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List of works by Giovanna Chiorino

A Novel Prostate Cell Type-Specific Gene Signature to Interrogate Prostate Tumor Differentiation Status and Monitor Therapeutic Response (Running Title: Phenotypic Classification of Prostate Tumors)

scientific article published on 10 January 2020

A novel Nrf2-miR-29-desmocollin-2 axis regulates desmosome function in keratinocytes

scientific article published on 6 October 2014

A promoter-proximal transcript targeted by genetic polymorphism controls E-cadherin silencing in human cancers.

scientific article

A randomized double-blind placebo controlled phase I-II study on clinical and molecular effects of dietary supplements in men with precancerous prostatic lesions. Chemoprevention or "chemopromotion"?

scientific article published on 20 April 2015

A systems biology approach to characterize the regulatory networks leading to trabectedin resistance in an in vitro model of myxoid liposarcoma

scientific article

AKR1C3 is a biomarker and druggable target for oropharyngeal tumors

scientific article published on 19 November 2020

Aberrant expression of the neuronal-specific protein DCDC2 promotes malignant phenotypes and is associated with prostate cancer progression

scientific article published on 25 June 2012

Absence of the K303R estrogen receptor α mutation in breast cancer patients exhibiting different responses to aromatase inhibitor anastrozole neoadjuvant treatment ⬇️

scientific article published on September 17, 2010

Altered molecular pathways in melanocytic lesions.

scientific article published on April 2010

Analysis of gene expression in early-stage ovarian cancer.

scientific article

Association between miR-200c and the survival of patients with stage I epithelial ovarian cancer: a retrospective study of two independent tumour tissue collections.

scientific article published on 21 February 2011

Behavioral choices based on patch selection: a model using aggregation methods.

scientific article published in March 1999

CD38 and ZAP-70 are functionally linked and mark CLL cells with high migratory potential

scientific article published on 15 August 2007

CD38/CD31 interactions activate genetic pathways leading to proliferation and migration in chronic lymphocytic leukemia cells

scientific article

Characterization of a new trabectedin-resistant myxoid liposarcoma cell line that shows collateral sensitivity to methylating agents.

scientific article

Cholangiocarcinoma stem-like subset shapes tumor-initiating niche by educating associated macrophages

scientific article published in September 2016

Class II phosphoinositide 3-kinase C2β regulates a novel signaling pathway involved in breast cancer progression.

scientific article published on 26 February 2016

Comparison of microarray platforms for measuring differential microRNA expression in paired normal/cancer colon tissues.

scientific article

Comprehensive Gene Expression Analysis to Identify Differences and Similarities between Sex- and Stage-Stratified Melanoma Samples

scientific article published on 24 March 2022

Context-dependent miR-204 and miR-211 affect the biological properties of amelanotic and melanotic melanoma cells

scientific article published on April 2017

Cross-analysis of gene and miRNA genome-wide expression profiles in human fibroblasts at different stages of transformation

scientific article published on January 2012

Current understanding of the thrombospondin-1 interactome.

scientific article published on 27 January 2014

Development of a yeast-based system to identify new hBRAFV600E functional interactors

scientific article published on 20 September 2018

Dual tumor suppressing and promoting function of Notch1 signaling in human prostate cancer.

scientific article published on 30 June 2016

ESE3/EHF Controls Epithelial Cell Differentiation and Its Loss Leads to Prostate Tumors with Mesenchymal and Stem-like Features

scientific article published on 13 April 2012

ETS transcription factor ESE1/ELF3 orchestrates a positive feedback loop that constitutively activates NF-κB and drives prostate cancer progression

scientific article published on 16 May 2013

ETS transcription factors control transcription of EZH2 and epigenetic silencing of the tumor suppressor gene Nkx3.1 in prostate cancer

scientific article published in 2010

Eps8 involvement in neuregulin1-ErbB4 mediated migration in the neuronal progenitor cell line ST14A.

scientific article published on 31 January 2011

Establishment and characterization of a human intrahepatic cholangiocarcinoma cell line derived from an Italian patient.

scientific article published on 20 October 2015

Establishment of a patient-derived intrahepatic cholangiocarcinoma xenograft model with KRAS mutation

scientific article published in January 2015

Expression of thrombospondin-1 by tumor cells in patient-derived ovarian carcinoma xenografts.

scientific article published on 15 June 2015

GPR55 signalling promotes proliferation of pancreatic cancer cells and tumour growth in mice, and its inhibition increases effects of gemcitabine

scientific article published on 30 July 2018

Gene and microRNA modulation upon trabectedin treatment in a human intrahepatic cholangiocarcinoma paired patient derived xenograft and cell line.

