List of works - Caroline Genco

A novel fur- and iron-regulated small RNA, NrrF, is required for indirect fur-mediated regulation of the sdhA and sdhC genes in Neisseria meningitidis

scientific article

Animal models for Porphyromonas gingivalis-mediated periodontal disease.

scientific article

Antimicrobial activity of magainin analogues against anaerobic oral pathogens.

scientific article published in January 2003

Antiviral effects of synthetic membrane-active peptides on herpes simplex virus, type 1.

scientific article published in September 1999

Binding specificity of the Porphyromonas gingivalis heme and hemoglobin receptor HmuR, gingipain K, and gingipain R1 for heme, porphyrins, and metalloporphyrins

scientific article

Biomolecular detection employing the Interferometric Reflectance Imaging Sensor (IRIS).

scientific article

Characterization and expression of HmuR, a TonB-dependent hemoglobin receptor of Porphyromonas gingivalis

scientific article

Characterization of a novel Neisseria meningitidis Fur and iron-regulated operon required for protection from oxidative stress: utility of DNA microarray in the assignment of the biological role of hypothetical genes.

scientific article

Conjugation of Plasmids of Neisseria gonorrhoeae to other Neisseria Species: Potential Reservoirs for the -Lactamase Plasmid

scientific article published on 01 September 1984

Coordinate expression of the Porphyromonas gingivalis lysine-specific gingipain proteinase, Kgp, arginine-specific gingipain proteinase, RgpA, and the heme/hemoglobin receptor, HmuR.

scientific article published in November 2004

Degradation of host heme proteins by lysine- and arginine-specific cysteine proteinases (gingipains) of Porphyromonas gingivalis.

scientific article

Directing TRAF-ic: cell-specific TRAF6 signaling in chronic inflammation and atherosclerosis

scientific article published in October 2012

Disruption of immune regulation by microbial pathogens and resulting chronic inflammation.

scientific article published on July 2013

Emerging strategies in microbial haem capture.

scientific article

Enhanced neutrophil emigration and Porphyromonas gingivalis reduction following PGG-glucan treatment of mice.

scientific article published in August 2002

Environmental cues and gene expression in Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans.

scientific article

Expression of the iron-activated nspA and secY genes in Neisseria meningitidis group B by Fur-dependent and -independent mechanisms

scientific article

Fur-mediated global regulatory circuits in pathogenic Neisseria species.

scientific article

Genetic diversity of the iron-binding protein (Fbp) gene of the pathogenic and commensalNeisseria

article

Gingipain-specific IgG in the sera of patients with periodontal disease is necessary for opsonophagocytosis of Porphyromonas gingivalis

scientific article

Hemin-dependent modulation of the lipid A structure of Porphyromonas gingivalis lipopolysaccharide

scientific article

Identification of amino acid residues involved in heme binding and hemoprotein utilization in the Porphyromonas gingivalis heme receptor HmuR.

scientific article

Identification of iron-activated and -repressed Fur-dependent genes by transcriptome analysis of Neisseria meningitidis group B.

scientific article

Inducible nitric oxide synthase mediates bone development and P. gingivalis-induced alveolar bone loss

scientific article published on 01 March 2005

Innate immune recognition of invasive bacteria accelerates atherosclerosis in apolipoprotein E-deficient mice

scientific article

Innate immune signaling and Porphyromonas gingivalis-accelerated atherosclerosis.

scientific article

Iron and heme utilization in Porphyromonas gingivalis.

scientific article

Lysine-specific gingipain K and heme/hemoglobin receptor HmuR are involved in heme utilization in Porphyromonas gingivalis.

scientific article published in January 2004

Macrophage-elicited osteoclastogenesis in response to bacterial stimulation requires Toll-like receptor 2-dependent tumor necrosis factor-alpha production.

scientific article published on 12 November 2007

Macrophage-specific TLR2 signaling mediates pathogen-induced TNF-dependent inflammatory oral bone loss

scientific article published on 21 December 2012

Microbial carriage state of peripheral blood dendritic cells (DCs) in chronic periodontitis influences DC differentiation, atherogenic potential.

scientific article

Microbial lipid A remodeling controls cross-presentation efficiency and CD8 T cell priming by modulating dendritic cell function

scientific article published on 30 November 2020

Molecular cloning and characterization of the structural gene for the major iron-regulated protein expressed by Neisseria gonorrhoeae.

scientific article

Noncanonical dendritic cell differentiation and survival driven by a bacteremic pathogen.

scientific article published on 31 May 2013

Pathogen-accelerated atherosclerosis occurs early after exposure and can be prevented via immunization.

scientific article

Pathogen-mediated inflammatory atherosclerosis is mediated in part via Toll-like receptor 2-induced inflammatory responses.

