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List of works by Angel Nadal

A Calcium-Dependent Chloride Current Increases Repetitive Firing in Mouse Sympathetic Neurons.

scientific article published on 14 May 2018

A role for the putative cannabinoid receptor GPR55 in the islets of Langerhans.

scientific article

A vision for safer food contact materials: Public health concerns as drivers for improved testing

scientific article published in October 2023

A water-soluble perylene dye functionalised with a 17β-estradiol: a new fluorescent tool for steroid hormones

scientific article published on 20 June 2011

Actions of serum and plasma albumin on intracellular Ca2+ in human endothelial cells

scientific article

Activation of L-arginine transport (system y+) and nitric oxide synthase by elevated glucose and insulin in human endothelial cells.

scientific article

Activation of cannabinoid CB1 receptors induces glucose intolerance in rats.

scientific article published on 19 January 2006

Albumin elicits calcium signals from astrocytes in brain slices from neonatal rat cortex

scientific article published in June 1998

Antidiabetic actions of an estrogen receptor β selective agonist

scientific article

Author Correction: Molecular mechanisms involved in the non-monotonic effect of bisphenol-a on Ca2+ entry in mouse pancreatic β-cells.

scientific article

Bioluminescence imaging of nuclear calcium oscillations in intact pancreatic islets of Langerhans from the mouse.

scientific article published in August 2005

Bisphenol A Regulates Sodium Ramp Currents in Mouse Dorsal Root Ganglion Neurons and Increases Nociception

scientific article published on 16 July 2019

Bisphenol A exposure during pregnancy disrupts glucose homeostasis in mothers and adult male offspring

scientific article

Bisphenol-A acts as a potent estrogen via non-classical estrogen triggered pathways

scientific article published on December 31, 2011

Bisphenol-A disruption of the endocrine pancreas and blood glucose homeostasis.

scientific article published on 31 October 2007

Bisphenol-A treatment during pregnancy in mice: a new window of susceptibility for the development of diabetes in mothers later in life.

scientific article published in April 2015

Bovine subcommissural organ displays spontaneous and synchronous intracellular calcium oscillations

scientific article

CDK11 Promotes Cytokine-Induced Apoptosis in Pancreatic Beta Cells Independently of Glucose Concentration and Is Regulated by Inflammation in the NOD Mouse Model

publication published on 10 February 2021

Cannabinoid receptors regulate Ca(2+) signals and insulin secretion in pancreatic beta-cell.

scientific article published in February 2006

Cellular engineering and diabetes mellitus

scientific article published in September 2001

Chapel Hill bisphenol A expert panel consensus statement: integration of mechanisms, effects in animals and potential to impact human health at current levels of exposure

publication published in 2007

Cortistatin regulates glucose-induced electrical activity and insulin secretion in mouse pancreatic beta-cells

scientific article published on 24 September 2018

Cyclin D3 promotes pancreatic β-cell fitness and viability in a cell cycle-independent manner and is targeted in autoimmune diabetes.

scientific article

Disentangling the molecular mechanisms of action of endogenous and environmental estrogens.

scientific article

EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals

scientific article

Effects of Bisphenol A on ion channels: Experimental evidence and molecular mechanisms

scientific article published on 27 February 2016

Effects of bisphenol A treatment during pregnancy on kidney development in mice: a stereological and histopathological study.

scientific article published on 6 November 2017

Endocrine disruptors in the etiology of type 2 diabetes mellitus.

scientific article

Endocrine-disrupting chemicals and the regulation of energy balance

scientific article

Engineering pancreatic islets

Enhanced glucose-induced intracellular signaling promotes insulin hypersecretion: pancreatic beta-cell functional adaptations in a model of genetic obesity and prediabetes.

scientific article published on 26 January 2015

Estradiol modulates acetylcholine-induced Ca2+ signals in LHRH-releasing GT1-7 cells through a membrane binding site

scientific article published on November 2003

Estrogen and xenoestrogen actions on endocrine pancreas: from ion channel modulation to activation of nuclear function.

scientific article published in August 2004

Executive Summary to EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals.

scientific article

Experimental BPA Exposure and Glucose-Stimulated Insulin Response in Adult Men and Women

scientific article published on 12 September 2018

Exposure to bisphenol-A during pregnancy partially mimics the effects of a high-fat diet altering glucose homeostasis and gene expression in adult male mice

scientific article

Extranuclear-initiated estrogenic actions of endocrine disrupting chemicals: Is there toxicology beyond paracelsus?

scientific article published on 31 January 2017

Fetal and Adult Exposure to Bisphenol-A as a Contributing Factor in the Etiology of the Metabolic Syndrome

Flawed experimental design reveals the need for guidelines requiring appropriate positive controls in endocrine disruption research.

