List of works - Peter C E Moody

A heme-binding domain controls regulation of ATP-dependent potassium channels.

scientific article

A mechanism for CO regulation of ion channels

scientific article published on 2 March 2018

A modulator of rho family G proteins, rhoGDI, binds these G proteins via an immunoglobulin-like domain and a flexible N-terminal arm

scientific article

A protein catalytic framework with an N-terminal nucleophile is capable of self-activation

scientific article

An analysis of substrate binding interactions in the heme peroxidase enzymes: a structural perspective.

scientific article

Analysis and characterization of data from twinned crystals.

scientific article

Atomic resolution structures and solution behavior of enzyme-substrate complexes of Enterobacter cloacae PB2 pentaerythritol tetranitrate reductase. Multiple conformational states and implications for the mechanism of nitroaromatic explosive degrada

scientific article

Author Correction: A mechanism for CO regulation of ion channels

scientific article published in Nature Communications

Combining X-ray and neutron crystallography with spectroscopy

scientific article

Comparison of the regulation, metabolic functions, and roles in virulence of the glyceraldehyde-3-phosphate dehydrogenase homologues gapA and gapB in Staphylococcus aureus

scientific article published on 27 September 2010

Crystal structure of Trematomus newnesi haemoglobin re-opens the root effect question

scientific article

Crystal structure of an extracellular fragment of the rat CD4 receptor containing domains 3 and 4

scientific article published on 01 June 1994

Crystal structure of bacterial morphinone reductase and properties of the C191A mutant enzyme

scientific article

Crystal structure of guaiacol and phenol bound to a heme peroxidase

scientific article

Crystal structure of pentaerythritol tetranitrate reductase: "flipped" binding geometries for steroid substrates in different redox states of the enzyme

scientific article

Crystal structure of the ascorbate peroxidase-ascorbate complex

scientific article (publication date: April 2003)

Crystal structure of the ascorbate peroxidase-salicylhydroxamic acid complex

scientific article published in July 2004

Crystal structure of the human O(6)-alkylguanine-DNA alkyltransferase

scientific article

Crystallization and preliminary diffraction studies of morphinone reductase, a flavoprotein involved in the degradation of morphine alkaloids.

scientific article

Crystallization and preliminary diffraction studies of pentaerythritol tetranitrate reductase from Enterobacter cloacae PB2

scientific article published on 01 July 1998

Crystallization of Inhibited Aspartic Proteinase from Candida albicans

Crystallization of O6-methylguanine-DNA methyltransferase from Escherichia coli

scientific article

DNA-binding mechanism of the Escherichia coli Ada O(6)-alkylguanine-DNA alkyltransferase

scientific article published on October 2000

Direct visualization of a Fe(IV)-OH intermediate in a heme enzyme

scientific article

Discovery of a heme-binding domain in a neuronal voltage-gated potassium channel

scientific article published on 28 July 2020

Effects of environment on flavin reactivity in morphinone reductase: analysis of enzymes displaying differential charge near the N-1 atom and C-2 carbonyl region of the active-site flavin

scientific article

Engineering the substrate specificity and reactivity of a heme protein: creation of an ascorbate binding site in cytochrome c peroxidase

scientific article

Enzyme-catalyzed mechanism of isoniazid activation in class I and class III peroxidases

scientific article

Evidence for heme oxygenase activity in a heme peroxidase

scientific article

Expression, purification, crystallization and preliminary X-ray analysis of an NAD-dependent glyceraldehyde-3-phosphate dehydrogenase from Helicobacter pylori

scientific article published on 26 July 2008

Expression, purification, crystallization and preliminary X-ray analysis of an NADP-dependent glyceraldehyde-3-phosphate dehydrogenase from Helicobacter pylori

scientific article

Expression, purification, crystallization and preliminary X-ray analysis of wild-type and of an active-site mutant of glyceraldehyde-3-phosphate dehydrogenase from Campylobacter jejuni

scientific article published on 22 December 2010

Filling a hole in cytochrome P450 BM3 improves substrate binding and catalytic efficiency

scientific article

Heme binding to human CLOCK affects interactions with the E-box

scientific article published on 16 September 2019

Heme enzymes. Neutron cryo-crystallography captures the protonation state of ferryl heme in a peroxidase

scientific article

How is the distal pocket of a heme protein optimized for binding of tryptophan?

scientific article published on 22 November 2012

Interaction of ascorbate peroxidase with substrates: a mechanistic and structural analysis

scientific article

Iron oxidation state modulates active site structure in a heme peroxidase

scientific article

Kinetic and structural basis of reactivity of pentaerythritol tetranitrate reductase with NADPH, 2-cyclohexenone, nitroesters, and nitroaromatic explosives

scientific article

Ligand-induced conformational change in penicillin acylase

scientific article

Molecular basis of sugar recognition by collectin-K1 and the effects of mutations associated with 3MC syndrome

scientific article published on 17 April 2015

Nature of the Ferryl Heme in Compounds I and II

scientific article

Nature of the ferryl heme in Compounds I and II.

