List of works by Norbert Stefan

(1)H MR spectroscopy of skeletal muscle, liver and bone marrow

scientific article

35th Annual Meeting of the European Association for the Study of Diabetes

article

35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999

article

40 EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004 ⬇️

article

A 60 minute hyperglycemic clamp is sufficient to assess both phases of insulin secretion

scientific article published in June 2000

A candidate type 2 diabetes polymorphism near the HHEX locus affects acute glucose-stimulated insulin release in European populations: results from the EUGENE2 study

scientific article published on 26 November 2007

A common genetic variant in WFS1 determines impaired glucagon-like peptide-1-induced insulin secretion

scientific article

A high-risk phenotype associates with reduced improvement in glycaemia during a lifestyle intervention in prediabetes

scientific article published on 24 September 2015

A new variant in the human Kv1.3 gene is associated with low insulin sensitivity and impaired glucose tolerance

scientific article

A novel functional polymorphism (-336A/G) in the promoter of the partitioning-defective protein-6alpha gene is associated with increased glucose tolerance and lower concentrations of serum non-esterified fatty acids

scientific article (publication date: April 2005)

A novel fusion toxin derived from an EpCAM-specific designed ankyrin repeat protein has potent antitumor activity

scientific article published on 12 November 2010

A novel hyperglycaemic clamp for characterization of islet function in humans: assessment of three different secretagogues, maximal insulin response and reproducibility.

scientific article published in May 2000

A novel insulin sensitivity index particularly suitable to measure insulin sensitivity during gestation.

scientific article

AHSG gene variation is not associated with regional body fat distribution--a magnetic resonance study

scientific article published on 8 April 2009

Acute hyperglycemia causes intracellular formation of CML and activation of ras, p42/44 MAPK, and nuclear factor kappaB in PBMCs

scientific article published in March 2003

Acute stimulation of leptin concentrations in humans during hyperglycemic hyperinsulinemia. Influence of free fatty acids and fasting

scientific article published in January 2001

Adiponectin in youth: response to Bacha et al.

scientific article published in June 2004

Adiponectin is functionally active in human islets but does not affect insulin secretory function or beta-cell lipoapoptosis

scientific article published on 4 October 2005

Adiponectin oligomers and ectopic fat in liver and skeletal muscle in humans

scientific article published on 30 October 2008

Age and gender related effects on adipose tissue compartments of subjects with increased risk for type 2 diabetes: a whole body MRI/MRS study.

scientific article published on 6 July 2005

Age-dependent association of serum prolactin with glycaemia and insulin sensitivity in humans.

scientific article published on 9 July 2013

Allele summation of diabetes risk genes predicts impaired glucose tolerance in female and obese individuals

scientific article

Alpha2-Heremans-Schmid glycoprotein/fetuin-A is associated with insulin resistance and fat accumulation in the liver in humans.

scientific article

An extended fatty liver index to predict non-alcoholic fatty liver disease

scientific article published on 12 January 2017

Animal Trichinella infection in Romania: Geographical heterogeneity for the last 8 years

scientific article published in February 2009

Apelin Serum Levels are not Associated with Early Atherosclerosis or Fat Distribution in Young Subjects with Increased Risk for Type 2 Diabetes

scientific article published on 24 January 2011

Association between the Fatty Liver Index and Risk of Type 2 Diabetes in the EPIC-Potsdam Study

scientific article published on 22 April 2015

Association of AHSG Gene Polymorphisms With Fetuin-A Plasma Levels and Cardiovascular Diseases in the EPIC-Potsdam Study

article

Association of Common Genetic Variation in The FOXO1 Gene with β-Cell Dysfunction, Impaired Glucose Tolerance, And Type 2 Diabetes

scientific article published in February 2009

Association of Fetuin-A Level and Diabetes Risk

scientific article published in The Journal of the American Medical Association

Association of Lower Plasma Fetuin-A Levels With Peripheral Arterial Disease in Type 2 Diabetes: Response to Eraso et al

scientific article published on 29 March 2010

Association of common genetic variants in the MAP4K4 locus with prediabetic traits in humans

scientific article

Association of common genetic variation in the FOXO1 gene with beta-cell dysfunction, impaired glucose tolerance, and type 2 diabetes

scientific article published on 13 January 2009

Association of obesity risk SNPs in PCSK1 with insulin sensitivity and proinsulin conversion

scientific article

Association of serum phosphate levels with glucose tolerance, insulin sensitivity and insulin secretion in non-diabetic subjects

scientific article published on 4 January 2006

Association of the FTO rs9939609 single nucleotide polymorphism with C-reactive protein levels

scientific article published on 23 October 2008

Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion

scientific article published on 14 April 2009

Associations of Erythrocyte Fatty Acids in the De Novo Lipogenesis Pathway with Proxies of Liver Fat Accumulation in the EPIC-Potsdam Study

scientific article published on 18 May 2015

Avoidance of hypoglycemia restores hypoglycemia awareness by increasing beta-adrenergic sensitivity in type 1 diabetes

scientific article published in May 2001

Biocompatibility and bioactivity enhancement of Ce stabilized ZrO(2) doped HA coatings by controlled porosity change of Al(2) O(3) substrates.

