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List of works by Stefan Wiemann

"Doublex" fluorescent DNA sequencing: two independent sequences obtained simultaneously in one reaction with internal labeling and unlabeled primers.

scientific article

A microscope-based screening platform for large-scale functional protein analysis in intact cells

scientific article published in November 2003

A novel homozygous ARL13B variant in patients with Joubert syndrome impairs its guanine nucleotide-exchange factor activity.

scientific article published on 15 November 2017

A polymorphism at the 3'-untranslated region of the CLOCK gene is associated with adult attention-deficit hyperactivity disorder

scientific article published in April 2008

Aberrant DNA hypermethylation of SDHC: a novel mechanism of tumor development in Carney triad

scientific article

Abrogating GPT2 in triple negative breast cancer inhibits tumor growth and promotes autophagy

scientific article published on 24 December 2020

Advances in CRISPR-Cas9 genome engineering: lessons learned from RNA interference

scientific article

Alternative pre-mRNA processing regulates cell-type specific expression of the IL4l1 and NUP62 genes

scientific article

An integrative model on the role of DMBT1 in epithelial cancer

article

Assembly of a Parts List of the Human Mitotic Cell Cycle Machinery

article published in 2018

Automated cycle sequencing with Taquenase: protocols for internal labeling, dye primer and "doublex" simultaneous sequencing

scientific article published on August 1, 1997

Automated low-redundancy large-scale DNA sequencing by primer walking

scientific article published on 01 October 1993

Automated production of recombinant human proteins as resource for proteome research

scientific article

Being in the right location at the right time

scientific article

CAFTAN: a tool for fast mapping, and quality assessment of cDNAs.

scientific article published on 25 October 2006

CDNAs for functional genomics and proteomics: the German Consortium

scientific article published on October 2003

Candidate methylation sites associated with endocrine therapy resistance in ER+/HER2- breast cancer

scientific article published on 19 July 2020

Chemokine axes in breast cancer: factors of the tumor microenvironment reshape the CCR7-driven metastatic spread of luminal-A breast tumors

scientific article published on 2 March 2016

Cloning of the C alpha catalytic subunit of the bovine cAMP-dependent protein kinase

scientific article published in November 1992

Co-Inflammatory Roles of TGFβ1 in the Presence of TNFα Drive a Pro-inflammatory Fate in Mesenchymal Stem Cells

scientific article published on 11 May 2017

Combinatorial RNAi for quantitative protein network analysis

scholarly article

Combinatorial targeting of FGF and ErbB receptors blocks growth and metastatic spread of breast cancer models

scientific article published on 23 January 2013

Combined DNA methylation and gene expression profiling in gastrointestinal stromal tumors reveals hypomethylation ofSPP1as an independent prognostic factor

article

Complete DNA sequence of yeast chromosome XI.

scientific article published in June 1994

Construction of a physical map of an autism susceptibility region in 7q32.3-q33.

scientific article published in July 2001

Contact spotting of protein microarrays coupled with spike-in of normalizer protein permits time-resolved analysis of ERBB receptor signaling

scientific article

Coordinated Pulses of mRNA and of Protein Translation or Degradation Produce EGF-Induced Protein Bursts

scientific article published on March 2017

Cutis laxa, exocrine pancreatic insufficiency and altered cellular metabolomics as additional symptoms in a new patient with ATP6AP1-CDG.

scientific article published on 27 January 2018

DMBT1, a new member of the SRCR superfamily, on chromosome 10q25.3-26.1 is deleted in malignant brain tumours

scientific article

DelGEF, an RCC1-related protein encoded by a gene on chromosome 11p14 critical for two forms of hereditary deafness

scientific article

Deleted in Malignant Brain Tumors 1 is a versatile mucin-like molecule likely to play a differential role in digestive tract cancer.

