List of works - Paul R. Gooley

1H, 13C and 15N Resonance Assignments of the Cytosolic Domain of Tom20 from Arabidopsis thaliana

scientific article published in November 2005

1H, 13C and 15N backbone assignment and secondary structure of the 19 kDa diadenosine 5', 5'''-P1, P4-tetraphosphate hydrolase from Lupinus angustifolius L

scientific article published on 01 March 2000

1H, 13C and 15N resonance assignments of SMP-1: a small myristoylated protein from Leishmania major.

scientific article

1H, 13C, and 15N resonance assignments of the 17 kDa Ap4A hydrolase from Homo sapiens in the presence and absence of ATP.

scientific article

1H, 15N and 13C resonance assignments of the C-terminal domain of the P protein of the Nishigahara strain of rabies virus

1H-NMR analysis of the human urinary metabolome in response to an 18-month multi-component exercise program and calcium–vitamin-D3 supplementation in older men

article

A Cyclic Peptide Inhibitor of ApoC-II Peptide Fibril Formation: Mechanistic Insight from NMR and Molecular Dynamics Analysis

article

A Structural Core Within Apolipoprotein C-II Amyloid Fibrils Identified Using Hydrogen Exchange and Proteolysis

article

A Structural Model for Apolipoprotein C-II Amyloid Fibrils: Experimental Characterization and Molecular Dynamics Simulations

scientific article published in February 2011

A dynamic pharmacophore drives the interaction between Psalmotoxin-1 and the putative drug target acid-sensing ion channel 1a

scientific article

A high-resolution solution structure of a trypanosomatid FYVE domain

scientific article

A sample preparation protocol for 1H nuclear magnetic resonance studies of water-soluble metabolites in blood and urine

scientific article

A statistical approach to the interpretation of molecular dynamics simulations of calmodulin equilibrium dynamics

scientific article published in December 2005

AMP-activated protein kinase β-subunit requires internal motion for optimal carbohydrate binding

scientific article published on January 2012

AMPK beta subunits display isoform specific affinities for carbohydrates

scientific article

Acylation-dependent and-independent membrane targeting and distinct functions of small myristoylated proteins (SMPs) in Leishmania major

Automated NMR relaxation dispersion data analysis using NESSY

scientific article

Backbone resonance assignment of the 2H, 13C, 15N labelled 32kDa central domain of Escherichia coli TyrR

scientific article published on 01 April 2002

Characterisation of a cell-free synthesised G-protein coupled receptor

scientific article

Characterization of active-site residues in diadenosine tetraphosphate hydrolase from Lupinus angustifolius

scientific article

Charge and Charge-Pair Mutations Alter the Rate of Assembly and Structural Properties of Apolipoprotein C-II Amyloid Fibrils

scientific article published on 02 February 2015

Chimeric RXFP1 and RXFP2 Receptors Highlight the Similar Mechanism of Activation Utilizing Their N-Terminal Low-Density Lipoprotein Class A Modules.

scientific article

Co-regulation of the transcription controlling ATF2 phosphoswitch by JNK and p38

scientific article published on 13 November 2020

Comparison of amide proton exchange in reduced and oxidized Rhodobacter capsulatus cytochrome c2: a 1H-15N NMR study

scientific article published on July 1991

Conformational heterogeneity in polypeptide cardiac stimulants from sea anemones

scientific article published on 01 August 1984

Convergent Evolution of Receptors for Protein Import into Mitochondria

scientific article published in February 2006

Crystallization and preliminary X-ray diffraction studies of FHA domains of Dun1 and Rad53 protein kinases

article published in 2001

Definition of the immune evasion-replication interface of rabies virus P protein

scientific article published on 08 July 2021

Determinants of oligosaccharide specificity of the carbohydrate-binding modules of AMP-activated protein kinase

scientific article

Diazepam is not a direct allosteric modulator of α-adrenoceptors, but modulates receptor signaling by inhibiting phosphodiesterase-4

scientific article published on 26 December 2018

Discovery of inhibitors of lupin diadenosine 5',5'''-P(1),P(4)-tetraphosphate hydrolase by virtual screening.

