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List of works by Åslaug Helland

A Longitudinal Study of the Association between Mammographic Density and Gene Expression in Normal Breast Tissue

scientific article published on 06 January 2019

A multi-omic study reveals BTG2 as a reliable prognostic marker for early-stage non-small cell lung cancer.

scientific article published on 15 April 2018

A new method to assess pulmonary changes using (18)F-fluoro-2-deoxyglucose positron emission tomography for lung cancer patients following radiotherapy

scientific article published on 29 August 2017

A unique set of 6 circulating microRNAs for early detection of non-small cell lung cancer

scientific article published on 14 May 2016

Abstract 1962: Differentially expressed microRNAs in adenocarcinomas of the lung and tumor-adjacent normal lung tissue

Abstract 877: Impact of histology and gender on lung cancer survival: a population based study

Alectinib versus chemotherapy in crizotinib-pretreated anaplastic lymphoma kinase (ALK)-positive non-small-cell lung cancer: results from the phase III ALUR study

scientific article published on 14 April 2018

Allelic imbalance at chromosome region 11q23 in cervical carcinomas

scientific article published on 01 April 1999

An increased risk of cervical intra-epithelial neoplasia grade II-III among human papillomavirus positive patients with theHLA-DQA1*0102-DQB1*0602 haplotype: A population-based case–control study of Norwegian women

scientific article published on 01 March 1998

Antibody combinations for optimized staining of macrophages in human lung tumors

scientific article published on 16 April 2020

Assessment of pulmonary 18F-FDG-PET uptake and cytokine profiles in non-small cell lung cancer patients treated with radiotherapy and erlotinib.

scientific article published on 15 June 2017

Association of N-Glycosylation with Breast Carcinoma and Systemic Features Using High-Resolution Quantitative UPLC

scientific article published on 11 April 2014

Atezolizumab Treatment Beyond Progression in Advanced NSCLC: Results From the Randomized, Phase III OAK Study

scientific article published on 11 September 2018

B4-05: Development of a serum marker panel for early lung cancer detection and treatment response assessment using the proximity-ligation assay (PLA)

article

BRAF-mutations in non-small cell lung cancer

scientific article published on 3 February 2014

Brain metastases with poor vascular function are susceptible to pseudoprogression after stereotactic radiation surgery

scientific article published on 17 May 2018

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.

scientific article

Can human papillomavirus testing and vaccination prevent cervical cancer?

scientific article published in October 2001

Circulating microRNAs associated with prolonged overall survival in lung cancer patients treated with nivolumab

scientific article published on 23 April 2018

Clinical significance of disseminated tumour cells in non-small cell lung cancer

scientific article published on 13 August 2013

Clinicopathological characteristics of 11 NSCLC patients with EGFR-exon 20 mutations

scientific article published in September 2012

Cytokine profiling of tumor interstitial fluid of the breast and its relationship with lymphocyte infiltration and clinicopathological characteristics

scientific article published on 24 October 2016

DNA methylation of LRRC3B: a biomarker for survival of early-stage non-small cell lung cancer patients

journal article published in 2018

DNA methylation signature (SAM40) identifies subgroups of the Luminal A breast cancer samples with distinct survival

scientific article

DQA1 and DQB1 genes in patients with squamous cell carcinoma of the cervix: relationship to human papillomavirus infection and prognosis

article

Dabrafenib plus trametinib in patients with previously untreated BRAFV600E-mutant metastatic non-small-cell lung cancer: an open-label, phase 2 trial.

scientific article published on 8 September 2017

Data-driven analysis of immune infiltrate in a large cohort of breast cancer and its association with disease progression, ER activity, and genomic complexity

scientific article published on 7 July 2017

Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers

scientific article

Detection of disseminated tumor cells in lymph nodes from patients with early stage non-small cell lung cancer

scientific article published on 17 June 2016

Differential DNA methylation analysis of breast cancer reveals the impact of immune signaling in radiation therapy

scientific article

Dose painting by numbers in a standard treatment planning system using inverted dose prescription maps

scientific article published on 27 July 2015

Dosimetric impact of a frame-based strategy in stereotactic radiotherapy of lung tumors

scientific article published on 06 February 2012

Drug treatment of alcohol withdrawal

scientific article published in May 2008

Dynamic respiratory gated (18)FDG-PET of lung tumors - a feasibility study

scientific article published in August 2011

EGFR gene alterations in a Norwegian cohort of lung cancer patients selected for surgery.

