Search filters

List of works by Jeroen Demmers

A Proteome-wide screen for mammalian SxIP motif-containing microtubule plus-end tracking proteins

scientific article

A Testis-Specific Chaperone and the Chromatin Remodeler ISWI Mediate Repackaging of the Paternal Genome

scientific article published on 4 November 2015

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal

scientific journal article

A functional insulator screen identifies NURF and dREAM components to be required for enhancer-blocking

scientific article

A new function of ROD1 in nonsense-mediated mRNA decay

scientific article published on 21 March 2012

A novel complex, RUNX1-MYEF2, represses hematopoietic genes in erythroid cells

scientific article

A proteome comparison between human fetal and mature renal extracellular matrix identifies EMILIN1 as a regulator of renal epithelial cell adhesion

scientific article published on 25 July 2019

A systems approach to analyze transcription factors in mammalian cells

scientific article published on 10 August 2010

A20-binding inhibitor of nuclear factor-kappaB (NF-kappaB)-2 (ABIN-2) is an activator of inhibitor of NF-kappaB (IkappaB) kinase alpha (IKKalpha)-mediated NF-kappaB transcriptional activity

scientific article

ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN.

scientific article published on 15 May 2013

ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes

scientific journal article

Activin A suppresses osteoblast mineralization capacity by altering extracellular matrix (ECM) composition and impairing matrix vesicle (MV) production.

scientific article published on 17 June 2013

An Oct4-centered protein interaction network in embryonic stem cells

scientific article

An immunoaffinity purification method for the proteomic analysis of ubiquitinated protein complexes

scientific article published on 03 June 2013

An interaction network of mental disorder proteins in neural stem cells

scientific article published on 4 April 2017

BICD2, dynactin, and LIS1 cooperate in regulating dynein recruitment to cellular structures

scientific article

BRCA1185delAG tumors may acquire therapy resistance through expression of RING-less BRCA1

scientific article published on 25 July 2016

Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry

scientific article

Binding of carboxypeptidase N to fibrinogen and fibrin.

scientific article

CAMK2-Dependent Signaling in Neurons Is Essential for Survival

scientific article published on 07 May 2019

CFEOM1-associated kinesin KIF21A is a cortical microtubule growth inhibitor.

scientific article published on 10 October 2013

CLASPs attach microtubule plus ends to the cell cortex through a complex with LL5beta

scientific article

CS-05MUTATION SPECIFIC FUNCTIONS OF EGFR RESULT IN A MUTATION-SPECIFIC DOWNSTREAM PATHWAY ACTIVATION.

scientific article published in November 2014

CTCF regulates the local epigenetic state of ribosomal DNA repeats

scientific article

Combgap contributes to recruitment of Polycomb group proteins in Drosophila

scientific article published on 21 March 2016

Comparative proteomic profiling of human osteoblast-derived extracellular matrices identifies proteins involved in mesenchymal stromal cell osteogenic differentiation and mineralization

scientific article published on 8 March 2017

Control of developmentally primed erythroid genes by combinatorial co-repressor actions

scientific article

Correction: Detection of Alpha-Toxin and Other Virulence Factors in Biofilms of Staphylococcus aureus on Polystyrene and a Human Epidermal Model

scientific article published on 24 March 2016

DNA damage-induced histone H1 ubiquitylation is mediated by HUWE1 and stimulates the RNF8-RNF168 pathway.

scientific article published on 10 November 2017

DNA damage-induced replication stress results in PA200-proteasome-mediated degradation of acetylated histones

scientific article published on 13 August 2018

DNA dependent recruitment of DDX17 and other interacting proteins by the human androgen receptor

scientific article

DOC1-Dependent Recruitment of NURD Reveals Antagonism with SWI/SNF during Epithelial-Mesenchymal Transition in Oral Cancer Cells.

scientific article published in July 2017

Decreased mitochondrial respiration in aneurysmal aortas of Fibulin-4 mutant mice is linked to PGC1A regulation

scientific article published on 01 November 2018

Detection of Alpha-Toxin and Other Virulence Factors in Biofilms of Staphylococcus aureus on Polystyrene and a Human Epidermal Model

scientific article

Deubiquitylating enzyme UBP64 controls cell fate through stabilization of the transcriptional repressor tramtrack

scientific article published on 26 December 2007

Differential proteomics based on 18O labeling to determine the cyclin dependent kinase 9 interactome

scientific journal article

Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

scientific article

Distinct and overlapping DNMT1 interactions with multiple transcription factors in erythroid cells: Evidence for co-repressor functions

scientific article published on 28 September 2016

Drosophila transcription factor Tramtrack69 binds MEP1 to recruit the chromatin remodeler NuRD.