scientific article published on 17 February 2010

Functional and structural adaptations in the pancreatic α-cell and changes in glucagon signaling during protein malnutrition

scientific article published on 14 February 2012

GPR55 and the regulation of glucose homeostasis.

scientific article

Genistein affects adipose tissue deposition in a dose-dependent and gender-specific manner

scientific article

Glial cell responses to lipids bound to albumin in serum and plasma

scientific article

Glucagon-Like Peptide 1 Analogs and their Effects on Pancreatic Islets

scientific article published on 6 April 2016

Glucocorticoid treatment and endocrine pancreas function: implications for glucose homeostasis, insulin resistance and diabetes.

scientific article published on 30 September 2014

Glucocorticoids in vivo induce both insulin hypersecretion and enhanced glucose sensitivity of stimulus-secretion coupling in isolated rat islets

scientific article published on 30 October 2009

Glucose Induces Opposite Intracellular Ca2+Concentration Oscillatory Patterns in Identified α- and β-Cells Within Intact Human Islets of Langerhans

scientific article published on 01 September 2006

Glucose induces synchronous mitochondrial calcium oscillations in intact pancreatic islets

scientific article published on 11 May 2007

Impacts of food contact chemicals on human health: a consensus statement

scientific article published on 03 March 2020

In Vitro Assays to Identify Metabolism-Disrupting Chemicals with Diabetogenic Activity in a Human Pancreatic β-Cell Model

scientific article published on 01 May 2022

In utero exposure to bisphenol-A disrupts key elements of retinoid system in male mice offspring

scientific article published on 18 February 2019

Inhibition of connexin 36 hemichannels by glucose contributes to the stimulation of insulin secretion

scientific article published on 15 April 2014

Inhibitory effects of leptin on pancreatic alpha-cell function.

scientific article published on 28 April 2009

Insulin hypersecretion in islets from diet-induced hyperinsulinemic obese female mice is associated with several functional adaptations in individual β-cells

scientific article published on 18 July 2013

Involvement of ATP-sensitive potassium (K(ATP)) channels in the loss of beta-cell function induced by human islet amyloid polypeptide.

scientific article published on 7 October 2011

Involvement of the clock gene Rev-erb alpha in the regulation of glucagon secretion in pancreatic alpha-cells

scientific article

Lacking of estradiol reduces insulin exocytosis from pancreatic β-cells and increases hepatic insulin degradation.

scientific article

Leptin downregulates expression of the gene encoding glucagon in alphaTC1-9 cells and mouse islets

scientific journal article

Linking intermittent hypoxia, sympathetic response and metabolic disturbances

scientific article published on 09 July 2013

Lysophosphatidic acid induces Ca2+ mobilization and c-Myc expression in mouse embryonic stem cells via the phospholipase C pathway

scientific article published on 24 December 2008

Marine litter plastics and microplastics and their toxic chemicals components: the need for urgent preventive measures.

scientific article published on 18 April 2018

Maternal Exposure to Bisphenol-A During Pregnancy Increases Pancreatic β-Cell Growth During Early Life in Male Mice Offspring

scientific article

Metabolism Disrupting Chemicals and Metabolic Disorders

scientific article (publication date: 17 October 2016)

Mitochondria as target of endocrine-disrupting chemicals: implications for type 2 diabetes

scientific article published on 01 November 2018

Molecular mechanisms involved in the non-monotonic effect of bisphenol-a on ca2+ entry in mouse pancreatic β-cells.

scientific article published on 18 September 2017

Novel players in pancreatic islet signaling: from membrane receptors to nuclear channels.

scientific article published on February 2004

Nuclear KATP channels trigger nuclear Ca(2+) transients that modulate nuclear function

scientific article

Nutrient regulation of glucagon secretion: involvement in metabolism and diabetes.

scientific article published on 10 April 2014

Obesity: Fat from plastics? Linking bisphenol A exposure and obesity

scientific article

Oestradiol rapidly inhibits Ca2+ signals in ciliary neurons through classical oestrogen receptors in cytoplasm

scientific article published in October 2004

Oestrogen receptor β mediates the actions of bisphenol-A on ion channel expression in mouse pancreatic beta cells

scientific article published on 27 June 2019

Pancreatic alpha-cell dysfunction contributes to the disruption of glucose homeostasis and compensatory insulin hypersecretion in glucocorticoid-treated rats.

scientific article

Pancreatic alpha-cell mass in the early-onset and advanced stage of a mouse model of experimental autoimmune diabetes

scientific article published on 02 July 2019

Pancreatic alpha-cells from female mice undergo morphofunctional changes during compensatory adaptations of the endocrine pancreas to diet-induced obesity

scientific article

Pancreatic insulin content regulation by the estrogen receptor ER alpha

scientific article

Pancreatic islet cells: a model for calcium-dependent peptide release

scientific article published on 30 March 2010

Physiology of the pancreatic alpha-cell and glucagon secretion: role in glucose homeostasis and diabetes.