scientific article

Differential response to α-oxoaldehydes in tamoxifen resistant MCF-7 breast cancer cells

scientific article

Dissecting the genomic complexity underlying medulloblastoma

scientific article

Diurnal suppression of EGFR signalling by glucocorticoids and implications for tumour progression and treatment

scientific article

Dynamic deterministic effects propagation networks: learning signalling pathways from longitudinal protein array data

scientific article

Dyskerin localizes to the nucleolus and its mislocalization is unlikely to play a role in the pathogenesis of dyskeratosis congenita

scientific article

EGF induces microRNAs that target suppressors of cell migration: miR-15b targets MTSS1 in breast cancer

scientific article

Efficient low redundancy large-scale DNA sequencing at EMBL.

scientific article

Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma

scientific article

Enhancer hijacking activates oncogenic transcription factor NR4A3 in acinic cell carcinomas of the salivary glands

scientific article published in Nature Communications

Environment-induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children

scientific article published on 24 March 2016

Epidermal growth-factor-induced transcript isoform variation drives mammary cell migration

scientific article

Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone

scientific article published on 28 September 2017

Epigenetic upregulation of lncRNAs at 13q14.3 in leukemia is linked to the In Cis downregulation of a gene cluster that targets NF-kB.

scientific article

Epitopes fused to F-pilin are incorporated into functional recombinant pili.

scientific article

Extending pathways based on gene lists using InterPro domain signatures

scientific article

F-Box and Leucine-Rich Repeat Protein 22 Is a Cardiac-Enriched F-Box Protein That Regulates Sarcomeric Protein Turnover and Is Essential for Maintenance of Contractile Function In Vivo ⬇️

scientific article published on September 12, 2012

Filter-supported preparation of lambda phage DNA.

scientific article

Findings made in gene panel to whole genome sequencing: data, knowledge, ethics - and consequences?

scientific article

Five new microsatellite polymorphisms at the q21 region of human chromosome 21.

scientific article published on January 1995

Frequent downregulation of DMBT1 and galectin-3 in epithelial skin cancer.

scientific article published on June 2003

From ORFeome to biology: a functional genomics pipeline

scientific article

Functional Proteomics of Breast Cancer Metabolism Identifies GLUL as Responder during Hypoxic Adaptation

scientific article published on 18 January 2019

Functional genomics and proteomics approaches to study the ERBB network in cancer

scientific article published on 20 March 2009

Functional profiling: from microarrays via cell-based assays to novel tumor relevant modulators of the cell cycle

scientific article

Gamma-BAR, a novel AP-1-interacting protein involved in post-Golgi trafficking

scientific article

Genetic association of the human corticotropin releasing hormone receptor 1 (CRHR1) with binge drinking and alcohol intake patterns in two independent samples

scientific article published in June 2006

Genetically coupled receptor-ligand pair NKp80-AICL enables autonomous control of human NK cell responses.

scientific article published on 8 August 2013

Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway

Genomic organization of a 225-kb region in Xq28 containing the gene for X-linked myotubular myopathy (MTM1) and a related gene (MTMR1)

scientific article

Genomic rearrangement in NEMO impairs NF-kappaB activation and is a cause of incontinentia pigmenti. The International Incontinentia Pigmenti (IP) Consortium

scientific article (publication date: 25 May 2000)

Global microRNA level regulation of EGFR-driven cell-cycle protein network in breast cancer

scientific article

High-Throughput Profiling of Colorectal Cancer Liver Metastases Reveals Intra- and Inter-Patient Heterogeneity in the EGFR and WNT Pathways Associated with Clinical Outcome

scientific article published on 21 April 2022

High-content microscopy identifies new neurite outgrowth regulators

scientific article

High-content screening microscopy identifies novel proteins with a putative role in secretory membrane traffic

scientific article

High-throughput automated DNA sequencing facility with fluorescent labels at the European Molecular Biology Laboratory

scientific article published on September 1992

High-throughput flow cytometry-based assay to identify apoptosis-inducing proteins

scientific article published on 3 May 2007

High-throughput protein analysis integrating bioinformatics and experimental assays.

