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List of works by Albert Giralt

7,8-dihydroxyflavone ameliorates cognitive and motor deficits in a Huntington's disease mouse model through specific activation of the PLCγ1 pathway

scientific article published on 24 May 2017

A role for Kalirin-7 in corticostriatal synaptic dysfunction in Huntington's disease

scientific article

Activation of Elk-1 participates as a neuroprotective compensatory mechanism in models of Huntington's disease

scientific article

Acute drug-induced spine changes in the nucleus accumbens are dependent on β-adducin.

scientific article published on 29 July 2016

Age-dependent decline of motor neocortex but not hippocampal performance in heterozygous BDNF mice correlates with a decrease of cortical PSD-95 but an increase of hippocampal TrkB levels.

scientific article published on 6 July 2012

Age-dependent maintenance of motor control and corticostriatal innervation by death receptor 3.

scientific article

Age-related changes in STriatal-Enriched protein tyrosine Phosphatase levels: Regulation by BDNF.

scientific article published on 6 November 2017

Astrocytic BDNF and TrkB regulate severity and neuronal activity in mouse models of temporal lobe epilepsy

scientific article published on 01 June 2020

BDNF regulation under GFAP promoter provides engineered astrocytes as a new approach for long-term protection in Huntington's disease.

scientific article published on 13 May 2010

Brain-derived neurotrophic factor modulates the severity of cognitive alterations induced by mutant huntingtin: involvement of phospholipaseCgamma activity and glutamate receptor expression

scientific article

Caveolin-1 deficiency causes cholesterol-dependent mitochondrial dysfunction and apoptotic susceptibility.

scientific article published on 14 April 2011

Cognitive Dysfunction in Huntington's Disease: Humans, Mouse Models and Molecular Mechanisms

scientific article

Conditional BDNF Delivery from Astrocytes Rescues Memory Deficits, Spine Density, and Synaptic Properties in the 5xFAD Mouse Model of Alzheimer Disease

scientific article published on 30 January 2019

Conditional BDNF release under pathological conditions improves Huntington's disease pathology by delaying neuronal dysfunction

scientific article

Cryostat Slice Irregularities May Introduce Bias in Tissue Thickness Estimation: Relevance for Cell Counting Methods.

scientific article published on 15 July 2015

Cyclin-Dependent Kinase 5 Dysfunction Contributes to Depressive-like Behaviors in Huntington's Disease by Altering the DARPP-32 Phosphorylation Status in the Nucleus Accumbens

scientific article published on 13 March 2019

Cytotoxic effect of neuromyelitis optica antibody (NMO-IgG) to astrocytes: an in vitro study

scientific article published on 19 August 2009

DARPP-32 interaction with adducin may mediate rapid environmental effects on striatal neurons

scientific article

Differential neuroprotective effects of 5'-deoxy-5'-methylthioadenosine

scientific article

Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease.

scientific article published on 8 March 2012

Disruption of striatal glutamatergic transmission induced by mutant huntingtin involves remodeling of both postsynaptic density and NMDA receptor signaling

scientific article published on 23 October 2007

Dissociation between CA3-CA1 synaptic plasticity and associative learning in TgNTRK3 transgenic mice.

scientific article

Early Downregulation of p75NTR by Genetic and Pharmacological Approaches Delays the Onset of Motor Deficits and Striatal Dysfunction in Huntington's Disease Mice.

scientific article

Early L-dopa, but not pramipexole, restores basal ganglia activity in partially 6-OHDA-lesioned rats

scientific article published on 24 December 2013

Fingolimod (FTY720) enhances hippocampal synaptic plasticity and memory in Huntington's disease by preventing p75NTR up-regulation and astrocyte-mediated inflammation.

scientific article published on 10 June 2015

Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons

scientific article

Helios modulates the maturation of a CA1 neuronal subpopulation required for spatial memory formation

scientific article published on 08 November 2019

Imbalance of p75(NTR)/TrkB protein expression in Huntington's disease: implication for neuroprotective therapies.

scientific article published on 18 April 2013

Increased PKA signaling disrupts recognition memory and spatial memory: role in Huntington's disease

scientific article

Long-term memory deficits in Huntington's disease are associated with reduced CBP histone acetylase activity.

scientific article

Loss of striatal 90-kDa ribosomal S6 kinase (Rsk) is a key factor for motor, synaptic and transcription dysfunction in Huntington's disease

scientific article published on 6 April 2016

Neurobehavioral characterization of Endonuclease G knockout mice reveals a new putative molecular player in the regulation of anxiety

scientific article published on 18 April 2013

Neurotrophin receptor p75(NTR) mediates Huntington's disease-associated synaptic and memory dysfunction

scientific article

PDE10 inhibition increases GluA1 and CREB phosphorylation and improves spatial and recognition memories in a Huntington's disease mouse model

scientific article published on 29 April 2013

PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum.

scientific article

PKR knockout in the 5xFAD model of Alzheimer's disease reveals beneficial effects on spatial memory and brain lesions.

scientific article

PTK2B/Pyk2 overexpression improves a mouse model of Alzheimer's disease.

scientific article

Prostaglandin E2 EP1 receptor antagonist improves motor deficits and rescues memory decline in R6/1 mouse model of Huntington's disease

scientific article published on 7 November 2013

Prostaglandin E2 EP2 activation reduces memory decline in R6/1 mouse model of Huntington's disease by the induction of BDNF-dependent synaptic plasticity.

scientific article published on 11 September 2015

Pyk2 in the amygdala modulates chronic stress sequelae via PSD-95-related micro-structural changes

scientific article published on 15 January 2019

Pyk2 is essential for astrocytes mobility following brain lesion

scientific article published on 11 December 2015

Pyk2 modulates hippocampal excitatory synapses and contributes to cognitive deficits in a Huntington's disease model

scientific article published on 30 May 2017

Reduced calcineurin protein levels and activity in exon-1 mouse models of Huntington's disease: role in excitotoxicity.

scientific article published on 4 September 2009

Regulation of hippocampal cGMP levels as a candidate to treat cognitive deficits in Huntington's disease

scientific article

Striatal-enriched protein tyrosine phosphatase expression and activity in Huntington's disease: a STEP in the resistance to excitotoxicity

scientific article (publication date: June 2011)

Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels.

scientific article

The AMPA receptor positive allosteric modulator S 47445 rescues in vivo CA3-CA1 long-term potentiation and structural synaptic changes in old mice.

scientific article published on 8 June 2017

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