List of works by Mike Heilemann

3D d STORM Imaging of Fixed Brain Tissue

scientific article published on January 2017

A Reducing and Oxidizing System Minimizes Photobleaching and Blinking of Fluorescent Dyes

scientific article (publication date: 7 July 2008)

A SNAP-tagged derivative of HIV-1--a versatile tool to study virus-cell interactions

scientific article

A hydrophilic gel matrix for single-molecule super-resolution microscopy

A new photoactivatable near-infrared-emitting QCy7 fluorophore for single-molecule super-resolution microscopy.

scientific article

A set of homo-oligomeric standards allows accurate protein counting

scientific article published on 20 August 2015

A simple method to estimate the average localization precision of a single-molecule localization microscopy experiment

scientific article published on 13 February 2014

A toolbox for multiplexed super-resolution imaging of the E. coli nucleoid and membrane using novel PAINT labels

scientific article published in Scientific Reports

A two-photon activatable amino acid linker for the induction of fluorescence

scientific article published on 01 October 2015

Aligning the μs-ALEX Setup

scientific article published on 2 November 2015

Alternating Laser Excitation for Solution-Based Single-Molecule FRET.

scientific article published on 2 November 2015

Art and artifacts in single-molecule localization microscopy: beyond attractive images

scientific article published in March 2014

Assembling the μs-ALEX Setup

scientific article published on 2 November 2015

Automated highly multiplexed super-resolution imaging of protein nano-architecture in cells and tissues

scientific article published on 25 March 2020

BACE-1 is expressed in the blood-brain barrier endothelium and is upregulated in a murine model of Alzheimer's disease

scientific article published on 13 October 2015

Biased signalling is an essential feature of TLR4 in glioma cells

scientific article published on 23 September 2016

Buffer controlled photoswitching microscopy using standard organic fluorophores

scholarly article published 10 February 2011

Carbocyanine dyes as efficient reversible single-molecule optical switch

scientific article

Chemically induced photoswitching of fluorescent probes--a general concept for super-resolution microscopy.

scientific article published on 13 April 2011

Click chemistry facilitates direct labelling and super-resolution imaging of nucleic acids and proteins†Electronic supplementary information (ESI) available. See DOI: 10.1039/c4ra01027bClick here for additional data file

scientific article

Competitive Binding Study Revealing the Influence of Fluorophore Labels on Biomolecular Interactions

scientific article published on 22 October 2019

Coordinate-based co-localization-mediated analysis of arrestin clustering upon stimulation of the C-C chemokine receptor 5 with RANTES/CCL5 analogues

scientific article published on 13 March 2014

Coordinate-based colocalization analysis of single-molecule localization microscopy data

scientific article

Correlative Single-Molecule FRET and DNA-PAINT Imaging

scientific article published on 29 June 2018

Correlative light- and electron microscopy with chemical tags

scientific article published on 31 March 2014

Correlative super-resolution imaging of RNA polymerase distribution and dynamics, bacterial membrane and chromosomal structure in Escherichia coli

scientific article

DNA-Based Molecular Wires: Multiple Emission Pathways of Individual Constructs

scientific article published on 01 December 2006

DeepBacs for multi-task bacterial image analysis using open-source deep learning approaches

scientific article published in 2022

Design of molecular photonic wires based on multistep electronic excitation transfer

scientific article

Development of a molecular photonic wire by means of multiparameter single-molecule spectroscopy

Direct binding of hepatocyte growth factor and vascular endothelial growth factor to CD44v6.

scientific article

Direct stochastic optical reconstruction microscopy (dSTORM).

scientific article

Direct stochastic optical reconstruction microscopy with standard fluorescent probes

scientific article

Dissecting and reducing the heterogeneity of excited-state energy transport in DNA-based photonic wires

scientific article

Dual color photoactivation localization microscopy of cardiomyopathy-associated desmin mutants

scientific article

Editorial overview: Molecular imaging

scientific article published on 28 June 2014

Enhanced labeling density and whole-cell 3D dSTORM imaging by repetitive labeling of target proteins.

