List of works - Lamberto Maffei

A rich environmental experience reactivates visual cortex plasticity in aged rats

scientific article published on 4 February 2012

A richness that cures

scientific article

A role for retinal brain-derived neurotrophic factor in ocular dominance plasticity.

scientific article

A sensitive period for environmental regulation of eating behavior and leptin sensitivity

scientific article

Acceleration of visual system development by environmental enrichment.

scientific article published in May 2004

Activation of Rho GTPases triggers structural remodeling and functional plasticity in the adult rat visual cortex

scientific article published on October 2011

Activity-dependent PSA expression regulates inhibitory maturation and onset of critical period plasticity.

scientific article published on 18 November 2007

Acute physiological response of mammalian central neurons to axotomy: ionic regulation and electrical activity

scientific article published on 27 September 2004

Antiepileptic effects of botulinum neurotoxin E.

scientific article

Brain plasticity and disease: a matter of inhibition

scientific article

Brain structural and functional development: genetics and experience

scientific article

Brain-derived neurotrophic factor (BDNF) is required for the enhancement of hippocampal neurogenesis following environmental enrichment

scientific article published on 16 October 2006

Developmental Downregulation of Histone Posttranslational Modifications Regulates Visual Cortical Plasticity

article by Elena Putignano et al published April 2007 in Neuron

Developmental downregulation of histone posttranslational modifications regulates visual cortical plasticity

scientific article published in March 2007

Differential effects of NT-4, NGF and BDNF on development of neurochemical architecture and cell size regulation in rat visual cortex during the critical period

scientific article published in January 2007

Differential effects of cortical neurotrophic factors on development of lateral geniculate nucleus and superior colliculus neurons: anterograde and retrograde actions

scientific article published in February 2003

Dynamic regulation of ERK2 nuclear translocation and mobility in living cells

scientific article published on 14 November 2006

ERK signaling is required for eye-specific retino-geniculate segregation

scientific article

Early IGF-1 primes visual cortex maturation and accelerates developmental switch between NKCC1 and KCC2 chloride transporters in enriched animals

scientific article published on 25 February 2016

Early impoverished environment delays the maturation of cerebral cortex

scientific article

Effects of combined training on neuropsychiatric symptoms and quality of life in patients with cognitive decline

scientific article published on 05 August 2019

Effects of dark rearing on phosphorylation of neurotrophin Trk receptors

scientific article published in November 2002

Effects of neurotrophins on synaptic protein expression in the visual cortex of dark-reared rats.

scientific article published in May 2003

Electrophysiology of the postreceptoral visual pathway in mice.

scientific article

Enrich the environment to empower the brain.

scientific article published on 04 March 2009

Enriched early life experiences reduce adult anxiety-like behavior in rats: a role for insulin-like growth factor 1.

scientific article

Enriched environment and acceleration of visual system development

scientific article published in October 2004

Enriched experience and recovery from amblyopia in adult rats: impact of motor, social and sensory components

scientific article published in June 2012

Environment and brain plasticity: towards an endogenous pharmacotherapy

scientific article published on January 2014

Environmental Enrichment Induces Changes in Long-Term Memory for Social Transmission of Food Preference in Aged Mice through a Mechanism Associated with Epigenetic Processes.

scientific article published on 16 July 2018

Environmental enrichment decreases GABAergic inhibition and improves cognitive abilities, synaptic plasticity, and visual functions in a mouse model of Down syndrome

scientific article published on 23 December 2011

Environmental enrichment delays the onset of memory deficits and reduces neuropathological hallmarks in a mouse model of Alzheimer-like neurodegeneration

scientific article

Environmental enrichment effects on development of retinal ganglion cell dendritic stratification require retinal BDNF.

scientific article

Environmental enrichment in adulthood promotes amblyopia recovery through a reduction of intracortical inhibition.

scientific article

Environmental enrichment modulates cortico-cortical interactions in the mouse.

