List of works - José Antonio Bengoechea

2-Hydroxylation of Lipid A Contributes to Virulence

scientific article published on 25 March 2019

A Klebsiella pneumoniae antibiotic resistance mechanism that subdues host defences and promotes virulence

scientific article published on 15 February 2017

A Porcine Ex Vivo Lung Perfusion Model To Investigate Bacterial Pathogenesis

scientific article published on 03 December 2019

An unbiased genetic screen reveals the polygenic nature of the influenza virus anti-interferon response.

scientific article

Analysis of the networks controlling the antimicrobial-peptide-dependent induction of Klebsiella pneumoniae virulence factors

scientific article

Apoptosis, Toll-like, RIG-I-like and NOD-like Receptors Are Pathways Jointly Induced by Diverse Respiratory Bacterial and Viral Pathogens

scientific article published on March 2017

Bactericidal activity of Lys49 and Asp49 myotoxic phospholipases A2 from Bothrops asper snake venom--synthetic Lys49 myotoxin II-(115-129)-peptide identifies its bactericidal region

scientific article published in April 1998

Brucella abortus and its closest phylogenetic relative, Ochrobactrum spp., differ in outer membrane permeability and cationic peptide resistance

scientific article published on June 2000

Capsule polysaccharide is a bacterial decoy for antimicrobial peptides

scientific article

Capsule polysaccharide mediates bacterial resistance to antimicrobial peptides

scientific article

Characterization and biological role of the O-polysaccharide gene cluster of Yersinia enterocolitica serotype O:9

scientific article

Characterization of nontypable Haemophilus influenzae isolates recovered from adult patients with underlying chronic lung disease reveals genotypic and phenotypic traits associated with persistent infection.

scientific article

Characterization of the six glycosyltransferases involved in the biosynthesis of Yersinia enterocolitica serotype O:3 lipopolysaccharide outer core

scientific article published on July 2010

Chronic obstructive pulmonary disease Th1 cells display impaired response to endotoxin

scientific article published on 01 January 2011

Clearance of intracellular Klebsiella pneumoniae infection using gentamicin-loaded nanoparticles

scientific article

Comparative analysis of Klebsiella pneumoniae genomes identifies a phospholipase D family protein as a novel virulence factor

scientific article

Complement factor H is a serum-binding protein for adrenomedullin, and the resulting complex modulates the bioactivities of both partners

scientific article

Control of Klebsiella pneumoniae Infection in Mice by Using Dissolving Microarray Patches Containing Gentamicin

scientific article published on 25 April 2019

Correction: Elucidation of the RamA Regulon in Klebsiella pneumoniae Reveals a Role in LPS Regulation

scientific article published on 11 May 2016

Deciphering the acylation pattern of Yersinia enterocolitica lipid A.

scientific article

Deciphering tissue-induced Klebsiella pneumoniae lipid A structure.

scientific article

Defective B cell response to TLR9 ligand (CpG-ODN), Streptococcus pneumoniae and Haemophilus influenzae extracts in common variable immunodeficiency patients

scientific article published on 25 January 2010

Dissection of host cell signal transduction during Acinetobacter baumannii-triggered inflammatory response

scientific article

Efficacy of cecropin A-melittin peptides on a sepsis model of infection by pan-resistant Acinetobacter baumannii

article

Electronic cigarette vapour increases virulence and inflammatory potential of respiratory pathogens

scientific article published on 18 December 2019

Elucidation of the RamA regulon in Klebsiella pneumoniae reveals a role in LPS regulation

scientific article

Evidence for a non-replicative intracellular stage of nontypable Haemophilus influenzae in epithelial cells.

scientific article

Evolution of colistin resistance in the Klebsiella pneumoniae complex follows multiple evolutionary trajectories with variable effects on fitness and virulence characteristics

scientific article published on 02 November 2020

Experimental pig yersiniosis to assess attenuation of Yersinia enterocolitica O:8 mutant strains.

scientific article published on August 2006

Expression of Toll-like receptor 2 is up-regulated in monocytes from patients with chronic obstructive pulmonary disease

scientific article published on 10 April 2006

Expression of the Yersinia enterocolitica pYV-encoded type III secretion system is modulated by lipopolysaccharide O-antigen status

scientific article published on 18 December 2006

Expression of toll-like receptors 2 and 4 is upregulated during hospital admission in traumatic patients: lack of correlation with blunted innate immune responses

scientific article published on 01 March 2010

Functional Genomic Screen Identifies Klebsiella pneumoniae Factors Implicated in Blocking Nuclear Factor κB (NF-κB) Signaling

scientific article published on 13 May 2015

Functional characterization of Gne (UDP-N-acetylglucosamine-4-epimerase), Wzz (chain length determinant), and Wzy (O-antigen polymerase) of Yersinia enterocolitica serotype O:8

scientific article

Functional genomics to identify therapeutic prophylactic targets.