scientific article

Body adiposity index, body fat content and incidence of type 2 diabetes

article by Matthias B Schulze et al published 17 February 2012 in Diabetologia

C825T polymorphism of the G protein beta3 subunit is associated with obesity but not with insulin sensitivity

scientific article published in April 2004

Cardiorespiratory Fitness, Adiposity, and Mortality

scientific article published in The Journal of the American Medical Association

Cardiorespiratory fitness determines the reduction in blood pressure and insulin resistance during lifestyle intervention

scientific article published in June 2011

Cardiovascular disease in patients with non-alcoholic fatty liver disease

scientific article

Causes and metabolic consequences of Fatty liver

scientific article published on 21 August 2008

Causes, Characteristics, and Consequences of Metabolically Unhealthy Normal Weight in Humans

scientific article published in August 2017

Central insulin administration improves whole-body insulin sensitivity via hypothalamus and parasympathetic outputs in men.

scientific article published on 15 July 2014

Characterisation of beta-cell dysfunction of impaired glucose tolerance: evidence for impairment of incretin-induced insulin secretion.

scientific article published in July 2000

Characterization of metabolically unhealthy normal-weight individuals: Risk factors and their associations with type 2 diabetes

scientific article published on 26 March 2015

Cholesterol synthesis is associated with hepatic lipid content and dependent on fructose/glucose intake in healthy humans

scientific article published on 29 November 2011

Circulating Fetuin-A and Risk of Type 2 Diabetes: A Mendelian Randomization Analysis

scientific article published on 9 March 2018

Circulating Retinol-Binding Protein-4, Insulin Sensitivity, Insulin Secretion, and Insulin Disposition Index in Obese and Nonobese Subjects: Response to Broch et al

scientific article published on 27 July 2007

Circulating fetuin-A and free fatty acids interact to predict insulin resistance in humans

scientific article published in April 2013

Circulating lysophosphatidylcholines are markers of a metabolically benign nonalcoholic fatty liver

scientific article published on 20 March 2013

Circulating palmitoleate strongly and independently predicts insulin sensitivity in humans

scientific article

Comment on Hedderson et al. Prepregnancy SHBG Concentrations and Risk for Subsequently Developing Gestational Diabetes Mellitus. Diabetes Care 2014;37:1296–1303

scientific article published on 20 November 2014

Common genetic variation in the SERPINF1 locus determines overall adiposity, obesity-related insulin resistance, and circulating leptin levels

scientific article

Common genetic variation in the human FNDC5 locus, encoding the novel muscle-derived 'browning' factor irisin, determines insulin sensitivity

scientific article

Common polymorphisms within the NR4A3 locus, encoding the orphan nuclear receptor Nor-1, are associated with enhanced beta-cell function in non-diabetic subjects

scientific article published on 14 August 2009

Common variation in the sodium/glucose cotransporter 2 gene SLC5A2 does neither affect fasting nor glucose-suppressed plasma glucagon concentrations

scientific article

Correlation of Brown Adipose Tissue with Other Body Fat Compartments and Patient Characteristics: A Retrospective Analysis in a Large Patient Cohort Using PET/CT.

scientific article published on 3 November 2017

DPP4 gene variation affects GLP-1 secretion, insulin secretion, and glucose tolerance in humans with high body adiposity

scientific article published on 27 July 2017

Diabetes und Krebsrisiko

scientific article published on 27 April 2012

Diagnostic value of hemoglobin A1c for type 2 diabetes mellitus in a population at risk

scientific article published on 24 January 2011

Dietary Niacin Intake Predicts the Decrease of Liver Fat Content During a Lifestyle Intervention

scientific article published in Scientific Reports

Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene

scientific article published on 03 August 2009

Dissociation between fatty liver and insulin resistance: the role of adipose triacylglycerol lipase

scientific article published on 16 October 2010

Distribution of subcutaneous fat predicts insulin action in obesity in sex-specific manner

scientific article published on September 2008

Divergent associations of height with cardiometabolic disease and cancer: epidemiology, pathophysiology, and global implications