scientific article published on 03 February 2004

Homozygous missense mutation in the LMAN2L gene segregates with intellectual disability in a large consanguineous Pakistani family

article

Human Proteinpedia enables sharing of human protein data

scientific article

Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration

scientific article

Identification of SLC20A1 and SLC15A4 among other genes as potential risk factors for combined pituitary hormone deficiency

scientific article published on 26 October 2017

Identification of two highly polymorphic CA-repeats (D21S1224 and D21S1261) on human chromosome 21q22.3.

scientific article published on March 1995

Illuminating the human genome.

scientific article

Impact of clinical exomes in neurodevelopmental and neurometabolic disorders.

scientific article published on 30 June 2017

Improved fluorescent cycle sequencing protocol allows reading nearly 1000 bases

scientific article published on 01 August 1994

Increasing the sensitivity of reverse phase protein arrays by antibody-mediated signal amplification

scientific article published on 22 June 2010

Inferring signalling networks from longitudinal data using sampling based approaches in the R-package 'ddepn'

scientific article

Integrated genome and transcriptome sequencing identifies a noncoding mutation in the genome replication factor DONSON as the cause of microcephaly-micromelia syndrome

scientific article published on 19 June 2017

Integrating Proteomics into Precision Oncology

scientific article published on 19 September 2020

Integrating systems biology with clinical research

scientific article published on July 2008

Integrative annotation of 21,037 human genes validated by full-length cDNA clones

scientific article

Isoform C beta 2, an unusual form of the bovine catalytic subunit of cAMP-dependent protein kinase

scientific article published in March 1991

Isolation of human and mouse HMG2a cDNAs: evidence for an HMG2a-specific 3′ untranslated region ⬇️

scientific article published on October 1, 1997

LIFEdb: a database for functional genomics experiments integrating information from external sources, and serving as a sample tracking system

scientific article

LIMT is a novel metastasis inhibiting lncRNA suppressed by EGF and downregulated in aggressive breast cancer

scientific article published on August 2016

Large-scale identification and characterization of alternative splicing variants of human gene transcripts using 56,419 completely sequenced and manually annotated full-length cDNAs

scientific article

Large-scale protein expression for proteome research

scientific article published in September 2005

Liquid-phase electron microscopy of molecular drug response in breast cancer cells reveals irresponsive cell subpopulations related to lack of HER2 homodimers

scientific article

Live-cell assays to identify regulators of ER-to-Golgi trafficking

scientific article published on 3 January 2012

Localization- and mutation-dependent microRNA (miRNA) expression signatures in gastrointestinal stromal tumours (GISTs), with a cluster of co-expressed miRNAs located at 14q32.31.

scientific article

Long noncoding RNA HOTAIR is upregulated in an aggressive subgroup of gastrointestinal stromal tumors (GIST) and mediates the establishment of gene-specific DNA methylation patterns

scientific article published on 24 September 2018

Long-peptide vaccination with driver gene mutations in p53 and Kras induces cancer mutation-specific effector as well as regulatory T cell responses

article

Metabolic transformations in breast cancer subtypes.

scientific article

MicroRNA-200c represses migration and invasion of breast cancer cells by targeting actin-regulatory proteins FHOD1 and PPM1F.

scientific article published on 5 December 2011

MicroRNA-206 functions as a pleiotropic modulator of cell proliferation, invasion and lymphangiogenesis in pancreatic adenocarcinoma by targeting ANXA2 and KRAS genes

scientific article published on 15 December 2014

MicroRNA-30c-2-3p negatively regulates NF-κB signaling and cell cycle progression through downregulation of TRADD and CCNE1 in breast cancer

scientific article

MicroRNA-31 sensitizes human breast cells to apoptosis by direct targeting of protein kinase C epsilon (PKCepsilon).

scientific article published on 30 January 2013

MicroRNA-519a is a novel oncomir conferring tamoxifen resistance by targeting a network of tumour-suppressor genes in ER+ breast cancer

scientific article

MicroRNA-519a-3p mediates apoptosis resistance in breast cancer cells and their escape from recognition by natural killer cells

scientific article published on 3 August 2017

MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-κB and TGF-β signaling pathways.