scientific article published on 10 May 2010

Pathogen-mediated proteolysis of the cell death regulator RIPK1 and the host defense modulator RIPK2 in human aortic endothelial cells.

scientific article

Pathogenic neisseriae can use hemoglobin, transferrin, and lactoferrin independently of the tonB locus.

scientific article

Porphyromonas gingivalis fimbria-dependent activation of inflammatory genes in human aortic endothelial cells.

scientific article

Porphyromonas gingivalis mediated periodontal disease and atherosclerosis: disparate diseases with commonalities in pathogenesis through TLRs.

scientific article published on January 2007

Porphyromonas gingivalis-specific immunoglobulin G prevents P. gingivalis-elicited oral bone loss in a murine model.

scientific article published on April 2004

Preface: Molecular and Cellular Basis for Microbial Pathogenesis

scientific article published on 01 February 1995

Prevention of Porphyromonas gingivalis-induced oral bone loss following immunization with gingipain R1.

scientific article

Protective role for TLR4 signaling in atherosclerosis progression as revealed by infection with a common oral pathogen

scientific article

Regulation of hemin and iron transport in Porphyromonas gingivalis.

scientific article published on February 1995

Review: Pathogen-induced inflammation at sites distant from oral infection: bacterial persistence and induction of cell-specific innate immune inflammatory pathways.

scientific article

Role for fimbriae and lysine-specific cysteine proteinase gingipain K in expression of interleukin-8 and monocyte chemoattractant protein in Porphyromonas gingivalis-infected endothelial cells.

scientific article

Role of FNR and FNR-regulated, sugar fermentation genes in Neisseria meningitidis infection

scientific article

Role of Hfq in iron-dependent and -independent gene regulation in Neisseria meningitidis.

scientific article published on 29 April 2010

Roles of the host oxidative immune response and bacterial antioxidant rubrerythrin during Porphyromonas gingivalis infection.

scientific article

Stimulation of Toll-like receptor 2 in human platelets induces a thromboinflammatory response through activation of phosphoinositide 3-kinase

scientific article published on 23 December 2008

Susceptibility trends of zoliflodacin against multidrug-resistant <i>Neisseria gonorrhoeae</i> clinical isolates in Nanjing, China (2014-2018)

scientific article published on 14 December 2020

The C-terminal domains of the gingipain K polyprotein are necessary for assembly of the active enzyme and expression of associated activities

scientific article published in December 2004

The gonococcal fur regulon: identification of additional genes involved in major catabolic, recombination, and secretory pathways.

scientific article

Toll-like receptor 2 plays a critical role in the progression of atherosclerosis that is independent of dietary lipids.

scientific article

Virulence factors of Porphyromonas gingivalis.

scientific article

cis- and trans-acting elements involved in regulation of norB (norZ), the gene encoding nitric oxide reductase in Neisseria gonorrhoeae.

scientific article published in January 2008

List of works by Caroline Genco

A novel fur- and iron-regulated small RNA, NrrF, is required for indirect fur-mediated regulation of the sdhA and sdhC genes in Neisseria meningitidis

Animal models for Porphyromonas gingivalis-mediated periodontal disease.

Antimicrobial activity of magainin analogues against anaerobic oral pathogens.

Antiviral effects of synthetic membrane-active peptides on herpes simplex virus, type 1.

Binding specificity of the Porphyromonas gingivalis heme and hemoglobin receptor HmuR, gingipain K, and gingipain R1 for heme, porphyrins, and metalloporphyrins

Biomolecular detection employing the Interferometric Reflectance Imaging Sensor (IRIS).

Characterization and expression of HmuR, a TonB-dependent hemoglobin receptor of Porphyromonas gingivalis

Characterization of a novel Neisseria meningitidis Fur and iron-regulated operon required for protection from oxidative stress: utility of DNA microarray in the assignment of the biological role of hypothetical genes.

Conjugation of Plasmids of Neisseria gonorrhoeae to other Neisseria Species: Potential Reservoirs for the -Lactamase Plasmid

Coordinate expression of the Porphyromonas gingivalis lysine-specific gingipain proteinase, Kgp, arginine-specific gingipain proteinase, RgpA, and the heme/hemoglobin receptor, HmuR.

Degradation of host heme proteins by lysine- and arginine-specific cysteine proteinases (gingipains) of Porphyromonas gingivalis.

Directing TRAF-ic: cell-specific TRAF6 signaling in chronic inflammation and atherosclerosis

Disruption of immune regulation by microbial pathogens and resulting chronic inflammation.

Emerging strategies in microbial haem capture.

Enhanced neutrophil emigration and Porphyromonas gingivalis reduction following PGG-glucan treatment of mice.

