List of works - Brian J. Harvey

17Beta-estradiol inhibits IL-8 in cystic fibrosis by up-regulating secretory leucoprotease inhibitor

scientific article published on 8 April 2010

17beta-Estradiol rapidly stimulates c-fos expression via the MAPK pathway in T84 cells

scientific article published in January 2005

17beta-estradiol rapidly mobilizes intracellular calcium from ryanodine-receptor-gated stores via a PKC-PKA-Erk-dependent pathway in the human eccrine sweat gland cell line NCL-SG3.

scientific article published on 22 January 2008

17beta-oestradiol acutely regulates Cl- secretion in rat distal colonic epithelium

scientific article

17beta-oestradiol stimulates capacitative Ca2+ entry in human endometrial cells.

scientific article

A Galphas protein-coupled membrane receptor, distinct from the classical oestrogen receptor, transduces rapid effects of oestradiol on [Ca2+]i in female rat distal colon

scientific article published on January 2003

A proposed integrated approach for the preclinical evaluation of phage therapy in Pseudomonas infections.

scientific article

Acid secretion through the Rana esculenta skin: involvement of an anion-exchange mechanism at the basolateral membrane

scientific article

Activation of P2RY11 and ATP release by lipoxin A4 restores the airway surface liquid layer and epithelial repair in cystic fibrosis

scientific article published on August 2014

Activation of stretch-activated channels and maxi-K+ channels by membrane stress of human lamina cribrosa cells

scientific article published on 4 September 2008

Aldosterone Rapidly Activates Na + /H + Exchange in M-1 Cortical Collecting Duct Cells via a PKC-MAPK Pathway

scientific article published on 01 January 2005

Aldosterone rapidly activates protein kinase D via a mineralocorticoid receptor/EGFR trans-activation pathway in the M1 kidney CCD cell line.

scientific article published on 22 June 2007

Aldosterone regulates rapid trafficking of epithelial sodium channel subunits in renal cortical collecting duct cells via protein kinase D activation.

scientific article published on 17 January 2008

Aldosterone-induced ENaC and basal Na+/K+-ATPase trafficking via protein kinase D1-phosphatidylinositol 4-kinaseIIIβ trans Golgi signalling in M1 cortical collecting duct cells

scientific article published on 26 March 2013

Aldosterone-induced protein kinase signalling and the control of electrolyte balance.

scientific article published on 24 October 2017

Aldosterone-induced signalling and cation transport in the distal nephron.

scientific article published on 19 January 2008

Berberine Reduces cAMP-Induced Chloride Secretion in T84 Human Colonic Carcinoma Cells through Inhibition of Basolateral KCNQ1 Channels.

scientific article

Berberine inhibits ion transport in human colonic epithelia

scientific article published on February 1999

Bidirectional KCNQ1:β-catenin interaction drives colorectal cancer cell differentiation

scientific article

Bile acids stimulate chloride secretion through CFTR and calcium-activated Cl- channels in Calu-3 airway epithelial cells

scientific article published on 3 July 2014

CFTR regulation of intracellular calcium in normal and cystic fibrosis human airway epithelia

scientific article

Cellular mechanisms for apical ATP effects on intracellular pH in human bronchial epithelium

scientific article published on August 2002

Chloride and non-selective cation channels in unstimulated trout red blood cells

scientific article published in August 1998

Chloride dependent intracellular pH effects of external ATP in cultured human non-pigmented ciliary body epithelium

scientific article published in December 2001

Cl− permeability of the basolateral membrane of the Rana esculenta epithelium: activation of Cl−/HCO3− exchange by alkaline intracellular pH

scientific article published on 01 March 1991

Cytosolic phospholipase A2 activation correlates with HER2 overexpression and mediates estrogen-dependent breast cancer cell growth.

scientific article

Cytosolic phospholipase A2-α expression in breast cancer is associated with EGFR expression and correlates with an adverse prognosis in luminal tumours.

