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List of works by Paul J Farrell

A new and sensitive method of screening for human papillomavirus infection

scientific article published on September 1989

A novel deletion within the upstream regulatory region of episomal human papillomavirus type 16.

scientific article

A promoter for the highly spliced EBNA family of RNAs of Epstein-Barr virus.

scientific article published on November 1987

A simple technique to enhance the humoral immune response to intracellular protein antigens in genetic immunizations.

scientific article published on 3 September 2012

A single amino acid in EBNA-2 determines superior B lymphoblastoid cell line growth maintenance by Epstein-Barr virus type 1 EBNA-2.

scientific article

A strategy for specific targeting of therapeutic agents to tumour cells of virus-associated cancers

scientific article published in March 1997

Accumulation of an mRNA and protein in interferon-treated Ehrlich ascites tumour cells

scientific article published in June 1979

Activators of the Epstein-Barr virus lytic program concomitantly induce apoptosis, but lytic gene expression protects from cell death

scientific article published on March 2001

Analysis of Phosphorylation of Protein Synthesis Initiation Factor eIF-2 by Two-Dimensional Gel Electrophoresis

scientific article published on 01 September 1978

Application of a generalized random effects regression model for cluster-correlated longitudinal data to a school-based smoking prevention trial.

scientific article

Are particular Epstein-Barr virus strains linked to disease?

scientific article

Association of innate immune activation with latent Epstein-Barr virus in active MS lesions.

scientific article published on 7 December 2011

Biological activities of p53 mutants in Burkitt's lymphoma cells

scientific article published on May 1993

C-terminal region of EBNA-2 determines the superior transforming ability of type 1 Epstein-Barr virus by enhanced gene regulation of LMP-1 and CXCR7.

scientific article

Can plasma Epstein-Barr virus DNA levels be used to monitor nasopharyngeal carcinoma progression?

scientific article

Cell cycle arrest following exposure of EBV-immortalised B-cells to gamma irradiation correlates with inhibition of cdk2 activity

scientific article published on November 1998

Cell growth effects of Epstein-Barr virus leader protein.

scientific article

Cell target genes of Epstein-Barr virus transcription factor EBNA-2: induction of the p55alpha regulatory subunit of PI3-kinase and its role in survival of EREB2.5 cells

scientific article published on October 2006

Cell-switching and kissing

scientific article published on 01 June 2002

Cellular gene expression that correlates with EBER expression in Epstein-Barr Virus-infected lymphoblastoid cell lines

scientific article published on 19 January 2011

Chromatin structure of Epstein-Barr virus

scientific article

Coding content and expression of the EBV B95-8 genome in the region from base 62,248 to base 82,920

scientific article published on 01 July 1986

Coincident inactivation of 14-3-3sigma and p16INK4a is an early event in vulval squamous neoplasia

scientific article published in March 2002

Concomitant inactivation of p53 and Chk2 in breast cancer

Control of cell cycle entry and apoptosis in B lymphocytes infected by Epstein-Barr virus.

scientific article

Cryptogenic fibrosing alveolitis: lack of association with Epstein-Barr virus infection

scientific article published in October 1997

DNA damage in human B cells can induce apoptosis, proceeding from G1/S when p53 is transactivation competent and G2/M when it is transactivation defective.

scientific article

DNA sequence analysis of the EcoRI Dhet fragment of B95-8 Epstein-Barr virus containing the terminal repeat sequences

scientific article published in November 1983

DNA sequence and expression of the B95-8 Epstein-Barr virus genome.

scientific article

DNA sequence and transcription of the BamHI fragment B region of B95-8 Epstein-Barr virus

scientific article published in October 1983

Differences in B cell growth phenotype reflect novel patterns of Epstein-Barr virus latent gene expression in Burkitt's lymphoma cells

scientific article

Differential gene regulation by Epstein-Barr virus type 1 and type 2 EBNA2.

scientific article

Differential splicing of Epstein-Barr virus immediate-early RNA.

