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List of works by Marije Koenders

1.56 Synergism between GM-CSF and IL-17 causes enhanced joint pathology via the production of IL-6 and IL-23

scholarly article by Annemarie E M van Nieuwenhuijze et al published 31 January 2014 in Annals of the Rheumatic Diseases

12/15-lipoxygenase counteracts inflammation and tissue damage in arthritis

scientific article published on 12 August 2009

4.8 Role of Toll-like receptor 9 in the pathogenesis of inflammatory autoimmune arthritis and osteoclast activation

A1.22 IL-22 Drives the initiation and augmentation of TH17-dependent experimental arthritis

A1.81 Mincle is not essential in T-cell independent arthritis models

A2.11 Involvement of the Nucleic Acid Recognising Toll-Like Receptors TLR7 and TLR9 in the Pathogenesis of Erosive Arthritis

A3.5 Combination Blocking of IL-6 and IL-21 in Experimental Arthritis Inhibits their Redundant Role in Th17-Driven Joint Pathology

scholarly article by Marije Koenders et al published 25 February 2013 in Annals of the Rheumatic Diseases

A8.29 Commensal intestinal microbiota drives spontaneous interleukin-1- and T helper 17-mediated arthritis in mice

Amplifying elements of arthritis and joint destruction

scientific article published on November 2007

Anti IL-17A therapy inhibits bone loss in TNF-α-mediated murine arthritis by modulation of the T-cell balance

scientific article published on 20 December 2011

Anti-interleukin 17A therapy inhibits tumour necrosis factor-mediated bone loss by modulation of T cell balance

Blocking of interleukin-17 during reactivation of experimental arthritis prevents joint inflammation and bone erosion by decreasing RANKL and interleukin-1.

scientific article published on July 2005

Combined blockade of granulocyte-macrophage colony stimulating factor and interleukin 17 pathways potently suppresses chronic destructive arthritis in a tumour necrosis factor -independent mouse model

article

Deficiency of Nrf2 Accelerates the Effector Phase of Arthritis and Aggravates Joint Disease

scientific article published on 25 May 2011

Destructive role of myeloid differentiation factor 88 and protective role of TRIF in interleukin-17-dependent arthritis in mice

scientific article published on 06 December 2011

Different amplifying mechanisms of interleukin-17 and interferon-gamma in Fcgamma receptor-mediated cartilage destruction in murine immune complex-mediated arthritis

scientific article

Engagement of fatty acids with Toll-like receptor 2 drives interleukin-1β production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis

scientific article

Essential role of microRNA-155 in the pathogenesis of autoimmune arthritis in mice

scientific article published on 01 May 2011

Exposure to Candida albicans polarizes a T-cell driven arthritis model towards Th17 responses, resulting in a more destructive arthritis

scientific article (publication date: 2012)

GM-CSF as a therapeutic target in inflammatory diseases

scientific article published on 08 August 2013

Glucose kinetics in the collagen-induced arthritis model: an all-in-one model to assess both efficacy and metabolic side effects of glucocorticoids

scientific article

IL-21 induces socs-mediated suppression of TLR triggering but aggravates TH17-driven destructive arthritis

article by Renoud J Marijnissen et al published February 2012 in Annals of the Rheumatic Diseases

In Vivo Molecular Imaging of Cathepsin and Matrix Metalloproteinase Activity Discriminates between Arthritic and Osteoarthritic Processes in Mice

scientific article published on 01 January 2014

Increased expression of interleukin-22 by synovial Th17 cells during late stages of murine experimental arthritis is controlled by interleukin-1 and enhances bone degradation

scientific article published on 01 October 2011

Increased innate immune responses by interleukin-22 contributes to the inflammatory process in rheumatoid arthritis

article

Induction of cartilage damage by overexpression of T cell interleukin-17A in experimental arthritis in mice deficient in interleukin-1.

scientific article published in March 2005

Inflammation-dependent secretion and splicing of IL-32{gamma} in rheumatoid arthritis

scientific article

Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta

scientific article published on December 2009

Interleukin 32 (IL-32) contains a typical α-helix bundle structure that resembles focal adhesion targeting region of focal adhesion kinase-1.

