List of works by Leng Han

A ROR1-HER3-lncRNA signalling axis modulates the Hippo-YAP pathway to regulate bone metastasis.

scientific article published on 23 January 2017

Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells

scientific article

Advanced Datamining Using RNAseq Data

scholarly article

Advances in computational genomics

scientific article published on 6 January 2015

Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2

article

Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2.

scientific article

Alternative applications for distinct RNA sequencing strategies

scientific article

An SVM-Based Algorithm for Classifying Promoter-Associated CpG Islands in the Human and Mouse Genomes

Assessing the clinical utility of cancer genomic and proteomic data across tumor types.

scientific article

Author Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers

scientific article published on 27 April 2020

CSCD2: an integrated interactional database of cancer-specific circular RNAs

scientific article published on 01 January 2022

Characterization of the dual functional effects of heat shock proteins (HSPs) in cancer hallmarks to aid development of HSP inhibitors

scientific article published on 23 November 2020

Circular RNAs as promising biomarkers in cancer: detection, function, and beyond

scientific article published on 20 March 2019

Comparative analysis of CpG islands in four fish genomes

scientific article

Comprehensive characterization of circular RNAs in ~ 1000 human cancer cell lines

scientific article published on 26 August 2019

Comprehensive molecular characterization of mitochondrial genomes in human cancers

scientific article published on 05 February 2020

Conservation and divergence of DNA methylation in eukaryotes: new insights from single base-resolution DNA methylomes

scientific article published on February 2011

Contrast features of CpG islands in the promoter and other regions in the dog genome

scientific article published on 03 May 2009

CpG island density and its correlations with genomic features in mammalian genomes

scientific article published on 13 May 2008

CpG islands or CpG clusters: how to identify functional GC-rich regions in a genome?

scientific article

CpG islands: algorithms and applications in methylation studies

scientific article

Dissecting the molecular relationship among various cardiogenic progenitor cells

scientific article published on 5 March 2013

Early stem cell engraftment predicts late cardiac functional recovery: preclinical insights from molecular imaging

scientific article

Effective combinatorial immunotherapy for penile squamous cell carcinoma

scientific article published on 01 May 2020

Efficient gene delivery of primary human cells using peptide linked polyethylenimine polymer hybrid

scientific article published on 8 April 2011

Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tumor development

scientific article published on 4 October 2017

Erythrocytes retain hypoxic adenosine response for faster acclimatization upon re-ascent

scientific article published on 07 February 2017

Escherichia coli Metabolite Profiling Leads to the Development of an RNA Interference Strain for Caenorhabditis elegans

scientific article published on 07 January 2020

Features and trend of loss of promoter-associated CpG islands in the human and mouse genomes

scientific article

Features of methylation and gene expression in the promoter-associated CpG islands using human methylome data

scientific article

Finding the lost treasures in exome sequencing data

scientific article

Gene co-expression network analysis reveals common system-level properties of prognostic genes across cancer types

scientific article published on January 2014

Gene- and evidence-based candidate gene selection for schizophrenia and gene feature analysis

scientific article

Genome-Wide DNA Methylation Profiling in 40 Breast Cancer Cell Lines

Global analysis of tRNA and translation factor expression reveals a dynamic landscape of translational regulation in human cancers

scientific article published on 21 December 2018

INO80 facilitates pluripotency gene activation in embryonic stem cell self-renewal, reprogramming, and blastocyst development

scientific article

INO80 governs superenhancer-mediated oncogenic transcription and tumor growth in melanoma

scientific article published on June 2016

Integrated genomic analysis of recurrence-associated small non-coding RNAs in oesophageal cancer

scientific article published on 9 August 2016

LNCediting: a database for functional effects of RNA editing in lncRNAs

scientific article published on 19 September 2016

LncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stress

scientific article

Methylation of promoters of microRNAs and their host genes in myelodysplastic syndromes.

scientific article published on 15 May 2013

MicroRNA-302 increases reprogramming efficiency via repression of NR2F2.