scientific article

Dataset of KCNQ1, KCNN4, KATP channel expression and dexamethasone modulation of protein kinase signaling in airway epithelial cells

scientific article published on 22 October 2019

Dexamethasone reduces airway epithelial Cl- secretion by rapid non-genomic inhibition of KCNQ1, KCNN4 and KATP K+ channels

scientific article published on 19 July 2019

Differential p16/INK4A cyclin-dependent kinase inhibitor expression correlates with chemotherapy efficacy in a cohort of 88 malignant pleural mesothelioma patients

scientific article

Direct binding and activation of protein kinase C isoforms by aldosterone and 17beta-estradiol

scientific article published on 31 July 2007

Effect of estrogen on pseudomonas mucoidy and exacerbations in cystic fibrosis

scientific article published on 20 May 2012

Effect of mucosal H+ and chemical modification on transcellular K+ current in frog skin.

scientific article published in May 1990

Effects of Bark Beetle Outbreaks on Forest Landscape Pattern in the Southern Rocky Mountains, U.S.A.

Effects of intracellular signals on Na+/K+-ATPase pump activity in the frog skin epithelium

scientific article published on 01 April 1992

Electrogenic active proton pump in Rana esculenta skin and its role in sodium ion transport.

scientific article

Eosinophil peroxidase activates cells by HER2 receptor engagement and β1-integrin clustering with downstream MAPK cell signaling

scientific article published on 9 August 2016

Eosinophil peroxidase induces the expression and function of acid-sensing ion channel-3 in allergic rhinitis: in vitro evidence in cultured epithelial cells.

scientific article

Estradiol rapidly induces the translocation and activation of the intermediate conductance calcium activated potassium channel in human eccrine sweat gland cells

scientific article

Estrogen Reduces Lipid Content in the Liver Exclusively from Membrane Receptor Signaling ⬇️

scientific article published on May 21, 2013

Estrogen and the cystic fibrosis gender gap.

scientific article published on 14 December 2013

Estrogen increases ENaC activity via PKCδ signaling in renal cortical collecting duct cells

scientific article

Estrogen induces phospholipase A2 activation through ERK1/2 to mobilize intracellular calcium in MCF-7 cells

scientific article published on 22 December 2005

Estrogen inhibits chloride secretion caused by cholera and Escherichia coli enterotoxins in female rat distal colon

scientific article published on 8 May 2011

Estrogen receptor α regulates tripartite motif-containing protein 21 expression, contributing to dysregulated cytokine production in systemic lupus erythematosus.

scientific article published in January 2014

Estrogen receptor β exerts tumor repressive functions in human malignant pleural mesothelioma via EGFR inactivation and affects response to gefitinib

scientific article

Estrogen regulation of epithelial ion transport: Implications in health and disease.

scientific article published on 05 March 2012

Estrogen, phospholipase A and breast cancer.

scientific article published on January 2008

Evidence for a Na+/H+ exchanger at the basolateral membranes of the isolated frog skin epithelium: effect of amiloride analogues

scientific article published in June 1987

Expression and function of the epithelial sodium channel δ-subunit in human respiratory epithelial cells in vitro

scientific article published on 13 February 2015

Extracellular ATP effects on calcium signaling in cultured human non-pigmented ciliary body epithelium

scientific article published in December 2001

Female gender-specific inhibition of KCNQ1 channels and chloride secretion by 17beta-estradiol in rat distal colonic crypts

scientific article published on 7 June 2007

Gender differences in rates of carriage and bloodstream infection caused by methicillin-resistant Staphylococcus aureus: are they real, do they matter and why?

scientific article published on 22 July 2015

Histamine-induced cytosolic calcium increase in porcine articular chondrocytes

scientific article published on 01 August 1996

Inhibition of Protease-Epithelial Sodium Channel Signaling Improves Mucociliary Function in Cystic Fibrosis Airways.

scientific article published on 25 March 2016

Intracellular ion activities in frog skin in relation to external sodium and effects of amiloride and/or ouabain.

