List of works - Tom P Monie

A dimer of the Toll-like receptor 4 cytoplasmic domain provides a specific scaffold for the recruitment of signalling adaptor proteins

scientific article

A peptide motif in Raver1 mediates splicing repression by interaction with the PTB RRM2 domain

scientific article

Activating immunity: lessons from the TLRs and NLRs

scientific article published on 07 October 2009

Allergens as immunomodulatory proteins: the cat dander protein Fel d 1 enhances TLR activation by lipid ligands

scientific article published on 22 July 2013

Bioinformatic analysis of Toll-like receptor sequences and structures

scientific article published in January 2009

Blau syndrome polymorphisms in NOD2 identify nucleotide hydrolysis and helical domain 1 as signalling regulators

scientific article

CARD9 negatively regulates NLRP3-induced IL-1β production on Salmonella infection of macrophages

scientific article published on 27 September 2016

Caspase-8 functions as a key mediator of inflammation and pro-IL-1β processing via both canonical and non-canonical pathways

scientific article published on May 2015

Cell swelling and the NLRP3 inflammasome

scientific article published in March 2013

Comparative Genomic and Sequence Analysis Provides Insight into the Molecular Functionality of NOD1 and NOD2.

scientific article published on 7 October 2013

Computational analysis predicts the Kaposi's sarcoma-associated herpesvirus tegument protein ORF63 to be alpha helical

scientific article

Conformation of Polypyrimidine Tract Binding Protein in Solution

scientific article published on 01 June 2006

Elucidation of the MD-2/TLR4 interface required for signaling by lipid IVa.

scientific article

Engagement of nucleotide-binding oligomerization domain-containing protein 1 (NOD1) by receptor-interacting protein 2 (RIP2) is insufficient for signal transduction

scientific article

Identification and visualization of the dimerization initiation site of the prototype lentivirus, maedi visna virus: a potential GACG tetraloop displays structural homology with the alpha- and gamma-retroviruses

scientific article published in January 2005

Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex.

scientific article

Innate Immune Sensors and Gastrointestinal Bacterial Infections ⬇️

scientific article published on May 19, 2011

Insights into the molecular basis of the NOD2 signalling pathway

scientific article

Interaction between NOD2 and CARD9 involves the NOD2 NACHT and the linker region between the NOD2 CARDs and NACHT domain

scientific article published on 21 June 2014

International Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and disease

scientific article

Mice, men and the relatives: cross-species studies underpin innate immunity

scientific article published on April 2012

NLR activation takes a direct route

scientific article published on 08 February 2013

Oligonucleotide mapping of the core genomic RNA dimer linkage in human T-cell leukaemia virus type-1.

scientific article published on October 2001

Pathogen sensing by nucleotide-binding oligomerization domain-containing protein 2 (NOD2) is mediated by direct binding to muramyl dipeptide and ATP.

scientific article

Polymorphisms at amino acid residues 141 and 154 influence conformational variation in ovine PrP.

scientific article published on 14 July 2014

Salmonella infection induces recruitment of Caspase-8 to the inflammasome to modulate IL-1β production

scientific article

Structural insights into the transcriptional and translational roles of Ebp1

scientific article

Structure and RNA Interactions of the N-Terminal RRM Domains of PTB

scientific article published on 01 September 2004

Structure and regulation of cytoplasmic adapter proteins involved in innate immune signaling

scientific article published on January 2009

TRIL, a functional component of the TLR4 signaling complex, highly expressed in brain

scientific article

The N-terminal region of the human autophagy protein ATG16L1 contains a domain that folds into a helical structure consistent with formation of a coiled-coil

scientific article (publication date: 2013)

The human T-cell lymphotropic virus type-I dimerization initiation site forms a hairpin loop, unlike previously characterized retroviral dimerization motifs

scientific article

The immunoglobulin domain of the sodium channel β3 subunit contains a surface-localized disulfide bond that is required for homophilic binding

scientific article published on November 2012

The nucleotide-binding oligomerization domain-containing protein 1 (NOD1) polymorphism S7N does not affect receptor function

scientific article (publication date: 5 March 2014)