scientific article published on 27 January 2016

Effect of SGLT2 inhibitors on body composition, fluid status and renin-angiotensin-aldosterone system in type 2 diabetes: a prospective study using bioimpedance spectroscopy

article

Effect of experimental elevation of free fatty acids on insulin secretion and insulin sensitivity in healthy carriers of the Pro12Ala polymorphism of the peroxisome proliferator--activated receptor-gamma2 gene

scientific article

Effect of genotype on success of lifestyle intervention in subjects at risk for type 2 diabetes

scientific article published on 13 December 2006

Effect of the pattern of elevated free fatty acids on insulin sensitivity and insulin secretion in healthy humans

scientific article

Effects of 4-week very-high-fructose/glucose diets on insulin sensitivity, visceral fat and intrahepatic lipids: an exploratory trial

scientific article published on 14 March 2011

Effects of a lifestyle intervention in metabolically benign and malign obesity

scientific article published on 21 December 2010

Effects of resveratrol supplementation on liver fat content in overweight and insulin-resistant subjects: A randomized, double-blind, placebo-controlled clinical trial.

scientific article

Elevated hepatic DPP4 activity promotes insulin resistance and non-alcoholic fatty liver disease

scientific article published on 4 August 2017

Elevated plasma nonesterified fatty acids are associated with deterioration of acute insulin response in IGT but not NGT.

scientific article

Empagliflozin Effectively Lowers Liver Fat Content in Well-Controlled Type 2 Diabetes: A Randomized, Double-Blind, Phase 4, Placebo-Controlled Trial

scientific article published on 20 September 2019

Endogenous glucose production, insulin sensitivity, and insulin secretion in normal glucose-tolerant Pima Indians with low birth weight

scientific article

Endothelial NO-synthase intron 4 polymorphism is associated with disturbed in vivo nitric oxide production in individuals prone to type 2 diabetes

scientific article

Environmental and genetic determinants of fatty liver in humans

scientific article published on 07 May 2010

Epithelial cell adhesion molecule-targeted drug delivery for cancer therapy.

scientific article published on 14 January 2013

Erratum to: A novel insulin sensitivity index particularly suitable to measure insulin sensitivity during gestation

scientific article published on 22 May 2017

Evaluation of fasting state-/oral glucose tolerance test-derived measures of insulin release for the detection of genetically impaired β-cell function

scientific article (publication date: 2 December 2010)

Exaggerated insulin secretion in Pima Indians and African-Americans but higher insulin resistance in Pima Indians compared to African-Americans and Caucasians

scientific article published in October 2004

Expression of adiponectin receptor mRNA in human skeletal muscle cells is related to in vivo parameters of glucose and lipid metabolism

scientific article

Family history of diabetes is associated with higher risk for prediabetes: a multicentre analysis from the German Center for Diabetes Research

scientific article published on 24 August 2013

Fatty liver is independently associated with alterations in circulating HDL2 and HDL3 subfractions

scientific article published on 13 November 2007

Fetuin-A induces cytokine expression and suppresses adiponectin production

scientific article

Fetuin-A influences vascular cell growth and production of proinflammatory and angiogenic proteins by human perivascular fat cells.

scientific article published on 4 February 2014

Fibroblast growth factor 21 is elevated in metabolically unhealthy obesity and affects lipid deposition, adipogenesis, and adipokine secretion of human abdominal subcutaneous adipocytes

scientific article published on May 2015

Follow-up whole-body assessment of adipose tissue compartments during a lifestyle intervention in a large cohort at increased risk for type 2 diabetes

scientific article published on 16 August 2010

Fraction of unsaturated fatty acids in visceral adipose tissue (VAT) is lower in subjects with high total VAT volume - a combined 1 H MRS and volumetric MRI study in male subjects

scientific article

Functional significance of the UCSNP-43 polymorphism in the CAPN10 gene for proinsulin processing and insulin secretion in nondiabetic Germans

scientific article published in September 2001

Gen-Umwelt-Interaktion in Pathogenese und Prävention des Diabetes mellitus Typ 2

scientific article published on 31 May 2007

Gene variants of TCF7L2 influence weight loss and body composition during lifestyle intervention in a population at risk for type 2 diabetes

scientific article

Genetic Predisposition to Abdominal Adiposity and Cardiometabolic Risk

scientific article published in The Journal of the American Medical Association

Genetic Variation in the 11β-hydroxysteroid-dehydrogenase 1 Gene Determines NAFLD and Visceral Obesity

scientific article published on 7 October 2016

Genetic Variations inPPARDandPPARGC1ADetermine Mitochondrial Function and Change in Aerobic Physical Fitness and Insulin Sensitivity during Lifestyle Intervention