scientific article

Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4

scientific article

Dynamic microtubules catalyze formation of navigator-TRIO complexes to regulate neurite extension

scientific article

Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity

scientific article

Electrospray ionization mass spectrometry as a tool to analyze hydrogen/deuterium exchange kinetics of transmembrane peptides in lipid bilayers.

scholarly article

Elevated Plasma Cardiac Troponin T Levels Caused by Skeletal Muscle Damage in Pompe Disease

scientific article published on 19 January 2016

Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability

scientific article published on 09 June 2021

Erythropoietic defect associated with reduced cell proliferation in mice lacking the 26S proteasome shuttling factor Rad23b

scientific article

Estrogen-related receptor beta interacts with Oct4 to positively regulate Nanog gene expression

scientific journal article

Excessive exosome release is the pathogenic pathway linking a lysosomal deficiency to generalized fibrosis

scientific article published on 17 July 2019

Exosome-mediated transmission of hepatitis C virus between human hepatoma Huh7.5 cells.

scientific article published on 22 July 2013

Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors

scientific article published on April 2009

FACT subunit Spt16 controls UVSSA recruitment to lesion-stalled RNA Pol II and stimulates TC-NER

scientific article published on 01 May 2019

Factors affecting gas-phase deuterium scrambling in peptide ions and their implications for protein structure determination.

scientific article

Five friends of methylated chromatin target of protein-arginine-methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation

scientific article

Friend of Prmt1, a novel chromatin target of protein arginine methyltransferases

scientific article

Further analysis of the involvement of the envelope anion channel PIRAC in chloroplast protein import

scientific article published on 01 June 2000

GSK3β phosphorylates newly identified site in the proline-alanine-rich region of cardiac myosin-binding protein C and alters cross-bridge cycling kinetics in human: short communication

scientific article

Generation of a biotinylatable Sox2 mouse model to identify Sox2 complexes in vivo.

scientific article published on 30 January 2018

Global Proteome and Ubiquitinome Changes in the Soluble and Insoluble Fractions of Q175 Huntington Mice Brains

scientific article published on 28 May 2019

Global quantitative proteomics reveals novel factors in the ecdysone signaling pathway in Drosophila melanogaster.

scientific article published on 14 January 2015

Guide-free Cas9 from pathogenic Campylobacter jejuni bacteria causes severe damage to DNA

scientific article published on 17 June 2020

HSF2BP Interacts with a Conserved Domain of BRCA2 and Is Required for Mouse Spermatogenesis

scientific article published on 01 June 2019

Heterogeneous clinical phenotypes and cerebral malformations reflected by rotatin cellular dynamics

scientific article published on 01 April 2019

Histone chaperone NAP1 mediates sister chromatid resolution by counteracting protein phosphatase 2A

scientific article (publication date: 2013)

Histone chaperones ASF1 and NAP1 differentially modulate removal of active histone marks by LID-RPD3 complexes during NOTCH silencing

scientific article published in September 2009

Homozygous Mutations in CSF1R Cause a Pediatric-Onset Leukoencephalopathy and Can Result in Congenital Absence of Microglia

scientific article published on 11 April 2019

Human osteoblast-derived extracellular matrix with high homology to bone proteome is osteopromotive.

scientific article published on 18 April 2018

Identification by a differential proteomic approach of the induced stress and redox proteins by resveratrol in the normal and diabetic rat heart.

scientific article published on 11 January 2008

Identification of Chloride Intracellular Channel Protein 3 as a Novel Gene Affecting Human Bone Formation

scientific article published on 28 April 2017

Identification of Full-Length Wild-Type and Mutant Huntingtin Interacting Proteins by Crosslinking Immunoprecipitation in Mice Brain Cortex

scientific article published on 01 January 2021

Identification of delta/notch-like epidermal growth factor-related receptor as the Tr antigen in paraneoplastic cerebellar degeneration

scientific article

Identification of differential protein interactors of lamin A and progerin

scientific article

Identification of fibrin clot-bound plasma proteins

scientific article

Identification of protein receptors for coronaviruses by mass spectrometry

scientific article published on January 2015

Identification of the (Pro)renin Receptor as a Novel Regulator of Low-Density Lipoprotein Metabolism

scientific article published on 18 November 2015

Identifying Cystogenic Paracrine Signaling Molecules in Cyst Fluid of Patients with Polycystic Kidney Disease

scientific article published on 07 November 2018

Improvement of ubiquitylation site detection by Orbitrap mass spectrometry.

scientific article published on 6 November 2017

Independent Mechanisms Target SMCHD1 to Trimethylated Histone H3 Lysine 9-Modified Chromatin and the Inactive X Chromosome.

scientific article

Integrative analysis of genomics and proteomics data on clinical breast cancer tissue specimens extracted with acid guanidinium thiocyanate-phenol-chloroform.

