List of works by Brigitte Gicquel

'Z(S)-MDR-TB' versus 'Z(R)-MDR-TB': improving treatment of MDR-TB by identifying pyrazinamide susceptibility

scientific article published on 25 July 2012

A common mechanism of inhibition of the Mycobacterium tuberculosis mycolic acid biosynthetic pathway by isoxyl and thiacetazone

scientific article

A first assessment of the genetic diversity of Mycobacterium tuberculosis complex in Cambodia

scientific article

A genomic portrait of the genetic architecture and regulatory impact of microRNA expression in response to infection

scientific article

A murine DC-SIGN homologue contributes to early host defense against Mycobacterium tuberculosis

scientific journal article

A non-sense mutation in the putative anti-mutator gene ada/alkA of Mycobacterium tuberculosis and M. bovis isolates suggests convergent evolution

scientific article

A point mutation in the two-component regulator PhoP-PhoR accounts for the absence of polyketide-derived acyltrehaloses but not that of phthiocerol dimycocerosates in Mycobacterium tuberculosis H37Ra

scientific article

Activation of type III interferon genes by pathogenic bacteria in infected epithelial cells and mouse placenta

scientific article

AftD, a novel essential arabinofuranosyltransferase from mycobacteria

scientific article published on 04 August 2009

After the bottleneck: Genome-wide diversification of the Mycobacterium tuberculosis complex by mutation, recombination, and natural selection

scientific article published on 29 February 2012

An interferon-related signature in the transcriptional core response of human macrophages to Mycobacterium tuberculosis infection

scientific article

An oligopeptide transporter of Mycobacterium tuberculosis regulates cytokine release and apoptosis of infected macrophages

scientific journal article

Application of sensitive and specific molecular methods to uncover global dissemination of the major RDRio Sublineage of the Latin American-Mediterranean Mycobacterium tuberculosis spoligotype family

scientific article published on 30 January 2008

Bacterial infection remodels the DNA methylation landscape of human dendritic cells

scientific article

Biomarkers for risk of developing active tuberculosis in contacts of TB patients: a prospective cohort study

scientific article

Biosynthesis of mycobacterial lipoarabinomannan: role of a branching mannosyltransferase

scientific journal article

Biosynthetic origin of the galactosamine substituent of Arabinogalactan in Mycobacterium tuberculosis

scientific journal article

Capsular glucan and intracellular glycogen of Mycobacterium tuberculosis: biosynthesis and impact on the persistence in mice

scientific journal article

Combination of single nucleotide polymorphism and variable-number tandem repeats for genotyping a homogenous population of Mycobacterium tuberculosis Beijing strains in China

scientific article published on 11 January 2012

Comparative investigation of the pathogenicity of three Mycobacterium tuberculosis mutants defective in the synthesis of p-hydroxybenzoic acid derivatives

scientific article

Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP

scientific journal article

DC-SIGN induction in alveolar macrophages defines privileged target host cells for mycobacteria in patients with tuberculosis

scientific article

DC-SIGN interacts with Mycobacterium leprae but sequence variation in this lectin is not associated with leprosy in the Pakistani population

scientific article published in January 2006

DC-SIGN is the major Mycobacterium tuberculosis receptor on human dendritic cells

scientific article

DNA repair in Mycobacterium tuberculosis revisited

scientific article published on May 2009

Deciphering the ancient and complex evolutionary history of human arylamine N-acetyltransferase genes

scientific article

Deciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosis infection

scientific article published on 10 January 2012

Deciphering the molecular bases of Mycobacterium tuberculosis binding to the lectin DC-SIGN reveals an underestimated complexity

scientific article published on December 2005

Deciphering the role of IS6110 in a highly transmissible Mycobacterium tuberculosis Beijing strain, GC1237.

scientific article

Definition of the first mannosylation step in phosphatidylinositol mannoside synthesis. PimA is essential for growth of mycobacteria

scientific journal article

Disruption of the gene homologous to mammalian Nramp1 in Mycobacterium tuberculosis does not affect virulence in mice

scientific article

Ecto-5'-Nucleotidase (CD73) Deficiency in Mycobacterium tuberculosis-Infected Mice Enhances Neutrophil Recruitment

scientific article

Effects of omega-3 and -6 fatty acids on Mycobacterium tuberculosis in macrophages and in mice

scientific article published on 14 August 2008

Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis

scientific article published on 20 January 2005

Evidence for a partial redundancy of the fibronectin-binding proteins for the transfer of mycoloyl residues onto the cell wall arabinogalactan termini of Mycobacterium tuberculosis

