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List of works by Matthias Merkenschlager

A conserved insulator that recruits CTCF and cohesin exists between the closely related but divergently regulated interleukin-3 and granulocyte-macrophage colony-stimulating factor genes.

scientific article

A high-resolution map of transcriptional repression

scientific article published on 20 March 2017

A role for Dicer in immune regulation

scientific article

A role for cohesin in T-cell-receptor rearrangement and thymocyte differentiation

scientific article

A unilateral negative feedback loop between miR-200 microRNAs and Sox2/E2F3 controls neural progenitor cell-cycle exit and differentiation

scientific article published on September 2012

Acquisition and extinction of gene expression programs are separable events in heterokaryon reprogramming

scientific article published on 25 April 2006

Allorecognition of HLA-DR and -DQ transfectants by human CD45RA and CD45R0 CD4 T cells: repertoire analysis and activation requirements

scientific article published on January 1991

An early developmental role for miRNAs in the maintenance of extraembryonic stem cells in the mouse embryo

scientific journal article

Analysis of Cohesin Function in Gene Regulation and Chromatin Organization in Interphase

scientific article published in January 2017

B cell growth and differentiation induced by supernatants of transformed epithelial cell lines

scientific article published in August 1986

Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia.

scientific article

Building gene regulatory networks from scATAC-seq and scRNA-seq using Linked Self Organizing Maps

scientific article published on 04 November 2019

Building gene regulatory networks from single-cell ATAC-seq and RNA-seq using Linked Self-Organizing Maps

article

CD45 isoform switching precedes the activation-driven death of human thymocytes by apoptosis

scientific article published on 01 January 1991

CTCF and Cohesin in Genome Folding and Transcriptional Gene Regulation

scientific article published on 18 April 2016

CTCF and cohesin: linking gene regulatory elements with their targets

scientific article published on March 2013

Cdc14 phosphatase promotes segregation of telomeres through repression of RNA polymerase II transcription.

scientific article published on 23 October 2011

Centromeric repositioning of coreceptor loci predicts their stable silencing and the CD4/CD8 lineage choice.

scientific article

Chromatin signatures of pluripotent cell lines

scientific article (publication date: May 2006)

Chromatinization of with archaeal histones

scientific article published on 06 November 2019

Chromosomes and expression mechanisms: life on the edge

scientific article published on 6 April 2009

Cohesin and chromatin organisation

scientific article published on 10 December 2011

Cohesin at active genes: a unifying theme for cohesin and gene expression from model organisms to humans

scientific article

Cohesin's role in pluripotency and reprogramming

scientific article published on 23 December 2015

Cohesin, CTCF and lymphocyte antigen receptor locus rearrangement

scientific article published on 20 March 2012

Cohesin-based chromatin interactions enable regulated gene expression within preexisting architectural compartments

scientific article published on 03 September 2013

Cohesin-dependence of neuronal gene expression relates to chromatin loop length

scientific article published on 26 April 2022

Cohesin: a global player in chromosome biology with local ties to gene regulation.

scientific article published on 11 June 2010

Cohesins form chromosomal cis-interactions at the developmentally regulated IFNG locus

scientific article

Cohesins functionally associate with CTCF on mammalian chromosome arms

scientific article (publication date: 8 February 2008)

Comparison of the frequency of peptide-specific cytotoxic T lymphocytes restricted by self- and allo-MHC following in vitro T cell priming

scientific article published on November 2002

Condensin goes with the family but not with the flow

scientific article published on 06 October 2008

Condensin, cohesin and the control of chromatin states.

scientific article published on 09 January 2013

Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation

article

Correction of severe anaemia using immuno-regulated gene therapy is achieved by restoring the early erythroblast compartment

scientific article published in March 2006

DNA synthesis is required for reprogramming mediated by stem cell fusion

scientific article published on February 2013

Data integration in the era of omics: current and future challenges

scientific article

Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage

scientific article published on March 2008

Dicer is required for Sertoli cell function and survival.