scientific article

EGFR mutation testing of lung cancer patients - Experiences from Vestfold Hospital Trust

scientific article published on 27 August 2015

EGLN2 DNA methylation and expression interact with HIF1A to affect survival of early-stage NSCLC

scientific article published on 31 January 2019

EMT network-based feature selection improves prognosis prediction in lung adenocarcinoma

scientific article published in PLoS ONE

Effect of the codon 72 polymorphism (c.215G>C, p.Arg72Pro) in combination with somatic sequence variants in the TP53 gene on survival in patients with advanced ovarian carcinoma

scientific article

Epigenetic modifications in KDM lysine demethylases associate with survival of early-stage NSCLC.

scientific article

Epigenome-wide gene-age interaction analysis reveals reversed effects of PRODH DNA methylation on survival between young and elderly early-stage NSCLC patients

scientific article published on 08 June 2020

Evaluation of Prognostic and Predictive Significance of Circulating MicroRNAs in Ovarian Cancer Patients.

scientific article published on 15 February 2017

Excessive Soft Tissue Reaction after Stereotactic Body Radiation Therapy in a Woman with Four Different Cancer Diagnoses

scientific article published on 26 June 2010

Expression levels of uridine 5'-diphospho-glucuronosyltransferase genes in breast tissue from healthy women are associated with mammographic density

scientific article

Fibroblast growth factor receptor 3 (FGFR3) - analyses of the S249C mutation and protein expression in primary cervical carcinomas.

scientific article published in January 2001

Frequent mutations in chromatin-remodelling genes in pulmonary carcinoids

scientific article

Gene expression profiles of breast biopsies from healthy women identify a group with claudin-low features

scientific article published on November 2011

Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers

scientific article

Genetic alterations of the TP53 gene, p53 protein expression and hpv infection in primary cervical carcinomas

article

Genome-wide DNA methylation analyses in lung adenocarcinomas: Association with EGFR, KRAS and TP53 mutation status, gene expression and prognosis

scientific article published on 6 November 2015

Genome-wide DNA methylation profiles in progression to in situ and invasive carcinoma of the breast with impact on gene transcription and prognosis

scientific article

Germline glutathione S-transferase variants in breast cancer: Relation to diagnosis and cutaneous long-term adverse effects after two fractionation patterns of radiotherapy

scientific article published on 01 March 2007

Glycan gene expression signatures in normal and malignant breast tissue; possible role in diagnosis and progression

scientific article published on 11 December 2009

Glycan-related gene expression signatures in breast cancer subtypes; relation to survival

scientific article published on 14 January 2015

GoIFISH: a system for the quantification of single cell heterogeneity from IFISH images

scientific article

Groundbreaking basic research

scientific article published on 10 December 2018

HLA antigens and cervical carcinoma

scientific article

High levels of genomic aberrations in serous ovarian cancers are associated with better survival

scientific article

High number of kinome-mutations in non-small cell lung cancer is associated with reduced immune response and poor relapse-free survival

scientific article

Human papilloma virus detection and typing in 334 lung cancer patients

scientific article published on 21 January 2014

Hva mener norske onkologer om sin arbeidssituasjon?

scientific article published on 01 March 2010

Identification of microRNAs involved in pathways which characterize the expression subtypes of NSCLC

scientific article published on 22 September 2019

Identification of novel fusion genes in lung cancer using breakpoint assembly of transcriptome sequencing data

scientific article

Immune Cell Composition in Human Non-small Cell Lung Cancer

article

Immunohistochemical analysis of p53 protein overexpression in normal, premalignant, and malignant tissues of the cervix uteri

scientific article published on 01 January 1993

Incidence and Survival of Malignant Pleural Mesothelioma in Norway: A Population-Based Study of 1686 Cases

