List of works - Donatella Malanga

AKT1E¹⁷K Is Oncogenic in Mouse Lung and Cooperates with Chemical Carcinogens in Inducing Lung Cancer

scientific article

Aberrant Signaling through the HER2-ERK1/2 Pathway is Predictive of Reduced Disease-Free and Overall Survival in Early Stage Non-Small Cell Lung Cancer (NSCLC) Patients

scientific article published on 15 January 2017

Activating E17K mutation in the gene encoding the protein kinase AKT1 in a subset of squamous cell carcinoma of the lung

scientific article published on 26 December 2007

Allelic variant at -79 (C>T) in CDKN1B (p27Kip1) confers an increased risk of thyroid cancer and alters mRNA levels.

scientific article

Analysis of miRNA profiles identified miR-196a as a crucial mediator of aberrant PI3K/AKT signaling in lung cancer cells.

scientific article published on 17 November 2016

Co-regulated expression of alpha and beta mRNAs encoding HLA-DR surface heterodimers is mediated by the MHCII RNA operon

scientific article published on 7 February 2013

Comparative analysis of new innovative vaccine formulations based on the use of procaryotic display systems

scientific article published on 5 December 2006

Contribution of PKB/AKT signaling to thyroid cancer

scientific article published on January 2011

Detection of Natural Resistance-Associated Substitutions by Ion Semiconductor Technology in HCV1b Positive, Direct-Acting Antiviral Agents-Naïve Patients

scientific article published on 27 August 2016

Effect of interferon alpha on MHC class II gene expression in ex vivo human islet tissue

article

Epithelial-to-mesenchymal transition in FHC-silenced cells: the role of CXCR4/CXCL12 axis.

scientific article published on 03 August 2017

Ferritin Heavy Subunit Silencing Blocks the Erythroid Commitment of K562 Cells via miR-150 up-Regulation and GATA-1 Repression

scientific article

Functional characterization of a rare germline mutation in the gene encoding the cyclin-dependent kinase inhibitor p27Kip1 (CDKN1B) in a Spanish patient with multiple endocrine neoplasia-like phenotype.

scientific article

Identification of copy number alterations in colon cancer from analysis of amplicon-based next generation sequencing data.

scientific article

Loss of p27 expression through RAS-->BRAF-->MAP kinase-dependent pathway in human thyroid carcinomas.

scientific article published on 13 August 2007

Multivisceral resection for occlusive colorectal cancer: Is it justified?

scientific article published on 8 July 2016

Mutant AKT1-E17K is oncogenic in lung epithelial cells

scientific article published on 25 May 2015

Next-generation sequencing analysis of receptor-type tyrosine kinase genes in surgically resected colon cancer: identification of gain-of-function mutations in the RET proto-oncogene

scientific article published on 17 April 2018

Nonredundant and locus-specific gene repression functions of PRC1 paralog family members in human hematopoietic stem/progenitor cells

scientific article published on 24 January 2013

Overexpression of the S-phase kinase-associated protein 2 in thyroid cancer

scientific article

PKC-dependent phosphorylation of p27 at T198 contributes to p27 stabilization and cell cycle arrest

scientific article

Signaling networks associated with AKT activation in non-small cell lung cancer (NSCLC): new insights on the role of phosphatydil-inositol-3 kinase

scientific article

Simultaneous identification of clinically relevant single nucleotide variants, copy number alterations and gene fusions in solid tumors by targeted next-generation sequencing.

scientific article published on 27 April 2018

Specific gene expression signatures induced by the multiple oncogenic alterations that occur within the PTEN/PI3K/AKT pathway in lung cancer

scientific article published on 29 June 2017

Spheres derived from lung adenocarcinoma pleural effusions: molecular characterization and tumor engraftment

scientific article (publication date: 2011)

