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List of works by Henry Lik-Yuen Chan

A baseline tool for predicting response to peginterferon alfa-2a in HBeAg-positive patients with chronic hepatitis B

scientific article published on 29 June 2018

A longitudinal study on the natural history of serum hepatitis B surface antigen changes in chronic hepatitis B

scientific article published on 01 October 2010

A retrospective study on clinical features and prognostic factors of biopsy-proven primary biliary cirrhosis in Chinese patients

scientific article published on 01 October 2005

A review of the natural history of chronic hepatitis B in the era of transient elastography.

scientific article published on January 2009

Assessment of fibrosis by transient elastography compared with liver biopsy and morphometry in chronic liver diseases.

scientific article published on 5 May 2008

Carboxyl-terminal truncated HBx regulates a distinct microRNA transcription program in hepatocellular carcinoma development

scientific article

Change in treatment paradigm in people who previously injected drugs with chronic hepatitis C in the era of direct-acting antiviral therapy

scientific article published on 18 February 2019

Changing scene in hepatitis B serology interpretation

scientific article

Chronic Hepatitis B: A Treatment Update ⬇️

scientific article published on June 8, 2013

Chronic hepatitis B in Asia—new insights from the past decade ⬇️

scientific article published on January 1, 2011

Chronic kidney disease progression in patients with chronic hepatitis B on tenofovir, entecavir, or no treatment

scientific article published on 20 August 2018

Clinical factors associated with liver stiffness in hepatitis B e antigen-positive chronic hepatitis B patients.

scientific article

Clinical scoring system to predict hepatocellular carcinoma in chronic hepatitis B carriers.

scientific article

Community-based lifestyle modification programme for non-alcoholic fatty liver disease: a randomized controlled trial

scientific article published on 23 April 2013

Cost-effectiveness of the highly effective direct-acting antivirals in the treatment of chronic hepatitis C in Hong Kong

scientific article published on May 2017

Diagnosis of fibrosis and cirrhosis using liver stiffness measurement in nonalcoholic fatty liver disease

scientific article published on 01 February 2010

Diet-Quality Scores and Prevalence of Nonalcoholic Fatty Liver Disease: A Population Study Using Proton-Magnetic Resonance Spectroscopy

scientific article published on 29 September 2015

Disease progression of non-alcoholic fatty liver disease: a prospective study with paired liver biopsies at 3 years

scientific article published on 01 July 2010

Editorial: a baseline tool for predicting response to peginterferon alfa-2a in HBeAg-positive patients-same score, different outcomes. Author's Reply

scientific article published on 01 October 2018

Editorial: increasing burden of nonalcoholic fatty liver disease-a call to action. Authors' reply

scientific article published on 01 June 2020

Efficacy of cap-assisted colonoscopy in comparison with regular colonoscopy: a randomized controlled trial

scientific article published on 01 January 2009

Elevated testosterone increases risk of hepatocellular carcinoma in men with chronic hepatitis B and diabetes mellitus

scientific article published on 28 April 2020

Entecavir treatment in patients with severe acute exacerbation of chronic hepatitis B

scientific article published on 07 September 2010

Epigenetic regulation of hepatocellular carcinoma in non-alcoholic fatty liver disease

scientific article published on 07 September 2013

Evaluation of impact of serial hepatitis B virus DNA levels on development of hepatocellular carcinoma

scientific article published on 22 April 2009

Factors associated with improvement in MELD score after antiviral treatment in patients with chronic hepatitis B

scientific article published on 07 February 2020

Fatty pancreas, insulin resistance, and β-cell function: a population study using fat-water magnetic resonance imaging

scientific article

Four-year Outcomes After Cessation of Tenofovir in Immune-tolerant Chronic Hepatitis B Patients

scientific article

Genetic polymorphisms of adiponectin and tumor necrosis factor-alpha and nonalcoholic fatty liver disease in Chinese people

scientific article published in June 2008

Hepatitis B surface antigen quantification: why and how to use it in 2011 - a core group report

scientific article published on 28 June 2011

Hepatitis B virus genotype C is associated with more severe liver fibrosis than genotype B.

