder cancer: evaluation of efficacy and tolerance

scientific article published on 19 October 2009

Regulatory T Cells and Their Prognostic Relevance in Hematologic Malignancies

scientific article published on 21 December 2017

Repeated intermittent low-dose therapy with zoledronic acid induces an early, sustained, and long-lasting decrease of peripheral vascular endothelial growth factor levels in cancer patients

scientific article

Reprogramming Tumor-Immune Cell Interface in Solid and Hematological Malignancies to Enhance Response to Therapy.

scientific article published on 5 March 2018

Role of DNA repair machinery and p53 in the testicular germ cell cancer: a review

scientific article

Role of gemcitabine-based combination therapy in the management of advanced pancreatic cancer: a meta-analysis of randomised trials

scientific article

Role of perineural invasion as a prognostic factor in laryngeal cancer

scientific article published on 24 February 2016

Role of the FAD-dependent polyamine oxidase in the selective formation of N(1),N(8)-bis(gamma-glutamyl)spermidine protein cross-links(1)

scientific article published on 01 April 2007

S-Adenosylmethionine Inhibits Cell Growth and Migration of Triple Negative Breast Cancer Cells through Upregulating MiRNA-34c and MiRNA-449a

scientific article published on 30 December 2020

S-Adenosylmethionine regulates apoptosis and autophagy in MCF-7 breast cancer cells through the modulation of specific microRNAs

scientific article published on 04 December 2018

S-Adenosylmethionine-mediated apoptosis is potentiated by autophagy inhibition induced by chloroquine in human breast cancer cells.

scientific article

Salivary microRNAs as new molecular markers in cleft lip and palate: a new frontier in molecular medicine.

scientific article

Screening for hypothyroidism in older hospitalized patients with anemia: a new insight into an old disease

scientific article published in September 2010

Second-line treatment of non small cell lung cancer by biweekly gemcitabine and docetaxel +/- granulocyte-macrophage colony stimulating factor and low dose aldesleukine.

scientific article published on 15 March 2009

Self-assembling nanoparticles encapsulating zoledronic acid inhibit mesenchymal stromal cells differentiation, migration and secretion of proangiogenic factors and their interactions with prostate cancer cells.

scientific article published on 19 April 2017

Self-assembling nanoparticles encapsulating zoledronic acid revert multidrug resistance in cancer cells

scientific article published on 9 September 2015

Self-assembly nanoparticles for the delivery of bisphosphonates into tumors

scientific article published on 3 November 2010

Serum oxidative stress markers and lipidomic profile to detect NASH patients responsive to an antioxidant treatment: a pilot study

scientific article

Short-term diet and moderate exercise in young overweight men modulate cardiocyte and hepatocarcinoma survival by oxidative stress.

scientific article

Single nucleotide polymorphisms of ABCC5 and ABCG1 transporter genes correlate to irinotecan-associated gastrointestinal toxicity in colorectal cancer patients: a DMET microarray profiling study

scientific article

Slow release lanreotide in combination with interferon-alpha2b in the treatment of symptomatic advanced medullary thyroid carcinoma

scientific article published in March 2000

Small tumor of the medial breast presenting with a contralateral lymph node involvement detected on positron emission tomography scan.

scientific article published in September 2007

Somatostatin analogues, a series of tissue transglutaminase inducers, as a new tool for therapy of mesenchimal tumors of the gastrointestinal tract

scientific article published on 06 February 2007

Sorafenib plus octreotide is an effective and safe treatment in advanced hepatocellular carcinoma: multicenter phase II So.LAR. study

scientific article published on 30 December 2009

Sphingosine analog fingolimod (FTY720) increases radiation sensitivity of human breast cancer cells in vitro

scientific article

Stealth liposomes encapsulating zoledronic acid: a new opportunity to treat neuropathic pain

scientific article published on 14 February 2013

Structural Characterization of Self-Assembling Hybrid Nanoparticles for Bisphosphonate Delivery in Tumors.

scientific article published on 12 February 2018

Structural and functional alterations of cellular components as revealed by electron microscopy.

scientific article published on 3 August 2013

Structural organization of the human eukaryotic initiation factor 5A precursor and its site-directed variant Lys50-->Arg

scientific article

Synergistic activity of everolimus and 5-aza-2'-deoxycytidine in medullary thyroid carcinoma cell lines.

scientific article published on 28 April 2017

Synergistic antitumor activity of epidermal growth factor receptor tyrosine kinase inhibitor gefitinib and IFN-alpha in head and neck cancer cells in vitro and in vivo

scientific article published in January 2006

Synergistic antitumour effect of raltitrexed and 5-fluorouracil plus folinic acid combination in human cancer cells

scientific article

Synergistic cytotoxic effects of inorganic phosphate and chemotherapeutic drugs on human osteosarcoma cells ⬇️

scientific article published on February 26, 2013

Synergistic inhibition of pancreatic adenocarcinoma cell growth by trichostatin A and gemcitabine.