scientific article published in May 2007

Genetic determinants of insulin action in polycystic ovary syndrome

scientific article published in May 2005

Genetic determination of body fat distribution and the attributive influence on metabolism

scientific article published on 25 May 2017

Genetic variability of procolipase associates with altered insulin secretion in non-diabetic Caucasians

scientific article

Genetic variation in NR1H4 encoding the bile acid receptor FXR determines fasting glucose and free fatty acid levels in humans

scientific article published on 2 May 2013

Genetic variation in TCF7L2 rs7903146 and history of GDM negatively and independently impact on diabetes-associated metabolic traits

scientific article published on 10 November 2018

Genetic variation within the ANGPTL4 gene is not associated with metabolic traits in white subjects at an increased risk for type 2 diabetes mellitus

scientific article published in May 2008

Genetic variation within the APPL locus is not associated with metabolic or inflammatory traits in a healthy White population

scientific article published in August 2007

Genetic variation within the NR1H2 gene encoding liver X receptor β associates with insulin secretion in subjects at increased risk for type 2 diabetes

scientific article published on 2 November 2010

Genetic variation within the TRPM5 locus associates with prediabetic phenotypes in subjects at increased risk for type 2 diabetes.

scientific article published on 12 April 2011

Global trends in body-mass index

scientific article published in June 2011

Glucose allostasis

scientific article published in April 2003

Glucose tolerance, insulin sensitivity and insulin release in European non-diabetic carriers of a polymorphism upstream of CDKN2A and CDKN2B.

scientific article published on 14 January 2011

Glucose-Raising Polymorphisms in the Human Clock Gene Cryptochrome 2 (CRY2) Affect Hepatic Lipid Content

scientific article published on 4 January 2016

Glucose-raising genetic variants in MADD and ADCY5 impair conversion of proinsulin to insulin

scientific article

Glycemia determines the effect of type 2 diabetes risk genes on insulin secretion ⬇️

scientific article published on 29 August 2010

Granulocyte colony-stimulating factor (G-CSF): A saturated fatty acid-induced myokine with insulin-desensitizing properties in humans

scientific article published on 13 February 2016

Hepatic glucokinase expression is associated with lipogenesis and fatty liver in humans.

scientific article published on 13 April 2011

Hepatic lipid accumulation in healthy subjects: A comparative study using spectral fat-selective MRI and volume-localized1H-MR spectroscopy

scientific article published in 2006

Hepatic lipid composition and stearoyl-coenzyme A desaturase 1 mRNA expression can be estimated from plasma VLDL fatty acid ratios

scientific article published on 22 October 2009

Heterogeneity of the Stearoyl-CoA desaturase-1 (SCD1) gene and metabolic risk factors in the EPIC-Potsdam study

scientific article

High Hepatic SCD1 Activity Is Associated with Low Liver Fat Content in Healthy Subjects under a Lipogenic Diet

scientific article published in December 2012

High Visceral Fat Mass and High Liver Fat Are Associated with Resistance to Lifestyle Intervention*

scientific article published in February 2007

High alanine aminotransferase is associated with decreased hepatic insulin sensitivity and predicts the development of type 2 diabetes

scientific article published in June 2002

High baseline vitamin C levels do not prevent a positive outcome of a lifestyle intervention

scientific article published in September 2009

High cardiorespiratory fitness is an independent predictor of the reduction in liver fat during a lifestyle intervention in non-alcoholic fatty liver disease

scientific article

High cerebral insulin sensitivity is associated with loss of body fat during lifestyle intervention.

scientific article published on 17 September 2011

High circulating retinol-binding protein 4 is associated with elevated liver fat but not with total, subcutaneous, visceral, or intramyocellular fat in humans.

scientific article published on 26 January 2007

High plasma fetuin-A is associated with increased carotid intima-media thickness in a middle-aged population

scientific article published in December 2009

Hypothalamic and Striatal Insulin Action Suppresses Endogenous Glucose Production and May Stimulate Glucose Uptake During Hyperinsulinemia in Lean but Not in Overweight Men.

scientific article published on 7 February 2017

Identification and characterization of metabolically benign obesity in humans

scientific article

Identification of serum metabolites associated with risk of type 2 diabetes using a targeted metabolomic approach

scientific article published on 4 October 2012

Impact of age on the relationships of brown adipose tissue with sex and adiposity in humans

scientific article

Impact of different fat depots on insulin sensitivity: predominant role of liver fat.