scientific article published in May 2011

Penicillin acylase has a single-amino-acid catalytic centre

scientific article

Probing the conformational mobility of the active site of a heme peroxidase

scientific article

Proton delivery to ferryl heme in a heme peroxidase: enzymatic use of the Grotthuss mechanism

scientific article

Redox-linked domain movements in the catalytic cycle of cytochrome p450 reductase

scientific article published on August 2013

Reductive and oxidative half-reactions of morphinone reductase from Pseudomonas putida M10: a kinetic and thermodynamic analysis

scientific article published on 01 May 1998

Reply to Mortensen et al.: The zymogen form of complement component C1

scientific article published on 13 April 2018

Serine acetyltransferase from Escherichia coli is a dimer of trimers

scientific article published on 01 January 2000

Structural basis of mannan-binding lectin recognition by its associated serine protease MASP-1: implications for complement activation

scientific article

Structural basis of the C1q/C1s interaction and its central role in assembly of the C1 complex of complement activation

scientific article

Structure of Cu(I)-bound DJ-1 reveals a biscysteinate metal binding site at the homodimer interface: insights into mutational inactivation of DJ-1 in Parkinsonism

scientific article

Structure of holo-glyceraldehyde-3-phosphate dehydrogenase from Bacillus stearothermophilus at 1.8 A resolution

scientific article

Structure of the C1r-C1s interaction of the C1 complex of complement activation

scientific article published on 8 January 2018

The Crystal Structure of Pneumolysin at 2.0 Å Resolution Reveals the Molecular Packing of the Pre-pore Complex

scientific article published on 3 September 2015

The Nature and Reactivity of Ferryl Heme in Compounds I and II.

scientific article published on 12 January 2018

The Redox Properties of Ascorbate Peroxidase†

scientific article published on 20 June 2007

The crystal structure of a major secreted aspartic proteinase from Candida albicans in complexes with two inhibitors

scientific article

The high-resolution crystal structure of a parallel-stranded guanine tetraplex

scientific article

The potential role of glycine-160 of human O6-alkylguanine-DNA alkyltransferase in reaction with O6-benzylguanine as determined by site-directed mutagenesis and molecular modelling comparisons

scientific article published in September 1997

The rise of neutron cryo-crystallography

The role of Ala134 in controlling substrate binding and reactivity in ascorbate peroxidase

scientific article published on 29 December 2017

The role of serine 167 in human indoleamine 2,3-dioxygenase: a comparison with tryptophan 2,3-dioxygenase

scientific article published on 28 March 2008

The structure and mechanism of serine acetyltransferase from Escherichia coli

scientific article

The structure of the exo-beta-(1,3)-glucanase from Candida albicans in native and bound forms: relationship between a pocket and groove in family 5 glycosyl hydrolases

scientific article

The tuberculosis prodrug isoniazid bound to activating peroxidases

scientific article

Visualizing the protons in a metalloenzyme electron proton transfer pathway

scientific article published on 09 March 2020

X-ray crystallographic studies on hexameric insulins in the presence of helix-stabilizing agents, thiocyanate, methylparaben, and phenol

scientific article

List of works by Peter C E Moody

A heme-binding domain controls regulation of ATP-dependent potassium channels.

A mechanism for CO regulation of ion channels

A modulator of rho family G proteins, rhoGDI, binds these G proteins via an immunoglobulin-like domain and a flexible N-terminal arm

A protein catalytic framework with an N-terminal nucleophile is capable of self-activation

An analysis of substrate binding interactions in the heme peroxidase enzymes: a structural perspective.

Analysis and characterization of data from twinned crystals.

Atomic resolution structures and solution behavior of enzyme-substrate complexes of Enterobacter cloacae PB2 pentaerythritol tetranitrate reductase. Multiple conformational states and implications for the mechanism of nitroaromatic explosive degrada

Author Correction: A mechanism for CO regulation of ion channels

Combining X-ray and neutron crystallography with spectroscopy

Comparison of the regulation, metabolic functions, and roles in virulence of the glyceraldehyde-3-phosphate dehydrogenase homologues gapA and gapB in Staphylococcus aureus

Crystal structure of Trematomus newnesi haemoglobin re-opens the root effect question

Crystal structure of an extracellular fragment of the rat CD4 receptor containing domains 3 and 4

Crystal structure of bacterial morphinone reductase and properties of the C191A mutant enzyme

Crystal structure of guaiacol and phenol bound to a heme peroxidase

Crystal structure of pentaerythritol tetranitrate reductase: "flipped" binding geometries for steroid substrates in different redox states of the enzyme

Crystal structure of the ascorbate peroxidase-ascorbate complex

Crystal structure of the ascorbate peroxidase-salicylhydroxamic acid complex

Crystal structure of the human O(6)-alkylguanine-DNA alkyltransferase

Crystallization and preliminary diffraction studies of morphinone reductase, a flavoprotein involved in the degradation of morphine alkaloids.