scientific article published on 31 July 2008

Plasma albumin is a potent trigger of calcium signals and DNA synthesis in astrocytes

scientific article

Polluted Pathways: Mechanisms of Metabolic Disruption by Endocrine Disrupting Chemicals

scientific article

Position paper: Rapid responses to steroids: current status and future prospects.

scientific article published on March 2010

Prenatal Exposure to BPA and Offspring Outcomes: The Diabesogenic Behavior of BPA

scientific article

Presence of functional cannabinoid receptors in human endocrine pancreas

scientific article

Rapid endocrine disruption: environmental estrogen actions triggered outside the nucleus.

scientific article published on 3 November 2006

Rapid insulinotropic action of low doses of bisphenol-A on mouse and human islets of Langerhans: role of estrogen receptor β

scientific article

Rapid non-genomic regulation of Ca2+ signals and insulin secretion by PPAR alpha ligands in mouse pancreatic islets of Langerhans

scientific article published on 18 November 2008

Rapid regulation of K(ATP) channel activity by 17{beta}-estradiol in pancreatic {beta}-cells involves the estrogen receptor {beta} and the atrial natriuretic peptide receptor.

scientific article

Rapid regulation of pancreatic alpha- and beta- cell signalling systems by estrogens

scientific article published in March 2008

Rapid responses to steroid hormones. Preface

scientific article published on 10 February 2010

Reduced insulin secretion in protein malnourished mice is associated with multiple changes in the beta-cell stimulus-secretion coupling.

scientific article published on 16 June 2010

Regulation of K(ATP) channel by 17β-estradiol in pancreatic β-cells.

scientific article published on 04 April 2011

Role of ERβ and GPR30 in the endocrine pancreas: A matter of estrogen dose

scientific article published on 28 January 2012

Role of cannabinoid CB2 receptors in glucose homeostasis in rats

scientific article published on 20 April 2007

Role of estrogen receptors alpha, beta and GPER1/GPR30 in pancreatic beta-cells.

scientific article published on January 2011

Role of iduronate-2-sulfatase in glucose-stimulated insulin secretion by activation of exocytosis.

scientific article published on 14 July 2009

Role of leptin in the pancreatic β-cell: effects and signaling pathways.

scientific article published on 29 May 2012

Salicylates increase insulin secretion in healthy obese subjects

scientific article published on 6 May 2008

Short-term treatment with bisphenol-A leads to metabolic abnormalities in adult male mice

scientific article

Taurine supplementation ameliorates glucose homeostasis, prevents insulin and glucagon hypersecretion, and controls β, α, and δ-cell masses in genetic obese mice.

scientific article published on 05 May 2015

The F-actin cortical network is a major factor influencing the organization of the secretory machinery in chromaffin cells

scientific article published on 08 February 2011

The GOLIATH Project: Towards an Internationally Harmonised Approach for Testing Metabolism Disrupting Compounds

scientific article published on 14 May 2020

The atrial natriuretic peptide and guanylyl cyclase-A system modulates pancreatic beta-cell function.

scientific article published on 16 June 2010

The bile acid TUDCA increases glucose-induced insulin secretion via the cAMP/PKA pathway in pancreatic beta cells

scientific article

The clock gene Rev-erbα regulates pancreatic β-cell function: modulation by leptin and high-fat diet

scientific journal article

The estrogenic effect of bisphenol A disrupts pancreatic beta-cell function in vivo and induces insulin resistance

scientific article

The pancreatic beta-cell as a target of estrogens and xenoestrogens: Implications for blood glucose homeostasis and diabetes.

scientific article published on 09 March 2009

The plasma membrane estrogen receptor: nuclear or unclear?

scientific article published on 01 December 2001

The relationship between glucose-induced K+ATP channel closure and the rise in [Ca2+]i in single mouse pancreatic beta-cells

article by M Valdeolmillos et al published 1 September 1992 in Journal of Physiology

The role of estrogen receptors in the control of energy and glucose homeostasis.

scientific article published on 27 December 2007

The role of the pancreatic endocannabinoid system in glucose metabolism.

scientific article published on February 2009

Update on Activities in Endocrine Disruptor Research and Policy

scientific article published on 01 July 2019

Uppsala Consensus Statement on Environmental Contaminants and the Global Obesity Epidemic

scientific article (publication date: May 2016)

Why public health agencies cannot depend on good laboratory practices as a criterion for selecting data: the case of bisphenol A

scientific article

Widespread synchronous [Ca2+]i oscillations due to bursting electrical activity in single pancreatic islets

scientific article published on 01 May 1991