scientific article published on September 2007

Impact of diverse chemotherapeutic agents and external factors on activation of brown adipose tissue in a large patient collective

scientific article published in Scientific Reports

Impact of the adipokine adiponectin and the hepatokine fetuin-A on the development of type 2 diabetes: prospective cohort- and cross-sectional phenotyping studies

scientific article

Impact of variation in the FTO gene on whole body fat distribution, ectopic fat, and weight loss

scientific article published on 29 May 2008

Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms

article

Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms

scientific article published on 8 January 2009

Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms.

scientific article

Impairment of GLP1-induced insulin secretion: role of genetic background, insulin resistance and hyperglycaemia

scientific article published on October 2012

In vitro responsiveness of human muscle cell peroxisome proliferator-activated receptor δ reflects donors' insulin sensitivity in vivo

scientific article published on 25 May 2011

Increased fat accumulation in liver may link insulin resistance with subcutaneous abdominal adipocyte enlargement, visceral adiposity, and hypoadiponectinemia in obese individuals

scientific article published in February 2008

Increased insulin clearance in peroxisome proliferator-activated receptor gamma2 Pro12Ala

scientific article

Increasing the antitumor effect of an EpCAM-targeting fusion toxin by facile click PEGylation

scientific article published on November 2013

Individual stearoyl-coa desaturase 1 expression modulates endoplasmic reticulum stress and inflammation in human myotubes and is associated with skeletal muscle lipid storage and insulin sensitivity in vivo

scientific article published on 28 May 2009

Individualisierte Prävention des Typ-2-Diabetes

scientific article published in July 2009

Inhibition of 11β-HSD1 with RO5093151 for non-alcoholic fatty liver disease: a multicentre, randomised, double-blind, placebo-controlled trial

scientific article published on 17 February 2014

Insulin Resistance and Congestive Heart Failure

scientific article published in The Journal of the American Medical Association

Insulin Resistant Phenotype of Polycystic Ovary Syndrome does not Seem to be Caused by Variation in FTO

scientific article published on 30 July 2012

Insulin Sensitivity and Liver Fat: Role of Iron Load

scientific article published in June 2011

Insulin sensitivity, insulin release and glucagon-like peptide-1 levels in persons with impaired fasting glucose and/or impaired glucose tolerance in the EUGENE2 study

scientific article

Interaction effect between common polymorphisms in PPARgamma2 (Pro12Ala) and insulin receptor substrate 1 (Gly972Arg) on insulin sensitivity

scientific article published on 15 September 2001

Intermuscular adipose tissue (IMAT): association with other adipose tissue compartments and insulin sensitivity.

scientific article published in June 2009

Interscapular fat is strongly associated with insulin resistance

scientific article published on 21 July 2010

Intra- and interindividual variability of fatty acid unsaturation in six different human adipose tissue compartments assessed by 1 H-MRS in vivo at 3 T.

scientific article published on 25 May 2017

Intrahepatic lipids are predicted by visceral adipose tissue mass in healthy subjects

scientific article published in November 2004

Leberenzymerhöhung und metabolisches Risiko – Fall 7/2011

scientific article published in July 2011

Leptin down-regulates insulin action through phosphorylation of serine-318 in insulin receptor substrate 1.

scientific article

Letter by Stefan et al regarding article, "Impact of body mass index and the metabolic syndrome on the risk of cardiovascular disease and death in middle-aged men".

scientific article published in September 2010

Lifestyle intervention in individuals with normal versus impaired glucose tolerance

scientific article published on July 2007

Liver fat and insulin resistance are independently associated with the -514C>T polymorphism of the hepatic lipase gene

scientific article published on 26 April 2005

Low hepatic stearoyl-CoA desaturase 1 activity is associated with fatty liver and insulin resistance in obese humans

scientific article

Low plasma adiponectin concentrations do not predict weight gain in humans

scientific article published on October 2002

Measures of adiposity and fat distribution and risk of diabetes

scientific article published in January 2013

Mechanisms Explaining the Relationship Between Metabolically Healthy Obesity and Cardiovascular Risk

scientific article published in June 2014

Metabolic crosstalk between fatty pancreas and fatty liver: effects on local inflammation and insulin secretion

scientific article published on 8 August 2017

Metabolic effects of the Gly1057Asp polymorphism in IRS-2 and interactions with obesity

scientific article published in June 2003

Metabolic signatures of cultured human adipocytes from metabolically healthy versus unhealthy obese individuals

scientific article

Metabolically healthy obesity and cardiovascular events: A systematic review and meta-analysis

scientific article published on 23 December 2015

Metabolically healthy obesity: epidemiology, mechanisms, and clinical implications

scientific article published on 30 August 2013

Metabolically healthy obesity: the low-hanging fruit in obesity treatment?

