Search filters

List of works by Karin Thevissen

2-(2-oxo-morpholin-3-yl)-acetamide derivatives as broad-spectrum antifungal agents.

scientific article

A Linear 19-Mer Plant Defensin-Derived Peptide Acts Synergistically with Caspofungin against Candida albicans Biofilms

scientific article published on 20 October 2017

A fungicidal piperazine-1-carboxamidine induces mitochondrial fission-dependent apoptosis in yeast

scientific article published on 18 August 2010

Affinity comparison of p3 and p8 peptide displaying bacteriophages using surface plasmon resonance

scientific article

Alternating Current Electrophoretic Deposition for the Immobilization of Antimicrobial Agents on Titanium Implant Surfaces.

scientific article published on 17 February 2017

An antibiofilm coating of 5-aryl-2-aminoimidazole covalently attached to a titanium surface

scientific article published on 13 December 2018

Angiotensin II type 1 receptor blockers increase tolerance of cells to copper and cisplatin.

scientific article

Antibacterial activity of a new broad-spectrum antibiotic covalently bound to titanium surfaces.

scientific article

Antibacterial and antifungal properties of alpha-helical, cationic peptides in the venom of scorpions from southern Africa.

scientific article published in October 2002

Antibiotic activities of host defense peptides: more to it than lipid bilayer perturbation.

scientific article published on 27 May 2011

Antifungal activity in plants from Chinese traditional and folk medicine

scientific article published on 31 July 2012

Antifungal activity of synthetic peptides derived from Impatiens balsamina antimicrobial peptides Ib-AMP1 and Ib-AMP4.

scientific article published on 16 February 2005

Antifungal carbazoles.

scientific article published on January 2009

Antifungal plant defensins: increased insight in their mode of action as a basis for their use to combat fungal infections

scientific article published on 24 March 2017

Antifungal plant defensins: mechanisms of action and production

scientific article

Antimicrobial Peptides as a Strategy to Combat Fungal Biofilms

scientific article

Apoptosis-inducing antifungal peptides and proteins.

scientific article published on October 2011

Arabidopsis thaliana plants expressing human beta-defensin-2 are more resistant to fungal attack: functional homology between plant and human defensins

article

Artemisinins, new miconazole potentiators resulting in increased activity against Candida albicans biofilms.

scientific article

Azoles: Mode of Antifungal Action and Resistance Development. Effect of Miconazole on Endogenous Reactive Oxygen Species Production in Candida albicans

Ceramide involvement in apoptosis and apoptotic diseases.

scientific article published on June 2006

Combination Therapy to Treat Fungal Biofilm-Based Infections

scientific article published on 23 November 2020

Combination of miconazole and domiphen bromide is fungicidal against biofilms of resistant Candida spp

scientific article published on 20 July 2020

Combinatorial drug approaches to tackle Candida albicans biofilms

scientific article published on 12 June 2015

Combining Biocontrol Agents with Chemical Fungicides for Integrated Plant Fungal Disease Control

scientific article published on 04 December 2020

Controlled release of chlorhexidine antiseptic from microporous amorphous silica applied in open porosity of an implant surface

scientific article published on 20 July 2011

Controlled release of chlorhexidine from a mesoporous silica-containing macroporous titanium dental implant prevents microbial biofilm formation.

scientific article published on 11 January 2017

Correction to: International survey on influenza-associated pulmonary aspergillosis (IAPA) in intensive care units: responses suggest low awareness and potential underdiagnosis outside Europe

scientific article published on 29 April 2020

Covalent immobilization of antimicrobial agents on titanium prevents Staphylococcus aureus and Candida albicans colonization and biofilm formation.

scientific article published on 24 December 2015

Currently used antimycotics: spectrum, mode of action and resistance occurrence.

scientific article

Defensins from insects and plants interact with fungal glucosylceramides

scientific article published on 6 November 2003

Derivatives of the mouse cathelicidin-related antimicrobial peptide (CRAMP) inhibit fungal and bacterial biofilm formation

scientific article published on 30 June 2014

Design and synthesis of a series of piperazine-1-carboxamidine derivatives with antifungal activity resulting from accumulation of endogenous reactive oxygen species.