scientific article published on 13 August 2009

Hepatitis B virus genotype C takes a more aggressive disease course than hepatitis B virus genotype B in hepatitis B e antigen-positive patients

scientific article

Hepatitis B virus genotype has no impact on hepatitis B e antigen seroconversion after lamivudine treatment

scientific article

Hepatocellular carcinoma and hepatitis B virus

scientific article

High incidence of mortality and recurrent bleeding in patients with Helicobacter pylori-negative idiopathic bleeding ulcers.

scientific article published on 13 May 2009

High prevalence of colorectal neoplasm in patients with non-alcoholic steatohepatitis.

scientific article published on 21 February 2011

High serum interleukin-6 level predicts future hepatocellular carcinoma development in patients with chronic hepatitis B.

scientific article

Higher estimated net endogenous Acid production may be associated with increased prevalence of nonalcoholic Fatty liver disease in chinese adults in Hong Kong

scientific article published on 23 April 2015

Histological severity and clinical outcomes of nonalcoholic fatty liver disease in nonobese patients

scientific article published on 23 June 2016

Impact of dose and duration of corticosteroid on the risk of hepatitis flare in patients with chronic hepatitis B

scientific article published on 25 September 2018

Improvement in enhanced liver fibrosis score and liver stiffness measurement reflects lower risk of hepatocellular carcinoma

scientific article published on 25 April 2019

Incidence of non-alcoholic fatty liver disease in Hong Kong: a population study with paired proton-magnetic resonance spectroscopy.

scientific article published on 6 September 2014

Incorporating Serum Level of Hepatitis B Surface Antigen or Omitting Level of Hepatitis B Virus DNA Does not Affect Calculation of Risk for Hepatocellular Carcinoma in Patients Without Cirrhosis.

scientific article published on 17 November 2015

Liver injury is independently associated with adverse clinical outcomes in patients with COVID-19

scientific article published on 08 July 2020

Liver stiffness measurement predicts long-term survival and complications in non-alcoholic fatty liver disease

scientific article published on 08 December 2019

Liver stiffness-based optimization of hepatocellular carcinoma risk score in patients with chronic hepatitis B.

scientific article

Long-term follow-up of peginterferon and lamivudine combination treatment in HBeAg-positive chronic hepatitis B.

scientific article published in June 2005

Metabolic and adipokine profile of Chinese patients with nonalcoholic fatty liver disease.

scientific article published on 14 August 2006

Metabolic syndrome increases cardiovascular events but not hepatic events and death in patients with chronic hepatitis B.

scientific article published on 29 September 2016

Modelling NAFLD disease burden in four Asian regions-2019-2030

scientific article published on 04 March 2020

Molecular characterization of the fecal microbiota in patients with nonalcoholic steatohepatitis--a longitudinal study

scientific article

Molecular virology in chronic hepatitis B: genotypes

scientific article

Occult HBV infection in cryptogenic liver cirrhosis in an area with high prevalence of HBV infection

scientific article published on 01 May 2002

Outcome of lamivudine resistant hepatitis B virus mutant post-liver transplantation on lamivudine monoprophylaxis.

scientific article

Pathogenesis and novel treatment options for non-alcoholic steatohepatitis

scientific article published on 10 August 2016

Phylogenetic, virological, and clinical characteristics of genotype C hepatitis B virus with TCC at codon 15 of the precore region.

scientific article published on March 2006

Prevention of hepatocellular carcinoma: a concise review of contemporary issues

scientific article published on May 1, 2012

Quantifying and monitoring fibrosis in non-alcoholic fatty liver disease using dual-photon microscopy

scientific article published on 28 September 2019

Quantitative elastography of liver fibrosis and spleen stiffness in chronic hepatitis B carriers: comparison of shear-wave elastography and transient elastography with liver biopsy correlation.

