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List of works by Leonie S. Young

ADAM22 as a Prognostic and Therapeutic Drug Target in the Treatment of Endocrine-Resistant Breast Cancer

scientific article published on January 1, 2013

AIB1:ERα transcriptional activity is selectively enhanced in aromatase inhibitor-resistant breast cancer cells

scientific article published on May 2012

Adaptation to AI Therapy in Breast Cancer Can Induce Dynamic Alterations in ER Activity Resulting in Estrogen-Independent Metastatic Tumors

scientific article

An autoradiographic study of regional blood flow distribution in the rat kidney during ureteric obstruction--the role of vasoactive compounds

scientific article published in August 2001

Associations and interactions between Ets-1 and Ets-2 and coregulatory proteins, SRC-1, AIB1, and NCoR in breast cancer

scientific article

COX inhibitors modulate bFGF-induced cell survival in MCF-7 breast cancer cells

scientific article (publication date: March 2004)

Coassociation of estrogen receptor and p160 proteins predicts resistance to endocrine treatment; SRC-1 is an independent predictor of breast cancer recurrence

scientific article published on 10 March 2009

Coregulatory protein-orphan nuclear receptor interactions in the human adrenal cortex

scientific article published on July 2005

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer

scientific article published on October 2013

Cyclooxygenase-2 predicts adverse effects of tamoxifen: a possible mechanism of role for nuclear HER2 in breast cancer patients

scientific article

Cytoprotective effects of nitrates in a cellular model of hydronephrosis

scientific article published in July 2002

Cytosolic phospholipase A2-α expression in breast cancer is associated with EGFR expression and correlates with an adverse prognosis in luminal tumours.

scientific article

Differential production of adrenal steroids by purified cells of the human adrenal cortex is relative rather than absolute

scientific article published in January 2003

Endothelin in unilateral ureteral obstruction: vascular and cellular effects

scientific article published in February 2003

Epigenetic reprogramming of HOXC10 in endocrine-resistant breast cancer

scientific article

Ets-2 and p160 proteins collaborate to regulate c-Myc in endocrine resistant breast cancer

scientific article published on 3 December 2007

Expression of the breast cancer metastasis suppressor gene, BRMS1, in human breast carcinoma: lack of correlation with metastasis to axillary lymph nodes.

scientific article

Genomic interaction between ER and HMGB2 identifies DDX18 as a novel driver of endocrine resistance in breast cancer cells.

scientific article published on 06 October 2014

Global Gene Repression by the Steroid Receptor Coactivator SRC-1 Promotes Oncogenesis

article

Global characterization of the SRC-1 transcriptome identifies ADAM22 as an ER-independent mediator of endocrine-resistant breast cancer

scientific article published on 9 November 2011

Growth factor-dependent regulation of survivin by c-myc in human breast cancer

scientific article published on December 2006

HER-2 positive and p53 negative breast cancers are associated with poor prognosis.

scientific article

HOXC11-SRC-1 regulation of S100beta in cutaneous melanoma: new targets for the kinase inhibitor dasatinib

scientific article published on 7 June 2011

Identification and characterization of nucleolin as a COUP-TFII coactivator of retinoic acid receptor β transcription in breast cancer cells

scientific article published in 2012

Induction of Nitric Oxide Synthase is a Key Determinant of Progression to Pulmonary Injury in Experimental Pancreatitis

article

Interaction of developmental transcription factor HOXC11 with steroid receptor coactivator SRC-1 mediates resistance to endocrine therapy in breast cancer [corrected].

scientific article published on 9 February 2010

Junctional adhesion molecule-A is co-expressed with HER2 in breast tumors and acts as a novel regulator of HER2 protein degradation and signaling.

scientific article

Lapatinib: a competitor or companion to trastuzumab?

scientific article published on 11 September 2009

Mapping molecular subtype specific alterations in breast cancer brain metastases identifies clinically relevant vulnerabilities

scientific article published on 26 January 2022

Metastatic progression with resistance to aromatase inhibitors is driven by the steroid receptor coactivator SRC-1.

scientific article

Methods of renal blood flow measurement

scientific article published on January 1996

Modulation of steroidogenic enzymes by orphan nuclear transcriptional regulation may control diverse production of cortisol and androgens in the human adrenal

scientific article published on May 2004

NCOA1 Directly Targets M-CSF1 Expression to Promote Breast Cancer Metastasis.

scientific article

Patient-Derived Xenografts of Breast Cancer.

scientific article published in January 2017

Prosaposin activates the androgen receptor and potentiates resistance to endocrine treatment in breast cancer

scientific article

RE: RNA Disruption Assay as a Biomarker of Pathological Complete Response in Neoadjuvant Trastuzumab-Treated Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer

scientific article published on 4 July 2016

Raised plasma endostatin levels correlate inversely with breast cancer angiogenesis

scientific article published on 01 January 2004

Regional renal blood flow in normal and disease states.

scientific article published on January 1995

RuvBl2 cooperates with Ets2 to transcriptionally regulate hTERT in colon cancer.

scientific article

S100β as a serum marker in endocrine resistant breast cancer

scientific article

Stratification of radiosensitive brain metastases based on an actionable S100A9/RAGE resistance mechanism

scientific article published on 11 April 2022

Superoxide radical and xanthine oxidoreductase activity in the human heart during cardiac operations

scientific article published in November 1995

Sylvester O’halloran surgical scientific meeting

Tamoxifen-induced ER-alpha-SRC-3 interaction in HER2 positive human breast cancer; a possible mechanism for ER isoform specific recurrence.

scientific article

The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression

scientific article published on 21 July 2008

The LIM domain protein LPP is a coactivator for the ETS domain transcription factor PEA3.

scientific article

The function of steroid receptor coactivator-1 in normal tissues and cancer

scientific article published on 7 March 2012

The role of oestrogen receptor {alpha} in human thyroid cancer: contributions from coregulatory proteins and the tyrosine kinase receptor HER2.

scientific article

Transcriptomic Profiling of Sequential Tumors from Breast Cancer Patients Provides a Global View of Metastatic Expression Changes Following Endocrine Therapy

scientific article published on 3 August 2015

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