scientific article

Evolution and diversity of clonal bacteria: the paradigm of Mycobacterium tuberculosis

scientific article

Evolutionary dynamics of human Toll-like receptors and their different contributions to host defense

scientific article

Experimental infection of New Zealand Merino sheep with a suspension of Mycobacterium avium subspecies paratuberculosis (Map) strain Telford: Kinetics of the immune response, histopathology and Map culture

scientific article

Expression of TNF-alpha-dependent apoptosis-related genes in the peripheral blood of Malagasy subjects with tuberculosis

scientific article

Extrapulmonary and pulmonary tuberculosis in antananarivo (madagascar): high clustering rate in female patients

scientific article

Fine-needle aspiration for diagnosis of tuberculous lymphadenitis in children in Bangui, Central African Republic

scientific article published on 13 December 2012

Functional characterization of the Mycobacterium tuberculosis serine/threonine kinase PknJ

scientific journal article

Genetic analysis of new 16S rRNA mutations conferring aminoglycoside resistance in Mycobacterium abscessus

scientific article

Genetic basis for the biosynthesis of methylglucose lipopolysaccharides in Mycobacterium tuberculosis

scientific journal article

High content phenotypic cell-based visual screen identifies Mycobacterium tuberculosis acyltrehalose-containing glycolipids involved in phagosome remodeling

scientific journal article

High throughput phenotypic selection of Mycobacterium tuberculosis mutants with impaired resistance to reactive oxygen species identifies genes important for intracellular growth

scientific article

Horizontal Transfer of a Virulence Operon to the Ancestor of Mycobacterium tuberculosis

article

Horizontally acquired genomic islands in the tubercle bacilli

scientific article published on July 2008

Hyper-attenuated MTBVAC erp mutant protects against tuberculosis in mice

scientific article

Identification of DNA binding motifs of the Mycobacterium tuberculosis PhoP/PhoR two-component signal transduction system

scientific article

Identification of the required acyltransferase step in the biosynthesis of the phosphatidylinositol mannosides of mycobacterium species

scientific journal article

Innate immune response to Mycobacterium tuberculosis Beijing and other genotypes

scientific article

Interactions of attenuated Mycobacterium tuberculosis phoP mutant with human macrophages

scientific article

Intracellular replication of attenuated Mycobacterium tuberculosis phoP mutant in the absence of host cell cytotoxicity

scientific article

Is adipose tissue a place for Mycobacterium tuberculosis persistence?

scientific article

Isoxyl activation is required for bacteriostatic activity against Mycobacterium tuberculosis

scientific article

Length Variation of DC-SIGN and L-SIGN Neck-Region has no Impact on Tuberculosis Susceptibility

scientific article published on 04 December 2006

Long-chain multiple methyl-branched fatty acid-containing lipids of Mycobacterium tuberculosis: biosynthesis, transport, regulation and biological activities

scientific article published on 9 October 2006

LppX is a lipoprotein required for the translocation of phthiocerol dimycocerosates to the surface of Mycobacterium tuberculosis

scientific journal article

MVA.85A boosting of BCG and an attenuated, phoP deficient M. tuberculosis vaccine both show protective efficacy against tuberculosis in rhesus macaques

scientific article

Modification of the mycobacteriophage Ms6 attP core allows the integration of multiple vectors into different tRNAala T-loops in slow- and fast-growing mycobacteria

scientific article

Molecular detection of fluoroquinolone-resistance in multi-drug resistant tuberculosis in Cambodia suggests low association with XDR phenotypes

scientific article

Molecular recognition and interfacial catalysis by the essential phosphatidylinositol mannosyltransferase PimA from mycobacteria

scientific article

Multidrug-resistant Mycobacterium tuberculosis, Bangui, Central African Republic

scientific article published in September 2006

Mutations in putative mutator genes of Mycobacterium tuberculosis strains of the W-Beijing family

scientific article

Mycobacterial p(1)-type ATPases mediate resistance to zinc poisoning in human macrophages

scientific article published on September 2011

Mycobacterium abscessus: a new antibiotic nightmare

scientific article published on 30 January 2012

Mycobacterium tuberculosis Rv1395 is a class III transcriptional regulator of the AraC family involved in cytochrome P450 regulation

scientific journal article

Mycobacterium tuberculosis exploits the formation of new blood vessels for its dissemination