scientific article

Environmental enrichment potentiates thalamocortical transmission and plasticity in the adult rat visual cortex

scientific article published on November 2010

Environmental enrichment prevents effects of dark-rearing in the rat visual cortex

scientific article published on 15 February 2004

Environmental enrichment promotes fiber sprouting after deafferentation of the superior colliculus in the adult rat brain

scientific article published on 6 January 2009

Environmental enrichment promotes plasticity and visual acuity recovery in adult monocular amblyopic rats

scientific article

Environmental enrichment strengthens corticocortical interactions and reduces amyloid-β oligomers in aged mice

scientific article

Evidence for metaplasticity in the human visual cortex

scientific article published on 27 October 2013

Experience-dependent expression of NPAS4 regulates plasticity in adult visual cortex

scientific article published on 6 June 2012

Experience-dependent reactivation of ocular dominance plasticity in the adult visual cortex

scientific article published on 14 August 2010

Expression of BCL-2 via adeno-associated virus vectors rescues thalamic neurons after visual cortex lesion in the adult rat.

scientific article

Expression of the nerve growth factor receptors TrkA and p75NTR in the visual cortex of the rat: development and regulation by the cholinergic input.

scientific article published in February 2002

Extracellular matrix and visual cortical plasticity: freeing the synapse.

scientific article

Fluoxetine Modulates the Activity of Hypothalamic POMC Neurons via mTOR Signaling

scientific article published on 16 April 2018

Fluoxetine in adulthood normalizes GABA release and rescues hippocampal synaptic plasticity and spatial memory in a mouse model of Down syndrome

scientific article published on 19 November 2013

Fluoxetine treatment promotes functional recovery in a rat model of cervical spinal cord injury.

scientific article

Food restriction enhances visual cortex plasticity in adulthood

scientific article published in Nature Communications

Functional masking of deprived eye responses by callosal input during ocular dominance plasticity.

scientific article published in December 2009

GABAergic inhibition in visual cortical plasticity

scientific article

Gene expression patterns underlying the reinstatement of plasticity in the adult visual system

scientific article published on 26 June 2013

Heterozygous knock-out mice for brain-derived neurotrophic factor show a pathway-specific impairment of long-term potentiation but normal critical period for monocular deprivation.

scientific article published in December 2002

IGF-1 restores visual cortex plasticity in adult life by reducing local GABA levels

scientific article

Insulin-like growth factor 1 (IGF-1) mediates the effects of enriched environment (EE) on visual cortical development.

scientific article published on 30 May 2007

Intranasal administration of nerve growth factor (NGF) rescues recognition memory deficits in AD11 anti-NGF transgenic mice

scientific article

Intranasal delivery of BDNF rescues memory deficits in AD11 mice and reduces brain microgliosis

scientific article published on 16 July 2020

Intraocular delivery of BDNF following visual cortex lesion upregulates cytosolic branched chain aminotransferase (BCATc) in the rat dorsal lateral geniculate nucleus.

scientific article published in July 2004

Lamberto Maffei [interview by David Burr].

scientific article published in February 2009

Leukemia inhibitory factor impairs structural and neurochemical development of rat visual cortex in vivo

scientific article published on 11 January 2017

Massage accelerates brain development and the maturation of visual function

scientific article

Maternal enrichment during pregnancy accelerates retinal development of the fetus

scientific article

Molecular basis of plasticity in the visual cortex.

scientific article

Neurotrophins and plasticity in the visual cortex.

scientific article

New perspectives in amblyopia therapy on adults: a critical role for the excitatory/inhibitory balance

scientific article published in 2011

Noninvasive strategies to optimise brain plasticity: from basic research to clinical perspectives.

scientific article published on 30 December 2013

Olfactory evaluation in Mild Cognitive Impairment: correlation with neurocognitive performance and endothelial function.

scientific article published on 28 March 2017

Patterned vision causes CRE-mediated gene expression in the visual cortex through PKA and ERK.

scientific article published in August 2003

Plasticity in the adult brain: lessons from the visual system

scientific article published on 31 July 2008

Protein synthesis in the visual cortex is needed for ocular dominance plasticity

scientific article published in April 2002

Provision of brain-derived neurotrophic factor via anterograde transport from the eye preserves the physiological responses of axotomized geniculate neurons.

scientific article published in January 2003

Reactivation of ocular dominance plasticity in the adult visual cortex

scientific article published in November 2002

Reduced responsiveness to long-term monocular deprivation of parvalbumin neurons assessed by c-Fos staining in rat visual cortex.

scientific article published on 4 February 2009

Reducing intracortical inhibition in the adult visual cortex promotes ocular dominance plasticity.