scientific article published on October 1992

Direct and indirect regulation of cytokine and cell cycle proteins by EBNA-2 during Epstein-Barr virus infection

scientific article

Direct demonstration of persistent Epstein-Barr virus gene expression in peripheral blood of infected common marmosets and analysis of virus-infected tissues in vivo

scientific article published in June 1997

Downregulation of RUNX1 by RUNX3 requires the RUNX3 VWRPY sequence and is essential for Epstein-Barr virus-driven B-cell proliferation

scientific article published on 29 April 2009

E7 proteins from oncogenic human papillomavirus types transactivate p73: role in cervical intraepithelial neoplasia

scientific article published on January 2002

EBNA-2 and EBNA-LP cooperate to cause G0 to G1 transition during immortalization of resting human B lymphocytes by Epstein-Barr virus.

scientific article

EBNA2 driven enhancer switching at the CIITA-DEXI locus suppresses HLA class II gene expression during EBV infection of B-lymphocytes ⬇️

scientific article published on 05 August 2021

Effect of endogenous proteins on growth and antibody productivity in hybridoma batch cultures

scientific article published on January 1994

Epigenetic inactivation of 14-3-3 sigma in oral carcinoma: association with p16(INK4a) silencing and human papillomavirus negativity

scientific article published on 01 April 2002

Epstein-Barr virus BART gene expression.

scientific article

Epstein-Barr virus BZLF1 trans-activator specifically binds to a consensus AP-1 site and is related to c-fos

scientific article published on January 1989

Epstein-Barr virus EBNA-LP and transcription regulation properties of pRB, p107 and p53 in transfection assays.

scientific article

Epstein-Barr virus EBNA3C represses Cp, the major promoter for EBNA expression, but has no effect on the promoter of the cell gene CD21.

scientific article

Epstein-Barr virus SM protein

scientific article published on November 1994

Epstein-Barr virus and Burkitt lymphoma

scientific article

Epstein-Barr virus efficiently immortalizes human B cells without neutralizing the function of p53

scientific article published on April 1995

Epstein-Barr virus exploits the normal cell pathway to regulate Rb activity during the immortalisation of primary B-cells

scientific article published on October 1996

Epstein-Barr virus gene expression in oral hairy leukoplakia.

scientific article published on August 1993

Epstein-Barr virus genes and cancer cells

scientific article published on January 1997

Epstein-Barr virus immortalizing genes

scientific article published on March 1995

Epstein-Barr virus nuclear antigen (EBNA)3C is an immortalizing oncoprotein with similar properties to adenovirus E1A and papillomavirus E7.

scientific article published in December 1996

Epstein-Barr virus nuclear antigen 3C is a powerful repressor of transcription when tethered to DNA.

scientific article published on April 1996

Epstein-Barr virus nuclear antigen EBNA3C/6 expression maintains the level of latent membrane protein 1 in G1-arrested cells

scientific article published on June 1994

Epstein-Barr virus origin of lytic replication mediates association of replicating episomes with promyelocytic leukaemia protein nuclear bodies and replication compartments

scientific article published on May 2006

Epstein-Barr virus transcription factors

scientific article

Essential role of inverted repeat in Epstein-Barr virus IR-1 in B cell transformation; geographical variation of the viral genome

scientific article published on 01 May 2019

Expression of cyclin D2 in Epstein-Barr virus-positive Burkitt's lymphoma cell lines is related to methylation status of the gene

scientific article published on February 1995

Expression of transcription factor AML-2 (RUNX3, CBF(alpha)-3) is induced by Epstein-Barr virus EBNA-2 and correlates with the B-cell activation phenotype

scientific article

Extracts of interferon-treated cells can inhibit reticulocyte lysate protein synthesis

scientific article published on July 1977

Genomic organization and functional expression of differentially regulated cysteine protease genes of Leishmania donovani complex

scientific article published in January 2002

Genomic sequencing and comparative analysis of Epstein-Barr virus genome isolated from primary nasopharyngeal carcinoma biopsy.