The Akt1/IL-6/STAT3 pathway regulates growth of lung tumor initiating cells

scientific article published on 13 October 2015

The active translation of MHCII mRNA during dendritic cells maturation supplies new molecules to the cell surface pool

scientific article published on 01 April 2007

The nonreceptor-type tyrosine phosphatase PTPN13 is a tumor suppressor gene in non-small cell lung cancer

scientific article published on 13 January 2012

The role of CD133 in the identification and characterisation of tumour-initiating cells in non-small-cell lung cancer

scientific article

List of works by Donatella Malanga

AKT1E¹⁷K Is Oncogenic in Mouse Lung and Cooperates with Chemical Carcinogens in Inducing Lung Cancer

Aberrant Signaling through the HER2-ERK1/2 Pathway is Predictive of Reduced Disease-Free and Overall Survival in Early Stage Non-Small Cell Lung Cancer (NSCLC) Patients

Activating E17K mutation in the gene encoding the protein kinase AKT1 in a subset of squamous cell carcinoma of the lung

Allelic variant at -79 (C>T) in CDKN1B (p27Kip1) confers an increased risk of thyroid cancer and alters mRNA levels.

Analysis of miRNA profiles identified miR-196a as a crucial mediator of aberrant PI3K/AKT signaling in lung cancer cells.

Co-regulated expression of alpha and beta mRNAs encoding HLA-DR surface heterodimers is mediated by the MHCII RNA operon

Comparative analysis of new innovative vaccine formulations based on the use of procaryotic display systems

Contribution of PKB/AKT signaling to thyroid cancer

Detection of Natural Resistance-Associated Substitutions by Ion Semiconductor Technology in HCV1b Positive, Direct-Acting Antiviral Agents-Naïve Patients

Effect of interferon alpha on MHC class II gene expression in ex vivo human islet tissue

Epithelial-to-mesenchymal transition in FHC-silenced cells: the role of CXCR4/CXCL12 axis.

Ferritin Heavy Subunit Silencing Blocks the Erythroid Commitment of K562 Cells via miR-150 up-Regulation and GATA-1 Repression

Functional characterization of a rare germline mutation in the gene encoding the cyclin-dependent kinase inhibitor p27Kip1 (CDKN1B) in a Spanish patient with multiple endocrine neoplasia-like phenotype.

Identification of copy number alterations in colon cancer from analysis of amplicon-based next generation sequencing data.

Loss of p27 expression through RAS-->BRAF-->MAP kinase-dependent pathway in human thyroid carcinomas.

Multivisceral resection for occlusive colorectal cancer: Is it justified?

Mutant AKT1-E17K is oncogenic in lung epithelial cells

Next-generation sequencing analysis of receptor-type tyrosine kinase genes in surgically resected colon cancer: identification of gain-of-function mutations in the RET proto-oncogene

Nonredundant and locus-specific gene repression functions of PRC1 paralog family members in human hematopoietic stem/progenitor cells

Overexpression of the S-phase kinase-associated protein 2 in thyroid cancer

PKC-dependent phosphorylation of p27 at T198 contributes to p27 stabilization and cell cycle arrest

Signaling networks associated with AKT activation in non-small cell lung cancer (NSCLC): new insights on the role of phosphatydil-inositol-3 kinase

Simultaneous identification of clinically relevant single nucleotide variants, copy number alterations and gene fusions in solid tumors by targeted next-generation sequencing.

Specific gene expression signatures induced by the multiple oncogenic alterations that occur within the PTEN/PI3K/AKT pathway in lung cancer

Spheres derived from lung adenocarcinoma pleural effusions: molecular characterization and tumor engraftment

The Akt1/IL-6/STAT3 pathway regulates growth of lung tumor initiating cells

The active translation of MHCII mRNA during dendritic cells maturation supplies new molecules to the cell surface pool

The nonreceptor-type tyrosine phosphatase PTPN13 is a tumor suppressor gene in non-small cell lung cancer

The role of CD133 in the identification and characterisation of tumour-initiating cells in non-small-cell lung cancer