scientific article published on 22 May 2007

Synthetic miR-34a mimics as a novel therapeutic agent for multiple myeloma: in vitro and in vivo evidence.

scientific article published on 3 October 2012

Systemic inflammatory status predict the outcome of k-RAS WT metastatic colorectal cancer patients receiving the thymidylate synthase poly-epitope-peptide anticancer vaccine.

scientific article

Target therapy of bone metastases and tumours

scientific article published on 01 November 2009

Target-based agents in neoadjuvant treatment of liver metastases from colorectal cancer: secret weapons in anti-cancer war?

scientific article published on 24 September 2009

Targeting Raf-kinase: molecular rationales and translational issues.

scientific article

Temporal bone meningioma involving the middle ear: A case report

scientific article

Testicular cancer from diagnosis to epigenetic factors

scientific article published on 18 September 2017

The 1,4 benzoquinone-featured 5-lipoxygenase inhibitor RF-Id induces apoptotic death through downregulation of IAPs in human glioblastoma cells.

scientific article published on 22 October 2016

The N-terminal 1-16 peptide derived in vivo from protein seminal vesicle protein IV modulates alpha-thrombin activity: potential clinical implications

scientific article published on October 2008

The PPAR-γ agonist troglitazone antagonizes survival pathways induced by STAT-3 in recombinant interferon-β treated pancreatic cancer cells.

scientific article

The Role of Target Therapy in the Treatment of Gastrointestinal Non Colorectal Cancers: Clinical Impact and Cost Consideration.

scientific article published on 8 February 2017

The cAMP analogs have potent anti-proliferative effects on medullary thyroid cancer cell lines.

scientific article

The eukaryotic initiation factor 5A is involved in the regulation of proliferation and apoptosis induced by interferon-alpha and EGF in human cancer cells

scientific article published in June 2003

The evolving role of monoclonal antibodies in the treatment of patients with advanced renal cell carcinoma: a systematic review.

scientific article

The farnesyl transferase inhibitor R115777 (Zarnestra) synergistically enhances growth inhibition and apoptosis induced on epidermoid cancer cells by Zoledronic acid (Zometa) and Pamidronate

scientific article

The farnesyltransferase inhibitor R115777 (ZARNESTRA) enhances the pro-apoptotic activity of interferon-alpha through the inhibition of multiple survival pathways

scientific article

The methyl donor S-adenosylmethionine potentiates doxorubicin effects on apoptosis of hormone-dependent breast cancer cell lines.

scientific article

The multidrug transporter P-glycoprotein: a mediator of melanoma invasion?

scientific article

The novel role of pyrvinium in cancer therapy.

scientific article published on 13 May 2017

The oral tyrosine kinase inhibitors lapatinib and sunitinib: new opportunities for the treatment of brain metastases from breast cancer? ⬇️

scientific article published on 01 February 2011

The role of E-cadherin down-regulation in oral cancer: CDH1 gene expression and epigenetic blockage.

scientific article published on January 2014

The role of eukaryotic initiation factor 5A in the control of cell proliferation and apoptosis.

scientific article

The role of somatostatin receptors in the medical treatment of acromegaly.

scientific article published on February 2004

The role of tissue microarray in the era of target-based agents.

scientific article published on June 2011

The route to solve the interplay between inflammation, angiogenesis and anti-cancer immune response.

scientific article published on 21 July 2016

The serine protease HtrA1 specifically interacts and degrades the tuberous sclerosis complex 2 protein

scientific article published on 29 July 2010

The strange connection between epidermal growth factor receptor tyrosine kinase inhibitors and dapsone: from rash mitigation to the increase in anti-tumor activity

scientific article

The stress hormone norepinephrine increases migration of prostate cancer cells in vitro and in vivo

scientific article published on 8 June 2015

The synergistic effect of everolimus and chloroquine on endothelial cell number reduction is paralleled by increased apoptosis and reduced autophagy occurrence

scientific article (publication date: 2013)

The translation elongation factor 1A in tumorigenesis, signal transduction and apoptosis: review article.

scientific article published on 26 April 2004

Theophylline administration markedly reduces hepatic and pulmonary implantation of B16-F10 melanoma cells in mice.

scientific article published in October 2000

Theophylline-induced apoptosis is paralleled by protein kinase A-dependent tissue transglutaminase activation in cancer cells

scientific article published in July 2002

Therapeutic Potential of the Natural Compound S-Adenosylmethionine as a Chemoprotective Synergistic Agent in Breast, and Head and Neck Cancer Treatment: Current Status of Research

scientific article published on 13 November 2020

Tissue transglutaminase (TG2) is involved in the resistance of cancer cells to the histone deacetylase (HDAC) inhibitor vorinostat.

scientific article

Tissue transglutaminase expression affects hypusine metabolism in BALB/c 3T3 cells.