scientific article

High rate of human papillomavirus type 16 infection in cytologically normal cervices

retracted scientific article published in The Lancet

Histone acetylation and reactivation of Epstein-Barr virus from latency.

scientific article

Homologous upstream sequences near Epstein-Barr virus promoters.

scientific article published on March 1983

Host cell and EBNA-2 regulation of Epstein-Barr virus latent-cycle promoter activity in B lymphocytes.

scientific article published on January 1992

Host cell requirements for efficient infection of quiescent primary B lymphocytes by Epstein-Barr virus.

scientific article published on September 1995

Interaction of Epstein-Barr virus BZLF1 C-terminal tail structure and core zipper is required for DNA replication but not for promoter transactivation

scientific article

Interferon action: two distinct pathways for inhibition of protein synthesis by double-stranded RNA ⬇️

scientific article published on December 1, 1978

Interferon, double-stranded RNA and RNA degradation. Fractionation of the endonucleaseINT system into two macromolecular components; role of a small molecule in nuclease activation

scientific article published on 01 April 1978

Interferon, double-stranded RNA, and RNA degradation. Isolation of homogeneous pppA(2'p5'A)n-1 synthetase from Ehrlich ascites tumor cells

scientific article published on 01 May 1980

Latent and lytic cycle promoters of Epstein-Barr virus

scientific article published on January 1983

Lytic Epstein-Barr virus infection in epithelial cells but not in B-lymphocytes is dependent on Blimp1.

scientific article published on 25 January 2012

Lytic cycle gene regulation of Epstein-Barr virus

scientific article

Molecular genetic analysis of Epstein-Barr virus Cp promoter function

scientific article published in March 1996

Molluscum Contagiosum Virus Protein MC005 Inhibits NF-κB Activation by Targeting NEMO-Regulated IκB Kinase Activation.

scientific article

Multiple functions within the Epstein-Barr virus EBNA-3A protein.

scientific article published on March 1998

Natural Variation of Epstein-Barr Virus Genes, Proteins, and Primary MicroRNA.

scientific article

Novel function of the unique N-terminal region of RUNX1c in B cell growth regulation

scientific article published on 18 December 2012

Novel hypotheses for the roles of EBNA-1 and BHRF1 in EBV-related cancers

scientific article published on 01 January 1995

Novel nuclear antigens recognized by human sera in lymphocytes latently infected by Epstein-Barr virus

scientific article

Pathways of activation of the Epstein-Barr virus productive cycle

scientific article published on May 1991

Phosphorylation of initiation factor elF-2 and the control of reticulocyte protein synthesis

scientific article

Polymerase chain reaction for detection of dissemination in gastric lymphoma

scientific article published in April 1989

Polymorphism in wild-type p53 modulates response to chemotherapy in vitro and in vivo

scientific article published on April 2004

Preferential retention of codon 72 arginine p53 in squamous cell carcinomas of the vulva occurs in cancers positive and negative for human papillomavirus

scientific article published on 01 December 2000

Prevalence of human papillomavirus type 16 DNA in cervical carcinoma samples in East Anglia

scientific article published on February 1985

Promoter sequences required for reactivation of Epstein-Barr virus from latency

scientific article published on October 2002

RUNX expression and function in human B cells.

scientific article

RUNX3-mediated repression of RUNX1 in B cells.

scientific article

Reactivation of Epstein-Barr virus from latency

scientific article (publication date: 2005)