scientific article

Dietary intervention, but not losartan, completely reverses non-alcoholic steatohepatitis in obese and insulin resistant mice.

scientific article published on 23 February 2017

Digital microfluidics for time-resolved cytotoxicity studies on single non-adherent yeast cells

scientific article published on April 2015

DmAMP1, an antifungal plant defensin from dahlia (Dahlia merckii), interacts with sphingolipids from Saccharomyces cerevisiae

scientific article published in September 2003

Editorial [Hot Topic: Fungal Infections and Antifungal Strategies (Guest Editor: Karin Thevissen)]

scientific article published on 01 December 2005

Elucidation of the Mode of Action of a New Antibacterial Compound Active against Staphylococcus aureus and Pseudomonas aeruginosa ⬇️

scientific article

Establishing a Unified COVID-19 "Immunome": Integrating Coronavirus Pathogenesis and Host Immunopathology

scientific article published on 03 July 2020

Evaluation of the toxicity of 5-aryl-2-aminoimidazole-based biofilm inhibitors against eukaryotic cell lines, bone cells and the nematode Caenorhabditis elegans.

scientific article

Expanding the pharmacological profile of κ-hefutoxin 1 and analogues: A focus on the inhibitory effect on the oncogenic channel Kv10.1.

scientific article published on 28 August 2016

From Regulated Cell Death to Adaptive Stress Strategies: Convergence and Divergence in Eukaryotic Cells

Fungal Glucosylceramide-Specific Camelid Single Domain Antibodies Are Characterized by Broad Spectrum Antifungal Activity.

scientific article

Fungal Membrane Responses Induced by Plant Defensins and Thionins

scientific article published in Journal of Biological Chemistry

Fungal sphingolipids as targets for the development of selective antifungal therapeutics.

scientific article

Fungal β-1,3-glucan increases ofloxacin tolerance of Escherichia coli in a polymicrobial E. coli/Candida albicans biofilm.

scientific article published on 9 March 2015

Fungicidal activity of truncated analogues of dihydrosphingosine

scientific article published on 20 May 2008

Genome-wide expression analysis reveals TORC1-dependent and -independent functions of Sch9.

scientific article published on 28 August 2008

Guidelines and recommendations on yeast cell death nomenclature.

scientific article published in January 2018

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

How promising are combinatorial drug strategies in combating Candida albicans biofilms?

scientific article published on 27 July 2016

IPT1-independent sphingolipid biosynthesis and yeast inhibition by syringomycin E and plant defensin DmAMP1.

scientific article

Identification and characterization of an anti-pseudomonal dichlorocarbazol derivative displaying anti-biofilm activity

scholarly article by Veerle Liebens et al published 1 December 2014 in Bioorganic & Medicinal Chemistry Letters

Identification of fungicidal 2,6-disubstituted quinolines with activity against Candida biofilms

scientific article published on 18 October 2012

Identification of survival-promoting OSIP108 peptide variants and their internalization in human cells

scientific article published in August 2016

Implant functionalization with mesoporous silica: A promising antibac terial strategy, but does such an implant osseointegrate?

scientific article published on 31 December 2020

In vitro activity of the antiasthmatic drug zafirlukast against the oral pathogens Porphyromonas gingivalis and Streptococcus mutans

scientific article published on 12 January 2017

In vitro activity of the antifungal plant defensin RsAFP2 against Candida isolates and its in vivo efficacy in prophylactic murine models of candidiasis

scientific article published on 29 September 2008

In vitro methods for the evaluation of antimicrobial surface designs

scientific article published on 9 February 2018

Increasing the Fungicidal Action of Amphotericin B by Inhibiting the Nitric Oxide-Dependent Tolerance Pathway.

scientific article

Interactions of antifungal plant defensins with fungal membrane components.

scientific article published on November 2003

International survey on influenza-associated pulmonary aspergillosis (IAPA) in intensive care units: responses suggest low awareness and potential underdiagnosis outside Europe

scientific article published on 11 March 2020

Isolation and characterisation of plant defensins from seeds of Asteraceae, Fabaceae, Hippocastanaceae and Saxifragaceae

article

Isolation and characterization of Neurospora crassa mutants resistant to antifungal plant defensins

scientific article published in November 2003

Joined in death: highlights of the Sixth International Meeting on Yeast Apoptosis in Leuven, Belgium, 30 April-4 May 2008.

