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List of works by Paul A. Ramsland

A Computational Approach for Exploring Carbohydrate Recognition by Lectins in Innate Immunity ⬇️

scientific article published on June 28, 2011

A Conserved Host and Pathogen Recognition Site on Immunoglobulins: Structural and Functional Aspects ⬇️

scientific article published on January 1, 2012

A Possible Role for Metallic Ions in the Carbohydrate Cluster Recognition Displayed by a Lewis Y Specific Antibody

scientific article

A common mechanism of clinical HIV-1 resistance to the CCR5 antagonist maraviroc despite divergent resistance levels and lack of common gp120 resistance mutations

scientific article published on 20 April 2013

A common site of the Fc receptor gamma subunit interacts with the unrelated immunoreceptors FcalphaRI and FcepsilonRI.

scientific article published on 19 April 2006

A double mutation of MBP83–99 peptide induces IL-4 responses and antagonizes IFN-γ responses

article

A glycopeptide in complex with MHC class I uses the GalNAc residue as an anchor

scientific article

Acquisition of Functional Antibodies That Block the Binding of Erythrocyte-Binding Antigen 175 and Protection Against Plasmodium falciparum Malaria in Children

scientific article published on July 2015

Allosteric modulation of the HIV-1 gp120-gp41 association site by adjacent gp120 variable region 1 (V1) N-glycans linked to neutralization sensitivity

scientific article

Altered peptide ligands of myelin basic protein ( MBP87-99 ) conjugated to reduced mannan modulate immune responses in mice

article

Alternative coreceptor requirements for efficient CCR5- and CXCR4-mediated HIV-1 entry into macrophages

scientific article

An FcgammaRIIa-binding peptide that mimics the interaction between FcgammaRIIa and IgG.

scientific article

An altered and more efficient mechanism of CCR5 engagement contributes to macrophage tropism of CCR5-using HIV-1 envelopes

scientific article

Antibody Recognition of Cancer-Related Gangliosides and Their Mimics Investigated Using in silico Site Mapping ⬇️

scientific article published on April 20, 2012

Antibody recognition of aberrant glycosylation on the surface of cancer cells

scientific article published on 4 November 2016

Antibody recognition of bacterial surfaces and extracellular polysaccharides

scientific article published on 21 December 2019

Antibody-Carbohydrate Recognition from Docked Ensembles Using the AutoMap Procedure

scientific article published on January 2015

Antimicrobial and immune modulatory effects of lactic acid and short chain fatty acids produced by vaginal microbiota associated with eubiosis and bacterial vaginosis

scientific article

AutoMap: a tool for analyzing protein-ligand recognition using multiple ligand binding modes.

scientific article published on 8 January 2013

Autoantibody-catalyzed hydrolysis of amyloid beta peptide

scientific article

Binding of nascent collagen by amyloidogenic light chains and amyloid fibrillogenesis in monolayers of human fibrocytes

scientific article published on July 2000

BioStructMap: a Python tool for integration of protein structure and sequence-based features.

scientific article published in November 2018

Blood brothers: carbohydrates in xenotransplantation and cancer immunotherapy

scientific article published on August 2005

Bovine IgM antibodies with exceptionally long complementarity-determining region 3 of the heavy chain share unique structural properties conferring restricted VH + Vlambda pairings.

scientific article

CD4-binding site alterations in CCR5-using HIV-1 envelopes influencing gp120-CD4 interactions and fusogenicity

scientific article published on 8 January 2011

Carbohydrate residues downstream of the terminal Galalpha(1,3)Gal epitope modulate the specificity of xenoreactive antibodies.

scientific article published on 28 August 2007

Carbohydrate-mimetic peptides: structural aspects of mimicry and therapeutic implications.

scientific article published on February 2011

Carbohydrates in Cyberspace

scientific article published on 10 June 2015

Challenges and advances in computational docking: 2009 in review ⬇️

scientific article published on October 23, 2010

Characterization of a unique conformational epitope on free immunoglobulin kappa light chains that is recognized by an antibody with therapeutic potential ⬇️

scientific article published on April 3, 2011

Cold-induced precipitation of a monoclonal IgM: a negative activation enthalpy reaction

scientific article published on 4 January 2013

Comparison of the three-dimensional structures of a human Bence-Jones dimer crystallized on Earth and aboard US Space Shuttle Mission STS-95

scientific article (publication date: 2003)

Conformational alterations in the CD4 binding cavity of HIV-1 gp120 influencing gp120-CD4 interactions and fusogenicity of HIV-1 envelopes derived from brain and other tissues

scientific article

Construction of single-chain Fv with two possible CDR3H conformations but similar inter-molecular forces that neutralize bovine herpesvirus 1.