scientific article

Ion-selective micro-electrode studies of the electrochemical potentials in trout urinary bladder.

scientific article published in January 1986

Irish thoracic society

article

JNK mitogen-activated protein kinase limits calcium-dependent chloride secretion across colonic epithelial cells.

scientific article published on 29 October 2009

KCNQ1: a new regulator of the epithelio-mesenchymal transition in colorectal cancers

scientific article published on 31 January 2018

Launch sites

book chapter

Lipoxin A4 prevents tight junction disruption and delays the colonization of cystic fibrosis bronchial epithelial cells by Pseudomonas aeruginosa.

scientific article published on 15 April 2016

Lipoxin A4 stimulates calcium-activated chloride currents and increases airway surface liquid height in normal and cystic fibrosis airway epithelia

scientific article

Lipoxin A₄-mediated KATP potassium channel activation results in cystic fibrosis airway epithelial repair.

scientific article published on 17 May 2013

Malignant pleural mesothelioma incidence and survival in the Republic of Ireland 1994–2009

scientific article published on 04 January 2014

Maxi K+ channels in the basolateral membrane of the exocrine frog skin gland regulated by intracellular calcium and pH

scientific article published on 01 November 1995

Mechanisms underlying rapid aldosterone effects in the kidney

scientific article

Mechanosensitive calcium entry and mobilization in renal A6 cells

scientific article published on March 1999

Membrane ERalpha-dependent activation of PKCalpha in endometrial cancer cells by estradiol.

scientific article

Mitogenic effects of oestrogen mediated by a non-genomic receptor in human colon

article

Modulation of cytosolic protein kinase C and calcium ion activity by steroid hormones in rat distal colon

scientific article

Modulation of the protein kinase Cdelta interaction with the "d" subunit of F1F0-ATP synthase in neonatal cardiac myocytes: development of cell-permeable, mitochondrially targeted inhibitor and facilitator peptides.

scientific article

Non-genomic actions of aldosterone: from receptors and signals to membrane targets.

scientific article

Non-genomic convergent and divergent signalling of rapid responses to aldosterone and estradiol in mammalian colon

scientific article

Non-genomic estrogen regulation of ion transport and airway surface liquid dynamics in cystic fibrosis bronchial epithelium

scientific article

Nongenomic effects of aldosterone on Ca2+ in M-1 cortical collecting duct cells

scientific article

Novel aspects of oestrogen actions

scientific article published on 01 November 2009

Novel female sex-dependent actions of oestrogen in the intestine.

scientific article published on September 2009

Oestrogen promotes KCNQ1 potassium channel endocytosis and postendocytic trafficking in colonic epithelium

scientific article

P. aeruginosa LPS stimulates calcium signaling and chloride secretion via CFTR in human bronchial epithelial cells

scientific article

Physiological levels of lipoxin A4 inhibit ENaC and restore airway surface liquid height in cystic fibrosis bronchial epithelium

scientific article

Physiological techniques in the study of rapid aldosterone effects.

scientific article published on January 2014

Position paper: Rapid responses to steroids: current status and future prospects.

scientific article published on March 2010

Proceedings of the Fifth International Meeting on Rapid Responses to Steroid Hormones

article

Protein kinase D stabilizes aldosterone-induced ERK1/2 MAP kinase activation in M1 renal cortical collecting duct cells to promote cell proliferation

scientific article published on 3 October 2009

Protein kinase D1 modulates aldosterone-induced ENaC activity in a renal cortical collecting duct cell line

scientific article

Pseudomonas aeruginosa PA5oct Jumbo Phage Impacts Planktonic and Biofilm Population and Reduces Its Host Virulence

scientific article published on 23 November 2019

Rapid Responses to Steroid Hormones in the Kidney

article

Rapid aldosterone actions on epithelial sodium channel trafficking and cell proliferation

scientific article published on 20 November 2013

Rapid and non-genomic reduction of intracellular [Ca(2+)] induced by aldosterone in human bronchial epithelium

scientific article

Rapid effects of 17beta-estradiol on TRPV5 epithelial Ca2+ channels in rat renal cells.