scientific article published on 3 April 2018

Expanding the host cell ubiquitylation machinery targeting cytosolic Salmonella

scientific article published on 6 August 2017

Extracting quantitative information from single-molecule super-resolution imaging data with LAMA - LocAlization Microscopy Analyzer

scientific article

Fluorescence microscopy beyond the diffraction limit

scientific article

Fluorescence of Single Molecules in Polymer Films: Sensitivity of Blinking to Local Environment

scientific article published in June 2007

Fluorescent proteins for single-molecule fluorescence applications

scientific article

Fluorescently labeled 1nm thin nanomembranes

scientific article published on 04 February 2010

Full length RTN3 regulates turnover of tubular endoplasmic reticulum via selective autophagy

scientific article

High-resolution colocalization of single dye molecules by fluorescence lifetime imaging microscopy.

scientific article

High-resolution colocalization of single molecules within the resolution gap of far-field microscopy

scientific article

Hybridization and reaction-based fluorogenic nucleic acid probes

scientific article published on 01 October 2012

Identification of the Product of Photoswitching of an Oxazine Fluorophore Using Fourier Transform Infrared Difference Spectroscopy

Imaging diffusion in living cells using time-correlated single-photon counting

scientific article published on 6 September 2007

In this special issue

scientific article published on 05 June 2014

In this special issue. In focus: Single-molecule super-resolution microscopy

scientific article published on 21 May 2014

Increasing the brightness of cyanine fluorophores for single-molecule and superresolution imaging

scientific article published on 2 December 2013

Janus nanomembranes: a generic platform for chemistry in two dimensions

scientific article published on November 2010

Kar1 binding to Sfi1 C-terminal regions anchors the SPB bridge to the nuclear envelope

scientific article published on 15 June 2015

Ligand-modulated folding of the full-length adenine riboswitch probed by NMR and single-molecule FRET spectroscopy

scientific article published on 15 February 2017

Light at the end of the tunnel

scientific article

Linear ubiquitination of cytosolic Salmonella Typhimurium activates NF-κB and restricts bacterial proliferation

scientific article

Lithium insertion mechanism in CoSb3analysed by121Sb Mössbauer spectrometry, X-ray absorption spectroscopy and electronic structure calculations

article

Live-cell labeling of endogenous proteins with nanometer precision by transduced nanobodies

scientific article published on 20 August 2018

Live-cell protein labelling with nanometre precision by cell squeezing

scientific article published on 29 January 2016

Live-cell super-resolution imaging with synthetic fluorophores

scientific article published on 30 January 2012

Live-cell super-resolution imaging with trimethoprim conjugates

scientific article published on 08 August 2010

Measuring localization performance of super-resolution algorithms on very active samples.

scientific article published in April 2011

Membrane dynamics of resting and internalin B-bound MET receptor tyrosine kinase studied by single-molecule tracking.

scientific article published on 29 August 2017

Model-independent counting of molecules in single-molecule localization microscopy

scientific article published on 27 July 2016

Molecular counting of membrane receptor subunits with single-molecule localization microscopy

Molecule Counts in Localization Microscopy with Organic Fluorophores

scientific article published on 14 February 2017

Monitoring multiple distances within a single molecule using switchable FRET

scientific article published on 05 September 2010

Multi-colour direct STORM with red emitting carbocyanines

scientific article

Multicolor photoswitching microscopy for subdiffraction-resolution fluorescence imaging

scientific article

Multiscale spatial organization of RNA polymerase in Escherichia coli

scientific article published on July 2013

Multistep Energy Transfer in Single Molecular Photonic Wires

scientific article published on 01 June 2004

Nanoscopy of bacterial cells immobilized by holographic optical tweezers

scientific article

One, two or three? Probing the stoichiometry of membrane proteins by single-molecule localization microscopy

scientific article

PCNA appears in two populations of slow and fast diffusion with a constant ratio throughout S-phase in replicating mammalian cells

scientific article published on 13 January 2016

Peptidomimetics That Inhibit and Partially Reverse the Aggregation of Aβ1-42.

scientific article published on 25 August 2017

Periodic acceptor excitation spectroscopy of single molecules.

scientific article

Photoinduced formation of reversible dye radicals and their impact on super-resolution imaging.