scientific article published on 19 August 2009

Generation of replication-proficient influenza virus NS1 point mutants with interferon-hyperinducer phenotype.

scientific article

Genome Expression Profiling-Based Identification and Administration Efficacy of Host-Directed Antimicrobial Drugs against Respiratory Infection by Nontypeable Haemophilus influenzae.

scientific article published on 28 September 2015

Genotypic and phenotypic diversity of the noncapsulated Haemophilus influenzae: adaptation and pathogenesis in the human airways.

scientific article published on December 2012

Glutamine as a modulator of the immune system of critical care patients: effect on Toll-like receptor expression. A preliminary study

scientific article

Host cell kinases, α5 and β1 integrins, and Rac1 signalling on the microtubule cytoskeleton are important for non-typable Haemophilus influenzae invasion of respiratory epithelial cells

scientific article

Identification and Characterization of Two Klebsiella pneumoniae lpxL Lipid A Late Acyltransferases and Their Role in Virulence

scientific article published on 26 June 2017

Identification of lptA, lpxE, and lpxO, Three Genes Involved in the Remodeling of Brucella Cell Envelope.

scientific article published in January 2017

Identification of the lipopolysaccharide core of Yersinia pestis and Yersinia pseudotuberculosis as the receptor for bacteriophage φA1122.

scientific article published on 15 July 2011

Impact of cigarette smoke exposure on host-bacterial pathogen interactions.

scientific article published on 07 July 2011

Infection systems biology: from reactive to proactive (P4) medicine

scientific article published on June 1, 2012

Investigating intracellular persistence of Staphylococcus aureus within a murine alveolar macrophage cell line.

scientific article

Klebsiella pneumoniae AcrAB efflux pump contributes to antimicrobial resistance and virulence

scientific article

Klebsiella pneumoniae Capsule Polysaccharide Impedes the Expression of ?-Defensins by Airway Epithelial Cells.

scientific article

Klebsiella pneumoniae OmpA confers resistance to antimicrobial peptides

scientific article published on 17 November 2008

Klebsiella pneumoniae Reduces SUMOylation To Limit Host Defense Responses

scientific article published on 29 September 2020

Klebsiella pneumoniae capsule polysaccharide impedes the expression of beta-defensins by airway epithelial cells

scientific article

Klebsiella pneumoniae increases the levels of Toll-like receptors 2 and 4 in human airway epithelial cells

scientific article

Klebsiella pneumoniae infection biology: living to counteract host defences

scientific article published on 01 March 2019

Klebsiella pneumoniae outer membrane protein A is required to prevent the activation of airway epithelial cells.

scientific article

Klebsiella pneumoniae subverts the activation of inflammatory responses in a NOD1-dependent manner.

scientific article published on 14 October 2010

Klebsiella pneumoniae survives within macrophages by avoiding delivery to lysosomes

scientific article published on 4 June 2015

Klebsiella pneumoniae targets an EGF receptor-dependent pathway to subvert inflammation.

scientific article published on 17 February 2013

Klebsiella pneumoniae triggers a cytotoxic effect on airway epithelial cells

scientific article

Klebsiella pneumoniae type VI secretion system-mediated microbial competition is PhoPQ controlled and reactive oxygen species dependent

scientific article published on 19 March 2020

Klebsiella sweet deadly kiss.

scientific article published on 22 June 2016

Lack of effect of glutamine administration to boost the innate immune system response in trauma patients in the intensive care unit

scientific article published on 24 December 2010

Lipopolysaccharide O antigen status of Yersinia enterocolitica O:8 is essential for virulence and absence of O antigen affects the expression of other Yersinia virulence factors

scientific article published on April 2004

Lipopolysaccharide-binding protein and CD14 are increased in the bronchoalveolar lavage fluid of smokers

scientific article

Modeling Klebsiella pneumoniae pathogenesis by infection of the wax moth Galleria mellonella.

scientific article published on 08 July 2013

Modulation of Haemophilus influenzae interaction with hydrophobic molecules by the VacJ/MlaA lipoprotein impacts strongly on its interplay with the airways.