scientific article

Interleukin-1 drives pathogenic Th17 cells during spontaneous arthritis in interleukin-1 receptor antagonist-deficient mice

scientific article published on 01 November 2008

Interleukin-17 receptor deficiency results in impaired synovial expression of interleukin-1 and matrix metalloproteinases 3, 9, and 13 and prevents cartilage destruction during chronic reactivated streptococcal cell wall-induced arthritis.

scientific article

Interleukin-18 promotes joint inflammation and induces interleukin-1-driven cartilage destruction

scientific article

Interleukin-21 receptor deficiency increases the initial toll-like receptor 2 response but protects against joint pathology by reducing Th1 and Th17 cells during streptococcal cell wall arthritis

scientific article published on April 2014

Local activation of STAT-1 and STAT-3 in the inflamed synovium during zymosan-induced arthritis: exacerbation of joint inflammation in STAT-1 gene-knockout mice

scientific article published in June 2004

Local interleukin-1-driven joint pathology is dependent on toll-like receptor 4 activation

scientific article

Monitoring the effects of dexamethasone treatment by MRI using in vivo iron oxide nanoparticle-labeled macrophages

scientific article

Monocytic cell differentiation from band-stage neutrophils under inflammatory conditions via MKK6 activation

scientific article published on 11 September 2014

Murine Borrelia arthritis is highly dependent on ASC and caspase-1, but independent of NLRP3.

scientific article published on 13 November 2012

NIR-fluorescence imaging points at a role for matrix-metalloproteinases in causing irreversible cartilage damage during collagen-induced arthritis

Periodontal pathogens amplify arthritic bone erosion by reducing the TH2 response and promoting a toll-like receptor 2-dependent TH17 phenotype

Periodontal pathogens directly promote autoimmune experimental arthritis by inducing a TLR2- and IL-1-driven Th17 response

scientific article published on 28 March 2014

Potential new targets in arthritis therapy: interleukin (IL)-17 and its relation to tumour necrosis factor and IL-1 in experimental arthritis.

scientific article published on November 2006

Reply: To PMID 23860661.

scientific article published in December 2013

Role of interleukin 17 in arthritis chronicity through survival of synoviocytes via regulation of synoviolin expression

scientific article

Shift from toll-like receptor 2 (TLR-2) toward TLR-4 dependency in the erosive stage of chronic streptococcal cell wall arthritis coincident with TLR-4-mediated interleukin-17 production

scientific article published in December 2008

Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis

scientific article published on January 2008

Supplementation of diet with non-digestible oligosaccharides alters the intestinal microbiota, but not arthritis development, in IL-1 receptor antagonist deficient mice

scientific article published on 08 July 2019

T cell dependence of chronic destructive murine arthritis induced by repeated local activation of toll-like receptor–driven pathways: Crucial role of both interleukin-1β and interleukin-17

scientific article published on 01 January 2008

T cell lessons from the rheumatoid arthritis synovium SCID mouse model: CD3-rich synovium lacks response to CTLA-4ig but is successfully treated by interleukin-17 neutralization

article

The CO-releasing molecule CORM-3 protects against articular degradation in the K/BxN serum transfer arthritis model

scientific article published on 23 February 2010

The Th17 pathway as a therapeutic target in rheumatoid arthritis and other autoimmune and inflammatory disorders.

scientific article published on October 2013

The anti-CD20 antibody rituximab reduces the Th17 cell response

article

The role of T-cell interleukin-17 in conducting destructive arthritis: lessons from animal models

scientific article

Toll-like receptor 2 controls acute immune complex-driven arthritis in mice by regulating the inhibitory Fcγ receptor IIB.

scientific article published in October 2013

Translational mini-review series on Th17 cells: are T helper 17 cells really pathogenic in autoimmunity?

scientific article

Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion

scientific article published on February 2004

Tumour necrosis factor alpha-driven IL-32 expression in rheumatoid arthritis synovial tissue amplifies an inflammatory cascade ⬇️

scholarly article by B. Heinhuis et al published April 2011 in Annals of the Rheumatic Diseases

Up-Regulation of the Inflammatory Response by Ovariectomy in Collagen-Induced Arthritis. Effects of Tin Protoporphyrin IX

scientific article published on 01 December 2011

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