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List of works by Kevan Hartshorn

A Unique Sugar-binding Site Mediates the Distinct Anti-influenza Activity of Pig Surfactant Protein D

scientific article

Absence of SP-A modulates innate and adaptive defense responses to pulmonary influenza infection

scientific article published in March 2002

Acquired Disorders of Phagocyte Function Complicating Medical and Surgical Illnesses ⬇️

scientific article published on November 5, 2001

Activity of interferons alpha, beta, and gamma against human immunodeficiency virus replication in vitro

scientific article

Antibody-dependent cell-mediated cytotoxicity against cells infected with the human immunodeficiency virus

scientific article

Bovine conglutinin (BC) mRNA expressed in liver: cloning and characterization of the BC cDNA reveals strong homology to surfactant protein-D.

scientific article published on April 1994

CK2 in Cancer: Cellular and Biochemical Mechanisms and Potential Therapeutic Target.

scientific article

Circulating neutrophil CD18 receptor expression and ischemic flap neutrophil infiltration in a guinea pig model

scientific article published on 01 March 2000

Clinical Update: Colon, Rectal, and Anal Cancers ⬇️

scientific article published on November 1, 2012

Collectin 11 (CL-11, CL-K1) is a MASP-1/3-associated plasma collectin with microbial-binding activity

scientific article published on 18 October 2010

Collectins and pulmonary innate immunity

scientific article (publication date: February 2000)

Colon, rectal, and anal cancers.

scientific article published on February 2009

Comparative glycomics of leukocyte glycosaminoglycans ⬇️

scientific article published on April 2, 2013

Complementation of pulmonary abnormalities in SP-D(-/-) mice with an SP-D/conglutinin fusion protein

scientific article published on 15 April 2002

Correction of pulmonary abnormalities in Sftpd-/- mice requires the collagenous domain of surfactant protein D.

scientific article

Critical role for cross-linking of trimeric lectin domains of surfactant protein D in antiviral activity against influenza A virus

scientific article

Critical role of C-terminal residues of the Alzheimer's associated β-amyloid protein in mediating antiviral activity and modulating viral and bacterial interactions with neutrophils

scientific article

Critical role of serpinB1 in regulating inflammatory responses in pulmonary influenza infection

scientific article

Development of chimeric collectins with enhanced activity against influenza A virus.

scientific article published in January 2000

Distinctive anti-influenza properties of recombinant collectin 43.

scientific article

Dose-painted intensity-modulated radiation therapy for anal cancer: a multi-institutional report of acute toxicity and response to therapy

scientific article

Effect of nisoldipine on priming and activation of the human neutrophil respiratory burst

scientific article published on 01 August 1990

Effects of serum amyloid protein A on influenza A virus replication and viral interactions with neutrophils

scientific article published on 17 November 2020

Enhancement of antiviral activity of collectin trimers through cross-linking and mutagenesis of the carbohydrate recognition domain

scientific article published on 24 December 2009

Evidence for a protective role of pulmonary surfactant protein D (SP-D) against influenza A viruses.

scientific article

FABP5 deficiency enhances susceptibility to H1N1 influenza A virus-induced lung inflammation

scientific article published on 26 April 2013

Failure of oral nitrate and calcium channel blocker therapy to prevent 5-fluorouracil-related myocardial ischemia: a case report

scientific article published on January 1999

GM-CSF modulates pulmonary resistance to influenza A infection.

scientific article published on 08 September 2011

High molecular weight constituents of cranberry interfere with influenza virus neuraminidase activity in vitro

scientific article published on 15 May 2012

Histone H4 directly stimulates neutrophil activation through membrane permeabilization

scientific article published on 17 August 2020

Human H-ficolin inhibits replication of seasonal and pandemic influenza A viruses

scientific article

Human defensins and LL-37 in mucosal immunity.

scientific article published on 06 October 2009

Human mannose-binding protein functions as an opsonin for influenza A viruses ⬇️

scientific article published on April 1, 1993

Impact of neutrophils on antiviral activity of human bronchoalveolar lavage fluid

scientific article published on 24 August 2007

In vivo correlation of neutrophil receptor expression, ischemia-reperfusion injury, and selective 5-lipoxygenase inhibition in guinea pigs.

scientific article published on December 1998

Increased antiviral and opsonic activity of a highly multimerized collectin chimera

scientific article published in August 2001

Increasing antiviral activity of surfactant protein d trimers by introducing residues from bovine serum collectins: dissociation of mannan-binding and antiviral activity

scientific article published on July 2010

Influenza a viruses upregulate neutrophil toll-like receptor 2 expression and function

scientific article published in February 2006

Innate immune response of human alveolar macrophages during influenza A infection

scientific article (publication date: 2012)