scientific article published on 14 September 2017

Muscle-derived angiopoietin-like protein 4 is induced by fatty acids via peroxisome proliferator-activated receptor (PPAR)-delta and is of metabolic relevance in humans

scientific article published on 15 December 2008

NS2B/3 proteolysis at the C-prM junction of the tick-borne encephalitis virus polyprotein is highly membrane dependent

scientific article published on 19 June 2012

New imaging techniques of fat, muscle and liver within the context of determining insulin sensitivity

scientific article

Nichtalkoholische Steatohepatitis

scientific article published on 5 March 2011

No association between variation in the NR4A1 gene locus and metabolic traits in white subjects at increased risk for type 2 diabetes

scientific article

Non-alcoholic fatty liver disease and impaired proinsulin conversion as newly identified predictors of the long-term non-response to a lifestyle intervention for diabetes prevention: results from the TULIP study

scientific article published on 24 August 2017

Non-invasive assessment and quantification of liver steatosis by ultrasound, computed tomography and magnetic resonance

scientific article published on 11 June 2009

Nonalcoholic Fatty Liver Disease and Coronary Artery Calcification

scientific article published in September 2016

Nonalcoholic Fatty Liver Disease and Mortality

scientific article published in July 2018

Nonsuppressed Glucagon After Glucose Challenge as a Potential Predictor for Glucose Tolerance

scientific article

Nor-1, a novel incretin-responsive regulator of insulin genes and insulin secretion

scientific article published on 17 June 2013

Novel meta-analysis-derived type 2 diabetes risk loci do not determine prediabetic phenotypes

scientific article

Novel obesity risk loci do not determine distribution of body fat depots: a whole-body MRI/MRS study

scientific article

Novel prodrug-like fusion toxin with protease-sensitive bioorthogonal PEGylation for tumor targeting

scientific article

Obesity and renal disease: not all fat is created equal and not all obesity is harmful to the kidneys

scientific article published on 20 April 2014

PNPLA3 variant I148M is associated with altered hepatic lipid composition in humans

scientific article published on 29 June 2014

PPARGC1A mRNA levels of in vitro differentiated human skeletal muscle cells are negatively associated with the plasma oleate concentrations of the donors

scientific article

Palmitate-induced interleukin-6 expression in human coronary artery endothelial cells

scientific article published in December 2004

Pancreatic fat is negatively associated with insulin secretion in individuals with impaired fasting glucose and/or impaired glucose tolerance: a nuclear magnetic resonance study

scientific article published in March 2010

Parasympathetic blockade attenuates augmented pancreatic polypeptide but not insulin secretion in Pima Indians

scientific article published in March 2004

Pathophysiology-based subphenotyping of individuals at elevated risk for type 2 diabetes

scientific article published on 04 January 2021

Periaortic Adipose Tissue Compared With Peribrachial Adipose Tissue Mass as Markers and Possible Modulators of Cardiometabolic Risk

scientific article published in January 2018

Perivascular fatty tissue at the brachial artery is linked to insulin resistance but not to local endothelial dysfunction

scientific article published on 20 August 2008

Peroxisome proliferator-activated receptor gamma (PPARG) modulates free fatty acid receptor 1 (FFAR1) dependent insulin secretion in humans

scientific article

Phenotypes of prediabetes and stratification of cardiometabolic risk

scientific article published on 13 May 2016

Plasma adiponectin and endogenous glucose production in humans

scientific article published in December 2003

Plasma adiponectin concentration is associated with skeletal muscle insulin receptor tyrosine phosphorylation, and low plasma concentration precedes a decrease in whole-body insulin sensitivity in humans

scientific article published in June 2002

Plasma adiponectin concentrations in children: relationships with obesity and insulinemia.

scientific article published in October 2002

Plasma adiponectin levels are not associated with fat oxidation in humans

scientific article published in October 2002

Plasma concentrations of macrophage migration inhibitory factor are elevated in Pima Indians compared to Caucasians and are associated with insulin resistance.

scientific article

Plasma fetuin-A levels and the risk of type 2 diabetes

scientific article published on 15 July 2008

Plasma fetuin-a levels and the risk of myocardial infarction and ischemic stroke

scientific article published on 24 November 2008

Plasma homocysteine concentrations in young individuals at increased risk of type 2 diabetes are associated with subtle differences in glomerular filtration rate but not with insulin resistance.

scientific article published in June 2006

Polymorphisms in the TCF7L2, CDKAL1 and SLC30A8 genes are associated with impaired proinsulin conversion.

scientific article published on 9 February 2008

Polymorphisms in the gene encoding adiponectin receptor 1 are associated with insulin resistance and high liver fat.