Crystallization and preliminary diffraction studies of pentaerythritol tetranitrate reductase from Enterobacter cloacae PB2

Crystallization of Inhibited Aspartic Proteinase from Candida albicans

Crystallization of O6-methylguanine-DNA methyltransferase from Escherichia coli

DNA-binding mechanism of the Escherichia coli Ada O(6)-alkylguanine-DNA alkyltransferase

Direct visualization of a Fe(IV)-OH intermediate in a heme enzyme

Discovery of a heme-binding domain in a neuronal voltage-gated potassium channel

Effects of environment on flavin reactivity in morphinone reductase: analysis of enzymes displaying differential charge near the N-1 atom and C-2 carbonyl region of the active-site flavin

Engineering the substrate specificity and reactivity of a heme protein: creation of an ascorbate binding site in cytochrome c peroxidase

Enzyme-catalyzed mechanism of isoniazid activation in class I and class III peroxidases

Evidence for heme oxygenase activity in a heme peroxidase

Expression, purification, crystallization and preliminary X-ray analysis of an NAD-dependent glyceraldehyde-3-phosphate dehydrogenase from Helicobacter pylori

Expression, purification, crystallization and preliminary X-ray analysis of an NADP-dependent glyceraldehyde-3-phosphate dehydrogenase from Helicobacter pylori

Expression, purification, crystallization and preliminary X-ray analysis of wild-type and of an active-site mutant of glyceraldehyde-3-phosphate dehydrogenase from Campylobacter jejuni

Filling a hole in cytochrome P450 BM3 improves substrate binding and catalytic efficiency

Heme binding to human CLOCK affects interactions with the E-box

Heme enzymes. Neutron cryo-crystallography captures the protonation state of ferryl heme in a peroxidase

How is the distal pocket of a heme protein optimized for binding of tryptophan?

Interaction of ascorbate peroxidase with substrates: a mechanistic and structural analysis

Iron oxidation state modulates active site structure in a heme peroxidase

Kinetic and structural basis of reactivity of pentaerythritol tetranitrate reductase with NADPH, 2-cyclohexenone, nitroesters, and nitroaromatic explosives

Ligand-induced conformational change in penicillin acylase

Molecular basis of sugar recognition by collectin-K1 and the effects of mutations associated with 3MC syndrome

Nature of the Ferryl Heme in Compounds I and II

Nature of the ferryl heme in Compounds I and II.

Penicillin acylase has a single-amino-acid catalytic centre

Probing the conformational mobility of the active site of a heme peroxidase

Proton delivery to ferryl heme in a heme peroxidase: enzymatic use of the Grotthuss mechanism

Redox-linked domain movements in the catalytic cycle of cytochrome p450 reductase

Reductive and oxidative half-reactions of morphinone reductase from Pseudomonas putida M10: a kinetic and thermodynamic analysis

Reply to Mortensen et al.: The zymogen form of complement component C1

Serine acetyltransferase from Escherichia coli is a dimer of trimers

Structural basis of mannan-binding lectin recognition by its associated serine protease MASP-1: implications for complement activation

Structural basis of the C1q/C1s interaction and its central role in assembly of the C1 complex of complement activation

Structure of Cu(I)-bound DJ-1 reveals a biscysteinate metal binding site at the homodimer interface: insights into mutational inactivation of DJ-1 in Parkinsonism

Structure of holo-glyceraldehyde-3-phosphate dehydrogenase from Bacillus stearothermophilus at 1.8 A resolution

Structure of the C1r-C1s interaction of the C1 complex of complement activation

The Crystal Structure of Pneumolysin at 2.0 Å Resolution Reveals the Molecular Packing of the Pre-pore Complex

The Nature and Reactivity of Ferryl Heme in Compounds I and II.

The Redox Properties of Ascorbate Peroxidase†

The crystal structure of a major secreted aspartic proteinase from Candida albicans in complexes with two inhibitors

The high-resolution crystal structure of a parallel-stranded guanine tetraplex

The potential role of glycine-160 of human O6-alkylguanine-DNA alkyltransferase in reaction with O6-benzylguanine as determined by site-directed mutagenesis and molecular modelling comparisons

The rise of neutron cryo-crystallography

The role of Ala134 in controlling substrate binding and reactivity in ascorbate peroxidase

The role of serine 167 in human indoleamine 2,3-dioxygenase: a comparison with tryptophan 2,3-dioxygenase

The structure and mechanism of serine acetyltransferase from Escherichia coli

The structure of the exo-beta-(1,3)-glucanase from Candida albicans in native and bound forms: relationship between a pocket and groove in family 5 glycosyl hydrolases

The tuberculosis prodrug isoniazid bound to activating peroxidases

Visualizing the protons in a metalloenzyme electron proton transfer pathway

X-ray crystallographic studies on hexameric insulins in the presence of helix-stabilizing agents, thiocyanate, methylparaben, and phenol