scientific article

Modeling ERBB receptor-regulated G1/S transition to find novel targets for de novo trastuzumab resistance

scientific article

Modeling breast cell cycle regulation--overcoming drug resistance

scientific article

Mutation and expression analyses of the ribosomal protein gene RPL10 in an extended German sample of patients with autism spectrum disorder

article

Myomasp/LRRC39, a heart- and muscle-specific protein, is a novel component of the sarcomeric M-band and is involved in stretch sensing

scientific article published on 16 September 2010

Navigator-3, a modulator of cell migration, may act as a suppressor of breast cancer progression

scientific article

Norepinephrine transporter and catecholamine-O-methyltransferase gene variants and attention-deficit/hyperactivity disorder symptoms in adults

scientific article published on 12 November 2007

Nucleotide sequence and analysis of the centromeric region of yeast chromosome IX.

scientific article published on January 1995

On target: A public repository for large-scale RNAi experiments

scientific article published on 02 February 2012

PI3K: A master regulator of brain metastasis-promoting macrophages/microglia

scientific article published on 25 October 2018

PML-associated repressor of transcription (PAROT), a novel KRAB-zinc finger repressor, is regulated through association with PML nuclear bodies

scientific article published on 17 January 2006

Paediatric and adult soft tissue sarcomas with NTRK1 gene fusions: a subset of spindle cell sarcomas unified by a prominent myopericytic/haemangiopericytic pattern

scientific article published on 11 February 2016

Phenotypical and molecular distinctness of sinonasal haemangiopericytoma compared to solitary fibrous tumour of the sinonasal tract

scientific article

Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms

scientific journal article

Primer design for automated DNA sequencing utilizing T7 DNA polymerase and internal labeling with fluorescein-15-dATP.

scientific article published on April 1995

Primer design for large scale sequencing.

scientific article published on June 1998

Promoter of the gene encoding the bovine catalytic subunit of cAMP-dependent protein kinase isoform C beta 2.

scientific article

Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project

scientific article (publication date: August 2008)

Protein microarrays as a discovery tool for studying protein-protein interactions

scientific article

Protein signatures of oxidative stress response in a patient specific cell line model for autism

scientific article published on 10 February 2014

Proteomic profiling of breast cancer metabolism identifies SHMT2 and ASCT2 as prognostic factors

scientific article published on 11 October 2017

Proteomics and Beyond: a report on the 3rd Annual Spring Workshop of the HUPO-PSI 21-23 April 2006, San Francisco, CA, USA.

scientific article published on August 2006

QuantProReloaded: quantitative analysis of microspot immunoassays

scientific article

RNAi-based validation of antibodies for reverse phase protein arrays

scientific article

Rat C alpha catalytic subunit of the cAMP-dependent protein kinase: cDNA sequence and evidence that it is the only isoform expressed in myoblasts

scientific article published in June 1991

Re-activation of cAMP pathway by PDE4D inhibition represents a novel druggable axis for overcoming tamoxifen resistance in ER-positive breast cancer

scientific article published on 31 January 2018

Re-expression of microRNA-375 reverses both tamoxifen resistance and accompanying EMT-like properties in breast cancer

scientific article

Recurrent Somatic PDGFRB Mutations in Sporadic Infantile/Solitary Adult Myofibromas But Not in Angioleiomyomas and Myopericytomas

scientific article published on 21 October 2016

Recurrent mutations within the amino-terminal region of β-catenin are probable key molecular driver events in sinonasal hemangiopericytoma

scientific article published on 4 December 2014

Reduced expression of vacuole membrane protein 1 affects the invasion capacity of tumor cells

scientific article

Reducing "double sequences" in automated DNA sequencing with T7 DNA polymerase and internal labeling

scientific article published on 01 May 1996

Reverse phase protein array based tumor profiling identifies a biomarker signature for risk classification of hormone receptor-positive breast cancer