scientific article published on 10 December 2010

Photoswitchable fluorophores for single-molecule localization microscopy.

scientific article published on January 2013

Photoswitches: Key molecules for subdiffraction-resolution fluorescence imaging and molecular quantification

scientific article published on 24 February 2009

Photoswitching microscopy with subdiffraction-resolution

Protein-Specific, Multicolor and 3D STED Imaging in Cells with DNA-Labeled Antibodies

scientific article published on 07 November 2019

Quantitative Single-Molecule Localization Microscopy (qSMLM) of Membrane Proteins Based on Kinetic Analysis of Fluorophore Blinking Cycles.

scientific article published in January 2017

Quantitative morphological analysis of arrestin2 clustering upon G protein-coupled receptor stimulation by super-resolution microscopy

scientific article published on 30 September 2013

Quantitative single-molecule imaging of TLR4 reveals ligand-specific receptor dimerization.

scientific article

Quantitative single-molecule imaging of TNFR1 reveals zafirlukast as antagonist of TNFR1 clustering and TNFα-induced NF-ĸB signaling

scientific article published on 13 May 2020

Quantitative single-molecule localization microscopy combined with rule-based modeling reveals ligand-induced TNF-R1 reorganization toward higher-order oligomers

scientific article

Quantitative single-molecule microscopy reveals that CENP-A(Cnp1) deposition occurs during G2 in fission yeast.

scientific article published on July 2012

Quantum dot triexciton imaging with three-dimensional subdiffraction resolution

scientific article

Real-time analysis and visualization for single-molecule based super-resolution microscopy.

scientific article

Real-time computation of subdiffraction-resolution fluorescence images

scientific article

Receptor-ligand interactions: binding affinities studied by single-molecule and super-resolution microscopy on intact cells

scientific article published on 01 March 2014

Reconfigurable, braced, three-dimensional DNA nanostructures.

scientific article

Red light-triggered photoreduction on a nucleic acid template

scientific article published on 30 July 2020

SLAP: Small Labeling Pair for Single-Molecule Super-Resolution Imaging.

scientific article published on 15 July 2015

SPT and Imaging FCS Provide Complementary Information on the Dynamics of Plasma Membrane Molecules.

scientific article published on 9 April 2018

STED nanoscopy of the centrosome linker reveals a CEP68-organized, periodic rootletin network anchored to a C-Nap1 ring at centrioles

scientific article published on 20 February 2018

Sample Preparation and Data Acquisition for μs-ALEX.

scientific article

Schwann cells can be reprogrammed to multipotency by culture.

scientific article published on June 2011

Sequential Super-Resolution Imaging of Bacterial Regulatory Proteins: The Nucleoid and the Cell Membrane in Single, Fixed E. coli Cells

scientific article

Shedding new light on viruses: super-resolution microscopy for studying human immunodeficiency virus

scientific article published on 31 July 2013

Simple method for sub-diffraction resolution imaging of cellular structures on standard confocal microscopes by three-photon absorption of quantum dots

scientific article published on 21 May 2013

Single cell super-resolution imaging of E. coli OmpR during environmental stress.

scientific article published on 9 July 2015

Single-Molecule Localization Microscopy in Eukaryotes

scientific article

Single-Molecule Super-Resolution Microscopy Reveals Heteromeric Complexes of MET and EGFR upon Ligand Activation

scientific article published on 17 April 2020

Single-molecule DNA biosensors for protein and ligand detection.

scientific article published in February 2010

Single-molecule FRET analysis of protein-DNA complexes

scientific article

Single-molecule analysis reveals agonist-specific dimer formation of µ-opioid receptors

scientific article published on 15 June 2020

Single-molecule coordinate-based analysis of the morphology of HIV-1 assembly sites with near-molecular spatial resolution

scientific article published on 23 August 2012

Single-molecule imaging and quantification of the immune-variant adhesin VAR2CSA on knobs of -infected erythrocytes

scientific article published on 08 May 2019

Single-molecule imaging reveals the oligomeric state of functional TNFα-induced plasma membrane TNFR1 clusters in cells

scientific article published on 14 January 2020

Single-molecule localization microscopy-near-molecular spatial resolution in light microscopy with photoswitchable fluorophores.