The polypyrimidine tract binding protein is a monomer.

scientific article published in December 2005

Viral inhibitory peptide of TLR4, a peptide derived from vaccinia protein A46, specifically inhibits TLR4 by directly targeting MyD88 adaptor-like and TRIF-related adaptor molecule

scientific article published on 27 August 2010

List of works by Tom P Monie

A dimer of the Toll-like receptor 4 cytoplasmic domain provides a specific scaffold for the recruitment of signalling adaptor proteins

A peptide motif in Raver1 mediates splicing repression by interaction with the PTB RRM2 domain

Activating immunity: lessons from the TLRs and NLRs

Allergens as immunomodulatory proteins: the cat dander protein Fel d 1 enhances TLR activation by lipid ligands

Bioinformatic analysis of Toll-like receptor sequences and structures

Blau syndrome polymorphisms in NOD2 identify nucleotide hydrolysis and helical domain 1 as signalling regulators

CARD9 negatively regulates NLRP3-induced IL-1β production on Salmonella infection of macrophages

Caspase-8 functions as a key mediator of inflammation and pro-IL-1β processing via both canonical and non-canonical pathways

Cell swelling and the NLRP3 inflammasome

Comparative Genomic and Sequence Analysis Provides Insight into the Molecular Functionality of NOD1 and NOD2.

Computational analysis predicts the Kaposi's sarcoma-associated herpesvirus tegument protein ORF63 to be alpha helical

Conformation of Polypyrimidine Tract Binding Protein in Solution

Elucidation of the MD-2/TLR4 interface required for signaling by lipid IVa.

Engagement of nucleotide-binding oligomerization domain-containing protein 1 (NOD1) by receptor-interacting protein 2 (RIP2) is insufficient for signal transduction

Identification and visualization of the dimerization initiation site of the prototype lentivirus, maedi visna virus: a potential GACG tetraloop displays structural homology with the alpha- and gamma-retroviruses

Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex.

Innate Immune Sensors and Gastrointestinal Bacterial Infections ⬇️

Insights into the molecular basis of the NOD2 signalling pathway

Interaction between NOD2 and CARD9 involves the NOD2 NACHT and the linker region between the NOD2 CARDs and NACHT domain

International Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and disease

Mice, men and the relatives: cross-species studies underpin innate immunity

NLR activation takes a direct route

Oligonucleotide mapping of the core genomic RNA dimer linkage in human T-cell leukaemia virus type-1.

Pathogen sensing by nucleotide-binding oligomerization domain-containing protein 2 (NOD2) is mediated by direct binding to muramyl dipeptide and ATP.

Polymorphisms at amino acid residues 141 and 154 influence conformational variation in ovine PrP.

Salmonella infection induces recruitment of Caspase-8 to the inflammasome to modulate IL-1β production

Structural insights into the transcriptional and translational roles of Ebp1

Structure and RNA Interactions of the N-Terminal RRM Domains of PTB

Structure and regulation of cytoplasmic adapter proteins involved in innate immune signaling

TRIL, a functional component of the TLR4 signaling complex, highly expressed in brain

The N-terminal region of the human autophagy protein ATG16L1 contains a domain that folds into a helical structure consistent with formation of a coiled-coil

The human T-cell lymphotropic virus type-I dimerization initiation site forms a hairpin loop, unlike previously characterized retroviral dimerization motifs

The immunoglobulin domain of the sodium channel β3 subunit contains a surface-localized disulfide bond that is required for homophilic binding

The nucleotide-binding oligomerization domain-containing protein 1 (NOD1) polymorphism S7N does not affect receptor function

The polypyrimidine tract binding protein is a monomer.

Viral inhibitory peptide of TLR4, a peptide derived from vaccinia protein A46, specifically inhibits TLR4 by directly targeting MyD88 adaptor-like and TRIF-related adaptor molecule