SMART amplification combined with cDNA size fractionation in order to obtain large full-length clones

scientific article

Separation of up to 1000 bases on a modified A.L.F. DNA sequencer.

scientific article published on December 1993

Sequencing and analysis of 51 kb on the right arm of chromosome XV from Saccharomyces cerevisiae reveals 30 open reading frames

scientific article published on March 1996

Sequential changes of the DMBT1 expression and location in normal lung tissue and lung carcinomas

scientific article published in October 2002

So rare we need to hunt for them: reframing the ethical debate on incidental findings

scientific article published on 30 July 2015

Solitary fibrous tumors/hemangiopericytomas with different variants of the NAB2-STAT6 gene fusion are characterized by specific histomorphology and distinct clinicopathological features

scientific article

Statistical methods and software for the analysis of highthroughput reverse genetic assays using flow cytometry readouts

scientific article published on 17 August 2006

Strong EGFR signaling in cell line models of ERBB2-amplified breast cancer attenuates response towards ERBB2-targeting drugs

scientific article

Synaptojanin 2 is a druggable mediator of metastasis and the gene is overexpressed and amplified in breast cancer

scientific article published on 20 January 2015

Systematic comparison of surface coatings for protein microarrays

scholarly article by Birgit Guilleaume published in December 2005

Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.

scientific article

TGFβ1 regulates HGF-induced cell migration and hepatocyte growth factor receptor MET expression via C-ets-1 and miR-128-3p in basal-like breast cancer

scientific article published on 30 July 2018

Targeting PLK1 overcomes T-DM1 resistance via CDK1-dependent phosphorylation and inactivation of Bcl-2/xL in HER2-positive breast cancer.

scientific article published on 2 February 2018

The 3of5 web application for complex and comprehensive pattern matching in protein sequences

scientific article published on 16 March 2006

The German cDNA network: cDNAs, functional genomics and proteomics

scientific article published on January 2003

The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts

scientific article

The LIFEdb database in 2006

scientific article

The Nucleoporin Nup358/RanBP2 Promotes Nuclear Import in a Cargo- and Transport Receptor-Specific Manner

scientific article published on 21 November 2011

The completion of the Mammalian Gene Collection (MGC).

scientific article published on 18 September 2009

The expression of hematopoietic progenitor cell antigen CD34 is regulated by DNA methylation in a site-dependent manner in gastrointestinal stromal tumours.

scientific article published on 26 July 2017

The first RSBI (ISA-TAB) workshop: "can a simple format work for complex studies?".

scientific article

The full-ORF clone resource of the German cDNA Consortium

scientific article

The highly expressed 5'isomiR of hsa-miR-140-3p contributes to the tumor-suppressive effects of miR-140 by reducing breast cancer proliferation and migration.

scientific article

The protein kinase A catalytic subunit Cbeta2: molecular characterization and distribution of the splice variant

scientific article published on October 2000

The systematic functional characterisation of Xq28 genes prioritises candidate disease genes

scientific article published on 17 February 2006

Three CA/GT repeat polymorphisms from loci D21S414 and D21S1234 on human chromosome 21.

scientific article published on March 1994

Time-Resolved Profiling Reveals ATF3 as a Novel Mediator of Endocrine Resistance in Breast Cancer

scientific article published on 11 October 2020

Time-resolved human kinome RNAi screen identifies a network regulating mitotic-events as early regulators of cell proliferation

scientific article

Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs

article

Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs

scientific article

Two dinucleotide repeat polymorphisms at 21q22.3 (D21S416 and D21S1235).

scientific article

X-linked dyskeratosis congenita is caused by mutations in a highly conserved gene with putative nucleolar functions

scientific article

miRNA-1246 induces pro-inflammatory responses in mesenchymal stem/stromal cells by regulating PKA and PP2A.

scientific article

qCMA: a desktop application for quantitative collective cell migration analysis

scientific article published on 5 October 2012

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