scientific article

Rate and Factors Affecting Treatment Uptake of Patients with Chronic Hepatitis C in a Tertiary Referral Hospital ⬇️

scientific article published on 07 October 2010

Real-life efficacy and safety of paritaprevir/ritonavir, ombitasvir, and dasabuvir in chronic hepatitis C patients in Hong Kong

scientific article published on 21 November 2016

Reimbursement policies in the Asia-Pacific for chronic hepatitis B.

scientific article published on 11 December 2014

Repeating measurements by transient elastography in non-alcoholic fatty liver disease patients with high liver stiffness

scientific article published on 27 June 2018

Responses are durable for up to 5 years after completion of peginterferon alfa-2a treatment in hepatitis B e antigen-positive patients.

scientific article published on 9 March 2018

Review article: long-term safety of oral anti-viral treatment for chronic hepatitis B.

scientific article published on 22 January 2018

Risk estimation for hepatocellular carcinoma in chronic hepatitis B (REACH-B): development and validation of a predictive score.

scientific article published on 14 April 2011

Risk of hepatocellular carcinoma in chronic hepatitis B: assessment and modification with current antiviral therapy.

scientific article

Serum hepatitis B core-related antigen predicts hepatocellular carcinoma in hepatitis B e antigen-negative patients

scientific article published on 17 June 2020

Serum hepatitis B surface antigen quantitation can reflect hepatitis B virus in the liver and predict treatment response.

scientific article published in December 2007

Severe acute exacerbation of chronic hepatitis B: a unique presentation of a common disease

scientific article

Similarly low risk of hepatocellular carcinoma after either spontaneous or nucleos(t)ide analogue-induced hepatitis B surface antigen loss

scientific article published on 22 November 2020

Soluble CD163 and mannose receptor associate with chronic hepatitis B activity and fibrosis and decline with treatment.

scientific article published on 15 June 2017

Statins reduce the risk of liver decompensation and death in chronic viral hepatitis: a propensity score weighted landmark analysis.

scientific article published on 21 September 2017

Surveillance programme for hepatocellular carcinoma improves the survival of patients with chronic viral hepatitis.

scientific article published on 26 September 2007

Switching to peginterferon for chronic hepatitis B patients with hepatitis B e antigen seroconversion on entecavir - A prospective study

scientific article published on 18 October 2018

Tenofovir disoproxil fumarate reduces hepatocellular carcinoma, decompensation and death in chronic hepatitis B patients with cirrhosis

scientific article published on 16 September 2019

The Asia-Pacific Working Party on Nonalcoholic Fatty Liver Disease Guidelines 2017 Part 1: Definition, risk factors and assessment

scientific article published on 3 July 2017

The Effect of Interferon-Free Regimens on Health-Related Quality of Life in East Asian Patients with Chronic Hepatitis C.

scientific article published on 2 December 2017

The G1613A mutation in the HBV genome affects HBeAg expression and viral replication through altered core promoter activity

scientific article

The impact of diabetes mellitus and hepatitis B virus co-infection on patients with chronic hepatitis C - a territory-wide cohort study.

scientific article published on 26 September 2017

The molecular diagnosis of hepatitis B virus-associated hepatocellular carcinoma.

scientific article

The role of quantitative hepatitis B surface antigen revisited.

scientific article

Transient elastography

scientific article

Treatment cessation of entecavir in Asian patients with hepatitis B e antigen negative chronic hepatitis B: a multicentre prospective study

article

Use of Hepatitis B Virus Core Related Antigen to Evaluate Natural History of Chronic Hepatitis B

scientific article published on 15 April 2020

Use of hepatitis B virus DNA quantitation to predict hepatitis B e antigen reversion in cases of chronic hepatitis B.

scientific article

Validation of the NAFLD fibrosis score in a Chinese population with low prevalence of advanced fibrosis.

scientific article published on 4 July 2008

Very low probability of significant liver inflammation in chronic hepatitis B patients with low ALT levels in the absence of liver fibrosis

scientific article published on 04 September 2020

Virus and Host Testing to Manage Chronic Hepatitis B.

scientific article published on June 2016

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