scientific article published on October 1998

Transferrin-Targeted Nanoparticles Containing Zoledronic Acid as a Potential Tool to Inhibit Glioblastoma Growth

scientific article published on April 2016

Transferrin-conjugated SNALPs encapsulating 2'-O-methylated miR-34a for the treatment of multiple myeloma.

scientific article published on 13 February 2014

Translational and post-translational modifications of proteins as a new mechanism of action of alpha-interferon: review article.

scientific article published on 8 April 2004

Treatment of c-kit positive adenoid cystic carcinoma of the tongue: A case report

scientific article

Tumor infiltrating T lymphocytes expressing FoxP3, CCR7 or PD-1 predict the outcome of prostate cancer patients subjected to salvage radiotherapy after biochemical relapse

scientific article published on 28 October 2016

Tumour cell resistance to non-MHC-restricted lymphocytes: molecular mechanisms and clinical implications

scientific article published in May 1998

Tumour-specific uptake of anti-cancer drugs: the future is here.

scientific article published on January 2012

Two Different Serum MiRNA Signatures Correlate with the Clinical Outcome and Histological Subtype in Pleural Malignant Mesothelioma Patients.

scientific article published on 11 August 2015

Two faces for Janus: recombinant human erythropoiesis-stimulating agents and cancer mortality

scientific article published on October 2009

Type I interferon-mediated pathway interacts with peroxisome proliferator activated receptor-γ (PPAR-γ): at the cross-road of pancreatic cancer cell proliferation

scientific article published on December 2013

Type I interferons: ancient peptides with still under-discovered anti-cancer properties.

scientific article published on April 2013

UCP2 inhibition induces ROS/Akt/mTOR axis: Role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism

scientific article

Ubiquitination of tissue transglutaminase is modulated by interferon alpha in human lung cancer cells.

scientific article published in February 2003

Up-regulated EGF receptors undergo to rapid internalization and ubiquitin-dependent degradation in human cancer cells exposed to 8-Cl-cAMP

scientific article published on 01 March 1999

Urotensin II receptor determines prognosis of bladder cancer regulating cell motility/invasion

scientific article

Urotensin II receptor on preoperative biopsy is associated with upstaging and upgrading in prostate cancer

scientific article published on 18 September 2015

Urotensin II receptor predicts the clinical outcome of prostate cancer patients and is involved in the regulation of motility of prostate adenocarcinoma cells.

scientific article

Urotensin-II Receptor: A Double Identity Receptor Involved in Vasoconstriction and in the Development of Digestive Tract Cancers and other Tumors.

scientific article published on 20 June 2016

Urotensin-II receptor is over-expressed in colon cancer cell lines and in colon carcinoma in humans.

scientific article published on 22 January 2014

Vascular-homing peptides for targeted drug delivery and molecular imaging: meeting the clinical challenges

scientific article

W7FW14F apomyoglobin amyloid aggregates-mediated apoptosis is due to oxidative stress and AKT inactivation caused by Ras and Rac.

scientific article

Weekly oxaliplatin, 5-fluorouracil and folinic acid (OXALF) as first-line chemotherapy for elderly patients with advanced gastric cancer: results of a phase II trial

scientific article

Zoledronic acid affects the cytotoxic effects of Chlamydia pneumoniae and the modulation of cytokine production in human osteosarcoma cells

scientific article published on 24 June 2014

Zoledronic acid in the treatment of bone metastases by hepatocellular carcinoma: a case series

scientific article published on 16 September 2009

Zoledronic acid induces antiproliferative and apoptotic effects in human pancreatic cancer cells in vitro.

scientific article published on June 2003

Zoledronic acid-encapsulating self-assembling nanoparticles and doxorubicin: a combinatorial approach to overcome simultaneously chemoresistance and immunoresistance in breast tumors

scientific article published on 09 March 2016

alpha-Interferon potentiates epidermal growth factor receptor-mediated effects on human epidermoid carcinoma KB cells

scientific article published on 01 May 1995

eIF5A isoforms and cancer: two brothers for two functions?

scientific article

miR-29b negatively regulates human osteoclastic cell differentiation and function: implications for the treatment of multiple myeloma-related bone disease

scientific article published on July 2013

miR-29b sensitizes multiple myeloma cells to bortezomib-induced apoptosis through the activation of a feedback loop with the transcription factor Sp1

scientific article published on 29 November 2012

pEGFR-Tyr 845 expression as prognostic factors in oral squamous cell carcinoma: a tissue-microarray study with clinic-pathological correlations

scientific article

β2-AR blockade potentiates MEK1/2 inhibitor effect on HNSCC by regulating the Nrf2-mediated defense mechanism

scientific article published on 13 October 2020

γ-Tocopherol inhibits human prostate cancer cell proliferation by up-regulation of transglutaminase 2 and down-regulation of cyclins.

scientific article

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