List of works by Thorsten Heinekamp

A Nonredundant Phosphopantetheinyl Transferase, PptA, Is a Novel Antifungal Target That Directs Secondary Metabolite, Siderophore, and Lysine Biosynthesis in Aspergillus fumigatus and Is Critical for Pathogenicity.

scientific article

A dedicated glutathione S-transferase mediates carbon-sulfur bond formation in gliotoxin biosynthesis

scientific article published on 22 July 2011

Activity and Safety of Inhaled Itraconazole Nanosuspension in a Model Pulmonary Aspergillus fumigatus Infection in Inoculated Young Quails

scientific article published on 20 March 2015

An Iterative O-Methyltransferase Catalyzes 1,11-Dimethylation of Aspergillus fumigatus Fumaric Acid Amides.

scientific article published on 21 July 2016

Analysis of mating-dependent transcription of Blakeslea trispora carotenoid biosynthesis genes carB and carRA by quantitative real-time PCR.

scientific article published on 3 March 2005

Aspergillus fumigatus melanins: interference with the host endocytosis pathway and impact on virulence.

scientific article published on January 2012

BZI-1 specifically heterodimerises with the tobacco bZIP transcription factors BZI-2, BZI-3/TBZF and BZI-4, and is functionally involved in flower development.

scientific article published in November 2001

Biosynthesis and function of gliotoxin in Aspergillus fumigatus

scientific article

CRISPR-Cas9-Based Discovery of the Verrucosidin Biosynthesis Gene Cluster in Penicillium polonicum ⬇️

scientific article published on 21 May 2021

Characterisation of the laccase-encoding gene abr2 of the dihydroxynaphthalene-like melanin gene cluster of Aspergillus fumigatus

scientific article published on 19 September 2006

Characterization of the Aspergillus fumigatus detoxification systems for reactive nitrogen intermediates and their impact on virulence

scientific article

Conidial Dihydroxynaphthalene Melanin of the Human Pathogenic Fungus Aspergillus fumigatus Interferes with the Host Endocytosis Pathway

scientific article published on 3 May 2011

Deletion of the gliP gene of Aspergillus fumigatus results in loss of gliotoxin production but has no effect on virulence of the fungus in a low-dose mouse infection model

scientific article published on 31 August 2006

Discovery of fungal surface NADases predominantly present in pathogenic species

scientific article published on 12 March 2021

Epidithiodiketopiperazine biosynthesis: a four-enzyme cascade converts glutathione conjugates into transannular disulfide bridges

scientific article published on 26 August 2013

Epidithiol formation by an unprecedented twin carbon-sulfur lyase in the gliotoxin pathway

scientific article

Flavoenzyme-catalyzed formation of disulfide bonds in natural products

scientific article

Flotillin-Dependent Membrane Microdomains Are Required for Functional Phagolysosomes against Fungal Infections

scientific article published on 01 August 2020

Functional characterization of the Aspergillus fumigatus calcineurin

scientific article published on 20 September 2006

Genetic engineering activates biosynthesis of aromatic fumaric acid amides in the human pathogen Aspergillus fumigatus

scientific article published on 19 December 2014

Gliotoxin from Aspergillus fumigatus Abrogates Leukotriene B4 Formation through Inhibition of Leukotriene A4 Hydrolase

scientific article published on 07 February 2019

HapX-mediated adaption to iron starvation is crucial for virulence of Aspergillus fumigatus

scientific article

Heptahelical receptors GprC and GprD of Aspergillus fumigatus Are essential regulators of colony growth, hyphal morphogenesis, and virulence

scientific article

High-Throughput Gene Replacement in Aspergillus fumigatus

scientific article published on 01 September 2019

Homo- and heterodimers of tobacco bZIP proteins counteract as positive or negative regulators of transcription during pollen development

scientific article published on 16 April 2010

Human and plant fungal pathogens: the role of secondary metabolites

scientific article published on 30 January 2014

Identification of Aspergillus fumigatus Surface Components That Mediate Interaction of Conidia and Hyphae With Human Platelets

scientific article

Interference of Aspergillus fumigatus with the immune response

scientific article

Melanin dependent survival of Apergillus fumigatus conidia in lung epithelial cells

scientific article published on 26 April 2014

Mitogen-Activated Protein Kinase Cross-Talk Interaction Modulates the Production of Melanins in Aspergillus fumigatus

scientific article published on 26 March 2019

Molecular characterization of the Aspergillus fumigatus NCS-1 homologue, NcsA.