scientific article published on 5 October 2005

Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function

scientific article

Polymorphisms within the novel type 2 diabetes risk locus MTNR1B determine beta-cell function

scientific article published in 2008

Preliminary report: genetic variation within the GPBAR1 gene is not associated with metabolic traits in white subjects at an increased risk for type 2 diabetes mellitus

scientific article published on 28 August 2009

Psychological effects of prevention: do participants of a type 2 diabetes prevention program experience increased mental distress?

scientific article published in January 2009

Quantification of pancreatic lipomatosis and liver steatosis by MRI: comparison of in/opposed-phase and spectral-spatial excitation techniques.

scientific article published in May 2008

Quantitative analysis of adipose tissue in single transverse slices for estimation of volumes of relevant fat tissue compartments: a study in a large cohort of subjects at risk for type 2 diabetes by MRI with comparison to anthropometric data

scientific article

RARRES2, encoding the novel adipokine chemerin, is a genetic determinant of disproportionate regional body fat distribution: a comparative magnetic resonance imaging study

scientific article published in April 2009

Reduced adiponectin serum levels in smokers

scientific article published in April 2005

Reducing visceral adipose tissue mass is essential for improving endothelial function in type 2 diabetes prone individuals

scientific article published on 8 July 2010

Regulation of synovial adipocytokines

scientific article published in February 2004

Relationship of Serum Trimethylamine N-Oxide (TMAO) Levels with early Atherosclerosis in Humans

scientific article published on 27 May 2016

Relationships among age, proinsulin conversion, and beta-cell function in nondiabetic humans

scientific article published in February 2002

Relationships between hepatic stearoyl-CoA desaturase-1 activity and mRNA expression with liver fat content in humans

scientific article

Relationships of body composition and liver fat content with insulin resistance in obesity-matched adolescents and adults

scientific article published on 19 March 2014

Relationships of circulating sex hormone-binding globulin with metabolic traits in humans

scientific article

Reply

scientific article published in December 1999

Role of AMP-activated protein kinase gamma 3 genetic variability in glucose and lipid metabolism in non-diabetic whites

scientific article published on 14 August 2007

SIRT1 genetic variants associate with the metabolic response of Caucasians to a controlled lifestyle intervention--the TULIP Study

scientific article

Selective association of plasma non-esterified fatty acid species with circulating interleukin-8 concentrations in humans

scientific article published on 3 December 2008

Serine/threonine protein kinase 25 antisense oligonucleotide treatment reverses glucose intolerance, insulin resistance, and nonalcoholic fatty liver disease in mice.

scientific article published on 20 November 2017

Serum adiponectin levels predict the effect of short-term dietary interventions on insulin sensitivity in humans

scientific article

Sex Hormone–Binding Globulin and Risk of Type 2 Diabetes

scientific article published on 31 December 2009

Sex-Specific Associations of Testosterone With Metabolic Traits

Single Nucleotide Polymorphisms in the G-Protein Coupled Receptor Kinase 5 (GRK5) Gene are associated with Plasma LDL-Cholesterol Levels in Humans.

scientific article

Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance

scientific article

Solutions for low and high accuracy mass spectrometric data matching: a data-driven annotation strategy in nontargeted metabolomics

scientific article

Stimulatory effect of increased non-esterified fatty acid concentrations on proinsulin processing in healthy humans

scientific article published on 26 October 2000

Structural and Magnetoresistive Properties of Nanometric Films Based on Iron and Chromium Oxides on the Si Substrate.

scientific article

T2* relaxometry in liver, pancreas, and spleen in a healthy cohort of one hundred twenty-nine subjects-correlation with age, gender, and serum ferritin

scientific article

TGF-β Contributes to Impaired Exercise Response by Suppression of Mitochondrial Key Regulators in Skeletal Muscle

scientific article published on 29 June 2016

The -8503 G/A Polymorphism of the Adiponectin Receptor 1 Gene Is Associated With Insulin Sensitivity Dependent on Adiposity

scientific article published on 27 January 2006

The Body Adiposity Index and the Sexual Dimorphism in Body Fat

scholarly article by Matthias B Schulze & Norbert Stefan published September 2011 in Obesity