scientific article published on 12 September 2016

Mycobacterium tuberculosis phoP mutant: lipoarabinomannan molecular structure

scientific journal article

New tuberculosis vaccines

scientific article

Nitazoxanide Analogs Require Nitroreduction for Antimicrobial Activity in Mycobacterium smegmatis

scientific article

Phenotypic and genomic comparison of Mycobacterium aurum and surrogate model species to Mycobacterium tuberculosis: implications for drug discovery

scientific article

PhoP: a missing piece in the intricate puzzle of Mycobacterium tuberculosis virulence

scientific article

Phospholipases C are involved in the virulence of Mycobacterium tuberculosis

scientific journal article

Phylogeny of Mycobacterium tuberculosis Beijing strains constructed from polymorphisms in genes involved in DNA replication, recombination and repair

scientific article

Population variation in NAIP functional copy number confers increased cell death upon Legionella pneumophila infection

scientific article published on 23 October 2011

Prevalence and transmission of pyrazinamide resistant Mycobacterium tuberculosis in China

scientific article published on 3 March 2016

Probing host pathogen cross-talk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages

scientific article

Promoter and neck region length variation of DC-SIGN is not associated with susceptibility to tuberculosis in Tunisian patients

scientific article

Promoter variation in the DC-SIGN-encoding gene CD209 is associated with tuberculosis

scientific article

Recombinant Mycobacterium bovis BCG expressing the Sm14 antigen of Schistosoma mansoni protects mice from cercarial challenge

scientific article

Reduced local growth and spread but preserved pathogenicity of a DeltapurC Mycobacterium tuberculosis auxotrophic mutant in gamma interferon receptor-deficient mice after aerosol infection

scientific article

Signature-tagged transposon mutagenesis identifies novel Mycobacterium tuberculosis genes involved in the parasitism of human macrophages

scientific article published on 9 October 2006

Spoligotyping of clinical Mycobacterium tuberculosis isolates from the state of Minas Gerais, Brazil.

scientific article

Sulfolipid deficiency does not affect the virulence of Mycobacterium tuberculosis H37Rv in mice and guinea pigs

scientific article

Synthesis and biochemical evaluation of selective inhibitors of class II fructose bisphosphate aldolases: towards new synthetic antibiotics

scientific article

Systems approach to tuberculosis vaccine development

scientific article published on April 2013

T-cell and serological responses to Erp, an exported Mycobacterium tuberculosis protein, in tuberculosis patients and healthy individuals

scientific article

TNF-alpha is a critical negative regulator of type 1 immune activation during intracellular bacterial infection

scientific article

The Ser/Thr protein kinase PknB is essential for sustaining mycobacterial growth

scientific journal article

The allele encoding the mycobacterial Erp protein affects lung disease in mice

scientific journal article

The balance of apoptotic and necrotic cell death in Mycobacterium tuberculosis infected macrophages is not dependent on bacterial virulence

scientific article

The heritage of pathogen pressures and ancient demography in the human innate-immunity CD209/CD209L region

scientific article

The hydrophobic domain of the Mycobacterial Erp protein is not essential for the virulence of Mycobacterium tuberculosis

scientific article published on April 2004

The live Mycobacterium tuberculosis phoP mutant strain is more attenuated than BCG and confers protective immunity against tuberculosis in mice and guinea pigs

scientific article published on April 2006

The virulence-associated two-component PhoP-PhoR system controls the biosynthesis of polyketide-derived lipids in Mycobacterium tuberculosis

scientific journal article

Towards a crucial role for DC-SIGN in tuberculosis and beyond

scholarly article by Olivier Neyrolles et al published September 2006 in Trends in Microbiology

Transient requirement of the PrrA-PrrB two-component system for early intracellular multiplication of Mycobacterium tuberculosis

scientific journal article

Use of GeneXpert Remnants for Drug Resistance Profiling and Molecular Epidemiology of Tuberculosis in Libreville, Gabon

scientific article

Variation in gamma interferon responses to different infecting strains of Mycobacterium tuberculosis in acid-fast bacillus smear-positive patients and household contacts in Antananarivo, Madagascar

scientific article

Virulence attenuation of two Mas-like polyketide synthase mutants of Mycobacterium tuberculosis

scientific journal article

bacterial infection drives the expression dynamics of microRNAs and their isomiRs

scientific article

p-Hydroxybenzoic acid synthesis in Mycobacterium tuberculosis

scientific journal article

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