scientific article published on 01 December 2012

Increase in curative treatment and survival of lung cancer in Norway 2001-2016

scientific article published on 16 July 2019

Increasing Age and Carcinoma Not Otherwise Specified: A 20-Year Population Study of 40,118 Lung Cancer Patients

scientific article published on 01 January 2012

Independent validation of early-stage NSCLC prognostic scores incorporating epigenetic and transcriptional biomarkers with gene-gene interactions and main effects

scientific article published on 27 February 2020

Inference of tumor evolution during chemotherapy by computational modeling and in situ analysis of genetic and phenotypic cellular diversity

scientific article published on 23 January 2014

Integrated molecular profiles of invasive breast tumors and ductal carcinoma in situ (DCIS) reveal differential vascular and interleukin signaling

scientific article published on 9 September 2011

Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors.

scientific article published on 13 March 2018

Intra-tumor heterogeneity defines treatment-resistant HER2+ breast tumors

Intratumor heterogeneity defines treatment-resistant HER2+ breast tumors

scholarly article by Inga H Rye et al published November 2018 in Molecular Oncology

Levels and prognostic impact of circulating markers of inflammation, endothelial activation and extracellular matrix remodelling in patients with lung cancer and chronic obstructive pulmonary disease.

scientific article published on 13 July 2018

Lungekreft hos røykere og aldri-røykere

scientific article published on 01 September 2009

Lungekreft: Forbedret prognose gir kapasitetsutfordringer

scientific article published on 26 March 2020

Lysophosphatidic acid-induced transcriptional profile represents serous epithelial ovarian carcinoma and worsened prognosis

scientific article

Mapping Bone Marrow Response in the Vertebral Column by Positron Emission Tomography Following Radiotherapy and Erlotinib Therapy of Lung Cancer

scientific article published on 01 April 2019

Methylation detection oligonucleotide microarray analysis: a high-resolution method for detection of CpG island methylation

scientific article

Microsatellite instability in cervical and endometrial carcinomas

scientific article published on 01 March 1997

Molecular characterisation of TP53 mutated squamous cell carcinomas of the lung to identify putative targets for therapy

scientific article published on 28 May 2020

Mutation testing for non-small-cell lung cancer

scientific article published in April 2012

Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer

scientific article

Mutations in the TP53 gene and protein expression of p53, MDM 2 and p21/WAF-1 in primary cervical carcinomas with no or low human papillomavirus load

scientific article

N-glycan signatures identified in tumor interstitial fluid and serum of breast cancer patients - association with tumor biology and clinical outcome

scientific article published on 26 April 2018

NSCLC depend upon YAP expression and nuclear localization after acquiring resistance to EGFR inhibitors

scientific article published on March 2017

NUT expression in primary lung tumours

scientific article

Non-small cell lung cancer is characterised by a distinct inflammatory signature in serum compared with chronic obstructive pulmonary disease

scientific article

Novel molecular tumor cell markers in regional lymph nodes and blood samples from patients undergoing surgery for non-small cell lung cancer

scientific article

Osimertinib in T790M-positive and -negative patients with EGFR-mutated advanced non-small cell lung cancer (the TREM-study)

scientific article published on 12 March 2020

Osteopontin is a prognostic biomarker in non-small cell lung cancer

scientific article

PIK3CA mutations as prognostic factor in squamous cell lung carcinoma

scientific article published on 28 November 2016

PIK3CA mutations in advanced ovarian carcinomas

scientific article published in March 2005

Palmar bullous blistering induced by erlotinib.

scientific article

Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking.

