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List of works by Nicolas Rapin

An atlas of active enhancers across human cell types and tissues

scientific article

Bistability in autoimmune diseases ⬇️

scientific article published on January 19, 2011

BloodSpot: a database of gene expression profiles and transcriptional programs for healthy and malignant haematopoiesis

scientific article published on 26 October 2015

BloodSpot: a database of healthy and malignant haematopoiesis updated with purified and single cell mRNA sequencing profiles

scientific article published on 01 January 2019

C/EBPα is required for long-term self-renewal and lineage priming of hematopoietic stem cells and for the maintenance of epigenetic configurations in multipotent progenitors

scientific article published on 9 January 2014

CTLs' repertoire shaping in the thymus: a Monte Carlo simulation

scientific article published on 19 January 2011

Cellular origin of prognostic chromosomal aberrations in AML patients

scientific article published on 11 February 2015

Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies.

scientific article published on 25 April 2018

Comparing cancer vs normal gene expression profiles identifies new disease entities and common transcriptional programs in AML patients.

scientific article

Computational immunology meets bioinformatics: the use of prediction tools for molecular binding in the simulation of the immune system

scientific article

ERG promotes the maintenance of hematopoietic stem cells by restricting their differentiation

scientific article published on September 2015

EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas

scientific article published on 27 February 2017

Gaboxadol has affinity for the proton-coupled amino acid transporter 1, SLC36A1 (hPAT1)--A modelling approach to determine IC(50) values of the three ionic species of gaboxadol

scientific article published on 26 November 2010

Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types

scientific article published on 26 January 2017

HemaExplorer: a Web server for easy and fast visualization of gene expression in normal and malignant hematopoiesis

article

HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis

scientific article published on 9 November 2012

Human adult HSCs can be discriminated from lineage-committed HPCs by the expression of endomucin

scientific article published on 01 July 2018

Immune system simulation online

scientific article published on 17 June 2011

ImmunoGrid, an integrative environment for large-scale simulation of the immune system for vaccine discovery, design and optimization

scientific article published on May 2009

ImmunoGrid: towards agent-based simulations of the human immune system at a natural scale

scientific article published on June 2010

Initiation of MLL-rearranged AML is dependent on C/EBPα

scientific article published on 23 December 2013

Intestinal transporters for endogenic and pharmaceutical organic anions: the challenges of deriving in-vitro kinetic parameters for the prediction of clinically relevant drug–drug interactions ⬇️

scientific article published on March 30, 2012

Lack of the p42 form of C/EBPα leads to spontaneous immortalization and lineage infidelity of committed myeloid progenitors

scientific article published on 2 July 2013

Leukemogenic nucleophosmin mutation disrupts the transcription factor hub that regulates granulomonocytic fates

scientific article published on 17 July 2018

Loss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis

scientific article published on 17 April 2015

MHC motif viewer

scientific article published on 3 September 2008

MicroRNA-941 Expression in Polymorphonuclear Granulocytes Is Not Related to Granulomatosis with Polyangiitis

scientific article

Modelling the human immune system by combining bioinformatics and systems biology approaches

scientific article published on 27 October 2006

Oncogenic fusion proteins expressed in immature hematopoietic cells fail to recapitulate the transcriptional changes observed in human AML.

scientific article published on 16 June 2014

Peak-valley-peak pattern of histone modifications delineates active regulatory elements and their directionality

scientific article published on 19 April 2016

SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization

scientific article published on 22 December 2016

Simulating kinetic parameters in transporter mediated permeability across Caco-2 cells. A case study of estrone-3-sulfate ⬇️

scientific article published on August 24, 2011

TGIF1 is a negative regulator of MLL-rearranged acute myeloid leukemia

scientific article

Temporal mapping of CEBPA and CEBPB binding during liver regeneration reveals dynamic occupancy and specific regulatory codes for homeostatic and cell cycle gene batteries

scientific article published on 12 February 2013

The MHC motif viewer: a visualization tool for MHC binding motifs

scientific article

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