scientific article

Distinct activation modes of the Relaxin Family Peptide Receptor 2 in response to insulin-like peptide 3 and relaxin

scientific article

Dynamics of Ca2+-saturated calmodulin D129N mutant studied by multiple molecular dynamics simulations

scientific article

Elucidation of relaxin-3 binding interactions in the extracellular loops of RXFP3.

scientific article published on 22 February 2013

Esterification of high amylose starch with short chain fatty acids modulates degradation by Bifidobacterium spp

High-level expression of a soluble and functional fibronectin type II domain from MMP-2 in the Escherichia coli cytoplasm for solution NMR studies.

scientific article published on 13 December 2006

Hydrodynamic radii of solubilized high amylose native and modified starches by pulsed field gradient NMR diffusion measurements

Hydrogen/Deuterium Exchange and Molecular Dynamics Analysis of Amyloid Fibrils Formed by a D69K Charge-Pair Mutant of Human Apolipoprotein C-II.

scientific article published on 21 July 2015

Identification and characterization of bi-thiazole-2,2'-diamines as kinase inhibitory scaffolds.

scientific article published on 11 February 2013

In a Class of Their Own - RXFP1 and RXFP2 are Unique Members of the LGR Family

scientific article

Intra- and Intersubunit Ion-Pair Interactions Determine the Ability of Apolipoprotein C-II Mutants To Form Hybrid Amyloid Fibrils.

scientific article published on 23 February 2017

Investigation of interactions at the extracellular loops of the relaxin family peptide receptor 1 (RXFP1).

scientific article

Macromolecular NMR spectroscopy for the non-spectroscopist: beyond macromolecular solution structure determination

scientific article published on 28 January 2011

Macromolecular NMR spectroscopy for the non‐spectroscopist ⬇️

scientific article published on January 28, 2011

Mapping key regions of the RXFP2 low-density lipoprotein class-A module that are involved in signal activation

scientific article published on 10 July 2014

Membrane protein SMP-1 is required for normal flagellum function in Leishmania

scientific article published on 19 January 2010

Membrane receptors: structure and function of the relaxin family peptide receptors

scientific article published on 06 February 2010

Membrane targeting of the small myristoylated protein 2 (SMP-2) in Leishmania major.

scientific article published on 30 May 2013

Metabolic profiling reveals anomalous energy metabolism and oxidative stress pathways in chronic fatigue syndrome patients

article

Metabolism in chronic fatigue syndrome

scientific article

Model-free model elimination: a new step in the model-free dynamic analysis of NMR relaxation data

scientific article

Molecular Insights into the Enigmatic Metabolic Regulator, SnRK1.

scientific article

Multiple heparin binding domains of respiratory syncytial virus G mediate binding to mammalian cells

scientific article published in October 2003

N- and C-terminal regions of αB-crystallin and Hsp27 mediate inhibition of amyloid nucleation, fibril binding, and fibril disaggregation

scientific article published on 16 May 2020

NMR metabolic profiling of serum identifies amino acid disturbances in chronic fatigue syndrome

scientific article published on 21 June 2012

Native Chemical Ligation to Minimize Aspartimide Formation during Chemical Synthesis of Small LDLa Protein

scientific article published on 27 November 2015

Oligosaccharide recognition and binding to the carbohydrate binding module of AMP-activated protein kinase

scientific article published on 29 September 2007

Optimisation of NMR dynamic models I. Minimisation algorithms and their performance within the model-free and Brownian rotational diffusion spaces

scientific article published on 18 December 2007

Optimisation of NMR dynamic models II. A new methodology for the dual optimisation of the model-free parameters and the Brownian rotational diffusion tensor

scientific article published on 18 December 2007

Patterns that define the four domains conserved in known and novel isoforms of the protein import receptor Tom20

scientific article (publication date: 18 March 2005)

Physical characterisation of high amylose maize starch and acylated high amylose maize starches

scientific article

Polymorphism in disease-related apolipoprotein C-II amyloid fibrils: a structural model for rod-like fibrils

scientific article published on 09 June 2018

Pro → Ala-35 Rhodobacter capsulatus cytochrome c 2 shows dynamic not structural differences

scientific article published on 01 January 1990

Probing the correlation between ligand efficacy and conformational diversity at the α1A-adrenoreceptor reveals allosteric coupling of its microswitches

scientific article published on 17 April 2020

Probing the flexibility of the DsbA oxidoreductase from Vibrio cholerae--a 15N - 1H heteronuclear NMR relaxation analysis of oxidized and reduced forms of DsbA

scientific article

Recognition and detoxification of the insecticide DDT by Drosophila melanogaster glutathione S-transferase D1.