scientific article

Interaction of the K+ channel KcsA with membrane phospholipids as studied by ESI mass spectrometry

scientific article published in April 2003

Interactions between phage-shock proteins in Escherichia coli

scientific article

Interfacial anchor properties of tryptophan residues in transmembrane peptides can dominate over hydrophobic matching effects in peptide-lipid interactions

scientific article published in May 2003

Interfacial positioning and stability of transmembrane peptides in lipid bilayers studied by combining hydrogen/deuterium exchange and mass spectrometry

scientific article published on 2 July 2001

Isolation of Functional Tubulin Dimers and of Tubulin-Associated Proteins from Mammalian Cells

scientific article

Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators.

scientific article published on 16 May 2010

Liprin-α2 promotes the presynaptic recruitment and turnover of RIM1/CASK to facilitate synaptic transmission

scientific article published on June 2013

Locus-specific proteomics by TChP: targeted chromatin purification

scientific article published in August 2013

Loss of SMPD4 Causes a Developmental Disorder Characterized by Microcephaly and Congenital Arthrogryposis

scientific article published on 05 September 2019

Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases

scientific journal article

Mass spectrometric identification of human prostate cancer-derived proteins in serum of xenograft-bearing mice

scientific article published on 19 May 2006

Mediator complex interaction partners organize the transcriptional network that defines neural stem cells.

scientific article

MiR-17/20/93/106 promote hematopoietic cell expansion by targeting sequestosome 1-regulated pathways in mice

scientific article

Motor neuron disease-associated mutant vesicle-associated membrane protein-associated protein (VAP) B recruits wild-type VAPs into endoplasmic reticulum-derived tubular aggregates.

scientific article published on September 2007

Mutation specific functions of EGFR result in a mutation-specific downstream pathway activation

scientific article published on 5 March 2015

Myosin V regulates synaptopodin clustering and localization in the dendrites of hippocampal neurons

scientific article published on 22 August 2019

NLS-tagging: an alternative strategy to tag nuclear proteins

scientific article published on 26 September 2014

NMDA receptor activation suppresses microtubule growth and spine entry

scientific journal article

NP-40 reduces contamination by endogenous biotinylated carboxylases during purification of biotin tagged nuclear proteins

scientific article published on 7 March 2013

Nipbl Interacts with Zfp609 and the Integrator Complex to Regulate Cortical Neuron Migration

scientific article

Nuclear receptors TR2 and TR4 recruit multiple epigenetic transcriptional corepressors that associate specifically with the embryonic β-type globin promoters in differentiated adult erythroid cells

scientific article

Nucleotide biosynthetic enzyme GMP synthase is a TRIM21-controlled relay of p53 stabilization

scientific article published on 23 January 2014

On the Mechanism of Hyperthermia-Induced BRCA2 Protein Degradation

Phospho-Ku70 induced by DNA damage interacts with RNA Pol II and promotes the formation of phospho-53BP1 foci to ensure optimal cNHEJ

scientific article published on 01 November 2021

Phosphorylation-mediated control of histone chaperone ASF1 levels by Tousled-like kinases

scientific article

Photo-crosslinking analysis of preferential interactions between a transmembrane peptide and matching lipids

scientific article published in April 2004

Polycomblike 2 facilitates the recruitment of PRC2 Polycomb group complexes to the inactive X chromosome and to target loci in embryonic stem cells

scientific article

Preconception folic acid use influences the follicle fluid proteome

scientific article published on 3 July 2015

Protein 4.1R binds to CLASP2 and regulates dynamics, organization and attachment of microtubules to the cell cortex

scientific article published on 13 August 2013

Protein Phosphatase 2B Dual Function Facilitates Synaptic Integrity and Motor Learning

scientific article published on 21 May 2021

Proteins that bind regulatory regions identified by histone modification chromatin immunoprecipitations and mass spectrometry.

scientific article published on 20 May 2015

Proteomic analysis of FOXP proteins reveals interactions between cortical transcription factors associated with neurodevelopmental disorders

scientific article

Proteomic analysis of FOXP proteins reveals interactions between cortical transcription factors associated with neurodevelopmental disorders

scientific article published on 26 June 2018

Proteomic analysis of the microenvironment of developing oocytes

scientific article published in May 2012

Proteomic profiling of the spinal cord in ALS: decreased ATP5D levels suggest synaptic dysfunction in ALS pathogenesis

scientific article published on 29 November 2016

Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth

scientific article

Proteomics analysis of Ring1B/Rnf2 interactors identifies a novel complex with the Fbxl10/Jhdm1B histone demethylase and the Bcl6 interacting corepressor

scientific journal article

Proteomics of Urinary Vesicles Links Plakins and Complement to Polycystic Kidney Disease

scientific article published on 3 March 2016

Publisher Correction: Mediator complex interaction partners organize the transcriptional network that defines neural stem cells