scientific article published on 2 May 2018

Molecular basis of Yersinia enterocolitica temperature-dependent resistance to antimicrobial peptides.

scientific article published on 13 April 2012

Molecular evolution of proadrenomedullin N-terminal 20 peptide (PAMP): evidence for gene co-option

scientific article published on 30 March 2006

Nanodelivery strategies for the treatment of multidrug-resistant bacterial infections

scientific article published on 04 September 2018

Natural killer cell-intrinsic type I IFN signaling controls Klebsiella pneumoniae growth during lung infection.

scientific article published on 7 November 2017

Nontypable Haemophilus influenzae displays a prevalent surface structure molecular pattern in clinical isolates.

scientific article

Nontypeable Haemophilus influenzae clearance by alveolar macrophages is impaired by exposure to cigarette smoke

scientific article

Outer membrane differences between pathogenic and environmental Yersinia enterocolitica biogroups probed with hydrophobic permeants and polycationic peptides

scientific article

PYHIN1 regulates pro-inflammatory cytokine induction rather than innate immune DNA sensing in airway epithelial cells

scientific article published on 26 February 2020

Pathogenic Yersinia enterocolitica strains increase the outer membrane permeability in response to environmental stimuli by modulating lipopolysaccharide fluidity and lipid A structure

scientific article

Phosphoethanolamine modification of lipid A in colistin-resistant variants of Acinetobacter baumannii mediated by the pmrAB two-component regulatory system.

scientific article

Proper expression of the O-antigen of lipopolysaccharide is essential for the virulence of Yersinia enterocolitica O:8 in experimental oral infection of rabbits

scientific article published on September 2003

Quinolones sensitize gram-negative bacteria to antimicrobial peptides

scientific article published on July 2006

Regulatory network of lipopolysaccharide O-antigen biosynthesis in Yersinia enterocolitica includes cell envelope-dependent signals

scientific article published on May 2002

Relationship between azithromycin susceptibility and administration efficacy for nontypeable Haemophilus influenzae respiratory infection

scientific article

Relative Contribution of P5 and Hap Surface Proteins to Nontypable Haemophilus influenzae Interplay with the Host Upper and Lower Airways

scientific article

Relative contributions of lipooligosaccharide inner and outer core modifications to nontypeable Haemophilus influenzae pathogenesis.

scientific article published on 26 August 2013

Role of bacterial surface structures on the interaction of Klebsiella pneumoniae with phagocytes

scientific article

Role of lipid A acylation in Yersinia enterocolitica virulence

scientific article published on 12 April 2010

Secretory IgA and COPD: A New Kid on the Block? ⬇️

scientific article published on 01 August 2011

Several Hfq-dependent alterations in physiology of Yersinia enterocolitica O:3 are mediated by derepression of the transcriptional regulator RovM.

scientific article published on 23 December 2016

Significance of tagI and mfd genes in the virulence of non-typeable Haemophilus influenzae.

scientific article published on September 2014

Stepwise evolution of Salmonella Typhimurium ST313 causing bloodstream infection in Africa

scientific article published on 21 December 2020

Temperature-regulated efflux pump/potassium antiporter system mediates resistance to cationic antimicrobial peptides in Yersinia

scientific article published on July 2000

The biosynthesis and biological role of lipopolysaccharide O-antigens of pathogenic Yersiniae

scientific article published on November 2003

The intrinsic resistome of Klebsiella pneumoniae

scientific article published on 17 September 2018

The lipopolysaccharide core of Brucella abortus acts as a shield against innate immunity recognition

scientific article

The lipopolysaccharide outer core of Yersinia enterocolitica serotype O:3 is required for virulence and plays a role in outer membrane integrity

scientific article published on March 1999

The outer membrane of Brucella ovis shows increased permeability to hydrophobic probes and is more susceptible to cationic peptides than are the outer membranes of mutant rough Brucella abortus strains

scientific article

The pmrF polymyxin-resistance operon of Yersinia pseudotuberculosis is upregulated by the PhoP-PhoQ two-component system but not by PmrA-PmrB, and is not required for virulence.

scientific article published on December 2004

The uptake of a Klebsiella pneumoniae capsule polysaccharide mutant triggers an inflammatory response by human airway epithelial cells

scientific article

Vibrio cholerae amino acids go on the defense

scientific article published in December 2017

Viruses to fight other viruses: the influenza vaccine case

scientific article published on 22 April 2020

[Correlation between TLR2 and TLR4 levels and adrenal gland response in trauma patients]

scientific article published on 19 March 2012

List of works by José Antonio Bengoechea

2-Hydroxylation of Lipid A Contributes to Virulence

A Klebsiella pneumoniae antibiotic resistance mechanism that subdues host defences and promotes virulence

A Porcine Ex Vivo Lung Perfusion Model To Investigate Bacterial Pathogenesis

An unbiased genetic screen reveals the polygenic nature of the influenza virus anti-interferon response.