scientific article

Dicer regulates Xist promoter methylation in ES cells indirectly through transcriptional control of Dnmt3a

scientific article

Dicer-dependent microRNA pathway controls invariant NKT cell development.

scientific article

Dicer-dependent pathways regulate chondrocyte proliferation and differentiation

scholarly article

Differences in the epigenetic and reprogramming properties of pluripotent and extra-embryonic stem cells implicate chromatin remodelling as an important early event in the developing mouse embryo

scientific article

Different Roles for Tet1 and Tet2 Proteins in Reprogramming-Mediated Erasure of Imprints Induced by EGC Fusion.

scientific article published in March 2013

Different doses of agonistic ligand drive the maturation of functional CD4 and CD8 T cells from immature precursors

scientific article published on 01 February 2000

Different roles for Tet1 and Tet2 proteins in reprogramming-mediated erasure of imprints induced by EGC fusion

scientific article published on 28 February 2013

Direct interaction of Ikaros and Foxp1 modulates expression of the G protein-coupled receptor G2A in B-lymphocytes and acute lymphoblastic leukemia.

scientific article published on 30 August 2016

Down-regulation of TDT transcription in CD4(+)CD8(+) thymocytes by Ikaros proteins in direct competition with an Ets activator

scientific article

Dynamic assembly of silent chromatin during thymocyte maturation

scientific article published on 18 April 2004

Dynamic repositioning of genes in the nucleus of lymphocytes preparing for cell division

scientific article published on February 1999

ESCs require PRC2 to direct the successful reprogramming of differentiated cells toward pluripotency

scientific article published on June 2010

Embryonic stem cell-derived hemangioblasts remain epigenetically plastic and require PRC1 to prevent neural gene expression.

scientific article published on 28 September 2010

Epigenetic changes induced by in utero dietary challenge result in phenotypic variability in successive generations of mice

scientific article published on 05 May 2022

Evolutionary conservation, developmental expression, and genomic mapping of mammalian

Expression of alpha- and beta-globin genes occurs within different nuclear domains in haemopoietic cells.

scientific article published in June 2001

Extensive microRNA-mediated crosstalk between lncRNAs and mRNAs in mouse embryonic stem cells

scientific article published on 19 March 2015

Feedforward regulation of Myc coordinates lineage-specific with housekeeping gene expression during B cell progenitor cell differentiation

article

Focus on epigenetic control of host defence: editorial

scientific article published in July 2013

Fresh powder on Waddington's slopes

scientific article published on 18 June 2010

Genome-wide identification of Ikaros targets elucidates its contribution to mouse B-cell lineage specification and pre-B-cell differentiation

scientific article

Heritable gene silencing in lymphocytes delays chromatid resolution without affecting the timing of DNA replication

article

Heterokaryon-based reprogramming of human B lymphocytes for pluripotency requires Oct4 but not Sox2.

scientific article

Histone hypomethylation is an indicator of epigenetic plasticity in quiescent lymphocytes

scientific article published on 28 October 2004

How Many Thymocytes Audition for Selection?

scientific article published on October 6, 1997

IL4 blockade of inducible regulatory T cell differentiation: the role of Th2 cells, Gata3 and PU.1.

scientific article published on 29 November 2008

Identifying proteins bound to native mitotic ESC chromosomes reveals chromatin repressors are important for compaction

scientific article published on 17 August 2020

Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits.

scientific article published in March 2007

Ikaros in immune receptor signaling, lymphocyte differentiation, and function.

scientific article published on 02 October 2010

Initiation and maintenance of pluripotency gene expression in the absence of cohesin

scientific article

Is REST required for ESC pluripotency?

scientific article published in February 2009

Jarid2 Coordinates Nanog Expression and PCP/Wnt Signaling Required for Efficient ESC Differentiation and Early Embryo Development

scientific article published on 16 July 2015

Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators.

