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List of works by Joost Smolders

A low vitamin D status at diagnosis is associated with an early conversion to secondary progressive multiple sclerosis.

scientific article

An Update on Vitamin D and Disease Activity in Multiple Sclerosis

scientific article published on 01 December 2019

Association of vitamin D metabolite levels with relapse rate and disability in multiple sclerosis

scientific article published on 24 July 2008

Association study on two vitamin D receptor gene polymorphisms and vitamin D metabolites in multiple sclerosis

scientific article published in September 2009

B and T Cells Driving Multiple Sclerosis: Identity, Mechanisms and Potential Triggers

scientific article published on 08 May 2020

Brain-homing CD4+ T cells display glucocorticoid-resistant features in MS

scientific article published on 09 October 2020

Characteristics of differentiated CD8(+) and CD4 (+) T cells present in the human brain.

scientific article

Circulating vitamin D binding protein levels are not associated with relapses or with vitamin D status in multiple sclerosis

scientific article

Comment on the article by Allen et al. ‘A pilot study of the immunological effects of high-dose vitamin D in healthy volunteers’

scientific article published on August 20, 2012

Complementary and alternative medicine in alopecia areata.

scientific article published on January 2010

Control of T cell activation by vitamin D

scientific article published on 01 January 2011

Correlation of different cellular assays to analyze T cell-related cytokine profiles in vitamin D3-supplemented patients with multiple sclerosis

scientific article published on 11 December 2018

Effect of vitamin D(3) supplementation on peripheral B cell differentiation and isotype switching in patients with multiple sclerosis

scientific article

Effects of vitamin D on the peripheral adaptive immune system: a review

scientific article published on 18 May 2011

Efficacy of vitamin D3 as add-on therapy in patients with relapsing-remitting multiple sclerosis receiving subcutaneous interferon β-1a: a Phase II, multicenter, double-blind, randomized, placebo-controlled trial

scientific article published on 28 May 2011

Exploring the effect of vitamin D3 supplementation on the anti-EBV antibody response in relapsing-remitting multiple sclerosis.

scientific article

Expression of vitamin D receptor and metabolizing enzymes in multiple sclerosis-affected brain tissue

scientific article published in February 2013

Fatigue and heat sensitivity in patients with multiple sclerosis.

scientific article published on 8 March 2012

Fluctuations of MS births and UV-light exposure.

scientific article

Fraction of IL-10+ and IL-17+ CD8 T cells is increased in MS patients in remission and during a relapse, but is not influenced by immune modulators

scientific article published on 19 March 2013

GM-CSF production by CD4+ T cells in MS patients: regulation by regulatory T cells and vitamin D.

scientific article

Human T-bet+ B cell development is associated with BTK activity and suppressed by evobrutinib

scientific article published in 2022

Hypercalcaemia rather than high dose vitamin D3 supplements could exacerbate multiple sclerosis

scientific article published on 01 December 2019

Immune regulatory effects of high dose vitamin D3 supplementation in a randomized controlled trial in relapsing remitting multiple sclerosis patients receiving IFNβ; the SOLARIUM study

scientific article published on 3 October 2016

Immunomodulation by vitamin D in multiple sclerosis: More than IL-17.

scientific article published on 27 January 2016

Increased inflammasome related gene expression profile in PBMC may facilitate T helper 17 cell induction in multiple sclerosis.

scientific article published on February 2015

Intracellular IL-10 detection in T cells by flowcytometry: the use of protein transport inhibitors revisited

scientific article published on 29 April 2012

Isolation of primary microglia from the human post-mortem brain: effects of ante- and post-mortem variables

scientific article published on 17 February 2017

Microglia in normal appearing white matter of multiple sclerosis are alerted but immunosuppressed

scientific article

Mycoplasma Pneumoniae and Antibodies against Galactocerebroside in a 9-Year-Old Boy with Encephalitis

scientific article published on 26 November 2018

Naive B cells in neuromyelitis optica spectrum disorders: impact of steroid use and relapses

scientific article published on 16 November 2020

Natural killer cells in multiple sclerosis: A review

scientific article published on 27 February 2020

Network of nuclear receptor ligands in multiple sclerosis: Common pathways and interactions of sex-steroids, corticosteroids and vitamin D3-derived molecules

scientific article

On the ethics of not supplementing low 25-hydroxyvitamin D levels in a controlled study in relapsing remitting multiple sclerosis

scientific article published on 9 June 2017

Pediatric MS patients with a primary progressive-like disease may still have relevant inflammatory activity and may benefit from regular MS treatment

scientific article published on 14 May 2020

Perivascular tissue resident memory T cells as therapeutic target in multiple sclerosis

scientific article published on 30 May 2020

Phenotyping primary human microglia: tight regulation of LPS responsiveness.