scientific article published on 24 April 2010

Recognition of mitochondrial targeting sequences by the import receptors Tom20 and Tom22.

scientific article published on 16 November 2010

Regulation of Starch Stores by a Ca(2+)-Dependent Protein Kinase Is Essential for Viable Cyst Development in Toxoplasma gondii

scientific article published on December 2015

Set theory formulation of the model-free problem and the diffusion seeded model-free paradigm

article

Single fiber analyses of glycogen-related proteins reveal their differential association with glycogen in rat skeletal muscle

scientific article published on 26 September 2012

SnRK1 from Arabidopsis thaliana is an atypical AMPK.

scientific article

Solution Conditions Affect the Ability of the K30D Mutation To Prevent Amyloid Fibril Formation by Apolipoprotein C-II: Insights from Experiments and Theoretical Simulations.

scientific article published on 17 June 2016

Structural characterization of the N-terminal autoregulatory sequence of phenylalanine hydroxylase

scientific article

Structural insights into the multifunctionality of rabies virus P3 protein ⬇️

scientific article published on 29 March 2023

Structure and substrate-binding mechanism of human Ap4A hydrolase

scientific article

Structure of amylase-binding protein A of Streptococcus gordonii: a potential receptor for human salivary α-amylase enzyme

scientific article

Structure, topology and function of the translocase of the outer membrane of mitochondria

scientific article published on 03 January 2008

The NMR solution structure of the relaxin (RXFP1) receptor lipoprotein receptor class A module and identification of key residues in the N-terminal region of the module that mediate receptor activation

scientific article

The Transmembrane Segment of Tom20 Is Recognized by Mim1 for Docking to the Mitochondrial TOM Complex

scientific article published in February 2008

The association of fecal microbiota and fecal, blood serum and urine metabolites in myalgic encephalomyelitis/chronic fatigue syndrome

article

The complex binding mode of the peptide hormone H2 relaxin to its receptor RXFP1

scientific article published on 18 April 2016

The human LGR7 low-density lipoprotein class A module requires calcium for structure

scientific article

The interaction of human apolipoprotein C-I with sub-micellar phospholipid.

scientific article published in May 2001

The recruitment of AMP-activated protein kinase to glycogen is regulated by autophosphorylation

scientific article published on 19 March 2015

The relaxin receptor (RXFP1) utilizes hydrophobic moieties on a signaling surface of its N-terminal low density lipoprotein class A module to mediate receptor activation.

scientific article

The role of select subtype polymorphisms on HIV-1 protease conformational sampling and dynamics

scientific article (publication date: 13 June 2014)

The structure and interactions of human apolipoprotein C-II in dodecyl phosphocholine

scientific article

The structure of Ap(4)A hydrolase complexed with ATP-MgF(x) reveals the basis of substrate binding

scientific article

The structure of the extracellular domains of human interleukin 11 α-receptor reveals mechanisms of cytokine engagement

scientific article published on 24 April 2020

The three-dimensional structure of the Nudix enzyme diadenosine tetraphosphate hydrolase from Lupinus angustifolius L

scientific article

The use of model selection in the model-free analysis of protein dynamics

article

Thienopyridone drugs are selective activators of AMP-activated protein kinase beta1-containing complexes.

scientific article published in November 2008

Unravelling the Carbohydrate-Binding Preferences of the Carbohydrate-Binding Modules of AMP-Activated Protein Kinase.

scientific article published on 30 November 2017

Validating the use of database potentials in protein structure determination by NMR.

scientific article

When phosphorylated at Thr148, the β2-subunit of AMP-activated kinase does not associate with glycogen in skeletal muscle

scientific article published on 20 April 2016

relaxGUI: a new software for fast and simple NMR relaxation data analysis and calculation of ps-ns and μs motion of proteins

scientific article

β-subunit myristoylation functions as an energy sensor by modulating the dynamics of AMP-activated Protein Kinase

scientific article published on 21 December 2016

List of works by Paul R. Gooley

1H, 13C and 15N Resonance Assignments of the Cytosolic Domain of Tom20 from Arabidopsis thaliana

1H, 13C and 15N backbone assignment and secondary structure of the 19 kDa diadenosine 5', 5'''-P1, P4-tetraphosphate hydrolase from Lupinus angustifolius L

1H, 13C and 15N resonance assignments of SMP-1: a small myristoylated protein from Leishmania major.