scientific article published in January 2010

Serotonin triggers a transient epigenetic mechanism that reinstates adult visual cortex plasticity in rats

scientific article published on 12 December 2010

Setting the pace for retinal development: environmental enrichment acts through insulin-like growth factor 1 and brain-derived neurotrophic factor

scientific article published in September 2009

Structural and functional recovery from early monocular deprivation in adult rats

scholarly article

Synergistic effects of brain-derived neurotrophic factor and chondroitinase ABC on retinal fiber sprouting after denervation of the superior colliculus in adult rats.

scientific article published in August 2003

The anterogradely transported BDNF promotes retinal axon remodeling during eye specific segregation within the LGN

scientific journal article

The antidepressant fluoxetine acts on energy balance and leptin sensitivity via BDNF.

scientific article published on 29 January 2018

The antidepressant fluoxetine restores plasticity in the adult visual cortex

scientific article

The effects of preterm infant massage on brain electrical activity

scientific article published in September 2011

The role of high spatial frequencies in face perception

scientific article published in January 2013

Transient synaptic silencing of developing striate cortex has persistent effects on visual function and plasticity

scientific article

Treatment of neurodevelopmental disorders in adulthood

scientific article

Unilateral Application of Cathodal tDCS Reduces Transcallosal Inhibition and Improves Visual Acuity in Amblyopic Patients.

scientific article published on 29 May 2018

Vascular Function Is Improved After an Environmental Enrichment Program: The Train the Brain-Mind the Vessel Study.

scientific article published on 9 April 2018

Visual cortex is rescued from the effects of dark rearing by overexpression of BDNF ⬇️

scientific article published on September 26, 2003

List of works by Lamberto Maffei

A rich environmental experience reactivates visual cortex plasticity in aged rats

A richness that cures

A role for retinal brain-derived neurotrophic factor in ocular dominance plasticity.

A sensitive period for environmental regulation of eating behavior and leptin sensitivity

Acceleration of visual system development by environmental enrichment.

Activation of Rho GTPases triggers structural remodeling and functional plasticity in the adult rat visual cortex

Activity-dependent PSA expression regulates inhibitory maturation and onset of critical period plasticity.

Acute physiological response of mammalian central neurons to axotomy: ionic regulation and electrical activity

Antiepileptic effects of botulinum neurotoxin E.

Brain plasticity and disease: a matter of inhibition

Brain structural and functional development: genetics and experience

Brain-derived neurotrophic factor (BDNF) is required for the enhancement of hippocampal neurogenesis following environmental enrichment

Developmental Downregulation of Histone Posttranslational Modifications Regulates Visual Cortical Plasticity

Developmental downregulation of histone posttranslational modifications regulates visual cortical plasticity

Differential effects of NT-4, NGF and BDNF on development of neurochemical architecture and cell size regulation in rat visual cortex during the critical period

Differential effects of cortical neurotrophic factors on development of lateral geniculate nucleus and superior colliculus neurons: anterograde and retrograde actions

Dynamic regulation of ERK2 nuclear translocation and mobility in living cells

ERK signaling is required for eye-specific retino-geniculate segregation

Early IGF-1 primes visual cortex maturation and accelerates developmental switch between NKCC1 and KCC2 chloride transporters in enriched animals

Early impoverished environment delays the maturation of cerebral cortex

Effects of combined training on neuropsychiatric symptoms and quality of life in patients with cognitive decline

Effects of dark rearing on phosphorylation of neurotrophin Trk receptors

Effects of neurotrophins on synaptic protein expression in the visual cortex of dark-reared rats.

Electrophysiology of the postreceptoral visual pathway in mice.

Enrich the environment to empower the brain.

Enriched early life experiences reduce adult anxiety-like behavior in rats: a role for insulin-like growth factor 1.

Enriched environment and acceleration of visual system development

Enriched experience and recovery from amblyopia in adult rats: impact of motor, social and sensory components

Environment and brain plasticity: towards an endogenous pharmacotherapy

Environmental Enrichment Induces Changes in Long-Term Memory for Social Transmission of Food Preference in Aged Mice through a Mechanism Associated with Epigenetic Processes.

Environmental enrichment decreases GABAergic inhibition and improves cognitive abilities, synaptic plasticity, and visual functions in a mouse model of Down syndrome

Environmental enrichment delays the onset of memory deficits and reduces neuropathological hallmarks in a mouse model of Alzheimer-like neurodegeneration

Environmental enrichment effects on development of retinal ganglion cell dendritic stratification require retinal BDNF.