scientific article

Rapid effects of 17beta-estradiol on epithelial TRPV6 Ca2+ channel in human T84 colonic cells.

scientific article

Rapid effects of aldosterone on sodium-hydrogen exchange in isolated colonic crypts.

scientific article

Rapid effects of corticosteroids on cytosolic protein kinase C and intracellular calcium concentration in human distal colon

scientific article published on March 1998

Rapid effects of dexamethasone on intracellular pH and Na+/H+ exchanger activity in human bronchial epithelial cells.

scientific article

Rapid non-genomic inhibition of ATP-induced Cl- secretion by dexamethasone in human bronchial epithelium.

scientific article published on December 2002

Rapid responses to aldosterone in human distal colon

article

Rapid responses to aldosterone in the kidney and colon.

scientific article

Reduced 15-lipoxygenase 2 and lipoxin A4/leukotriene B4 ratio in children with cystic fibrosis

scientific article published on 2 April 2014

Regulation of intracellular Ca(2+) by CFTR in Chinese hamster ovary cells

scientific article published in October 1999

Regulation of intracellular sodium and pH by the electrogenic H+ pump in frog skin

scientific article published in April 1986

Renin-angiotensin system expression and secretory function in cultured human ciliary body non-pigmented epithelium.

scientific article

Resolvin D1 regulates epithelial ion transport and inflammation in cystic fibrosis airways

scientific article

Royal academy of medicine in ireland section of biomedical sciences

Sex and estrous cycle-dependent rapid protein kinase signaling actions of estrogen in distal colonic cells.

scientific article published on 08 February 2008

Sodium-selective micro-electrode study of apical permeability in frog skin: effects of sodium, amiloride and ouabain

scientific article published in November 1984

Sustained Expression of Steroid Receptor Coactivator SRC-2/TIF-2 is Associated with Better Prognosis in Malignant Pleural Mesothelioma ⬇️

scientific article published on January 1, 2012

Tamoxifen Suppresses the Growth of Malignant Pleural Mesothelioma Cells.

scientific article published on November 2016

The effect of high [K(+)]o on spontaneous Ca(2+) waves in freshly isolated interstitial cells of Cajal from the rabbit urethra

scientific article published on 21 January 2014

The key role of the mitochondria-rich cell in Na+ and H+ transport across the frog skin epithelium

scientific article

The regulation of cell growth and survival by aldosterone

scientific article published on January 2011

The role of Ca(2+) influx in spontaneous Ca(2+) wave propagation in interstitial cells of Cajal from the rabbit urethra.

scientific article published on 26 June 2015

The role of cAMP dependent protein kinase in modulating spontaneous intracellular Ca²⁺ waves in interstitial cells of Cajal from the rabbit urethra

scientific article published on 10 July 2014

Ursodeoxycholic acid inhibits ENaC and Na/K pump activity to restore airway surface liquid height in cystic fibrosis bronchial epithelial cells

scientific article published on 22 July 2019

Volume-activated DIDS-sensitive whole-cell chloride currents in trout red blood cells

scientific article published on 01 October 1997

List of works by Brian J. Harvey

17Beta-estradiol inhibits IL-8 in cystic fibrosis by up-regulating secretory leucoprotease inhibitor

17beta-Estradiol rapidly stimulates c-fos expression via the MAPK pathway in T84 cells

17beta-estradiol rapidly mobilizes intracellular calcium from ryanodine-receptor-gated stores via a PKC-PKA-Erk-dependent pathway in the human eccrine sweat gland cell line NCL-SG3.

17beta-oestradiol acutely regulates Cl- secretion in rat distal colonic epithelium

17beta-oestradiol stimulates capacitative Ca2+ entry in human endometrial cells.