Innate immune response to influenza A virus in differentiated human alveolar type II cells

scientific article published on 14 January 2011

Integrated Omics and Computational Glycobiology Reveal Structural Basis for Influenza A Virus Glycan Microheterogeneity and Host Interactions.

scientific article published on 16 March 2016

Interactions of alpha-, beta-, and theta-defensins with influenza A virus and surfactant protein D.

scientific article

Interactions of influenza A virus with sialic acids present on porcine surfactant protein D.

scientific article published on 12 December 2003

Interferon-alpha enhances neutrophil respiratory burst responses to stimulation with influenza A virus and FMLP.

scientific article published on October 1994

Introduction of N-linked glycans in the lectin domain of surfactant protein D: impact on interactions with influenza A viruses.

scientific article published on 13 April 2011

Lack of the pattern recognition molecule mannose-binding lectin increases susceptibility to influenza A virus infection

scientific article

Ligand specificity of human surfactant protein D: expression of a mutant trimeric collectin that shows enhanced interactions with influenza A virus

scientific article

Lung and salivary scavenger receptor glycoprotein-340 contribute to the host defense against influenza A viruses

scientific article

Mannose-binding lectin binds to amyloid β protein and modulates inflammation

scientific article published on 27 March 2012

Mechanism of binding of surfactant protein D to influenza A viruses: importance of binding to haemagglutinin to antiviral activity.

scientific article published on October 2000

Monoclonal antibody-assisted structure-function analysis of the carbohydrate recognition domain of surfactant protein D

scientific article

Multiple components contribute to ability of saliva to inhibit influenza viruses

scientific article

Mutagenesis of surfactant protein D informed by evolution and x-ray crystallography enhances defenses against influenza A virus in vivo

scientific article

New look at an old problem: bacterial superinfection after influenza

scientific article published on 17 December 2009

Novel strategies for prevention and treatment of influenza.

scientific article

Nrf2 protects human alveolar epithelial cells against injury induced by influenza A virus ⬇️

scientific article published on June 6, 2012

Partial purification and identification of an immunosuppressive factor in AIDS sera.

scientific article

Phosphatidylglycerol suppresses influenza A virus infection

scientific article

Porcine surfactant protein D is N-glycosylated in its carbohydrate recognition domain and is assembled into differently charged oligomers

scientific article published on 01 June 2002

Raised plasma parathyroid hormone related peptide in gastric adenocarcinoma

scientific article published in August 2000

Randomized controlled trial of a video decision support tool for cardiopulmonary resuscitation decision making in advanced cancer

scientific article

Recombinant chimeric lectins consisting of mannose-binding lectin and L-ficolin are potent inhibitors of influenza A virus compared with mannose-binding lectin

scientific article published on 28 October 2010

Recombinant human interferon alfa-A suppresses HTLV-III replication in vitro.

scientific article published in March 1985

Reduced influenza viral neutralizing activity of natural human trimers of surfactant protein D.

scientific article published on 5 February 2007

Respiratory innate immune proteins differentially modulate the neutrophil respiratory burst response to influenza A virus

scientific article published on 10 June 2005

Review: Defensins and cathelicidins in lung immunity.

scientific article published on 23 April 2010

Review: Structural determinants of pattern recognition by lung collectins.

scientific article published on 27 April 2010

Role of surfactant protein A and D (SP-A and SP-D) in human antiviral host defense

scientific article published on January 2010

Role of viral hemagglutinin glycosylation in anti-influenza activities of recombinant surfactant protein D

scientific article

Site-directed mutagenesis of Cys-15 and Cys-20 of pulmonary surfactant protein D. Expression of a trimeric protein with altered anti-viral properties

scientific article

Species differences in the carbohydrate binding preferences of surfactant protein D.

scientific article published on 02 March 2006

Surfactant protein D binds to human immunodeficiency virus (HIV) envelope protein gp120 and inhibits HIV replication

scientific article

Synergistic inhibition of human immunodeficiency virus in vitro by azidothymidine and recombinant alpha A interferon.

scientific article published on February 1987

Systemic neutrophil intrinsic 5-lipoxygenase activity and CD18 receptor expression linked to reperfusion injury

scientific article published on September 1998

The Role of Antimicrobial Peptides in Influenza Virus Infection and Their Potential as Antiviral and Immunomodulatory Therapy

scientific article

The ability of pandemic influenza virus hemagglutinins to induce lower respiratory pathology is associated with decreased surfactant protein D binding

scientific article

The human cathelicidin LL-37 inhibits influenza A viruses through a mechanism distinct from that of surfactant protein D or defensins

scientific article published on 10 October 2012

Viral aggregating and opsonizing activity in collectin trimers

scientific article

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