scientific article published on 24 November 2016

Gene expression profiling and prediction of response to hormonal neoadjuvant treatment with anastrozole in surgically resectable breast cancer

scientific article published on 29 April 2010

Glutathione influences c-Myc-induced apoptosis in M14 human melanoma cells

scientific article published on 10 September 2002

Identification of novel vascular markers through gene expression profiling of tumor-derived endothelium

scientific article

In melanocytic lesions the fraction of BRAFV600E alleles is associated with sun exposure but unrelated to ERK phosphorylation

scientific article published on 11 April 2008

Interpretation of expression-profiling results obtained from different platforms and tissue sources: examples using prostate cancer data.

scientific article

MicroRNA-424 impairs ubiquitination to activate STAT3 and promote prostate tumor progression

scientific article

Molecular characterisation of two human cancer cell lines selected in vitro for their chemotherapeutic drug resistance to ET-743.

scientific article published on January 2005

Multifactorial ERβ and NOTCH1 control of squamous differentiation and cancer.

scientific article published on 17 April 2014

Nicotinamide phosphoribosyltransferase (NAMPT) is over-expressed in melanoma lesions

scientific article

PARP1 expression drives the synergistic antitumor activity of trabectedin and PARP1 inhibitors in sarcoma preclinical models

scientific article

Patient-Derived Ovarian Tumor Xenografts Recapitulate Human Clinicopathology and Genetic Alterations

scientific article published on 10 October 2014

Post-apoptotic tumors are more palatable to dendritic cells and enhance their antigen cross-presentation activity.

scientific article published on 9 October 2008

Preclinical activity of EGFR and MEK1/2 inhibitors in the treatment of biliary tract carcinoma.

scientific article published on 13 July 2016

Reduced expression and tumor suppressor function of the ETS transcription factor ESE-3 in prostate cancer

scientific article published on 26 November 2007

Regulation of aromatase expression in breast cancer treated with anastrozole neoadjuvant therapy.

scientific article published on 24 December 2012

Repurposing of the Antiepileptic Drug Levetiracetam to Restrain Neuroendocrine Prostate Cancer and Inhibit Mast Cell Support to Adenocarcinoma

scientific article published on 02 March 2021

Resistance to platinum-based chemotherapy is associated with epithelial to mesenchymal transition in epithelial ovarian cancer

article

Resveratrol inhibits IL-6-induced ovarian cancer cell migration through epigenetic up-regulation of autophagy

scientific article

SOMAscan Proteomics Identifies Novel Plasma Proteins in Amyotrophic Lateral Sclerosis Patients

scientific article published in 2023

Systematic evaluation of the microRNAome through miR-CATCHv2.0 identifies positive and negative regulators of BRAF-X1 mRNA

scientific article published on 19 April 2019

Targeting EGFR/HER2 pathways enhances the antiproliferative effect of gemcitabine in biliary tract and gallbladder carcinomas

scientific article

Targeting of the adaptor protein Tab2 as a novel approach to revert tamoxifen resistance in breast cancer cells

scientific article published on 16 January 2012

Targeting p63 upregulation abrogates resistance to MAPK inhibitors in melanoma

scientific article published on 14 April 2020

Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect

scientific article

The FoxO3a gene is a key negative target of canonical Notch signalling in the keratinocyte UVB response.

scientific article published on 3 April 2008

The SRA protein UHRF1 promotes epigenetic crosstalks and is involved in prostate cancer progression

scientific article

The epithelial-mesenchymal transition induced by keratinocyte growth conditions is overcome by E6 and E7 from HPV16, but not HPV8 and HPV38: characterization of global transcription profiles.

scientific article published on 26 April 2009

Thrombospondin-1 is part of a Slug-independent motility and metastatic program in cutaneous melanoma, in association with VEGFR-1 and FGF-2.

scientific article published on 13 October 2014

Variability in the timing of G(1)/S transition.

scientific article published in May 2002

Wiring miRNAs to pathways: a topological approach to integrate miRNA and mRNA expression profiles

scientific article

c-Myc phosphorylation is required for cellular response to oxidative stress

scientific article published in February 2006

iASPP is a novel autophagy inhibitor in keratinocytes

scientific article published on 28 April 2014

iASPP/p63 autoregulatory feedback loop is required for the homeostasis of stratified epithelia.

scientific article

lncRNAs as Novel Indicators of Patients' Prognosis in Stage I Epithelial Ovarian Cancer: A Retrospective and Multicentric Study.

scientific article

p63 is an alternative p53 repressor in melanoma that confers chemoresistance and a poor prognosis.

scientific article published on 18 February 2013

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