List of works - Rafael Giraldo

A DNA-promoted amyloid proteinopathy in Escherichia coli

scientific article published on 30 July 2010

A conformational switch between transcriptional repression and replication initiation in the RepA dimerization domain

scientific article published on 01 July 2003

Aggregation interplay between variants of the RepA-WH1 prionoid in Escherichia coli

scientific article published on 2 May 2014

Amyloid assemblies: protein legos at a crossroads in bottom-up synthetic biology

scientific article published on November 22, 2010

An intrinsic 5'-deoxyribose-5-phosphate lyase activity in DNA polymerase beta from Leishmania infantum supports a role in DNA repair

scientific article published on 19 September 2005

Antithrombin Murcia (K241E) causing antithrombin deficiency: a possible role for altered glycosylation

scientific article

Bacterial zipper

scientific article published in Nature

Binding of sulphonated indigo derivatives to RepA-WH1 inhibits DNA-induced protein amyloidogenesis

scientific article published on 19 February 2008

Common domains in the initiators of DNA replication in Bacteria, Archaea and Eukarya: combined structural, functional and phylogenetic perspectives.

scientific article

Conformational Priming of RepA-WH1 for Functional Amyloid Conversion Detected by NMR Spectroscopy

scientific article published on 06 January 2020

Crystallization and preliminary X-ray crystallographic studies on the parD-encoded protein Kid from Escherichia coli plasmid R1

scientific article published on 24 January 2002

Differential binding of wild-type and a mutant RepA protein to oriR sequence suggests a model for the initiation of plasmid R1 replication

scientific article published on 01 December 1992

Direct assessment in bacteria of prionoid propagation and phenotype selection by Hsp70 chaperone

scientific article published on 9 February 2014

Early events in the binding of the pPS10 replication protein RepA to single iteron and operator DNA sequences.

scientific article

Engineered bacterial hydrophobic oligopeptide repeats in a synthetic yeast prion, [REP-PSI (+)].

scientific article

Fluorescence studies of the replication initiator protein RepA in complex with operator and iteron sequences and free in solution.

scientific article

Functional amyloids as inhibitors of plasmid DNA replication

scientific article published on 5 May 2016

Functional interactions between homologous conditional killer systems of plasmid and chromosomal origin

scientific article published on 01 July 1997

Genetic and functional analysis of the basic replicon of pPS10, a plasmid specific for Pseudomonas isolated from Pseudomonas syringae patovar savastanoi.

scientific article published in January 1992

Imaging the asymmetrical DNA bend induced by repressor activator protein 1 with scanning tunneling microscopy

scientific article published on 01 July 1994

Intercellular Transmission of a Synthetic Bacterial Cytotoxic Prion-Like Protein in Mammalian Cells

scientific article published on 14 April 2020

Negative regulation of pPS10 plasmid replication: origin pairing by zipping-up DNA-bound RepA monomers

scientific article published on 19 February 2008

Non-cytotoxic variants of the Kid protein that retain their auto-regulatory activity

scientific article published in September 2003

Nucleation of Amyloid Oligomers by RepA-WH1-Prionoid-Functionalized Gold Nanorods

scientific article published on 4 August 2016

Pre-amyloid oligomers of the proteotoxic RepA-WH1 prionoid assemble at the bacterial nucleoid

scientific article

Promotion of parallel DNA quadruplexes by a yeast telomere binding protein: a circular dichroism study.

scientific article published on August 1994

Protein domains and conformational changes in the activation of RepA, a DNA replication initiator

scientific article

RepA-WH1 prionoid: Clues from bacteria on factors governing phase transitions in amyloidogenesis.

scientific article

RepA-WH1 prionoid: a synthetic amyloid proteinopathy in a minimalist host

scientific article published on April 2011

RepA-WH1, the agent of an amyloid proteinopathy in bacteria, builds oligomeric pores through lipid vesicles.

scientific article

Self assembly of human septin 2 into amyloid filaments

scientific article published on 28 September 2011

Structural analysis of the interactions between hsp70 chaperones and the yeast DNA replication protein Orc4p.

scientific article

Structural changes in RepA, a plasmid replication initiator, upon binding to origin DNA.

