List of works - Yorgo Modis

A bioactive phlebovirus-like envelope protein in a hookworm endogenous virus

scientific article published on 11 May 2022

A biosynthetic thiolase in complex with a reaction intermediate: the crystal structure provides new insights into the catalytic mechanism

scientific article

A graph theoretic approach to utilizing protein structure to identify non-random somatic mutations.

scientific article

A ligand-binding pocket in the dengue virus envelope glycoprotein

scientific article

A novel membrane fusion protein family in Flaviviridae?

scientific article published on 23 February 2014

A spatial simulation approach to account for protein structure when identifying non-random somatic mutations

scientific article

A type III complement factor D deficiency: Structural insights for inhibition of the alternative pathway ⬇️

scientific article published on 6 March 2018

An Inheritable variant of the innate immune receptor melanoma differentiation-associated gene 5 promotes clearance of hepatitis C virus

scientific article published on 5 January 2015

Ancylostoma ceylanicum Excretory–Secretory Protein 2 Adopts a Netrin-Like Fold and Defines a Novel Family of Nematode Proteins

scientific article

Atomic model of the papillomavirus capsid

scientific article

Chitinase 3-like 1 Regulates Cellular and Tissue Responses via IL-13 Receptor α2

Chitinase 3-like 1 regulates cellular and tissue responses via IL-13 receptor α2

scientific article published on 22 August 2013

Class II fusion proteins

scientific article published on January 2013

Correction: Selective Pressure Causes an RNA Virus to Trade Reproductive Fitness for Increased Structural and Thermal Stability of a Viral Enzyme

article

Corrigendum: IL-13Rα2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses

scientific article published on 14 November 2016

Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis

CryoEM structures of MDA5-dsRNA filaments at different stages of ATP hydrolysis

Crystal Structure of Dengue Virus Type 1 Envelope Protein in the Postfusion Conformation and Its Implications for Membrane Fusion

scientific article (publication date: May 2009)

Crystal Structure of Glycoprotein C from a Hantavirus in the Post-fusion Conformation.

scientific article

Crystal Structure of West Nile Virus Envelope Glycoprotein Reveals Viral Surface Epitopes

scientific article (publication date: November 2006)

Crystal Structure of an Insect Antifreeze Protein and Its Implications for Ice Binding

scientific article

Crystal structure of glycoprotein C from Rift Valley fever virus

scientific article

Crystal structure of glycoprotein E2 from bovine viral diarrhea virus

scientific article

Crystal structure of the dimeric coiled-coil domain of the cytosolic nucleic acid sensor LRRFIP1

scientific article

Crystallization and X-ray diffraction analysis of peroxisomal Δ3-Δ2-enoyl-CoA isomerase fromSaccharomyces cerevisiae

scientific article published on 01 August 2000

Crystallographic analysis of the reaction pathway of Zoogloea ramigera biosynthetic thiolase

scientific article

DNA binding to proteolytically activated TLR9 is sequence-independent and enhanced by DNA curvature

scientific article

Data publication with the structural biology data grid supports live analysis

scientific article

Disassembly and reassembly of human papillomavirus virus-like particles produces more virion-like antibody reactivity

scientific article

Endosomal vesicles as vehicles for viral genomes

scientific article published on 15 April 2014

Exploiting structural biology in the fight against parasitic diseases ⬇️

scientific article published on February 15, 2012

Exploiting subtle structural differences in heavy-atom derivatives for experimental phasing.

scientific article

FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle

scientific article published on 01 January 2020

Flunarizine arrests hepatitis C virus membrane fusion.

scientific article

Functional assessment and structural basis of antibody binding to human papillomavirus capsid

scientific article published on 17 December 2015

How influenza virus is locked out of the cell

scholarly article

Human interleukin-2 receptor β mutations associated with defects in immunity and peripheral tolerance

scientific article published on 30 April 2019

Hyperactivation of HUSH complex function by Charcot-Marie-Tooth disease mutation in MORC2.

scientific article published on 05 June 2017

IL-13Rα2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses

scientific article published on 15 September 2016

Leveraging protein quaternary structure to identify oncogenic driver mutations

scientific article

MAVS polymers smaller than 80 nm induce mitochondrial membrane remodeling and interferon signaling

scientific article published on 16 February 2019

MDA5 assembles into a polar helical filament on dsRNA.

scientific article

MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA

scientific article

Molecular Mechanisms of Flaviviral Membrane Fusion

article published in 2009

N-Glycosylation at the SynCAM (Synaptic Cell Adhesion Molecule) Immunoglobulin Interface Modulates Synaptic Adhesion

scientific article

Neuropathic MORC2 mutations perturb GHKL ATPase dimerization dynamics and epigenetic silencing by multiple structural mechanisms

scientific article published on 13 February 2018

Neuropathic mutations in MORC2 perturb GHKL ATPase dimerization dynamics and epigenetic silencing by multiple structural mechanisms