1H, 13C, and 15N resonance assignments of the 17 kDa Ap4A hydrolase from Homo sapiens in the presence and absence of ATP.

1H, 15N and 13C resonance assignments of the C-terminal domain of the P protein of the Nishigahara strain of rabies virus

1H-NMR analysis of the human urinary metabolome in response to an 18-month multi-component exercise program and calcium–vitamin-D3 supplementation in older men

A Cyclic Peptide Inhibitor of ApoC-II Peptide Fibril Formation: Mechanistic Insight from NMR and Molecular Dynamics Analysis

A Structural Core Within Apolipoprotein C-II Amyloid Fibrils Identified Using Hydrogen Exchange and Proteolysis

A Structural Model for Apolipoprotein C-II Amyloid Fibrils: Experimental Characterization and Molecular Dynamics Simulations

A dynamic pharmacophore drives the interaction between Psalmotoxin-1 and the putative drug target acid-sensing ion channel 1a

A high-resolution solution structure of a trypanosomatid FYVE domain

A sample preparation protocol for 1H nuclear magnetic resonance studies of water-soluble metabolites in blood and urine

A statistical approach to the interpretation of molecular dynamics simulations of calmodulin equilibrium dynamics

AMP-activated protein kinase β-subunit requires internal motion for optimal carbohydrate binding

AMPK beta subunits display isoform specific affinities for carbohydrates

Acylation-dependent and-independent membrane targeting and distinct functions of small myristoylated proteins (SMPs) in Leishmania major

Automated NMR relaxation dispersion data analysis using NESSY

Backbone resonance assignment of the 2H, 13C, 15N labelled 32kDa central domain of Escherichia coli TyrR

Characterisation of a cell-free synthesised G-protein coupled receptor

Characterization of active-site residues in diadenosine tetraphosphate hydrolase from Lupinus angustifolius

Charge and Charge-Pair Mutations Alter the Rate of Assembly and Structural Properties of Apolipoprotein C-II Amyloid Fibrils

Chimeric RXFP1 and RXFP2 Receptors Highlight the Similar Mechanism of Activation Utilizing Their N-Terminal Low-Density Lipoprotein Class A Modules.

Co-regulation of the transcription controlling ATF2 phosphoswitch by JNK and p38

Comparison of amide proton exchange in reduced and oxidized Rhodobacter capsulatus cytochrome c2: a 1H-15N NMR study

Conformational heterogeneity in polypeptide cardiac stimulants from sea anemones

Convergent Evolution of Receptors for Protein Import into Mitochondria

Crystallization and preliminary X-ray diffraction studies of FHA domains of Dun1 and Rad53 protein kinases

Definition of the immune evasion-replication interface of rabies virus P protein

Determinants of oligosaccharide specificity of the carbohydrate-binding modules of AMP-activated protein kinase

Diazepam is not a direct allosteric modulator of α-adrenoceptors, but modulates receptor signaling by inhibiting phosphodiesterase-4

Discovery of inhibitors of lupin diadenosine 5',5'''-P(1),P(4)-tetraphosphate hydrolase by virtual screening.

Distinct activation modes of the Relaxin Family Peptide Receptor 2 in response to insulin-like peptide 3 and relaxin

Dynamics of Ca2+-saturated calmodulin D129N mutant studied by multiple molecular dynamics simulations

Elucidation of relaxin-3 binding interactions in the extracellular loops of RXFP3.

Esterification of high amylose starch with short chain fatty acids modulates degradation by Bifidobacterium spp

High-level expression of a soluble and functional fibronectin type II domain from MMP-2 in the Escherichia coli cytoplasm for solution NMR studies.

Hydrodynamic radii of solubilized high amylose native and modified starches by pulsed field gradient NMR diffusion measurements

Hydrogen/Deuterium Exchange and Molecular Dynamics Analysis of Amyloid Fibrils Formed by a D69K Charge-Pair Mutant of Human Apolipoprotein C-II.

