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List of works by Camilla Krakstad

ARID1A loss is prevalent in endometrial hyperplasia with atypia and low-grade endometrioid carcinomas

scientific article published on 19 October 2012

ATAD2 overexpression links to enrichment of B-MYB-translational signatures and development of aggressive endometrial carcinoma

scientific article

Abolition of stress-induced protein synthesis sensitizes leukemia cells to anthracycline-induced death

scientific article published on 8 January 2008

Addition of IMP3 to L1CAM for discrimination between low- and high-grade endometrial carcinomas: a European Network for Individualised Treatment of Endometrial Cancer collaboration study

scientific article published on 03 May 2019

Androgen receptor as potential therapeutic target in metastatic endometrial cancer

scientific article published on 30 June 2016

Aneuploidy related transcriptional changes in endometrial cancer link low expression of chromosome 15q genes to poor survival

scientific article published on 25 December 2016

Annexin-A2 as predictor biomarker of recurrent disease in endometrial cancer

scientific article published on 29 September 2014

Asparaginase-like protein 1 expression in curettage independently predicts lymph node metastasis in endometrial carcinoma: a multicentre study

scientific article published on 19 August 2018

Asparaginase-like protein 1 is an independent prognostic marker in primary endometrial cancer, and is frequently lost in metastatic lesions

scientific article published on 30 October 2017

Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with risk of clear cell ovarian cancer

scientific article published on 21 June 2016

Blocking 17β-hydroxysteroid dehydrogenase type 1 in endometrial cancer: a potential novel endocrine therapeutic approach

scientific article

Blood Metabolites Associate with Prognosis in Endometrial Cancer

scientific article published on 14 December 2019

Blood steroid levels predict survival in endometrial cancer and reflect tumor estrogen signaling

scientific article published on 06 December 2019

Blood steroids are associated with prognosis and fat distribution in endometrial cancer

scientific article published on 26 October 2018

Ca2+/calmodulin-dependent protein kinase II is required for microcystin-induced apoptosis

scientific article published on 16 November 2001

CaM-kinaseII-dependent commitment to microcystin-induced apoptosis is coupled to cell budding, but not to shrinkage or chromatin hypercondensation

scientific article published on 25 November 2005

Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer

scientific article published on 22 September 2015

Class I Phosphoinositide 3-Kinase /p110α and /p110β Isoforms in Endometrial Cancer

scientific article published in 2018

Clinicopathologic and molecular markers in cervical carcinoma: a prospective cohort study

scientific article published on 06 June 2017

Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk

scientific article published on 19 June 2015

Common Genetic Variation in Circadian Rhythm Genes and Risk of Epithelial Ovarian Cancer (EOC).

scientific article

Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer

scientific article

Consortium analysis of gene and gene-folate interactions in purine and pyrimidine metabolism pathways with ovarian carcinoma risk

scientific article

Cyclic AMP induces IPC leukemia cell apoptosis via CRE-and CDK-dependent Bim transcription

scientific journal article

Development of an Image-Guided Orthotopic Xenograft Mouse Model of Endometrial Cancer with Controllable Estrogen Exposure

article

Endometrial Carcinoma Recurrence Score (ECARS) validates to identify aggressive disease and associates with markers of epithelial-mesenchymal transition and PI3K alterations

scientific article published in July 2014

Endometrial cancer cells exhibit high expression of p110β and its selective inhibition induces variable responses on PI3K signaling, cell survival and proliferation

scientific article published on 16 December 2016

Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer

scientific article published in 2013

Epithelial to mesenchymal transition (EMT) is associated with attenuation of succinate dehydrogenase (SDH) in breast cancer through reduced expression of SDHC.

scientific article published in June 2019

Epithelial-Mesenchymal Transition (EMT) Gene Variants and Epithelial Ovarian Cancer (EOC) Risk

scientific article

Evaluating the ovarian cancer gonadotropin hypothesis: a candidate gene study

scientific article published on 17 December 2014

Expression of L1CAM in curettage or high L1CAM level in preoperative blood samples predicts lymph node metastases and poor outcome in endometrial cancer patients

scientific article

Expression of glucocorticoid receptor is associated with aggressive primary endometrial cancer and increases from primary to metastatic lesions

scientific article published on 16 September 2017

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

scientific article published on April 2013

Genetic overlap between endometriosis and endometrial cancer: evidence from cross-disease genetic correlation and GWAS meta-analyses.