P(I) Release Limits the Intrinsic and RNA-Stimulated ATPase Cycles of DEAD-Box Protein 5 (Dbp5)

scientific article published on 27 December 2015

Pattern Recognition and Signaling Mechanisms of RIG-I and MDA5

scientific article published on 23 July 2014

Peroxiredoxin-1 from the Human Hookworm Ancylostoma ceylanicum Forms a Stable Oxidized Decamer and Is Covalently Inhibited by Conoidin A

scientific article

Physico-chemical requirements and kinetics of membrane fusion of flavivirus-like particles.

scientific article

Protein crystallization for X-ray crystallography

scientific article

Quantification of the affinities and kinetics of protein interactions using silicon nanowire biosensors

scientific article

RNA:DNA hybrids are a novel molecular pattern sensed by TLR9.

scientific article published on 10 February 2014

Relating structure to evolution in class II viral membrane fusion proteins

scientific article published on 11 February 2014

SRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition

scientific article published on May 2015

Selective pressure causes an RNA virus to trade reproductive fitness for increased structural and thermal stability of a viral enzyme

scientific article

Structural basis of innate immune recognition of viral RNA.

scientific article

Structural models of the membrane anchors of envelope glycoproteins E1 and E2 from pestiviruses

scientific article published on 25 February 2014

Structural studies of viperin, an antiviral radical SAM enzyme

scientific article

Structure and functional mapping of the KRAB‐KAP1 repressor complex

scientific article published in 2022

Structure of KAP1 tripartite motif identifies molecular interfaces required for retroelement silencing

scientific article published on 09 July 2019

Structure of the dengue virus envelope protein after membrane fusion

scientific article

Structure-Based Analysis of Toxoplasma gondii Profilin: A Parasite-Specific Motif Is Required for Recognition by Toll-Like Receptor 11

scientific article

TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control

scientific article published on 02 October 2020

The 1.8 A crystal structure of the dimeric peroxisomal 3-ketoacyl-CoA thiolase of Saccharomyces cerevisiae: implications for substrate binding and reaction mechanism

scientific article

The crystal structure of dienoyl-CoA isomerase at 1.5 A resolution reveals the importance of aspartate and glutamate sidechains for catalysis

scientific article

The mu2 subunit of the clathrin adaptor AP-2 binds to FDNPVY and YppØ sorting signals at distinct sites

scientific article

Toll-like receptor 5 forms asymmetric dimers in the absence of flagellin

scientific article

Two crystal structures of N-acetyltransferases reveal a new fold for CoA-dependent enzymes

scientific article published on 01 November 1998

Utilizing protein structure to identify non-random somatic mutations

scientific article

Variable surface epitopes in the crystal structure of dengue virus type 3 envelope glycoprotein

scientific article (publication date: 2005)

Viral membrane fusion and nucleocapsid delivery into the cytoplasm are distinct events in some flaviviruses

scientific article (publication date: 2013)

Virus-like particle-based human vaccines: quality assessment based on structural and functional properties

scientific article published on 11 October 2013

West Nile virus envelope protein inhibits dsRNA-induced innate immune responses

scientific article published in December 2007

X-ray structure of a protein-conducting channel

scientific article

List of works by Yorgo Modis

A bioactive phlebovirus-like envelope protein in a hookworm endogenous virus

A biosynthetic thiolase in complex with a reaction intermediate: the crystal structure provides new insights into the catalytic mechanism

A graph theoretic approach to utilizing protein structure to identify non-random somatic mutations.

A ligand-binding pocket in the dengue virus envelope glycoprotein

A novel membrane fusion protein family in Flaviviridae?

A spatial simulation approach to account for protein structure when identifying non-random somatic mutations

A type III complement factor D deficiency: Structural insights for inhibition of the alternative pathway ⬇️

An Inheritable variant of the innate immune receptor melanoma differentiation-associated gene 5 promotes clearance of hepatitis C virus

Ancylostoma ceylanicum Excretory–Secretory Protein 2 Adopts a Netrin-Like Fold and Defines a Novel Family of Nematode Proteins

Atomic model of the papillomavirus capsid

Chitinase 3-like 1 Regulates Cellular and Tissue Responses via IL-13 Receptor α2

Chitinase 3-like 1 Regulates Cellular and Tissue Responses via IL-13 Receptor α2

Chitinase 3-like 1 regulates cellular and tissue responses via IL-13 receptor α2

Class II fusion proteins

Correction: Selective Pressure Causes an RNA Virus to Trade Reproductive Fitness for Increased Structural and Thermal Stability of a Viral Enzyme

Corrigendum: IL-13Rα2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses

Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis

CryoEM structures of MDA5-dsRNA filaments at different stages of ATP hydrolysis

Crystal Structure of Dengue Virus Type 1 Envelope Protein in the Postfusion Conformation and Its Implications for Membrane Fusion

Crystal Structure of Glycoprotein C from a Hantavirus in the Post-fusion Conformation.