Analysis of the networks controlling the antimicrobial-peptide-dependent induction of Klebsiella pneumoniae virulence factors

Apoptosis, Toll-like, RIG-I-like and NOD-like Receptors Are Pathways Jointly Induced by Diverse Respiratory Bacterial and Viral Pathogens

Bactericidal activity of Lys49 and Asp49 myotoxic phospholipases A2 from Bothrops asper snake venom--synthetic Lys49 myotoxin II-(115-129)-peptide identifies its bactericidal region

Brucella abortus and its closest phylogenetic relative, Ochrobactrum spp., differ in outer membrane permeability and cationic peptide resistance

Capsule polysaccharide is a bacterial decoy for antimicrobial peptides

Capsule polysaccharide mediates bacterial resistance to antimicrobial peptides

Characterization and biological role of the O-polysaccharide gene cluster of Yersinia enterocolitica serotype O:9

Characterization of nontypable Haemophilus influenzae isolates recovered from adult patients with underlying chronic lung disease reveals genotypic and phenotypic traits associated with persistent infection.

Characterization of the six glycosyltransferases involved in the biosynthesis of Yersinia enterocolitica serotype O:3 lipopolysaccharide outer core

Chronic obstructive pulmonary disease Th1 cells display impaired response to endotoxin

Clearance of intracellular Klebsiella pneumoniae infection using gentamicin-loaded nanoparticles

Comparative analysis of Klebsiella pneumoniae genomes identifies a phospholipase D family protein as a novel virulence factor

Complement factor H is a serum-binding protein for adrenomedullin, and the resulting complex modulates the bioactivities of both partners

Control of Klebsiella pneumoniae Infection in Mice by Using Dissolving Microarray Patches Containing Gentamicin

Correction: Elucidation of the RamA Regulon in Klebsiella pneumoniae Reveals a Role in LPS Regulation

Deciphering the acylation pattern of Yersinia enterocolitica lipid A.

Deciphering tissue-induced Klebsiella pneumoniae lipid A structure.

Defective B cell response to TLR9 ligand (CpG-ODN), Streptococcus pneumoniae and Haemophilus influenzae extracts in common variable immunodeficiency patients

Dissection of host cell signal transduction during Acinetobacter baumannii-triggered inflammatory response

Efficacy of cecropin A-melittin peptides on a sepsis model of infection by pan-resistant Acinetobacter baumannii

Electronic cigarette vapour increases virulence and inflammatory potential of respiratory pathogens

Elucidation of the RamA regulon in Klebsiella pneumoniae reveals a role in LPS regulation

Evidence for a non-replicative intracellular stage of nontypable Haemophilus influenzae in epithelial cells.

Evolution of colistin resistance in the Klebsiella pneumoniae complex follows multiple evolutionary trajectories with variable effects on fitness and virulence characteristics

Experimental pig yersiniosis to assess attenuation of Yersinia enterocolitica O:8 mutant strains.

Expression of Toll-like receptor 2 is up-regulated in monocytes from patients with chronic obstructive pulmonary disease

Expression of the Yersinia enterocolitica pYV-encoded type III secretion system is modulated by lipopolysaccharide O-antigen status

Expression of toll-like receptors 2 and 4 is upregulated during hospital admission in traumatic patients: lack of correlation with blunted innate immune responses

Functional Genomic Screen Identifies Klebsiella pneumoniae Factors Implicated in Blocking Nuclear Factor κB (NF-κB) Signaling

Functional characterization of Gne (UDP-N-acetylglucosamine-4-epimerase), Wzz (chain length determinant), and Wzy (O-antigen polymerase) of Yersinia enterocolitica serotype O:8

Functional genomics to identify therapeutic prophylactic targets.

Generation of replication-proficient influenza virus NS1 point mutants with interferon-hyperinducer phenotype.

Genome Expression Profiling-Based Identification and Administration Efficacy of Host-Directed Antimicrobial Drugs against Respiratory Infection by Nontypeable Haemophilus influenzae.

Genotypic and phenotypic diversity of the noncapsulated Haemophilus influenzae: adaptation and pathogenesis in the human airways.