scientific article

Level of M(IP)2C sphingolipid affects plant defensin sensitivity, oxidative stress resistance and chronological life-span in yeast

scientific article published on 3 March 2006

Membrane rafts are involved in intracellular miconazole accumulation in yeast cells.

scientific article published on 25 September 2009

Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms.

scientific article published on 14 June 2018

Miconazole Induces Changes in Actin Cytoskeleton prior to Reactive Oxygen Species Induction in Yeast

scientific article published in Journal of Biological Chemistry

Mining the genome of Arabidopsis thaliana as a basis for the identification of novel bioactive peptides involved in oxidative stress tolerance

scientific article

Mitochondrial dysfunction leads to reduced chronological lifespan and increased apoptosis in yeast

scientific article

Mode of action of plant defensins suggests therapeutic potential

scientific article

Modes of antifungal action and in planta functions of plant defensins and defensin-like peptides

article

Modulation of the Substitution Pattern of 5-Aryl-2-Aminoimidazoles Allows Fine-Tuning of Their Antibiofilm Activity Spectrum and Toxicity.

scientific article published on 22 August 2016

Mutational Analysis of a Plant Defensin from Radish (Raphanus sativusL.) Reveals Two Adjacent Sites Important for Antifungal Activity

scientific article published in Journal of Biological Chemistry

Neutral glycolipids of the filamentous fungus Neurospora crassa: altered expression in plant defensin-resistant mutants

scientific article published on 16 January 2005

Non-disulfide-bridged peptides from Tityus serrulatus venom: Evidence for proline-free ACE-inhibitors

scientific article published on 21 May 2016

Novel anti-infective implant substrates: controlled release of antibiofilm compounds from mesoporous silica-containing macroporous titanium

scientific article published on 7 January 2015

Novel fungicidal benzylsulfanyl-phenylguanidines

scientific article published on 24 April 2011

Oral administration of the broad-spectrum antibiofilm compound toremifene inhibits Candida albicans and Staphylococcus aureus biofilm formation in vivo

scientific article

Phytosphingosine-1-phosphate is a signaling molecule involved in miconazole resistance in sessile Candida albicans cells

scientific article published on 21 February 2012

Plant defensins.

scientific article

Plant-derived decapeptide OSIP108 interferes with Candida albicans biofilm formation without affecting cell viability

scientific article

Potentiation of antibiofilm activity of amphotericin B by superoxide dismutase inhibition

scientific article published on September 2013

Protocol for Determination of the Persister Subpopulation in Candida Albicans Biofilms

scientific article

Reactive oxygen species-inducing antifungal agents and their activity against fungal biofilms

scientific article

Regulated Cell Death as a Therapeutic Target for Novel Antifungal Peptides and Biologics.

scientific article

Repurposing AM404 for the treatment of oral infections by Porphyromonas gingivalis.

scientific article published on 7 April 2017

Repurposing Toremifene for Treatment of Oral Bacterial Infections.

scientific article published on 19 December 2016

Repurposing as a means to increase the activity of amphotericin B and caspofungin against Candida albicans biofilms.

scientific article

Repurposing the antidepressant sertraline as SHMT inhibitor to suppress serine/glycine synthesis addicted breast tumor growth

scientific article published on 17 November 2020

Roux-en-y gastric bypass attenuates hepatic mitochondrial dysfunction in mice with non-alcoholic steatohepatitis.