Crystal Structure of West Nile Virus Envelope Glycoprotein Reveals Viral Surface Epitopes

Crystal Structure of an Insect Antifreeze Protein and Its Implications for Ice Binding

Crystal structure of glycoprotein C from Rift Valley fever virus

Crystal structure of glycoprotein E2 from bovine viral diarrhea virus

Crystal structure of the dimeric coiled-coil domain of the cytosolic nucleic acid sensor LRRFIP1

Crystallization and X-ray diffraction analysis of peroxisomal Δ3-Δ2-enoyl-CoA isomerase fromSaccharomyces cerevisiae

Crystallographic analysis of the reaction pathway of Zoogloea ramigera biosynthetic thiolase

DNA binding to proteolytically activated TLR9 is sequence-independent and enhanced by DNA curvature

Data publication with the structural biology data grid supports live analysis

Disassembly and reassembly of human papillomavirus virus-like particles produces more virion-like antibody reactivity

Endosomal vesicles as vehicles for viral genomes

Exploiting structural biology in the fight against parasitic diseases ⬇️

Exploiting subtle structural differences in heavy-atom derivatives for experimental phasing.

FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle

Flunarizine arrests hepatitis C virus membrane fusion.

Functional assessment and structural basis of antibody binding to human papillomavirus capsid

How influenza virus is locked out of the cell

Human interleukin-2 receptor β mutations associated with defects in immunity and peripheral tolerance

Hyperactivation of HUSH complex function by Charcot-Marie-Tooth disease mutation in MORC2.

IL-13Rα2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses

Leveraging protein quaternary structure to identify oncogenic driver mutations

MAVS polymers smaller than 80 nm induce mitochondrial membrane remodeling and interferon signaling

MDA5 assembles into a polar helical filament on dsRNA.

MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA

Molecular Mechanisms of Flaviviral Membrane Fusion

N-Glycosylation at the SynCAM (Synaptic Cell Adhesion Molecule) Immunoglobulin Interface Modulates Synaptic Adhesion

Neuropathic MORC2 mutations perturb GHKL ATPase dimerization dynamics and epigenetic silencing by multiple structural mechanisms

Neuropathic mutations in MORC2 perturb GHKL ATPase dimerization dynamics and epigenetic silencing by multiple structural mechanisms

P(I) Release Limits the Intrinsic and RNA-Stimulated ATPase Cycles of DEAD-Box Protein 5 (Dbp5)

Pattern Recognition and Signaling Mechanisms of RIG-I and MDA5

Peroxiredoxin-1 from the Human Hookworm Ancylostoma ceylanicum Forms a Stable Oxidized Decamer and Is Covalently Inhibited by Conoidin A

Physico-chemical requirements and kinetics of membrane fusion of flavivirus-like particles.

Protein crystallization for X-ray crystallography

Quantification of the affinities and kinetics of protein interactions using silicon nanowire biosensors

RNA:DNA hybrids are a novel molecular pattern sensed by TLR9.

Relating structure to evolution in class II viral membrane fusion proteins

SRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition

Selective pressure causes an RNA virus to trade reproductive fitness for increased structural and thermal stability of a viral enzyme

Structural basis of innate immune recognition of viral RNA.

Structural models of the membrane anchors of envelope glycoproteins E1 and E2 from pestiviruses

Structural studies of viperin, an antiviral radical SAM enzyme

Structure and functional mapping of the KRAB‐KAP1 repressor complex

Structure of KAP1 tripartite motif identifies molecular interfaces required for retroelement silencing

Structure of the dengue virus envelope protein after membrane fusion

Structure-Based Analysis of Toxoplasma gondii Profilin: A Parasite-Specific Motif Is Required for Recognition by Toll-Like Receptor 11

TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control

The 1.8 A crystal structure of the dimeric peroxisomal 3-ketoacyl-CoA thiolase of Saccharomyces cerevisiae: implications for substrate binding and reaction mechanism

The crystal structure of dienoyl-CoA isomerase at 1.5 A resolution reveals the importance of aspartate and glutamate sidechains for catalysis

The mu2 subunit of the clathrin adaptor AP-2 binds to FDNPVY and YppØ sorting signals at distinct sites

Toll-like receptor 5 forms asymmetric dimers in the absence of flagellin

Two crystal structures of N-acetyltransferases reveal a new fold for CoA-dependent enzymes

Utilizing protein structure to identify non-random somatic mutations

Variable surface epitopes in the crystal structure of dengue virus type 3 envelope glycoprotein

Viral membrane fusion and nucleocapsid delivery into the cytoplasm are distinct events in some flaviviruses

Virus-like particle-based human vaccines: quality assessment based on structural and functional properties

West Nile virus envelope protein inhibits dsRNA-induced innate immune responses

X-ray structure of a protein-conducting channel