Glutamine as a modulator of the immune system of critical care patients: effect on Toll-like receptor expression. A preliminary study

Host cell kinases, α5 and β1 integrins, and Rac1 signalling on the microtubule cytoskeleton are important for non-typable Haemophilus influenzae invasion of respiratory epithelial cells

Identification and Characterization of Two Klebsiella pneumoniae lpxL Lipid A Late Acyltransferases and Their Role in Virulence

Identification of lptA, lpxE, and lpxO, Three Genes Involved in the Remodeling of Brucella Cell Envelope.

Identification of the lipopolysaccharide core of Yersinia pestis and Yersinia pseudotuberculosis as the receptor for bacteriophage φA1122.

Impact of cigarette smoke exposure on host-bacterial pathogen interactions.

Infection systems biology: from reactive to proactive (P4) medicine

Investigating intracellular persistence of Staphylococcus aureus within a murine alveolar macrophage cell line.

Klebsiella pneumoniae AcrAB efflux pump contributes to antimicrobial resistance and virulence

Klebsiella pneumoniae Capsule Polysaccharide Impedes the Expression of ?-Defensins by Airway Epithelial Cells.

Klebsiella pneumoniae OmpA confers resistance to antimicrobial peptides

Klebsiella pneumoniae Reduces SUMOylation To Limit Host Defense Responses

Klebsiella pneumoniae capsule polysaccharide impedes the expression of beta-defensins by airway epithelial cells

Klebsiella pneumoniae increases the levels of Toll-like receptors 2 and 4 in human airway epithelial cells

Klebsiella pneumoniae infection biology: living to counteract host defences

Klebsiella pneumoniae outer membrane protein A is required to prevent the activation of airway epithelial cells.

Klebsiella pneumoniae subverts the activation of inflammatory responses in a NOD1-dependent manner.

Klebsiella pneumoniae survives within macrophages by avoiding delivery to lysosomes

Klebsiella pneumoniae targets an EGF receptor-dependent pathway to subvert inflammation.

Klebsiella pneumoniae triggers a cytotoxic effect on airway epithelial cells

Klebsiella pneumoniae type VI secretion system-mediated microbial competition is PhoPQ controlled and reactive oxygen species dependent

Klebsiella sweet deadly kiss.

Lack of effect of glutamine administration to boost the innate immune system response in trauma patients in the intensive care unit

Lipopolysaccharide O antigen status of Yersinia enterocolitica O:8 is essential for virulence and absence of O antigen affects the expression of other Yersinia virulence factors

Lipopolysaccharide-binding protein and CD14 are increased in the bronchoalveolar lavage fluid of smokers

Modeling Klebsiella pneumoniae pathogenesis by infection of the wax moth Galleria mellonella.

Modulation of Haemophilus influenzae interaction with hydrophobic molecules by the VacJ/MlaA lipoprotein impacts strongly on its interplay with the airways.

Molecular basis of Yersinia enterocolitica temperature-dependent resistance to antimicrobial peptides.

Molecular evolution of proadrenomedullin N-terminal 20 peptide (PAMP): evidence for gene co-option

Nanodelivery strategies for the treatment of multidrug-resistant bacterial infections

Natural killer cell-intrinsic type I IFN signaling controls Klebsiella pneumoniae growth during lung infection.

Nontypable Haemophilus influenzae displays a prevalent surface structure molecular pattern in clinical isolates.

Nontypeable Haemophilus influenzae clearance by alveolar macrophages is impaired by exposure to cigarette smoke

Outer membrane differences between pathogenic and environmental Yersinia enterocolitica biogroups probed with hydrophobic permeants and polycationic peptides

PYHIN1 regulates pro-inflammatory cytokine induction rather than innate immune DNA sensing in airway epithelial cells

Pathogenic Yersinia enterocolitica strains increase the outer membrane permeability in response to environmental stimuli by modulating lipopolysaccharide fluidity and lipid A structure

Phosphoethanolamine modification of lipid A in colistin-resistant variants of Acinetobacter baumannii mediated by the pmrAB two-component regulatory system.

Proper expression of the O-antigen of lipopolysaccharide is essential for the virulence of Yersinia enterocolitica O:8 in experimental oral infection of rabbits

Quinolones sensitize gram-negative bacteria to antimicrobial peptides

Regulatory network of lipopolysaccharide O-antigen biosynthesis in Yersinia enterocolitica includes cell envelope-dependent signals

Relationship between azithromycin susceptibility and administration efficacy for nontypeable Haemophilus influenzae respiratory infection