List of works by Daniel J. Kelly

* Three-Dimensional Bioprinting of Polycaprolactone Reinforced Gene Activated Bioinks for Bone Tissue Engineering.

scientific article

3D Bioprinting for Cartilage and Osteochondral Tissue Engineering.

scientific article

3D Bioprinting of Developmentally Inspired Templates for Whole Bone Organ Engineering

scientific article published on 9 June 2016

3D bioprinting spatiotemporally defined patterns of growth factors to tightly control tissue regeneration

scientific article published on 14 August 2020

3D printed microchannel networks to direct vascularisation during endochondral bone repair.

scientific article published in February 2018

A Computational Model of Osteochondral Defect Repair Following Implantation of Stem Cell-Laden Multiphase Scaffolds

scientific article published on 6 October 2016

A collagen-based interface construct for the assessment of cell-dependent mechanical integration of tissue surfaces

scientific article published on 6 October 2006

A comparative study of shear stresses in collagen-glycosaminoglycan and calcium phosphate scaffolds in bone tissue-engineering bioreactors

scientific article published in May 2009

A comparison of different bioinks for 3D bioprinting of fibrocartilage and hyaline cartilage.

scientific article published on 7 October 2016

A comparison of fibrin, agarose and gellan gum hydrogels as carriers of stem cells and growth factor delivery microspheres for cartilage regeneration.

scientific article

A comparison of self-assembly and hydrogel encapsulation as a means to engineer functional cartilaginous grafts using culture expanded chondrocytes

scientific article published on 12 July 2013

A comparison of the functionality and in vivo phenotypic stability of cartilaginous tissues engineered from different stem cell sources

scientific article published on 27 April 2012

A computational model to explore the role of angiogenic impairment on endochondral ossification during fracture healing

scientific article published on 29 January 2016

A growth factor delivery system for chondrogenic induction of infrapatellar fat pad-derived stem cells in fibrin hydrogels

scientific article published on 23 September 2011

A mechano-regulation model of fracture repair in vertebral bodies

article

A mechanobiological model of endothelial cell migration and proliferation.

scientific article published on 16 December 2014

A model of tissue differentiation and bone remodelling in fractured vertebrae treated with minimally invasive percutaneous fixation

scientific article published on 30 June 2012

A remodelling metric for angular fibre distributions and its application to diseased carotid bifurcations

scientific article published on 16 November 2011

A role for the primary cilium in paracrine signaling between mechanically stimulated osteocytes and mesenchymal stem cells

scientific article published on 23 July 2011

A short history of bioengineering research in Ireland

scientific article published on 19 December 2017

Altering the architecture of tissue engineered hypertrophic cartilaginous grafts facilitates vascularisation and accelerates mineralisation

scientific article

Altering the swelling pressures within in vitro engineered cartilage is predicted to modulate the configuration of the collagen network and hence improve tissue mechanical properties.

scientific article published in April 2013

An Endochondral Ossification-Based Approach to Bone Repair: Chondrogenically Primed Mesenchymal Stem Cell-Laden Scaffolds Support Greater Repair of Critical-Sized Cranial Defects Than Osteogenically Stimulated Constructs In Vivo

scientific article published on 19 February 2016

An anisotropic inelastic constitutive model to describe stress softening and permanent deformation in arterial tissue

scientific article

An argument for the use of multiple segment stents in curved arteries

scientific article published in August 2011

An endochondral ossification approach to early-stage bone repair: Use of tissue-engineered hypertrophic cartilage constructs as primordial templates for weight-bearing bone repair.

scientific article

Anisotropic Shape-Memory Alginate Scaffolds Functionalized with Either Type I or Type II Collagen for Cartilage Tissue Engineering

scientific article published on 6 October 2016

Apparent behaviour of charged and neutral materials with ellipsoidal fibre distributions and cross-validation of finite element implementations

scientific article published on 21 January 2012

Biochemical markers of the mechanical quality of engineered hyaline cartilage

scientific article published in February 2007

Biofabrication of multiscale bone extracellular matrix scaffolds for bone tissue engineering

scientific article published on 11 October 2019

Biofabrication of soft tissue templates for engineering the bone-ligament interface.

scientific article published on 19 June 2017

Biofabrication of spatially organised tissues by directing the growth of cellular spheroids within 3D printed polymeric microchambers

scientific article published on 08 January 2019

Can the theory of critical distances predict the failure of shape memory alloys?