scientific article published on 2 April 2018

Genome-wide association study identifies a possible susceptibility locus for endometrial cancer

scientific article

HER2 expression patterns in paired primary and metastatic endometrial cancer lesions

scientific article published on 23 November 2017

High degree of heterogeneity of PD-L1 and PD-1 from primary to metastatic endometrial cancer

scientific article published on 21 January 2020

High level of HSF1 associates with aggressive endometrial carcinoma and suggests potential for HSP90 inhibitors

scientific article

High mRNA levels of 17β-hydroxysteroid dehydrogenase type 1 correlate with poor prognosis in endometrial cancer.

scientific article published on 03 December 2016

High phospho-Stathmin(Serine38) expression identifies aggressive endometrial cancer and suggests an association with PI3K inhibition.

scientific article published on 28 March 2013

High visceral fat percentage is associated with poor outcome in endometrial cancer

scientific article published on 19 October 2017

High-throughput mutation profiling of primary and metastatic endometrial cancers identifies KRAS, FGFR2 and PIK3CA to be frequently mutated

scientific article

Hormone receptor loss in endometrial carcinoma curettage predicts lymph node metastasis and poor outcome in prospective multicentre trial

scientific article

Hypomethylation of the CTCFL/BORIS promoter and aberrant expression during endometrial cancer progression suggests a role as an Epi-driver gene.

scientific article

Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31.

scientific article published on January 2013

Identification of highly connected and differentially expressed gene subnetworks in metastasizing endometrial cancer

scientific article published in PLoS ONE

Identification of nine new susceptibility loci for endometrial cancer

scientific article published in Nature Communications

Identification of six new susceptibility loci for invasive epithelial ovarian cancer

scientific article published on 12 January 2015

Imaging of Preclinical Endometrial Cancer Models for Monitoring Tumor Progression and Response to Targeted Therapy

scientific article published on 27 November 2019

Impact of body mass index and fat distribution on sex steroid levels in endometrial carcinoma: a retrospective study

scientific article published on 07 June 2019

Increased microvascular permeability in mice lacking Epac1 (Rapgef3).

scientific article published on 20 April 2016

Integrated genomic analysis of the 8q24 amplification in endometrial cancers identifies ATAD2 as essential to MYC-dependent cancers

scientific article

Introduction of aromatic ring-containing substituents in cyclic nucleotides is associated with inhibition of toxin uptake by the hepatocyte transporters OATP 1B1 and 1B3.

scientific article

In vivo MR spectroscopy predicts high tumor grade in endometrial cancer

scientific article published in January 2017

KRAS gene amplification and overexpression but not mutation associates with aggressive and metastatic endometrial cancer

scientific article

L1CAM expression in uterine carcinosarcoma is limited to the epithelial component and may be involved in epithelial-mesenchymal transition

scientific article published on 23 August 2018

Lack of estrogen receptor-α is associated with epithelial-mesenchymal transition and PI3K alterations in endometrial carcinoma

scientific article published on 14 January 2013

Landscape of genomic alterations in cervical carcinomas

scientific article

Loss of ASRGL1 expression is an independent biomarker for disease-specific survival in endometrioid endometrial carcinoma.

scientific article published on 7 April 2015

Loss of GPER identifies new targets for therapy among a subgroup of ERα-positive endometrial cancer patients with poor outcome

scientific article

Loss of progesterone receptor links to high proliferation and increases from primary to metastatic endometrial cancer lesions.

scientific article published on 30 September 2014

Mitochondrial-targeted fatty acid analog induces apoptosis with selective loss of mitochondrial glutathione in promyelocytic leukemia cells

scientific article published in July 2003

Molecular profiling in fresh tissue with high tumor cell content promotes enrichment for aggressive adenocarcinomas in cervix

scientific article published on 22 July 2014

Molecular profiling of circulating tumor cells links plasticity to the metastatic process in endometrial cancer

scientific article

Molecular profiling of endometrial carcinoma precursor, primary and metastatic lesions suggests different targets for treatment in obese compared to non-obese patients

scientific article

Multimodal Imaging of Orthotopic Mouse Model of Endometrial Carcinoma

scientific article published on 7 August 2015

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

scientific article published on April 2013

Network-Based Integration of GWAS and Gene Expression Identifies a HOX-Centric Network Associated with Serous Ovarian Cancer Risk

scientific article

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.