scientific article published on 7 March 2003

Structural characterization of microcin E492 amyloid formation: Identification of the precursors

scientific article published on 07 March 2012

SynBio and the Boundaries between Functional and Pathogenic RepA-WH1 Bacterial Amyloids

scientific article published on 30 June 2020

Telomere structure and function

scientific article

Transcription of repA, the gene of the initiation protein of the Pseudomonas plasmid pPS10, is autoregulated by interactions of the RepA protein at a symmetrical operator.

scientific article

List of works by Rafael Giraldo

A DNA-promoted amyloid proteinopathy in Escherichia coli

A conformational switch between transcriptional repression and replication initiation in the RepA dimerization domain

Aggregation interplay between variants of the RepA-WH1 prionoid in Escherichia coli

Amyloid assemblies: protein legos at a crossroads in bottom-up synthetic biology

An intrinsic 5'-deoxyribose-5-phosphate lyase activity in DNA polymerase beta from Leishmania infantum supports a role in DNA repair

Antithrombin Murcia (K241E) causing antithrombin deficiency: a possible role for altered glycosylation

Bacterial zipper

Binding of sulphonated indigo derivatives to RepA-WH1 inhibits DNA-induced protein amyloidogenesis

Common domains in the initiators of DNA replication in Bacteria, Archaea and Eukarya: combined structural, functional and phylogenetic perspectives.

Conformational Priming of RepA-WH1 for Functional Amyloid Conversion Detected by NMR Spectroscopy

Crystallization and preliminary X-ray crystallographic studies on the parD-encoded protein Kid from Escherichia coli plasmid R1

Differential binding of wild-type and a mutant RepA protein to oriR sequence suggests a model for the initiation of plasmid R1 replication

Direct assessment in bacteria of prionoid propagation and phenotype selection by Hsp70 chaperone

Early events in the binding of the pPS10 replication protein RepA to single iteron and operator DNA sequences.

Engineered bacterial hydrophobic oligopeptide repeats in a synthetic yeast prion, [REP-PSI (+)].

Fluorescence studies of the replication initiator protein RepA in complex with operator and iteron sequences and free in solution.

Functional amyloids as inhibitors of plasmid DNA replication

Functional interactions between homologous conditional killer systems of plasmid and chromosomal origin

Genetic and functional analysis of the basic replicon of pPS10, a plasmid specific for Pseudomonas isolated from Pseudomonas syringae patovar savastanoi.

Imaging the asymmetrical DNA bend induced by repressor activator protein 1 with scanning tunneling microscopy

Intercellular Transmission of a Synthetic Bacterial Cytotoxic Prion-Like Protein in Mammalian Cells

Negative regulation of pPS10 plasmid replication: origin pairing by zipping-up DNA-bound RepA monomers

Non-cytotoxic variants of the Kid protein that retain their auto-regulatory activity

Nucleation of Amyloid Oligomers by RepA-WH1-Prionoid-Functionalized Gold Nanorods

Pre-amyloid oligomers of the proteotoxic RepA-WH1 prionoid assemble at the bacterial nucleoid

Promotion of parallel DNA quadruplexes by a yeast telomere binding protein: a circular dichroism study.

Protein domains and conformational changes in the activation of RepA, a DNA replication initiator

RepA-WH1 prionoid: Clues from bacteria on factors governing phase transitions in amyloidogenesis.

RepA-WH1 prionoid: a synthetic amyloid proteinopathy in a minimalist host

RepA-WH1, the agent of an amyloid proteinopathy in bacteria, builds oligomeric pores through lipid vesicles.

Self assembly of human septin 2 into amyloid filaments

Structural analysis of the interactions between hsp70 chaperones and the yeast DNA replication protein Orc4p.

Structural changes in RepA, a plasmid replication initiator, upon binding to origin DNA.

Structural characterization of microcin E492 amyloid formation: Identification of the precursors

SynBio and the Boundaries between Functional and Pathogenic RepA-WH1 Bacterial Amyloids

Telomere structure and function

Transcription of repA, the gene of the initiation protein of the Pseudomonas plasmid pPS10, is autoregulated by interactions of the RepA protein at a symmetrical operator.