scientific article

Papillomaviruses, p53, and cervical cancer

scientific article published on May 30, 1992

PathTracer: High-sensitivity detection of differential pathway activity in tumours

scientific article published on 08 November 2019

Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression

scientific article published on 11 June 2015

Primary cervical carcinomas show 2 common regions of deletion at 3P, 1 within the FHIT gene: evaluation of allelic imbalance at FHIT, RB1 and TP53 in relation to survival

scientific article

Profiling of microRNAs in tumor interstitial fluid of breast tumors - a novel resource to identify biomarkers for prognostic classification and detection of cancer

scientific article

Protein Expression and Prognostic Value of Genes in the erb-b Signaling Pathway in Advanced Ovarian Carcinomas

article

Protein expression and prognostic value of genes in the erb-b signaling pathway in advanced ovarian carcinomas

scientific article published on 01 September 2005

Radiation-induced effects on gene expression: an in vivo study on breast cancer

scientific article

Radiotherapy-related lymphopenia in patients with advanced non-small cell lung cancer receiving palliative radiotherapy

scientific article published on 19 February 2020

Rapid reduction in the incidence of cancer of unknown primary. A population-based study

scientific article published on 4 April 2013

Real-world data on nivolumab treatment of non-small cell lung cancer

scientific article

Responses in the diffusivity and vascular function of the irradiated normal brain are seen up until 18 months following SRS of brain metastases

scientific article published on 01 January 2020

Rituximab efficiently depletes B cells in lung tumors and normal lung tissue

scientific article published on 8 January 2016

SIPA1L3 methylation modifies the benefit of smoking cessation on lung adenocarcinoma survival: an epigenomic-smoking interaction analysis

scientific article published on 17 April 2019

Serum cytokine profiles and metabolic tumor burden in patients with non-small cell lung cancer undergoing palliative thoracic radiation therapy.

scientific article

Serum estradiol levels associated with specific gene expression patterns in normal breast tissue and in breast carcinomas

scientific article

Sex-specific trends in lung cancer incidence and survival: a population study of 40,118 cases

scientific article published on 2 January 2011

Stereotactic body radiation therapy is effective and safe in patients with early-stage non-small cell lung cancer with low performance status and severe comorbidity

scientific article

Stereotaktisk bestråling av columnametastaser

scientific article published on 01 November 2012

Strategies for clinical implementation of TNM-Immunoscore in resected nonsmall-cell lung cancer

scientific article

Stromal CD8+ T-cell Density—A Promising Supplement to TNM Staging in Non–Small Cell Lung Cancer

scientific article published on 13 February 2015

Substantial nation-wide improvement in lung cancer relative survival in Norway from 2000 to 2016

scientific article published on 06 June 2018

Subtype-specific micro-RNA expression signatures in breast cancer progression

scientific article

TP53 Mutation Spectrum in Smokers and Never Smoking Lung Cancer Patients

scientific article published on 11 May 2016

TP53 codon 72 polymorphism and cervical cancer: a pooled analysis of individual data from 49 studies.

scientific article

TP53 gene mutations and protein accumulation in primary vaginal carcinomas

scientific article

TP53 mutations among molecular subtypes of HER2-positive tumors.

scientific article published on 17 June 2005

TP53 mutations and codon 72 genotype--impact on survival among ovarian cancer patients

scientific article published on 01 May 2007

TP53 mutations in early-stage ovarian carcinoma, relation to long-term survival

scientific article published on February 2004

Targeted Disruption of ALK Reveals a Potential Role in Hypogonadotropic Hypogonadism

scientific article

Targeting lung cancer through inhibition of checkpoint kinases

scientific article

The MYCN-HMGA2-CDKN2A pathway in non-small cell lung carcinoma--differences in histological subtypes

scientific article published in January 2015

The immune microenvironment in non-small cell lung cancer is predictive of prognosis after surgery

The immune microenvironment in typical carcinoid lung tumor, a brief report of four cases

scientific article published on 20 May 2020

Tiden teller!

scientific article published on 13 May 2014

Trans-omics biomarker model improves prognostic prediction accuracy for early-stage lung adenocarcinoma

scientific article published on 21 August 2019

Two Distinct Categories of Focal Deletions in Cancer Genomes

scientific article

Unique microRNA-profiles in EGFR-mutated lung adenocarcinomas

scientific article

X chromosome inactivation in cervical cancer patients

scientific article published on 01 October 2003

Years of life lost as a measure of cancer burden on a national level

scientific article

[The selected contagions]

scientific article published on 01 October 2008

p53 polymorphism and cervical cancer

scientific article published in The Lancet

p53 polymorphism and risk of cervical cancer

scientific article published on 01 December 1998

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