scientific article published in May 2015

Nostocyclopeptide-M1: a potent, nontoxic inhibitor of the hepatocyte drug transporters OATP1B3 and OATP1B1.

scientific article published on 24 January 2011

Off-target effect of the Epac agonist 8-pCPT-2'-O-Me-cAMP on P2Y12 receptors in blood platelets

scientific article published on 12 July 2013

PI3K pathway in gynecologic malignancies

scientific article published on January 2013

PIK3CA Amplification Associates with Aggressive Phenotype but Not Markers of AKT-MTOR Signaling in Endometrial Carcinoma

scientific article published on 15 November 2018

PIK3CA exon9 mutations associate with reduced survival, and are highly concordant between matching primary tumors and metastases in endometrial cancer

scientific article published on 31 August 2017

PTEN loss is a context-dependent outcome determinant in obese and non-obese endometrioid endometrial cancer patients

scientific article

Patient-Derived Xenograft Models for Endometrial Cancer Research

scientific article published on 17 August 2018

Plasma growth differentiation factor-15 is an independent marker for aggressive disease in endometrial cancer

scientific article published in PLoS ONE

Polymorphisms in inflammation pathway genes and endometrial cancer risk

scientific article published on 5 December 2012

Poor outcome in hypoxic endometrial carcinoma is related to vascular density

scientific article published on 23 April 2019

Preoperative imaging markers and PDZ-binding kinase tissue expression predict low-risk disease in endometrial hyperplasias and low grade cancers

scientific article published on 31 July 2017

Preoperative quantitative dynamic contrast-enhanced MRI and diffusion-weighted imaging predict aggressive disease in endometrial cancer

scientific article

Preoperative risk stratification in endometrial cancer (ENDORISK) by a Bayesian network model: A development and validation study

scientific article published on 15 May 2020

Preoperative tumor texture analysis on MRI predicts high-risk disease and reduced survival in endometrial cancer

scientific article published on 13 August 2018

Proteomic profiling of endometrioid endometrial cancer reveals differential expression of hormone receptors and MAPK signaling proteins in obese versus non-obese patients

scientific article published on 31 October 2017

Risk of ovarian cancer and the NF-κB pathway: genetic association with IL1A and TNFSF10

scientific article published on 22 November 2013

Stathmin protein level, a potential predictive marker for taxane treatment response in endometrial cancer

scientific article

Stratification based on high tumour cell content in fresh frozen tissue promotes selection of aggressive endometrial carcinomas

scientific article published on 14 December 2011

Survival signalling and apoptosis resistance in glioblastomas: opportunities for targeted therapeutics

scientific article published on June 2010

Switch in FOXA1 status associates with endometrial cancer progression

scientific article

The cAMP-dependent protein kinase pathway as therapeutic target: possibilities and pitfalls

scientific article published on January 2011

The genomic landscape and evolution of endometrial carcinoma progression and abdominopelvic metastasis

scientific article published on 27 June 2016

The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling

scientific article

Tissue and imaging biomarkers for hypoxia predict poor outcome in endometrial cancer

scientific article published on 13 September 2016

Tumour-microenvironmental blood flow determines a metabolomic signature identifying lysophospholipids and resolvin D as biomarkers in endometrial cancer patients

scientific article published on 20 November 2017

Type of vascular invasion in association with progress of endometrial cancer.

scientific article published on 4 October 2017

Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility

scientific article published in PLoS ONE

cAMP effector mechanisms. Novel twists for an 'old' signaling system

scientific article

cAMP protects neutrophils against TNF-alpha-induced apoptosis by activation of cAMP-dependent protein kinase, independently of exchange protein directly activated by cAMP (Epac).

scientific article

rs495139 in the TYMS-ENOSF1 Region and Risk of Ovarian Carcinoma of Mucinous Histology

scientific article published on 21 August 2018

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