A Galphas protein-coupled membrane receptor, distinct from the classical oestrogen receptor, transduces rapid effects of oestradiol on [Ca2+]i in female rat distal colon

A proposed integrated approach for the preclinical evaluation of phage therapy in Pseudomonas infections.

Acid secretion through the Rana esculenta skin: involvement of an anion-exchange mechanism at the basolateral membrane

Activation of P2RY11 and ATP release by lipoxin A4 restores the airway surface liquid layer and epithelial repair in cystic fibrosis

Activation of stretch-activated channels and maxi-K+ channels by membrane stress of human lamina cribrosa cells

Aldosterone Rapidly Activates Na + /H + Exchange in M-1 Cortical Collecting Duct Cells via a PKC-MAPK Pathway

Aldosterone rapidly activates protein kinase D via a mineralocorticoid receptor/EGFR trans-activation pathway in the M1 kidney CCD cell line.

Aldosterone regulates rapid trafficking of epithelial sodium channel subunits in renal cortical collecting duct cells via protein kinase D activation.

Aldosterone-induced ENaC and basal Na+/K+-ATPase trafficking via protein kinase D1-phosphatidylinositol 4-kinaseIIIβ trans Golgi signalling in M1 cortical collecting duct cells

Aldosterone-induced protein kinase signalling and the control of electrolyte balance.

Aldosterone-induced signalling and cation transport in the distal nephron.

Berberine Reduces cAMP-Induced Chloride Secretion in T84 Human Colonic Carcinoma Cells through Inhibition of Basolateral KCNQ1 Channels.

Berberine inhibits ion transport in human colonic epithelia

Bidirectional KCNQ1:β-catenin interaction drives colorectal cancer cell differentiation

Bile acids stimulate chloride secretion through CFTR and calcium-activated Cl- channels in Calu-3 airway epithelial cells

CFTR regulation of intracellular calcium in normal and cystic fibrosis human airway epithelia

Cellular mechanisms for apical ATP effects on intracellular pH in human bronchial epithelium

Chloride and non-selective cation channels in unstimulated trout red blood cells

Chloride dependent intracellular pH effects of external ATP in cultured human non-pigmented ciliary body epithelium

Cl− permeability of the basolateral membrane of the Rana esculenta epithelium: activation of Cl−/HCO3− exchange by alkaline intracellular pH

Cytosolic phospholipase A2 activation correlates with HER2 overexpression and mediates estrogen-dependent breast cancer cell growth.

Cytosolic phospholipase A2-α expression in breast cancer is associated with EGFR expression and correlates with an adverse prognosis in luminal tumours.

Dataset of KCNQ1, KCNN4, KATP channel expression and dexamethasone modulation of protein kinase signaling in airway epithelial cells

Dexamethasone reduces airway epithelial Cl- secretion by rapid non-genomic inhibition of KCNQ1, KCNN4 and KATP K+ channels

Differential p16/INK4A cyclin-dependent kinase inhibitor expression correlates with chemotherapy efficacy in a cohort of 88 malignant pleural mesothelioma patients

Direct binding and activation of protein kinase C isoforms by aldosterone and 17beta-estradiol

Effect of estrogen on pseudomonas mucoidy and exacerbations in cystic fibrosis

Effect of mucosal H+ and chemical modification on transcellular K+ current in frog skin.

Effects of Bark Beetle Outbreaks on Forest Landscape Pattern in the Southern Rocky Mountains, U.S.A.

Effects of intracellular signals on Na+/K+-ATPase pump activity in the frog skin epithelium

Electrogenic active proton pump in Rana esculenta skin and its role in sodium ion transport.

Eosinophil peroxidase activates cells by HER2 receptor engagement and β1-integrin clustering with downstream MAPK cell signaling

Eosinophil peroxidase induces the expression and function of acid-sensing ion channel-3 in allergic rhinitis: in vitro evidence in cultured epithelial cells.