scientific article published on 10 June 2014

SKN1, a novel plant defensin-sensitivity gene in Saccharomyces cerevisiae, is implicated in sphingolipid biosynthesis

scientific article

Skn1 and Ipt1 negatively regulate autophagy in Saccharomyces cerevisiae

scientific article

Specific binding sites for an antifungal plant defensin from Dahlia (Dahlia merckii) on fungal cells are required for antifungal activity

scientific article

Specific, High Affinity Binding Sites for an Antifungal Plant Defensin on Neurospora crassa Hyphae and Microsomal Membranes

scientific article published in Journal of Biological Chemistry

Sphingolipids and mitochondrial function in budding yeast

scientific article published on 25 June 2014

Sphingolipids and mitochondrial function, lessons learned from yeast

scientific article published on 25 June 2014

Stimulation of superoxide production increases fungicidal action of miconazole against Candida albicans biofilms

scientific article published on 07 June 2016

Structure-activity relationship study of the antimicrobial CRAMP-derived peptide CRAMP20-33

scientific article published on 31 August 2018

Structure-activity relationship study of the plant-derived decapeptide OSIP108 inhibiting Candida albicans biofilm formation.

scientific article

Superoxide dismutases are involved in Candida albicans biofilm persistence against miconazole

scientific article

Synergistic Activity of the Plant Defensin HsAFP1 and Caspofungin against Candida albicans Biofilms and Planktonic Cultures

scientific article

Synergistic activity of the tyrocidines, antimicrobial cyclodecapeptides from Bacillus aneurinolyticus, with amphotericin B and caspofungin against Candida albicans biofilms

scientific article

Synthesis and fungicidal activity of 3,5-dichloropyrazin-2(1H)-one derivatives.

scientific article published on 13 June 2009

Synthetic peptides derived from the beta2-beta3 loop of Raphanus sativus antifungal protein 2 that mimic the active site

scientific article

TEMPORARY REMOVAL: The antifungal plant defensin HsAFP1 induces autophagy, vacuolar dysfunction and cell cycle impairment in yeast

scientific article published on 05 March 2020

The Antifungal Activity of RsAFP2, a Plant Defensin from Raphanus sativus , Involves the Induction of Reactive Oxygen Species in Candida albicans

article

The Antifungal Plant Defensin HsAFP1 Is a Phosphatidic Acid-Interacting Peptide Inducing Membrane Permeabilization.

scientific article published on 21 November 2017

The Antifungal Plant Defensin HsAFP1 from Heuchera sanguinea Induces Apoptosis in Candida albicans

scientific article

The Nonsteroidal Antiinflammatory Drug Diclofenac Potentiates the In Vivo Activity of Caspofungin Against Candida albicans Biofilms

scientific article published on 14 September 2012

The antifungal plant defensin AtPDF2.3 from Arabidopsis thaliana blocks potassium channels.

scientific article published on 30 August 2016

The antifungal plant defensin RsAFP2 from radish induces apoptosis in a metacaspase independent way in Candida albicans.

scientific article published on 14 July 2009

The heat-induced molecular disaggregase Hsp104 of Candida albicans plays a role in biofilm formation and pathogenicity in a worm infection model

scientific article published on 25 May 2012

The mode of antifungal action of plant, insect and human defensins

scientific article published on July 2008

The plant decapeptide OSIP108 can alleviate mitochondrial dysfunction induced by cisplatin in human cells.

scientific article published on 19 September 2014

The plant decapeptide OSIP108 prevents copper-induced apoptosis in yeast and human cells

scientific article

The plant decapeptide OSIP108 prevents copper-induced toxicity in various models for Wilson disease

scientific article published on 16 August 2014

The plant defensin RsAFP2 induces cell wall stress, septin mislocalization and accumulation of ceramides in Candida albicans.

scientific article

The protein kinase Sch9 is a key regulator of sphingolipid metabolism in Saccharomyces cerevisiae.

scientific article

The radish defensins RsAFP1 and RsAFP2 act synergistically with caspofungin against Candida albicans biofilms

scientific article

Therapeutic potential of antifungal plant and insect defensins

scientific article published on 04 September 2007

Transcription factor Efg1 contributes to the tolerance of Candida albicans biofilms against antifungal agents in vitro and in vivo

scientific article published on 15 March 2012

Tuning the Surface Interactions between Single Cells and an OSTE+ Microwell Array for Enhanced Single Cell Manipulation

scientific article published on 07 January 2021

Ydc1p ceramidase triggers organelle fragmentation, apoptosis and accelerated ageing in yeast

scientific article published in June 2008

Yeast as a model for the identification of novel survival-promoting compounds applicable to treat degenerative diseases

scientific article

Paulina is supported by:

About Paulina

Help