scientific article published on 27 June 2012

Post-mortem multiple sclerosis lesion pathology is influenced by single nucleotide polymorphisms

scientific article published on 23 July 2019

Prognostic value of NK cell/ T cell ratios for disease activity in multiple sclerosis

scientific article published on 16 December 2020

Randomized trial of daily high-dose vitamin D3 in patients with RRMS receiving subcutaneous interferon β-1a

scientific article published on 08 October 2019

Reduction in IL-10 producing B cells (Breg) in multiple sclerosis is accompanied by a reduced naïve/memory Breg ratio during a relapse but not in remission

scientific article published on 21 September 2011

Regulatory T cell function correlates with serum 25-hydroxyvitamin D, but not with 1,25-dihydroxyvitamin D, parathyroid hormone and calcium levels in patients with relapsing remitting multiple sclerosis

scientific article published on 6 March 2010

Reply: Tissue-resident CD8+ memory T cells in multiple sclerosis

scientific article published on 13 December 2020

Safety and T cell modulating effects of high dose vitamin D3 supplementation in multiple sclerosis

scientific article (publication date: 13 December 2010)

Stress-Axis Regulation by Vitamin D3 in Multiple Sclerosis.

scientific article published on 26 April 2018

Th17 expansion in MS patients is counterbalanced by an expanded CD39+ regulatory T cell population during remission but not during relapse

scientific article published on 26 October 2011

The Diagnostic Sensitivity for Ulnar Neuropathy at the Elbow Is Not Increased by Addition of Needle EMG of ADM and FDI When Nerve Conduction Studies Are Normal

article

The Engagement Between Vitamin D and the Immune System: Is Consolidation by a Marriage to Be Expected?

scientific article

The association of Epstein-Barr virus infection with CXCR3+ B-cell development in multiple sclerosis impact of immunotherapies

scientific article published on 05 November 2020

The multiple sclerosis susceptibility genes TAGAP and IL2RA are regulated by vitamin D in CD4+ T cells.

scientific article

The relevance of vitamin D receptor gene polymorphisms for vitamin D research in multiple sclerosis

scientific article published on 11 February 2009

Tissue-resident memory T cells invade the brain parenchyma in multiple sclerosis white matter lesions

scientific article published on 13 May 2020

Tissue-resident memory T cells populate the human brain

scientific article published in Nature Communications

Vitamin D Status Does Not Affect Disability Progression of Patients with Multiple Sclerosis over Three Year Follow-Up

scientific article

Vitamin D as a T-cell Modulator in Multiple Sclerosis

scientific article published on January 1, 2011

Vitamin D as an immune modulator in multiple sclerosis, a review

scientific article published on 04 January 2008

Vitamin D in multiple sclerosis: implications for assessment and treatment

scientific article published on September 2012

Vitamin D in the healthy and inflamed central nervous system: access and function

scientific article published on 23 August 2011

Vitamin D status in patients with MS is negatively correlated with depression, but not with fatigue

scientific article published on 29 September 2010

Vitamin D status is negatively correlated with retinal nerve fiber layer thickness in relapsing-remitting MS patients without acute optic neuritis

scientific article published on 14 June 2016

Vitamin D status is positively correlated with regulatory T cell function in patients with multiple sclerosis

scientific article

Vitamin D supplementation and antibodies against the Epstein-Barr virus in multiple sclerosis patients

scientific article

Vitamin D-related gene expression profiles in immune cells of patients with relapsing remitting multiple sclerosis

scientific article published on 20 April 2011

Vitamin D3 supplementation and neurofilament light chain in multiple sclerosis

scientific article published on 26 November 2019

Vitamin D3 supplementation and the IL-2/IL-2R pathway in multiple sclerosis: Attenuation of progressive disturbances?

scientific article

Vitamin D3 supplementation in multiple sclerosis: Symptoms and biomarkers of depression

scientific article published on 19 April 2017

Vitamin d and multiple sclerosis: correlation, causality, and controversy

scientific article published on 05 October 2010

White matter lesions in multiple sclerosis are enriched for CD20dim CD8+ tissue-resident memory T cells

scientific article published on 19 September 2020