The CCR2 promoter polymorphism T-960A, but not the serum MCP-1 level, is associated with endothelial function in prediabetic individuals

scientific article

The D299G/T399I Toll-like receptor 4 variant associates with body and liver fat: results from the TULIP and METSIM Studies

scientific article

The DGAT2 gene is a candidate for the dissociation between fatty liver and insulin resistance in humans

scientific article

The ENPP1 K121Q polymorphism determines individual susceptibility to the insulin-sensitising effect of lifestyle intervention

scientific article published on 29 November 2009

The Gln223Arg polymorphism of the leptin receptor in Pima Indians: influence on energy expenditure, physical activity and lipid metabolism

scientific article published on 01 December 2002

The Gly1057Asp polymorphism in IRS-2 interacts with obesity to affect beta cell function

scientific article published on 01 April 2004

The Gly972Arg polymorphism in the insulin receptor substrate-1 gene contributes to the variation in insulin secretion in normal glucose-tolerant humans

scientific article published in April 2001

The Hepatokines Fetuin-A and Fetuin-B are up-regulated in the State of Hepatic Steatosis and may differently impact on Glucose Homeostasis in Humans

scientific article published on 14 November 2017

The L162V polymorphism of the peroxisome proliferator activated receptor alpha gene (PPARA) is not associated with type 2 diabetes, BMI or body fat composition

scientific article published on 25 August 2008

The Pro12Ala polymorphism in PPARG2 increases the effectiveness of primary prevention of cardiovascular disease by a lifestyle intervention

scientific article published on 6 April 2007

The Relationships of Plasma Adiponectin with a Favorable Lipid Profile, Decreased Inflammation, and Less Ectopic Fat Accumulation Depend on Adiposity

scientific article published in October 2006

The association between plasma adiponectin and insulin sensitivity in humans depends on obesity

scientific article

The cancer-associated FGFR4-G388R polymorphism enhances pancreatic insulin secretion and modifies the risk of diabetes

retracted scientific article published on June 2013

The common SLC30A8 Arg325Trp variant is associated with reduced first-phase insulin release in 846 non-diabetic offspring of type 2 diabetes patients--the EUGENE2 study

scientific article published on 7 March 2008

The effect of 6-weeks of aerobic exercise training on serum fetuin-A levels in non-diabetic obese women

scientific article

The impact of genetic variation in the G6PC2 gene on insulin secretion depends on glycemia

scientific article published on 8 September 2010

The impact of insulin resistance on the kidney and vasculature

scientific article

The impact of liver fat vs visceral fat in determining categories of prediabetes

scientific article published on 23 January 2010

The importance of brown adipose tissue

scientific article published on 23 July 2009

The inhibitory effect of recent type 2 diabetes risk loci on insulin secretion is modulated by insulin sensitivity

scientific article published on 3 March 2009

The insulin effect on cerebrocortical theta activity is associated with serum concentrations of saturated nonesterified Fatty acids

scientific article published on 9 October 2009

The metabolically benign and malignant fatty liver

scientific article

The protective effect of human renal sinus fat on glomerular cells is reversed by the hepatokine fetuin-A.

scientific article published on 23 May 2017

The risk allele load accelerates the age-dependent decline in beta cell function

scientific article published on 27 January 2009

The role of hepatokines in metabolism

scientific article published on 22 January 2013

Tipping the inflammatory balance: inflammasome activation distinguishes metabolically unhealthy from healthy obesity

scientific article published in September 2013

Untangling the interplay of genetic and metabolic influences on beta-cell function: Examples of potential therapeutic implications involving TCF7L2 and FFAR1.

scientific article published on 22 January 2014

Upstream transcription factor 1 gene polymorphisms are associated with high antilipolytic insulin sensitivity and show gene-gene interactions.

scientific article

Variance of the SGK1 gene is associated with insulin secretion in different European populations: results from the TUEF, EUGENE2, and METSIM studies

scientific article

Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients--EUGENE2 study

scientific article

Variants in the CD36 Gene Locus Determine Whole-Body Adiposity, but Have No Independent Effect on Insulin Sensitivity

scientific article published on 21 October 2010

Variation in the FTO gene influences food intake but not energy expenditure

scientific article

Variation in the Phosphoinositide 3-Kinase Gamma Gene Affects Plasma HDL-Cholesterol without Modification of Metabolic or Inflammatory Markers

scientific article published on 10 December 2015

Variations inPPARDDetermine the Change in Body Composition during Lifestyle Intervention: A Whole-Body Magnetic Resonance Study

scientific article published in April 2008

Visceral obesity modulates the impact of apolipoprotein C3 gene variants on liver fat content

scientific article published on 9 August 2011

[Liver volume, intrahepatic fat and body weight in the course of a lifestyle interventional study: Analysis with quantitative MR-based methods].

scientific article published in April 2015

[S2k Guideline non-alcoholic fatty liver disease].

scientific article published on 13 July 2015

mRNA concentrations of MIF in subcutaneous abdominal adipose cells are associated with adipocyte size and insulin action

scientific article

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