scientific article published on 22 July 2019

Quantitative Proteomics Reveals Extensive Changes in the Ubiquitinome after Perturbation of the Proteasome by Targeted dsRNA-Mediated Subunit Knockdown in Drosophila

scientific article

RAD51AP1 is a structure-specific DNA binding protein that stimulates joint molecule formation during RAD51-mediated homologous recombination

scientific article published in November 2007

REX1 is the critical target of RNF12 in imprinted X chromosome inactivation in mice

scientific article published in Nature Communications

RIF1 promotes replication fork protection and efficient restart to maintain genome stability

scientific article published on 23 July 2019

RNF12 initiates X-chromosome inactivation by targeting REX1 for degradation

scientific article published on 29 April 2012

RYBP-PRC1 Complexes Mediate H2A Ubiquitylation at Polycomb Target Sites Independently of PRC2 and H3K27me3.

scientific article

RYBP-PRC1 complexes mediate H2A ubiquitylation at polycomb target sites independently of PRC2 and H3K27me3

scientific article

Rab6 regulates transport and targeting of exocytotic carriers

scientific article published on August 2007

Rab6, Rab8, and MICAL3 cooperate in controlling docking and fusion of exocytotic carriers

scientific article published on 19 May 2011

Recovery in the Myogenic Program of Congenital Myotonic Dystrophy Myoblasts after Excision of the Expanded (CTG)n Repeat

scientific article published on 13 November 2019

Remodelers organize cellular chromatin by counteracting intrinsic histone-DNA sequence preferences in a class-specific manner

scientific article published on 28 November 2011

Return to quiescence of mouse neural stem cells by degradation of a proactivation protein.

scientific article

SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase

scientific article

STIM1 is a MT-plus-end-tracking protein involved in remodeling of the ER.

scientific article

Semi-quantitative proteomics of mammalian cells upon short-term exposure to non-ionizing electromagnetic fields.

scientific article

Sin3a is essential for the genome integrity and viability of pluripotent cells

scientific article published on 20 December 2011

Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes

scientific journal article

Sp1/Sp3 transcription factors regulate hallmarks of megakaryocyte maturation and platelet formation and function.

scientific article

Subdomain-mediated axon-axon signaling and chemoattraction cooperate to regulate afferent innervation of the lateral habenula

scientific article published in July 2014

Subunits of the histone chaperone CAF1 also mediate assembly of protamine-based chromatin

scientific article published on 27 June 2013

TAF10 Interacts with the GATA1 Transcription Factor and Controls Mouse Erythropoiesis.

scientific article published on 13 April 2015

TRAK/Milton motor-adaptor proteins steer mitochondrial trafficking to axons and dendrites

scientific journal article

Talking to chromatin: post-translational modulation of polycomb group function.

scientific article published on September 2009

Targeted Proteomics for the Detection of SARS-CoV-2 Proteins

scientific article published on 24 April 2020

Targeted proteomics as a tool to detect SARS-CoV-2 proteins in clinical specimens

scientific article published on 11 November 2021

The BAF complex interacts with Pax6 in adult neural progenitors to establish a neurogenic cross-regulatory transcriptional network.

scientific article published on 08 August 2013

The CUE1 domain of the SNF2-like chromatin remodeler SMARCAD1 mediates its association with KRAB-associated protein 1 (KAP1) and KAP1 target genes

scientific article

The DNA binding factor Hmg20b is a repressor of erythroid differentiation

scientific article

The GRIP1/14-3-3 pathway coordinates cargo trafficking and dendrite development

scientific article

The core spliceosome as target and effector of non-canonical ATM signalling.

scientific article

The dual role of LSD1 and HDAC3 in STAT5-dependent transcription is determined by protein interactions, binding affinities, motifs and genomic positions.

scientific article published on 19 September 2016

The expanded clinical spectrum of anti-GABABR encephalitis and added value of KCTD16 autoantibodies.

scientific article

The lethal response to Cdk1 inhibition depends on sister chromatid alignment errors generated by KIF4 and isoform 1 of PRC1.

scientific article

The splicing factor XAB2 interacts with ERCC1-XPF and XPG for R-loop processing

scientific article published on 26 May 2021

Transcription-coupled DNA–protein crosslink repair by CSB and CRL4CSA-mediated degradation

scientific article published in 2024

Transcription-independent function of Polycomb group protein PSC in cell cycle control

scientific article

UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair

scientific article

Unraveling the human bone microenvironment beyond the classical extracellular matrix proteins: a human bone protein library.

scientific article

VEGFR2 translocates to the nucleus to regulate its own transcription

scientific article

dKDM2 couples histone H2A ubiquitylation to histone H3 demethylation during Polycomb group silencing

scientific article

Paulina is supported by:

About Paulina

Help