scientific article

Covariance of charged amino acids at positions 322 and 440 of HIV-1 Env contributes to coreceptor specificity of subtype B viruses, and can be used to improve the performance of V3 sequence-based coreceptor usage prediction algorithms

scientific article

Cross-species analysis of Fc engineered anti-Lewis-Y human IgG1 variants in human neonatal receptor transgenic mice reveal importance of S254 and Y436 in binding human neonatal Fc receptor

scientific article published on 30 March 2016

Crystal structure of a glycosylated Fab from an IgM cryoglobulin with properties of a natural proteolytic antibody

scientific article published on May 2006

Crystal structures of human antibodies: a detailed and unfinished tapestry of immunoglobulin gene products

scientific article

Crystallization and preliminary X-ray diffraction analysis of monkey dimeric dihydrodiol dehydrogenase.

scientific article published on 21 December 2001

Dealing with intractable protein cores: protein sequencing of the Mcg IgG and the Yvo IgM heavy chain variable domains

scientific article published on September 2002

Dissimilar aggregation processes govern precipitation and gelation of human IgM cryoglobulins

scientific article published on 01 March 2007

Distinct patterns of diversity, population structure and evolution in the AMA1 genes of sympatric Plasmodium falciparum and Plasmodium vivax populations of Papua New Guinea from an area of similarly high transmission

scientific article

Engineering anti-Lewis-Y hu3S193 antibodies with improved therapeutic ratio for radioimmunotherapy of epithelial cancers

scientific article published on 17 March 2016

Enhanced major histocompatibility complex class I binding and immune responses through anchor modification of the non-canonical tumour-associated mucin 1-8 peptide

scientific article published on November 2006

Exceptionally long CDR3H of bovine scFv antigenized with BoHV-1 B-epitope generates specific immune response against the targeted epitope.

scientific article published on 3 August 2016

Formation of assemblies on cell membranes by secreted proteins: molecular studies of free λ light chain aggregates found on the surface of myeloma cells

scientific article published on September 2013

Free Ig light chains interact with sphingomyelin and are found on the surface of myeloma plasma cells in an aggregated form

scientific article

Global Population Structure of the Genes Encoding the Malaria Vaccine Candidate, Plasmodium vivax Apical Membrane Antigen 1 (PvAMA1).

scientific article

Global conformational changes in IgG-Fc upon mutation of the FcRn-binding site are not associated with altered antibody-dependent effector functions

scientific article published on 05 July 2018

HIV-1 escape from the CCR5 antagonist maraviroc associated with an altered and less-efficient mechanism of gp120-CCR5 engagement that attenuates macrophage tropism

scientific article

Histidine 271 has a functional role in pig alpha-1,3galactosyltransferase enzyme activity.

scientific article

Human antibodies against DBP

scientific article published on 01 September 2019

Identification of a homologue of CD59 in a cyclostome: implications for the evolutionary development of the complement system

scientific article published in January 1999

Identification of preferred carbohydrate binding modes in xenoreactive antibodies by combining conformational filters and binding site maps

scientific article published on 22 February 2010

Identification of residues involved in NS2 homodimerization and elucidation of their impact on the HCV life cycle

scientific article published on 30 August 2011

Improvements, trends, and new ideas in molecular docking: 2012-2013 in review.

scientific article published on 21 March 2015

In silico analysis of antibody-carbohydrate interactions and its application to xenoreactive antibodies

scientific article published on 14 October 2009

Inhibition of destructive autoimmune arthritis in FcgammaRIIa transgenic mice by small chemical entities

scientific article

Insights into the Immunological Properties of Intrinsically Disordered Malaria Proteins Using Proteome Scale Predictions.

scientific article

Interaction of human, rat, and mouse immunoglobulin A (IgA) with Staphylococcal superantigen-like 7 (SSL7) decoy protein and leukocyte IgA receptor

scientific article published on 22 July 2011

Interference of rheumatoid factor activity by aspartame, a dipeptide methyl ester

scientific article published on 01 July 1999

Latest developments in molecular docking: 2010–2011 in review ⬇️

scientific article published on May 1, 2013

Longitudinal Analysis of CCR5 and CXCR4 Usage in a Cohort of Antiretroviral Therapy-Naïve Subjects with Progressive HIV-1 Subtype C Infection.

scientific article

MYB elongation is regulated by the nucleic acid binding of NFκB p50 to the intronic stem-loop region.

scientific article published on 8 April 2015

Macrophage-tropic HIV-1 variants from brain demonstrate alterations in the way gp120 engages both CD4 and CCR5

scientific article

Mannosylation of mutated MBP83-99 peptides diverts immune responses from Th1 to Th2.

scientific article published on 9 June 2008

Mcg light chain dimer as a model system for ligand design: a docking study

article

Modeling of acanthoxin A1, a PLA2 enzyme from the venom of the common death adder (Acanthophis antarcticus)

scientific article published on 01 April 1999

Molecular Docking of Carbohydrate Ligands to Antibodies: Structural Validation against Crystal Structures

scientific article published on 01 December 2009

Molecular Simulations of Carbohydrates with a Fucose-Binding Burkholderia ambifaria Lectin Suggest Modulation by Surface Residues Outside the Fucose-Binding Pocket

scientific article

Molecular properties of human IgG subclasses and their implications for designing therapeutic monoclonal antibodies against infectious diseases

scientific article

Non-canonical anchor motif peptides bound to MHC class I induce cellular responses

article

Non-canonical peptides bound to MHC.