Estradiol rapidly induces the translocation and activation of the intermediate conductance calcium activated potassium channel in human eccrine sweat gland cells

Estrogen Reduces Lipid Content in the Liver Exclusively from Membrane Receptor Signaling ⬇️

Estrogen and the cystic fibrosis gender gap.

Estrogen increases ENaC activity via PKCδ signaling in renal cortical collecting duct cells

Estrogen induces phospholipase A2 activation through ERK1/2 to mobilize intracellular calcium in MCF-7 cells

Estrogen inhibits chloride secretion caused by cholera and Escherichia coli enterotoxins in female rat distal colon

Estrogen receptor α regulates tripartite motif-containing protein 21 expression, contributing to dysregulated cytokine production in systemic lupus erythematosus.

Estrogen receptor β exerts tumor repressive functions in human malignant pleural mesothelioma via EGFR inactivation and affects response to gefitinib

Estrogen regulation of epithelial ion transport: Implications in health and disease.

Estrogen, phospholipase A and breast cancer.

Evidence for a Na+/H+ exchanger at the basolateral membranes of the isolated frog skin epithelium: effect of amiloride analogues

Expression and function of the epithelial sodium channel δ-subunit in human respiratory epithelial cells in vitro

Extracellular ATP effects on calcium signaling in cultured human non-pigmented ciliary body epithelium

Female gender-specific inhibition of KCNQ1 channels and chloride secretion by 17beta-estradiol in rat distal colonic crypts

Gender differences in rates of carriage and bloodstream infection caused by methicillin-resistant Staphylococcus aureus: are they real, do they matter and why?

Histamine-induced cytosolic calcium increase in porcine articular chondrocytes

Inhibition of Protease-Epithelial Sodium Channel Signaling Improves Mucociliary Function in Cystic Fibrosis Airways.

Intracellular ion activities in frog skin in relation to external sodium and effects of amiloride and/or ouabain.

Ion-selective micro-electrode studies of the electrochemical potentials in trout urinary bladder.

Irish thoracic society

JNK mitogen-activated protein kinase limits calcium-dependent chloride secretion across colonic epithelial cells.

KCNQ1: a new regulator of the epithelio-mesenchymal transition in colorectal cancers

Launch sites

Lipoxin A4 prevents tight junction disruption and delays the colonization of cystic fibrosis bronchial epithelial cells by Pseudomonas aeruginosa.

Lipoxin A4 stimulates calcium-activated chloride currents and increases airway surface liquid height in normal and cystic fibrosis airway epithelia

Lipoxin A₄-mediated KATP potassium channel activation results in cystic fibrosis airway epithelial repair.

Malignant pleural mesothelioma incidence and survival in the Republic of Ireland 1994–2009

Maxi K+ channels in the basolateral membrane of the exocrine frog skin gland regulated by intracellular calcium and pH

Mechanisms underlying rapid aldosterone effects in the kidney

Mechanosensitive calcium entry and mobilization in renal A6 cells

Membrane ERalpha-dependent activation of PKCalpha in endometrial cancer cells by estradiol.

Mitogenic effects of oestrogen mediated by a non-genomic receptor in human colon

Modulation of cytosolic protein kinase C and calcium ion activity by steroid hormones in rat distal colon

Modulation of the protein kinase Cdelta interaction with the "d" subunit of F1F0-ATP synthase in neonatal cardiac myocytes: development of cell-permeable, mitochondrially targeted inhibitor and facilitator peptides.

Non-genomic actions of aldosterone: from receptors and signals to membrane targets.

Non-genomic convergent and divergent signalling of rapid responses to aldosterone and estradiol in mammalian colon

Non-genomic estrogen regulation of ion transport and airway surface liquid dynamics in cystic fibrosis bronchial epithelium

Nongenomic effects of aldosterone on Ca2+ in M-1 cortical collecting duct cells

Novel aspects of oestrogen actions

Novel female sex-dependent actions of oestrogen in the intestine.

Oestrogen promotes KCNQ1 potassium channel endocytosis and postendocytic trafficking in colonic epithelium