scientific article published on September 2013

Single-molecule methods to study membrane receptor oligomerization.

scientific article

Single-molecule photobleaching reveals increased MET receptor dimerization upon ligand binding in intact cells

scientific article

Single-molecule super-resolution imaging by tryptophan-quenching-induced photoswitching of phalloidin-fluorophore conjugates.

scientific article published on 5 March 2014

Single-particle tracking uncovers dynamics of glutamate-induced retrograde transport of NF-κB p65 in living neurons

scientific article published on 18 May 2016

Spectrally resolved fluorescence lifetime imaging microscopy (SFLIM) and coincidence analysis: new tools to study the organization of biomolecular machines

Spiropyrans as molecular optical switches.

scientific article

SuReSim: simulating localization microscopy experiments from ground truth models

scientific article

Subdiffraction fluorescence imaging of biomolecular structure and distributions with quantum dots

scientific article

Subdiffraction-resolution fluorescence imaging of proteins in the mitochondrial inner membrane with photoswitchable fluorophores

scientific article

Subdiffraction-resolution fluorescence imaging with conventional fluorescent probes

scientific article

Subdiffraction-resolution fluorescence microscopy of myosin-actin motility

scientific article

Super-chelators for advanced protein labeling in living cells.

scientific article published on 20 February 2018

Super-resolution fluorescence imaging of chromosomal DNA

scientific article published on 29 December 2011

Super-resolution imaging and estimation of protein copy numbers at single synapses with DNA-point accumulation for imaging in nanoscale topography

scientific article published on 01 July 2019

Super-resolution imaging of Escherichia coli nucleoids reveals highly structured and asymmetric segregation during fast growth.

scientific article

Super-resolution imaging reveals the internal architecture of nano-sized syntaxin clusters

scientific article

Super-resolution imaging visualizes the eightfold symmetry of gp210 proteins around the nuclear pore complex and resolves the central channel with nanometer resolution

scientific article published in February 2012

Super-resolution imaging with small organic fluorophores

scientific article published in January 2009

Super-resolution microscopy reveals specific recruitment of HIV-1 envelope proteins to viral assembly sites dependent on the envelope C-terminal tail.

scientific article

Super-resolved insights into human immunodeficiency virus biology.

scientific article published on 27 April 2016

Superresolution optical fluctuation imaging with organic dyes

scientific article

Surfing on a new wave of single-molecule fluorescence methods

scientific article

Switching at the ribosome: riboswitches need rProteins as modulators to regulate translation

scientific article published on 05 August 2021

TNF-α influences the lateral dynamics of TNF receptor I in living cells.

scientific article published on 27 June 2012

Targeting, resolving and quantifying cellular structures by single-molecule localization microscopy.

scientific article published on 13 November 2012

Temporal accumulation analysis provides simplified artifact-free analysis of membrane-protein nanoclusters.

scientific article

The Pearling Transition Provides Evidence of Force-Driven Endosomal Tubulation during Salmonella Infection.

scientific article

The effect of photoswitching kinetics and labeling densities on super-resolution fluorescence imaging

scientific article published on 20 February 2010

The metabolic capacity of lipid droplet localized acyl-CoA synthetase 3 is not sufficient to support local triglyceride synthesis independent of the endoplasmic reticulum in A431 cells

scientific article published on 09 March 2018

Three-dimensional, tomographic super-resolution fluorescence imaging of serially sectioned thick samples

scientific article

Transglutaminase 2 promotes tumorigenicity of colon cancer cells by inactivation of the tumor suppressor p53

scientific article published on 08 June 2021

Virtual-'light-sheet' single-molecule localisation microscopy enables quantitative optical sectioning for super-resolution imaging

scientific article

Visualizing ubiquitination in mammalian cells

scientific article published on 21 January 2019

Whole-Cell, 3D, and Multicolor STED Imaging with Exchangeable Fluorophores

dSTORM: real-time subdiffraction-resolution fluorescence imaging with organic fluorophores

scholarly article published 11 February 2010

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