scientific article

Microfluidic single-cell analysis shows that porcine induced pluripotent stem cell-derived endothelial cells improve myocardial function by paracrine activation

scientific article

Mining diverse small RNA species in the deep transcriptome

scientific article

Multi-omics prediction of immune-related adverse events during checkpoint immunotherapy

scientific article published on 02 October 2020

Nobiletin fortifies mitochondrial respiration in skeletal muscle to promote healthy aging against metabolic challenge

scientific article published on 28 August 2019

Oncogenic lncRNA downregulates cancer cell antigen presentation and intrinsic tumor suppression

scientific article published on 03 June 2019

Pathway and Network Analysis of Schizophrenia Candidate Genes under Meta-Analysis Linkage Peaks

article

Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy.

scientific article

Preclinical derivation and imaging of autologously transplanted canine induced pluripotent stem cells

scientific article published on 30 June 2011

Publisher Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers

scientific article published on 11 February 2020

Publisher Correction: Transcribed ultraconserved region 339 promotes carcinogenesis by modulating tumor suppressor microRNAs

scientific article published on 8 January 2018

RNA editing derived epitopes function as cancer antigens to elicit immune responses

scientific article published in Nature Communications

Safe genetic modification of cardiac stem cells using a site-specific integration technique

scientific article

Schizophrenia Genes: Characteristics of Function and Protein Interaction Networks

article

Sex-associated molecular differences for cancer immunotherapy

scientific article published on 14 April 2020

Single-cell analysis of murine fibroblasts identifies neonatal to adult switching that regulates cardiomyocyte maturation

scientific article published on 22 May 2020

Single-cell and spatial analysis reveal interaction of FAP<sup>+</sup> fibroblasts and SPP1<sup>+</sup> macrophages in colorectal cancer

scientific article published on 01 April 2022

Single-cell reconstruction of differentiation trajectory reveals a critical role of ETS1 in human cardiac lineage commitment

scientific article published on 13 November 2019

Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function

scientific article published on 08 January 2020

Small-molecule MMP2/MMP9 inhibitor SB-3CT modulates tumor immune surveillance by regulating PD-L1

scientific article published on 28 September 2020

Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease

scientific article published on 10 November 2017

Systematic prioritization and integrative analysis of copy number variations in schizophrenia reveal key schizophrenia susceptibility genes

scientific article

TANRIC: An Interactive Open Platform to Explore the Function of lncRNAs in Cancer

scientific article

TRIM59 promotes breast cancer motility by suppressing p62-selective autophagic degradation of PDCD10

scientific article published on 08 November 2018

Targeting Glucose Metabolism Sensitizes Pancreatic Cancer to MEK Inhibition

scientific article published on 11 June 2021

The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers

scientific article

The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer

scientific journal article

The LINK-A lncRNA interacts with PtdIns(3,4,5)P3 to hyperactivate AKT and confer resistance to AKT inhibitors

scientific article published on 20 February 2017

The Pan-Cancer analysis of pseudogene expression reveals biologically and clinically relevant tumour subtypes

scientific article

The THO complex regulates pluripotency gene mRNA export and controls embryonic stem cell self-renewal and somatic cell reprogramming

scientific journal article

The genetic and pharmacogenomic landscape of snoRNAs in human cancer

scientific article published on 23 June 2020

The lncRNA H19 alleviates muscular dystrophy by stabilizing dystrophin

scientific article published on 26 October 2020

Transcribed ultraconserved region 339 promotes carcinogenesis by modulating tumor suppressor microRNAs.

scientific article published on 27 November 2017

Transcriptional landscape and clinical utility of enhancer RNAs for eRNA-targeted therapy in cancer

scientific article published on 08 October 2019

Variable activation of the DNA damage response pathways in patients undergoing single-photon emission computed tomography myocardial perfusion imaging

scientific article

p53-dependent autophagic degradation of TET2 modulates cancer therapeutic resistance

scientific article published on 02 November 2018

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