List of works - Mario Niepel

A cell cycle phosphoproteome of the yeast centrosome

scientific article published on June 2011

A multi-center study on factors influencing the reproducibility of in vitro drug-response studies

Adaptive informatics for multifactorial and high-content biological data

scientific article

Alternative drug sensitivity metrics improve preclinical cancer pharmacogenomics

scientific article published in June 2017

Analysis of growth factor signaling in genetically diverse breast cancer lines

scientific article

Characterization of Torin2, an ATP-competitive inhibitor of mTOR, ATM, and ATR.

scientific article published on 22 February 2013

Classic and contemporary approaches to modeling biochemical reactions

scientific article

Common and cell-type specific responses to anti-cancer drugs revealed by high throughput transcript profiling.

scientific article published on 30 October 2017

Discovering causal pathways linking genomic events to transcriptional states using Tied Diffusion Through Interacting Events (TieDIE).

scientific article published on 27 August 2013

Discovery of Potent and Selective Covalent Inhibitors of JNK

scientific article published on 27 January 2012

Enabling drug discovery for the PARP protein family through the detection of mono-ADP-ribosylation

scientific article published on 07 May 2019

Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs

scientific article

Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data

scientific article

LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures

scientific article

Mass spectrometry based method to increase throughput for kinome analyses using ATP probes

scientific article published on 22 April 2013

Profiles of Basal and stimulated receptor signaling networks predict drug response in breast cancer lines

scientific article

Quantification of sensitivity and resistance of breast cancer cell lines to anti-cancer drugs using GR metrics

scientific article

Receptor-based mechanism of relative sensing and cell memory in mammalian signaling networks

scientific article published on 21 January 2020

Secondary structure in the 5'-leader or 3'-untranslated region reduces protein yield but does not affect the functional interaction between the 5'-cap and the poly(A) tail

scientific article published on November 1999

Systematic analysis of BRAF(V600E) melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis

scientific article

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations

scientific article published on 24 November 2017

The nuclear basket proteins Mlp1p and Mlp2p are part of a dynamic interactome including Esc1p and the proteasome.

scientific article

List of works by Mario Niepel

A cell cycle phosphoproteome of the yeast centrosome

A multi-center study on factors influencing the reproducibility of in vitro drug-response studies

Adaptive informatics for multifactorial and high-content biological data

Alternative drug sensitivity metrics improve preclinical cancer pharmacogenomics

Analysis of growth factor signaling in genetically diverse breast cancer lines

Characterization of Torin2, an ATP-competitive inhibitor of mTOR, ATM, and ATR.

Classic and contemporary approaches to modeling biochemical reactions

Common and cell-type specific responses to anti-cancer drugs revealed by high throughput transcript profiling.

Discovering causal pathways linking genomic events to transcriptional states using Tied Diffusion Through Interacting Events (TieDIE).

Discovery of Potent and Selective Covalent Inhibitors of JNK

Enabling drug discovery for the PARP protein family through the detection of mono-ADP-ribosylation

Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs

Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data

LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures

Mass spectrometry based method to increase throughput for kinome analyses using ATP probes

Profiles of Basal and stimulated receptor signaling networks predict drug response in breast cancer lines

Quantification of sensitivity and resistance of breast cancer cell lines to anti-cancer drugs using GR metrics

Receptor-based mechanism of relative sensing and cell memory in mammalian signaling networks

Secondary structure in the 5'-leader or 3'-untranslated region reduces protein yield but does not affect the functional interaction between the 5'-cap and the poly(A) tail

Systematic analysis of BRAF(V600E) melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations

The nuclear basket proteins Mlp1p and Mlp2p are part of a dynamic interactome including Esc1p and the proteasome.