Identification and characterization of bi-thiazole-2,2'-diamines as kinase inhibitory scaffolds.

In a Class of Their Own - RXFP1 and RXFP2 are Unique Members of the LGR Family

Intra- and Intersubunit Ion-Pair Interactions Determine the Ability of Apolipoprotein C-II Mutants To Form Hybrid Amyloid Fibrils.

Investigation of interactions at the extracellular loops of the relaxin family peptide receptor 1 (RXFP1).

Macromolecular NMR spectroscopy for the non-spectroscopist: beyond macromolecular solution structure determination

Macromolecular NMR spectroscopy for the non‐spectroscopist ⬇️

Mapping key regions of the RXFP2 low-density lipoprotein class-A module that are involved in signal activation

Membrane protein SMP-1 is required for normal flagellum function in Leishmania

Membrane receptors: structure and function of the relaxin family peptide receptors

Membrane targeting of the small myristoylated protein 2 (SMP-2) in Leishmania major.

Metabolic profiling reveals anomalous energy metabolism and oxidative stress pathways in chronic fatigue syndrome patients

Metabolism in chronic fatigue syndrome

Model-free model elimination: a new step in the model-free dynamic analysis of NMR relaxation data

Molecular Insights into the Enigmatic Metabolic Regulator, SnRK1.

Multiple heparin binding domains of respiratory syncytial virus G mediate binding to mammalian cells

N- and C-terminal regions of αB-crystallin and Hsp27 mediate inhibition of amyloid nucleation, fibril binding, and fibril disaggregation

NMR metabolic profiling of serum identifies amino acid disturbances in chronic fatigue syndrome

Native Chemical Ligation to Minimize Aspartimide Formation during Chemical Synthesis of Small LDLa Protein

Oligosaccharide recognition and binding to the carbohydrate binding module of AMP-activated protein kinase

Optimisation of NMR dynamic models I. Minimisation algorithms and their performance within the model-free and Brownian rotational diffusion spaces

Optimisation of NMR dynamic models II. A new methodology for the dual optimisation of the model-free parameters and the Brownian rotational diffusion tensor

Patterns that define the four domains conserved in known and novel isoforms of the protein import receptor Tom20

Physical characterisation of high amylose maize starch and acylated high amylose maize starches

Polymorphism in disease-related apolipoprotein C-II amyloid fibrils: a structural model for rod-like fibrils

Pro → Ala-35 Rhodobacter capsulatus cytochrome c 2 shows dynamic not structural differences

Probing the correlation between ligand efficacy and conformational diversity at the α1A-adrenoreceptor reveals allosteric coupling of its microswitches

Probing the flexibility of the DsbA oxidoreductase from Vibrio cholerae--a 15N - 1H heteronuclear NMR relaxation analysis of oxidized and reduced forms of DsbA

Recognition and detoxification of the insecticide DDT by Drosophila melanogaster glutathione S-transferase D1.

Recognition of mitochondrial targeting sequences by the import receptors Tom20 and Tom22.

Regulation of Starch Stores by a Ca(2+)-Dependent Protein Kinase Is Essential for Viable Cyst Development in Toxoplasma gondii

Set theory formulation of the model-free problem and the diffusion seeded model-free paradigm

Single fiber analyses of glycogen-related proteins reveal their differential association with glycogen in rat skeletal muscle

SnRK1 from Arabidopsis thaliana is an atypical AMPK.

Solution Conditions Affect the Ability of the K30D Mutation To Prevent Amyloid Fibril Formation by Apolipoprotein C-II: Insights from Experiments and Theoretical Simulations.

Structural characterization of the N-terminal autoregulatory sequence of phenylalanine hydroxylase

Structural insights into the multifunctionality of rabies virus P3 protein ⬇️

Structure and substrate-binding mechanism of human Ap4A hydrolase

Structure of amylase-binding protein A of Streptococcus gordonii: a potential receptor for human salivary α-amylase enzyme

Structure, topology and function of the translocase of the outer membrane of mitochondria

The NMR solution structure of the relaxin (RXFP1) receptor lipoprotein receptor class A module and identification of key residues in the N-terminal region of the module that mediate receptor activation

The Transmembrane Segment of Tom20 Is Recognized by Mim1 for Docking to the Mitochondrial TOM Complex