scientific article published on 16 May 2010

Jarid2 links MicroRNA and chromatin in Th17 cells

scientific article published on 01 June 2014

Limiting dilution analysis of proliferative responses in human lymphocyte populations defined by the monoclonal antibody UCHL1: implications for differential CD45 expression in T cell memory formation.

scientific article published in November 1988

Long-range regulation of cytokine gene expression.

scientific article published on 15 May 2008

Lymphoproliferative disorders in IL-7 transgenic mice: expansion of immature B cells which retain macrophage potential.

scientific article published in March 1995

Memory T cells.

scientific article published in October 1989

MicroRNA loss enhances learning and memory in mice

scientific article

MicroRNA targeting of CoREST controls polarization of migrating cortical neurons

scientific article published in May 2014

MicroRNAs of the miR-290-295 Family Maintain Bivalency in Mouse Embryonic Stem Cells.

scientific article published on 13 April 2016

Neural induction promotes large-scale chromatin reorganisation of the Mash1 locus.

scientific article published on January 2006

Neuronal genes deregulated in Cornelia de Lange Syndrome respond to removal and re-expression of cohesin

scientific article published on 18 May 2021

Nonequivalent nuclear location of immunoglobulin alleles in B lymphocytes.

scientific article

Nuclear repositioning marks the selective exclusion of lineage-inappropriate transcription factor loci during T helper cell differentiation

scientific article published in December 2004

Oncometabolite Tinkers with Genome Folding, Boosting Oncogene Expression.

scientific article published on 5 February 2016

Ordered chromatin changes and human X chromosome reactivation by cell fusion-mediated pluripotent reprogramming

scientific article published on 10 August 2016

PI3 kinase signalling blocks Foxp3 expression by sequestering Foxo factors

scientific article

Podocyte-selective deletion of dicer induces proteinuria and glomerulosclerosis

scientific article

Progress in T cell biology

scientific article published in December 1987

REST selectively represses a subset of RE1-containing neuronal genes in mouse embryonic stem cells

scientific article published in March 2009

RNAi and chromatin in T cell development and function

scientific article published on 25 April 2008

Rational primer design greatly improves differential display-PCR (DD-PCR).

scientific article published on June 1997

Recessive expression of the H2A-controlled immune response phenotype depends critically on antigen dose

scientific article published on 01 February 2000

Runx proteins regulate Foxp3 expression

scientific article published on 19 October 2009

Selective deployment of transcription factor paralogs with submaximal strength facilitates gene regulation in the immune system

scientific article published on 26 August 2019

Sensory adaptation in naive peripheral CD4 T cells

scientific article

Small RNAs control sodium channel expression, nociceptor excitability, and pain thresholds

scientific article

Spatial enhancer clustering and regulation of enhancer-proximal genes by cohesin

scientific article published on 12 February 2015

T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR.

scholarly article

The developmentally regulated expression of Twisted gastrulation reveals a role for bone morphogenetic proteins in the control of T cell development

scientific article

The impact of chromatin modifiers on the timing of locus replication in mouse embryonic stem cells

scientific article published on January 2007

The regulated long-term delivery of therapeutic proteins by using antigen-specific B lymphocytes.

scholarly article

The reorganisation of constitutive heterochromatin in differentiating muscle requires HDAC activity

scientific article published on 21 September 2005

The tight interallelic positional coincidence that distinguishes T-cell receptor Jalpha usage does not result from homologous chromosomal pairing during ValphaJalpha rearrangement

scientific article

Tracing interactions of thymocytes with individual stromal cell partners

scientific article published on 01 April 1996

Upstream of Ikaros.

scientific article published on November 2003

Using heterokaryons to understand pluripotency and reprogramming

scientific article

microRNA-mediated regulation of mTOR complex components facilitates discrimination between activation and anergy in CD4 T cells.

scientific article

microRNAs calibrate T cell responses by regulating mTOR.

scientific article published on 13 October 2015

microRNAs regulate cell-to-cell variability of endogenous target gene expression in developing mouse thymocytes.

scientific article published on 25 February 2015