Environmental enrichment in adulthood promotes amblyopia recovery through a reduction of intracortical inhibition.

Environmental enrichment modulates cortico-cortical interactions in the mouse.

Environmental enrichment potentiates thalamocortical transmission and plasticity in the adult rat visual cortex

Environmental enrichment prevents effects of dark-rearing in the rat visual cortex

Environmental enrichment promotes fiber sprouting after deafferentation of the superior colliculus in the adult rat brain

Environmental enrichment promotes plasticity and visual acuity recovery in adult monocular amblyopic rats

Environmental enrichment strengthens corticocortical interactions and reduces amyloid-β oligomers in aged mice

Evidence for metaplasticity in the human visual cortex

Experience-dependent expression of NPAS4 regulates plasticity in adult visual cortex

Experience-dependent reactivation of ocular dominance plasticity in the adult visual cortex

Expression of BCL-2 via adeno-associated virus vectors rescues thalamic neurons after visual cortex lesion in the adult rat.

Expression of the nerve growth factor receptors TrkA and p75NTR in the visual cortex of the rat: development and regulation by the cholinergic input.

Extracellular matrix and visual cortical plasticity: freeing the synapse.

Fluoxetine Modulates the Activity of Hypothalamic POMC Neurons via mTOR Signaling

Fluoxetine in adulthood normalizes GABA release and rescues hippocampal synaptic plasticity and spatial memory in a mouse model of Down syndrome

Fluoxetine treatment promotes functional recovery in a rat model of cervical spinal cord injury.

Food restriction enhances visual cortex plasticity in adulthood

Functional masking of deprived eye responses by callosal input during ocular dominance plasticity.

GABAergic inhibition in visual cortical plasticity

Gene expression patterns underlying the reinstatement of plasticity in the adult visual system

Heterozygous knock-out mice for brain-derived neurotrophic factor show a pathway-specific impairment of long-term potentiation but normal critical period for monocular deprivation.

IGF-1 restores visual cortex plasticity in adult life by reducing local GABA levels

Insulin-like growth factor 1 (IGF-1) mediates the effects of enriched environment (EE) on visual cortical development.

Intranasal administration of nerve growth factor (NGF) rescues recognition memory deficits in AD11 anti-NGF transgenic mice

Intranasal delivery of BDNF rescues memory deficits in AD11 mice and reduces brain microgliosis

Intraocular delivery of BDNF following visual cortex lesion upregulates cytosolic branched chain aminotransferase (BCATc) in the rat dorsal lateral geniculate nucleus.

Lamberto Maffei [interview by David Burr].

Leukemia inhibitory factor impairs structural and neurochemical development of rat visual cortex in vivo

Massage accelerates brain development and the maturation of visual function

Maternal enrichment during pregnancy accelerates retinal development of the fetus

Molecular basis of plasticity in the visual cortex.

Neurotrophins and plasticity in the visual cortex.

New perspectives in amblyopia therapy on adults: a critical role for the excitatory/inhibitory balance

Noninvasive strategies to optimise brain plasticity: from basic research to clinical perspectives.

Olfactory evaluation in Mild Cognitive Impairment: correlation with neurocognitive performance and endothelial function.

Patterned vision causes CRE-mediated gene expression in the visual cortex through PKA and ERK.

Plasticity in the adult brain: lessons from the visual system

Protein synthesis in the visual cortex is needed for ocular dominance plasticity

Provision of brain-derived neurotrophic factor via anterograde transport from the eye preserves the physiological responses of axotomized geniculate neurons.

Reactivation of ocular dominance plasticity in the adult visual cortex

Reduced responsiveness to long-term monocular deprivation of parvalbumin neurons assessed by c-Fos staining in rat visual cortex.

Reducing intracortical inhibition in the adult visual cortex promotes ocular dominance plasticity.

Serotonin triggers a transient epigenetic mechanism that reinstates adult visual cortex plasticity in rats

Setting the pace for retinal development: environmental enrichment acts through insulin-like growth factor 1 and brain-derived neurotrophic factor

Structural and functional recovery from early monocular deprivation in adult rats

Synergistic effects of brain-derived neurotrophic factor and chondroitinase ABC on retinal fiber sprouting after denervation of the superior colliculus in adult rats.