scientific article published in June 2011

Cell-matrix interactions regulate mesenchymal stem cell response to hydrostatic pressure

scientific article published on 13 March 2012

Chondrocyte-based intraoperative processing strategies for the biological augmentation of a polyurethane meniscus replacement.

scientific article published on 28 November 2017

Chondrocytes and bone marrow-derived mesenchymal stem cells undergoing chondrogenesis in agarose hydrogels of solid and channelled architectures respond differentially to dynamic culture conditions

scientific article published on 10 January 2011

Chondrogenesis and integration of mesenchymal stem cells within an in vitro cartilage defect repair model

scientific article published on 12 September 2009

Chondrogenesis of embryonic limb bud cells in micromass culture progresses rapidly to hypertrophy and is modulated by hydrostatic pressure.

scientific article published on 22 October 2016

Combining freshly isolated chondroprogenitor cells from the infrapatellar fat pad with a growth factor delivery hydrogel as a putative single stage therapy for articular cartilage repair

scientific article published on 12 November 2013

Comparison of the vulnerability risk for positive versus negative atheroma plaque morphology

scientific article

Composition-function relations of cartilaginous tissues engineered from chondrocytes and mesenchymal stem cells isolated from bone marrow and infrapatellar fat pad

scientific article published on 29 December 2010

Computational simulation methodologies for mechanobiological modelling: a cell-centred approach to neointima development in stents

scientific article

Controlled release of transforming growth factor-β3 from cartilage-extra-cellular-matrix-derived scaffolds to promote chondrogenesis of human-joint-tissue-derived stem cells.

scientific article published on 4 June 2014

Coupling Freshly Isolated CD44(+) Infrapatellar Fat Pad-Derived Stromal Cells with a TGF-β3 Eluting Cartilage ECM-Derived Scaffold as a Single-Stage Strategy for Promoting Chondrogenesis

scientific article published on 6 February 2015

Cyclic Tensile Strain Can Play a Role in Directing both Intramembranous and Endochondral Ossification of Mesenchymal Stem Cells

scientific article published on 27 November 2017

Cyclic hydrostatic pressure promotes a stable cartilage phenotype and enhances the functional development of cartilaginous grafts engineered using multipotent stromal cells isolated from bone marrow and infrapatellar fat pad.

scientific article published on 13 December 2013

Decellularization of porcine articular cartilage explants and their subsequent repopulation with human chondroprogenitor cells.

scientific article published on 22 October 2015

Deformation simulation of cells seeded on a collagen-GAG scaffold in a flow perfusion bioreactor using a sequential 3D CFD-elastostatics model

article

Development of a Platform for Studying 3D Astrocyte Mechanobiology: Compression of Astrocytes in Collagen Gels

scientific article published on 27 November 2017

Direct UV-Triggered Thiol-ene Cross-Linking of Electrospun Polyester Fibers from Unsaturated Poly(macrolactone)s and Their Drug Loading by Solvent Swelling

scientific article published on 14 November 2017

Dual non-viral gene delivery from microparticles within 3D high-density stem cell constructs for enhanced bone tissue engineering.

scientific article published on 3 January 2018

Dynamic compression can inhibit chondrogenesis of mesenchymal stem cells

scientific article published on 11 October 2008

Editorial. The mechanical behaviour of cells, tissues and biomaterials

scientific article published on 01 October 2014

Effect of a degraded core on the mechanical behaviour of tissue-engineered cartilage constructs: a poro-elastic finite element analysis.

scientific article published in January 2004

Effects of in vitro preculture on in vivo development of human engineered cartilage in an ectopic model

scientific article published in September 2005

Electrospinning of highly porous yet mechanically functional microfibrillar scaffolds at the human scale for ligament and tendon tissue engineering

scientific article published on 15 April 2019

Engineering articular cartilage-like grafts by self-assembly of infrapatellar fat pad-derived stem cells.

scientific article published in August 2014

Engineering cartilage or endochondral bone: a comparison of different naturally derived hydrogels.

scientific article

Engineering cartilaginous grafts using chondrocyte-laden hydrogels supported by a superficial layer of stem cells

scientific article published on 26 May 2015

Engineering large cartilage tissues using dynamic bioreactor culture at defined oxygen conditions.