scientific article

Opposed effects of enzymatic gliotoxin N- and S-methylations

scientific article published on 7 August 2014

Production of pyomelanin, a second type of melanin, via the tyrosine degradation pathway in Aspergillus fumigatus

scientific article published on 21 November 2008

Protein kinase A regulates growth, sporulation, and pigment formation in Aspergillus fumigatus

scientific article published on 6 June 2008

Proteome Analysis Reveals the Conidial Surface Protein CcpA Essential for Virulence of the Pathogenic Fungus

article

Proteomics of Aspergillus fumigatus conidia-containing phagolysosomes identifies processes governing immune evasion.

scientific article

Pyomelanin formation in Aspergillus fumigatus requires HmgX and the transcriptional activator HmgR but is dispensable for virulence

scientific article

Reconstitution of Enzymatic Carbon–Sulfur Bond Formation Reveals Detoxification-Like Strategy in Fungal Toxin Biosynthesis

scientific article published on 17 August 2018

Regio- and Stereoselective Oxidative Phenol Coupling inAspergillus niger

scientific article published on 03 September 2012

SCF Ubiquitin Ligase F-box Protein Fbx15 Controls Nuclear Co-repressor Localization, Stress Response and Virulence of the Human Pathogen Aspergillus fumigatus

scientific article

Secretome analysis of Aspergillus fumigatus reveals Asp-hemolysin as a major secreted protein

scientific article

SreA-mediated iron regulation in Aspergillus fumigatus

scientific article (publication date: October 2008)

Systems biology of fungal infection.

scientific article published on 2 April 2012

The 2008 update of the Aspergillus nidulans genome annotation: a community effort

scientific article

The Aspergillus fumigatus conidial melanin production is regulated by the bifunctional bHLH DevR and MADS-box RlmA transcription factors

scientific article published on 9 July 2016

The Crystal Structure of Peroxiredoxin Asp f3 Provides Mechanistic Insight into Oxidative Stress Resistance and Virulence of Aspergillus fumigatus

scientific article published on 14 September 2016

The MAP kinase MpkA controls cell wall integrity, oxidative stress response, gliotoxin production and iron adaptation in Aspergillus fumigatus

scientific article published on 30 August 2011

The MpkA MAP kinase module regulates cell wall integrity signaling and pyomelanin formation in Aspergillus fumigatus.

scientific article published on 26 August 2009

The Pheromone Module SteC-MkkB-MpkB-SteD-HamE Regulates Development, Stress Responses and Secondary Metabolism in Aspergillus fumigatus

scientific article published on 07 May 2020

The Zn2Cys6-type transcription factor LeuB cross-links regulation of leucine biosynthesis and iron acquisition in Aspergillus fumigatus

scientific article published on 26 October 2018

The akuB(KU80) mutant deficient for nonhomologous end joining is a powerful tool for analyzing pathogenicity in Aspergillus fumigatus

scientific article

The alpha-helical D1 domain of the tobacco bZIP transcription factor BZI-1 interacts with the ankyrin-repeat protein ANK1 and is important for BZI-1 function, both in auxin signaling and pathogen response

scientific article

The hypoxia-induced dehydrogenase HorA is required for coenzyme Q10 biosynthesis, azole sensitivity and virulence of Aspergillus fumigatus

scientific article published on 17 March 2016

The mitogen-activated protein kinase MpkA of Aspergillus fumigatus regulates cell wall signaling and oxidative stress response

scientific article published on 25 September 2007

The novel globin protein fungoglobin is involved in low oxygen adaptation of Aspergillus fumigatus

scientific article published on 7 July 2014

The tobacco bZIP transcription factor BZI-1 binds the GH3 promoter in vivo and modulates auxin-induced transcription

scientific article published in April 2004

The tobacco bZIP transcription factor BZI-1 binds to G-box elements in the promoters of phenylpropanoid pathway genes in vitro, but it is not involved in their regulation in vivo.

scientific article

Towards Raman spectroscopy of urine as screening tool

scientific article published on 19 November 2019

Transannular disulfide formation in gliotoxin biosynthesis and its role in self-resistance of the human pathogen Aspergillus fumigatus

scientific article published in July 2010

Transcription Factor SomA Is Required for Adhesion, Development and Virulence of the Human Pathogen Aspergillus fumigatus

scientific article published on 3 November 2015

Transcriptome analysis of cyclic AMP-dependent protein kinase A-regulated genes reveals the production of the novel natural compound fumipyrrole by Aspergillus fumigatus

scientific article published on 11 March 2015

Virulence determinants of the human pathogenic fungus Aspergillus fumigatus protect against soil amoeba predation

scientific article published on 12 February 2015

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