scientific article published on January 2009

Optimization of protein-protein docking for predicting Fc-protein interactions.

scientific article published on 22 July 2016

Peptide inhibitors of xenoreactive antibodies mimic the interaction profile of the native carbohydrate antigens

scientific article published on 01 January 2011

Polymorphisms and interspecies differences of the activating and inhibitory FcγRII of Macaca nemestrina influence the binding of human IgG subclasses

scientific article

Pre-clinical evaluation of a quadrivalent HCV VLP vaccine in pigs following microneedle delivery

scientific article published on 25 June 2019

Probing and pressing surfaces of hepatitis C virus-like particles

scientific article published on 11 March 2019

Proteome-wide mapping of immune features onto Plasmodium protein three-dimensional structures

scientific article

Reactive oxygen species level defines two functionally distinctive stages of inflammatory dendritic cell development from mouse bone marrow

scientific article published on 22 February 2010

Recognition of IgG-Derived Peptides by a Human IgM with an Unusual Combining Site

scientific article published on 01 March 2002

Recombinant shark natural antibodies to thyroglobulin

scientific article

Reply to ‘Response to Milland et al. : Carbohydrate residues downstream of the terminal galα(1,3)gal epitope modulate the specificity of xenoreactive antibodies’

Role for the terminal clasp of HIV-1 gp41 glycoprotein in the initiation of membrane fusion

scientific article published on 5 October 2011

Shear-sensitive nanocapsule drug release for site-specific inhibition of occlusive thrombus formation.

scientific article published on 7 March 2017

Structural Basis for Fc RIIa Recognition of Human IgG and Formation of Inflammatory Signaling Complexes

scientific article

Structural analysis of IgG2A monoclonal antibodies in relation to complement deposition and renal immune complex deposition.

scientific article published in October 2003

Structural aspects of human IgM antibodies expressed in chronic B lymphocytic leukemia

scientific article published in March 1999

Structural basis for antibody targeting of the broadly expressed microbial polysaccharide poly-N-acetyl glucosamine.

scientific article published on 15 February 2018

Structural basis for evasion of IgA immunity by Staphylococcus aureus revealed in the complex of SSL7 with Fc of human IgA1

scientific article

Structural biology of antibody recognition of carbohydrate epitopes and potential uses for targeted cancer immunotherapies

scientific article

Structural convergence of antibody binding of carbohydrate determinants in Lewis Y tumor antigens

scientific article

Structural elements of primary CCR5-using HIV-1 gp120 proteins influencing sensitivity and resistance to the broadly neutralizing monoclonal antibody b12

article

Structural evidence for a new IgG1 antibody sequence allele of cattle

scientific article published on 01 January 2007

Structural patterns of selection and diversity for Plasmodium vivax antigens DBP and AMA1.

scientific article

Structure activity relationship of dendrimer microbicides with dual action antiviral activity

scientific article (publication date: 23 August 2010)

Structure and function relationships in proteins: a tribute to Allen B. Edmundson

scientific article

Structure of human aldose reductase holoenzyme in complex with statil: an approach to structure-based inhibitor design of the enzyme

scientific article

Studies on carbohydrate xenoantigens

scientific article published on January 2012

The N-terminus of EXP2 forms the membrane-associated pore of the protein exporting translocon PTEX in Plasmodium falciparum

scientific article published on 01 March 2019

The acid-labile subunit of the serum insulin-like growth factor-binding protein complexes. Structural determination by molecular modeling and electron microscopy.

scientific article

The carbohydrate-binding promiscuity of Euonymus europaeus lectin is predicted to involve a single binding site.

scientific article published on 10 September 2014

The cationic small molecule GW4869 is cytotoxic to high phosphatidylserine-expressing myeloma cells

scientific article published on 17 February 2017

The membrane effects of melittin on gastric and colorectal cancer

scientific article published on 17 October 2019

The terminal sialic acid of stage-specific embryonic antigen-4 has a crucial role in binding to a cancer-targeting antibody

scientific article published on 12 December 2019

Therapeutic antibodies: Discovery, design and deployment

scientific article published on 16 May 2015

Three-dimensional structure of an immunoglobulin light-chain dimer with amyloidogenic properties

scientific article

Three-dimensional structures of carbohydrate determinants of Lewis system antigens: implications for effective antibody targeting of cancer

scientific article

Three-dimensional structures of idiotypically related Fabs with intermediate and high affinity for fluorescein

scientific article published on June 2004

Two monoclonal antibodies to precisely the same epitope of type II collagen select non-crossreactive phage clones by phage display: implications for autoimmunity and molecular mimicry

scientific article

Virtual Screening Against Carbohydrate-Binding Proteins: Evaluation and Application to Bacterial Burkholderia ambifaria Lectin

scientific article published on 04 September 2018

Virucidal activity of the dendrimer microbicide SPL7013 against HIV-1.

scientific article

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