scientific article published on 24 January 2018

Engineering of large cartilaginous tissues through the use of microchanneled hydrogels and rotational culture

scientific article published on 01 November 2009

Engineering osteochondral constructs through spatial regulation of endochondral ossification

scientific article published on 14 November 2012

Engineering zonal cartilaginous tissue by modulating oxygen levels and mechanical cues through the depth of infrapatellar fat pad stem cell laden hydrogels.

scientific article published on 3 May 2016

European Society of Biomechanics S.M. Perren Award 2012: the external mechanical environment can override the influence of local substrate in determining stem cell fate.

scientific article published on 25 August 2012

Evaluation of bone marrow stem cell response to PLA scaffolds manufactured by 3D printing and coated with polydopamine and type I collagen.

scientific article published on 26 February 2018

Expansion in the presence of FGF-2 enhances the functional development of cartilaginous tissues engineered using infrapatellar fat pad derived MSCs

scientific article published on 17 September 2011

Exploring the roles of integrin binding and cytoskeletal reorganization during mesenchymal stem cell mechanotransduction in soft and stiff hydrogels subjected to dynamic compression.

scientific article published on 14 August 2013

Fiber Reinforced Cartilage ECM Functionalized Bioinks for Functional Cartilage Tissue Engineering

scientific article published on 09 January 2019

Fibrin hydrogels functionalized with cartilage extracellular matrix and incorporating freshly isolated stromal cells as an injectable for cartilage regeneration

scientific article published on 4 March 2016

Finite element modelling of diseased carotid bifurcations generated from in vivo computerised tomographic angiography

scientific article published on 7 March 2010

Functional properties of cartilaginous tissues engineered from infrapatellar fat pad-derived mesenchymal stem cells

scientific article published on 14 December 2009

Gene Delivery of TGF-β3 and BMP2 in an MSC-Laden Alginate Hydrogel for Articular Cartilage and Endochondral Bone Tissue Engineering

scientific article

Glyoxal cross-linking of solubilized extracellular matrix to produce highly porous, elastic, and chondro-permissive scaffolds for orthopedic tissue engineering

scientific article published on 11 June 2019

Growth plate extracellular matrix-derived scaffolds for large bone defect healing.

scientific article published on 14 February 2017

Hierarchically Structured Electrospun Scaffolds with Chemically Conjugated Growth Factor for Ligament Tissue Engineering

scientific article published on 27 March 2017

Hypoxia mimicking hydrogels to regulate the fate of transplanted stem cells

scientific article published on 27 February 2019

Identification of mechanosensitive genes during skeletal development: alteration of genes associated with cytoskeletal rearrangement and cell signalling pathways

scientific journal article

Inelasticity of human carotid atherosclerotic plaque

scientific article

Influence of oxygen levels on chondrogenesis of porcine mesenchymal stem cells cultured in polycaprolactone scaffolds.

scientific article published on 20 February 2017

Infrapatellar Fat Pad Stem Cells: From Developmental Biology to Cell Therapy

scientific article published on 6 September 2017

Infrapatellar fat pad-derived stem cells maintain their chondrogenic capacity in disease and can be used to engineer cartilaginous grafts of clinically relevant dimensions

scientific article published on 8 July 2014

Integrating finite element modelling and 3D printing to engineer biomimetic polymeric scaffolds for tissue engineering

scientific article published on 08 September 2019

Low oxygen tension is a more potent promoter of chondrogenic differentiation than dynamic compression

scientific article published on 16 June 2010

Low-oxygen conditions promote synergistic increases in chondrogenesis during co-culture of human osteoarthritic stem cells and chondrocytes.

scientific article published on 26 November 2017

Macrophage Polarization in Response to Collagen Scaffold Stiffness Is Dependent on Cross-Linking Agent Used To Modulate the Stiffness

scientific article published on 17 December 2018

Material stiffness influences the polarization state, function and migration mode of macrophages

scientific article published on 28 February 2019

Measuring and Modeling Oxygen Transport and Consumption in 3D Hydrogels Containing Chondrocytes and Stem Cells of Different Tissue Origins

scientific article published on 25 May 2021

Mechanical Characterization of Fresh Human Carotid Atherosclerotic Plaque

Mechanical Testing of Cartilage Constructs.