Reciprocal antagonism of steroid hormones and BZLF1 in switch between Epstein-Barr virus latent and productive cycle gene expression

scientific article published on January 1992

Reduced signal transduction through glucocorticoid receptor in Burkitt's lymphoma cell lines

scientific article published on March 1994

Regulation of cell growth and death by Epstein-Barr virus

scientific article

Regulation of the Epstein-Barr virus Zp promoter in B lymphocytes during reactivation from latency

scientific article

Relation between infection with a subtype of HPV16 and cervical neoplasia

retracted scientific article published in The Lancet

Retraction: human papillomavirus subtype 16b

scientific article published on 01 December 1989

Role for HLA in susceptibility to infectious mononucleosis

scientific article published on October 2007

Sequence analysis of Raji Epstein-Barr virus DNA.

scientific article

Sequence analysis of the 17,166 base-pair EcoRI fragment C of B95-8 Epstein-Barr virus.

scientific article published in July 1983

Sequence and transcription of Raji Epstein-Barr virus DNA spanning the B95-8 deletion region

scientific article published on November 1990

Signal Transduction and Transcription Factor Modification during Reactivation of Epstein-Barr Virus from Latency

scientific article

Signal transducer and activator of transcription 3 limits Epstein-Barr virus lytic activation in B lymphocytes.

scientific article published on 21 August 2013

Signal transduction from the Epstein-Barr virus LMP-1 transforming protein

scientific article published in May 1998

Strain variation in Epstein-Barr virus immediate early genes.

scientific article

Structure and coding content of CST (BART) family RNAs of Epstein-Barr virus

scientific article

Structure and function of the Epstein-Barr virus BZLF1 protein

scientific article

The -1195G allele increases the transcriptional activity of cyclooxygenase-2 gene (COX-2) in colon cancer cell lines

scientific article published on 18 June 2013

The BZLF1 protein of EBV has a coiled coil dimerisation domain without a heptad leucine repeat but with homology to the C/EBP leucine zipper

scientific article published on 01 February 1991

The Cooperative Functions of the EBNA3 Proteins Are Central to EBV Persistence and Latency.

scientific article

The collagen prolyl hydroxylases are novel transcriptionally silenced genes in lymphoma

scientific article published on 6 September 2012

The expression of variant CD44 in nasopharyngeal carcinoma is unrelated to expression of LMP-1

scientific article published on May 1995

The role of Epstein-Barr virus in cancer

scientific article

The spliced BZLF1 gene of Epstein-Barr virus (EBV) transactivates an early EBV promoter and induces the virus productive cycle.

scientific article published on July 1989

The terminal protein gene 2 of Epstein-Barr virus is transcribed from a bidirectional latent promoter region

scientific article published in November 1989

Towards a multi-level and a multi-disciplinary approach to DNA oncovirus virulence

scientific article published on 01 May 2019

Transcription and DNA sequence of the BamHI L fragment of B95-8 Epstein-Barr virus.

scientific article published on May 1984

Transcriptional cross-regulation of RUNX1 by RUNX3 in human B cells.

scientific article

Transcriptional silencing of Polo-like kinase 2 (SNK/PLK2) is a frequent event in B-cell malignancies.

scientific article published on 13 September 2005

Tumour viruses--could they be an Achilles' heel of cancer?

scientific article published on 01 September 2002

Two related but differentially expressed potential membrane proteins encoded by the EcoRI Dhet region of Epstein-Barr virus B95-8.

scientific article published on February 1985

Updated Epstein-Barr virus (EBV) DNA sequence and analysis of a promoter for the BART (CST, BARF0) RNAs of EBV.

scientific article published on June 2003

Variant chromatin structure of the oriP region of Epstein-Barr virus and regulation of EBER1 expression by upstream sequences and oriP.

scientific article published on July 2001

Viruses and human cancer

scientific article published on 01 July 1994

X-box binding protein 1 induces the expression of the lytic cycle transactivator of Kaposi's sarcoma-associated herpesvirus but not Epstein-Barr virus in co-infected primary effusion lymphoma

scientific article published on 27 October 2010

p53 is frequently mutated in Burkitt's lymphoma cell lines

scientific article published on October 1991

p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis

scientific article published in April 2003

p73 is over-expressed in vulval cancer principally as the Delta 2 isoform

scientific article

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