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List of works by John K Heath

A mass action model of a Fibroblast Growth Factor signaling pathway and its simplification.

scientific article published on 9 October 2008

Biological pathways as communicating computer systems

scientific article published in August 2009

Computational modeling of biological pathways by executable biology

scientific article published in January 2011

Data-dependent electron capture dissociation FT-ICR mass spectrometry for proteomic analyses

scientific article

Database search strategies for proteomic data sets generated by electron capture dissociation mass spectrometry.

scientific article

Determining the LIF-sensitive period for implantation using a LIF-receptor antagonist.

scientific article published on 27 July 2009

DiME: a scalable disease module identification algorithm with application to glioma progression

scientific article

Differential phosphoproteomics of fibroblast growth factor signaling: identification of Src family kinase-mediated phosphorylation events

scientific article published on May 2010

Eps8 controls Src- and FAK-dependent phenotypes in squamous carcinoma cells.

scientific article

FAIMS and Phosphoproteomics of Fibroblast Growth Factor Signaling: Enhanced Identification of Multiply Phosphorylated Peptides

scientific article

FRS2-dependent SRC activation is required for fibroblast growth factor receptor-induced phosphorylation of Sprouty and suppression of ERK activity

scientific article

Fourier transform ion cyclotron resonance mass spectrometry for the analysis of small ubiquitin-like modifier (SUMO) modification: identification of lysines in RanBP2 and SUMO targeted for modification during the E3 autoSUMOylation reaction

scientific article

Functional characterization of W147A: a high-affinity interleukin-11 antagonist

scientific article

Identification and characterization of an inhibitory fibroblast growth factor receptor 2 (FGFR2) molecule, up-regulated in an Apert Syndrome mouse model

scientific article published in May 2011

Identification of sites of ubiquitination in proteins: a fourier transform ion cyclotron resonance mass spectrometry approach

scientific article published in December 2004

LAR protein tyrosine phosphatase regulates focal adhesions through CDK1.

scientific article published on 27 June 2016

Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.

scientific article published on 8 January 2009

Mutations in the immunoglobulin-like domain of gp190, the leukemia inhibitory factor (LIF) receptor, increase or decrease its affinity for LIF.

scientific article published on 24 February 2003

Narrative-based computational modelling of the Gp130/JAK/STAT signalling pathway

scientific article

Nbr1 is a novel inhibitor of ligand-mediated receptor tyrosine kinase degradation

scientific article published on 11 October 2010

Novel binding partners and differentially regulated phosphorylation sites clarify Eps8 as a multi-functional adaptor

scientific article published in 2013

Oncostatin M (OSM) cytostasis of breast tumor cells: characterization of an OSM receptor beta-specific kernel

scientific article published on November 2006

Plakoglobin-dependent regulation of keratinocyte apoptosis by Rnd3.

scientific article

Probing the complementarity of FAIMS and strong cation exchange chromatography in shotgun proteomics

scientific article published on 12 February 2013

Protein partners in the life history of activated fibroblast growth factor receptors

scientific article published in December 2007

Quantifying receptor trafficking and colocalization with confocal microscopy

scientific article published on 25 January 2017

Quantitative Phosphoproteomics Reveals a Role for Collapsin Response Mediator Protein 2 in PDGF-Induced Cell Migration

scientific article

Regulated expression of FLRT genes implies a functional role in the regulation of FGF signalling during mouse development

scientific journal article

Regulation of Platelet Derived Growth Factor Signaling by Leukocyte Common Antigen-related (LAR) Protein Tyrosine Phosphatase: A Quantitative Phosphoproteomics Study

scientific article published on 13 April 2016

Regulation of fibroblast growth factor receptor signalling and trafficking by Src and Eps8

scientific article published on 30 November 2012

Residue-specific immobilization of protein molecules by size-selected clusters

scientific article published in June 2005

RhoJ interacts with the GIT-PIX complex and regulates focal adhesion disassembly

scientific article published on 13 June 2014

SLoMo: automated site localization of modifications from ETD/ECD mass spectra

scientific article published in April 2009

Signal transducers and activators of transcription-3 binding to the fibroblast growth factor receptor is activated by receptor amplification.

scientific article published on 13 April 2010

Skeletal development is regulated by fibroblast growth factor receptor 1 signalling dynamics

scientific article published on 10 December 2003

Src kinase modulates the activation, transport and signalling dynamics of fibroblast growth factor receptors

scientific article published on 2 November 2007

Targeted online liquid chromatography electron capture dissociation mass spectrometry for the localization of sites of in vivo phosphorylation in human Sprouty2.

scientific article

The deleted in brachydactyly B domain of ROR2 is required for receptor activation by recruitment of Src

scientific article published on 26 March 2008

The dynamics of signal triggering in a gp130-receptor complex

scientific article published on April 2007

The non-receptor tyrosine kinase Ack1 regulates the fate of activated EGFR by inducing trafficking to the p62/NBR1 pre-autophagosome

scientific article published on 10 January 2014

The production of interleukin-11 and decidualization are compromised in endometrial stromal cells derived from patients with infertility.

scientific article