scientific article published in January 2015

Mechanical properties and cellular response of novel electrospun nanofibers for ligament tissue engineering: Effects of orientation and geometry

scientific article published on 31 March 2016

Mechanical properties of a hierarchical electrospun scaffold for ovine anterior cruciate ligament replacement

scientific article published on 03 January 2019

Mechanical regulation of mesenchymal stem cell differentiation.

scientific article

Mechanically induced structural changes during dynamic compression of engineered cartilaginous constructs can potentially explain increases in bulk mechanical properties

scientific article published on 7 September 2011

Mechano-regulation of mesenchymal stem cell differentiation and collagen organisation during skeletal tissue repair

scientific article published on 29 December 2009

Mechano-regulation of stem cell differentiation and tissue regeneration in osteochondral defects

scientific article

Meniscus ECM-functionalised hydrogels containing infrapatellar fat pad-derived stem cells for bioprinting of regionally defined meniscal tissue

scientific article published on 3 November 2017

Mesenchymal stem cell fate following non-viral gene transfection strongly depends on the choice of delivery vector

scientific article published on 28 March 2017

Modulating gradients in regulatory signals within mesenchymal stem cell seeded hydrogels: a novel strategy to engineer zonal articular cartilage.

scientific article

Modulating microfibrillar alignment and growth factor stimulation to regulate mesenchymal stem cell differentiation

scientific article published on 7 October 2017

Obtaining the sGAG distribution profile in articular cartilage color images

scientific article published on 01 September 2019

Optimizing stem cell engineering for orthopaedic applications.

scientific article

Orthopaedic implant materials drive M1 macrophage polarization in a spleen tyrosine kinase- and mitogen-activated protein kinase-dependent manner.

scientific article published on 2 November 2017

Osteoarthritis-associated basic calcium phosphate crystals alter immune cell metabolism and promote M1 macrophage polarization

scientific article published on 12 November 2019

Oxygen tension differentially regulates the functional properties of cartilaginous tissues engineered from infrapatellar fat pad derived MSCs and articular chondrocytes.

scientific article

Oxygen tension regulates the osteogenic, chondrogenic and endochondral phenotype of bone marrow derived mesenchymal stem cells

scientific article published in December 2011

Patient Specific Finite Element Modelling of the Carotid Bifurcation

Pore-forming bioinks to enable spatio-temporally defined gene delivery in bioprinted tissues

scientific article published on 08 March 2019

Porous decellularized tissue engineered hypertrophic cartilage as a scaffold for large bone defect healing.

scientific article published on 31 May 2015

Prediction of fibre architecture and adaptation in diseased carotid bifurcations.

scientific article published on 16 December 2010

Prediction of the optimal mechanical properties for a scaffold used in osteochondral defect repair

scientific article published in September 2006

Purinergic Signaling Regulates the Transforming Growth Factor-β3-Induced Chondrogenic Response of Mesenchymal Stem Cells to Hydrostatic Pressure

scientific article published on 2 May 2016

Recapitulating aspects of the oxygen and substrate environment of the damaged joint milieu for stem cell-based cartilage tissue engineering

scientific article published on 17 September 2012

Recapitulating bone development through engineered mesenchymal condensations and mechanical cues for tissue regeneration

scientific article published on 01 June 2019

Recapitulating endochondral ossification: a promising route to in vivo bone regeneration

scientific article

Regeneration of osteochondral defects using developmentally inspired cartilaginous templates

scientific article published on 31 December 2018

Reinforcing interpenetrating network hydrogels with 3D printed polymer networks to engineer cartilage mimetic composites

scientific article published on 06 April 2020

Remodelling of collagen fibre transition stretch and angular distribution in soft biological tissues and cell-seeded hydrogels

scientific article published on 25 May 2011

Role of oxygen as a regulator of stem cell fate during the spontaneous repair of osteochondral defects

scientific article published on 23 November 2015

Scaffold architecture determines chondrocyte response to externally applied dynamic compression.

scientific article

Simple Radical Polymerization of Poly(Alginate-Graft-N-Isopropylacrylamide) Injectable Thermoresponsive Hydrogel with the Potential for Localized and Sustained Delivery of Stem Cells and Bioactive Molecules

scientific article published on 17 July 2017

Simulation of a balloon expandable stent in a realistic coronary artery—Determination of the optimum modelling strategy

article

Simulation of tissue differentiation in a scaffold as a function of porosity, Young's modulus and dissolution rate: application of mechanobiological models in tissue engineering

scientific article published on 25 September 2007

Site specific inelasticity of arterial tissue

scientific article published on 22 March 2012

Spatial patterning of phenotypically distinct microtissues to engineer osteochondral grafts for biological joint resurfacing

scientific article published in 2022

Stem cells display a donor dependent response to escalating levels of growth factor release from extracellular matrix-derived scaffolds

scientific article published on 12 July 2016

Stimulation of osteoblasts using rest periods during bioreactor culture on collagen-glycosaminoglycan scaffolds.