Environmental cues and gene expression in Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans.

Expression of the iron-activated nspA and secY genes in Neisseria meningitidis group B by Fur-dependent and -independent mechanisms

Fur-mediated global regulatory circuits in pathogenic Neisseria species.

Genetic diversity of the iron-binding protein (Fbp) gene of the pathogenic and commensalNeisseria

Gingipain-specific IgG in the sera of patients with periodontal disease is necessary for opsonophagocytosis of Porphyromonas gingivalis

Hemin-dependent modulation of the lipid A structure of Porphyromonas gingivalis lipopolysaccharide

Identification of amino acid residues involved in heme binding and hemoprotein utilization in the Porphyromonas gingivalis heme receptor HmuR.

Identification of iron-activated and -repressed Fur-dependent genes by transcriptome analysis of Neisseria meningitidis group B.

Inducible nitric oxide synthase mediates bone development and P. gingivalis-induced alveolar bone loss

Innate immune recognition of invasive bacteria accelerates atherosclerosis in apolipoprotein E-deficient mice

Innate immune signaling and Porphyromonas gingivalis-accelerated atherosclerosis.

Iron and heme utilization in Porphyromonas gingivalis.

Lysine-specific gingipain K and heme/hemoglobin receptor HmuR are involved in heme utilization in Porphyromonas gingivalis.

Macrophage-elicited osteoclastogenesis in response to bacterial stimulation requires Toll-like receptor 2-dependent tumor necrosis factor-alpha production.

Macrophage-specific TLR2 signaling mediates pathogen-induced TNF-dependent inflammatory oral bone loss

Microbial carriage state of peripheral blood dendritic cells (DCs) in chronic periodontitis influences DC differentiation, atherogenic potential.

Microbial lipid A remodeling controls cross-presentation efficiency and CD8 T cell priming by modulating dendritic cell function

Molecular cloning and characterization of the structural gene for the major iron-regulated protein expressed by Neisseria gonorrhoeae.

Noncanonical dendritic cell differentiation and survival driven by a bacteremic pathogen.

Pathogen-accelerated atherosclerosis occurs early after exposure and can be prevented via immunization.

Pathogen-mediated inflammatory atherosclerosis is mediated in part via Toll-like receptor 2-induced inflammatory responses.

Pathogen-mediated proteolysis of the cell death regulator RIPK1 and the host defense modulator RIPK2 in human aortic endothelial cells.

Pathogenic neisseriae can use hemoglobin, transferrin, and lactoferrin independently of the tonB locus.

Porphyromonas gingivalis fimbria-dependent activation of inflammatory genes in human aortic endothelial cells.

Porphyromonas gingivalis mediated periodontal disease and atherosclerosis: disparate diseases with commonalities in pathogenesis through TLRs.

Porphyromonas gingivalis-specific immunoglobulin G prevents P. gingivalis-elicited oral bone loss in a murine model.

Preface: Molecular and Cellular Basis for Microbial Pathogenesis

Prevention of Porphyromonas gingivalis-induced oral bone loss following immunization with gingipain R1.

Protective role for TLR4 signaling in atherosclerosis progression as revealed by infection with a common oral pathogen

Regulation of hemin and iron transport in Porphyromonas gingivalis.

Review: Pathogen-induced inflammation at sites distant from oral infection: bacterial persistence and induction of cell-specific innate immune inflammatory pathways.

Role for fimbriae and lysine-specific cysteine proteinase gingipain K in expression of interleukin-8 and monocyte chemoattractant protein in Porphyromonas gingivalis-infected endothelial cells.

Role of FNR and FNR-regulated, sugar fermentation genes in Neisseria meningitidis infection

Role of Hfq in iron-dependent and -independent gene regulation in Neisseria meningitidis.

Roles of the host oxidative immune response and bacterial antioxidant rubrerythrin during Porphyromonas gingivalis infection.

Stimulation of Toll-like receptor 2 in human platelets induces a thromboinflammatory response through activation of phosphoinositide 3-kinase

Susceptibility trends of zoliflodacin against multidrug-resistant <i>Neisseria gonorrhoeae</i> clinical isolates in Nanjing, China (2014-2018)

The C-terminal domains of the gingipain K polyprotein are necessary for assembly of the active enzyme and expression of associated activities

The gonococcal fur regulon: identification of additional genes involved in major catabolic, recombination, and secretory pathways.

Toll-like receptor 2 plays a critical role in the progression of atherosclerosis that is independent of dietary lipids.

Virulence factors of Porphyromonas gingivalis.

cis- and trans-acting elements involved in regulation of norB (norZ), the gene encoding nitric oxide reductase in Neisseria gonorrhoeae.