scientific article

Stresses in peripheral arteries following stent placement: a finite element analysis

scientific article published in February 2009

Substrate stiffness and oxygen as regulators of stem cell differentiation during skeletal tissue regeneration: a mechanobiological model.

scientific article

Substrate stiffness and oxygen availability as regulators of mesenchymal stem cell differentiation within a mechanically loaded bone chamber.

scientific article published on 16 May 2014

Temporal and spatial changes in cartilage-matrix-specific gene expression in mesenchymal stem cells in response to dynamic compression.

scientific article

Tensile and compressive properties of fresh human carotid atherosclerotic plaques

scientific article published on 18 September 2009

The Influence of Fiber Orientation on the Equilibrium Properties of Neutral and Charged Biphasic Tissues ⬇️

scientific article published on 01 November 2010

The Response of Bone Marrow-Derived Mesenchymal Stem Cells to Dynamic Compression Following TGF-β3 Induced Chondrogenic Differentiation

article

The application of plastic compression to modulate fibrin hydrogel mechanical properties

scientific article published on 27 October 2012

The changing role of the superficial region in determining the dynamic compressive properties of articular cartilage during postnatal development

scientific article published on 11 February 2015

The composition of engineered cartilage at the time of implantation determines the likelihood of regenerating tissue with a normal collagen architecture

scientific article published on 6 December 2012

The consequences of the mechanical environment of peripheral arteries for nitinol stenting

scientific article published on 11 August 2011

The effect of concentration, thermal history and cell seeding density on the initial mechanical properties of agarose hydrogels

scientific article published on 30 December 2008

The effect of cyclic hydrostatic pressure on the functional development of cartilaginous tissues engineered using bone marrow derived mesenchymal stem cells

scientific article published on 22 April 2011

The effect of prosthesis design on vibration of the reconstructed ossicular chain: a comparative finite element analysis of four prostheses

scientific article published in January 2003

The effect of ventilation tubes on stresses and vibration motion in the tympanic membrane: a finite element analysis

scientific article published on 01 December 1999

The effects of dynamic compression on the development of cartilage grafts engineered using bone marrow and infrapatellar fat pad derived stem cells.

scientific article published on 21 September 2015

The influence of construct scale on the composition and functional properties of cartilaginous tissues engineered using bone marrow-derived mesenchymal stem cells

scientific article published on 02 November 2011

The influence of expansion rates on mandibular distraction osteogenesis: a computational analysis.

scientific article published on 4 September 2007

The influence of plaque composition on underlying arterial wall stress during stent expansion: The case for lesion-specific stents

article

The influence of ventilation tube design on the magnitude of stress imposed at the implant/tympanic membrane interface

scientific article published on 24 May 2007

The role of environmental factors in regulating the development of cartilaginous grafts engineered using osteoarthritic human infrapatellar fat pad-derived stem cells

scientific article

The role of oxygen as a regulator of stem cell fate during fracture repair in TSP2-null mice

scientific article published on 15 June 2013

The role of the superficial region in determining the dynamic properties of articular cartilage.

scientific article published on 10 August 2012

The role of vessel geometry and material properties on the mechanics of stenting in the coronary and peripheral arteries

scientific article published on 01 January 2010

The shape and size of hydroxyapatite particles dictate inflammatory responses following implantation

scientific article

Tissue differentiation and bone regeneration in an osteotomized mandible: a computational analysis of the latency period

scientific article published on 27 September 2007

Tissue-specific extracellular matrix scaffolds for the regeneration of spatially complex musculoskeletal tissues

scientific article published on 04 October 2018

Tuning Alginate Bioink Stiffness and Composition for Controlled Growth Factor Delivery and to Spatially Direct MSC Fate within Bioprinted Tissues

scientific article published on 6 December 2017

Unravelling the Role of Mechanical Stimuli in Regulating Cell Fate During Osteochondral Defect Repair

scientific article

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