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List of works by Timothy G. Buchman

A New Safety Event Reporting System Improves Physician Reporting in the Surgical Intensive Care Unit

scientific article published on 01 June 2006

AGE DISPROPORTIONATELY INCREASES SEPSIS-INDUCED APOPTOSIS IN THE SPLEEN AND GUT EPITHELIUM

article

Antibiotics improve survival and alter the inflammatory profile in a murine model of sepsis from Pseudomonas aeruginosa pneumonia

scientific article published in May 2003

Apoptosis in lymphoid and parenchymal cells during sepsis: findings in normal and T- and B-cell-deficient mice

scientific article published in August 1997

Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction

scientific article published on 01 July 1999

Association between lymphotoxin-alpha (tumor necrosis factor-beta) intron polymorphism and predisposition to severe sepsis is modified by gender and age.

scientific article published on January 2010

Autonomic information flow improves prognostic value of heart rate patterns after abdominal aortic surgery

scientific article published on 18 December 2007

Biologically variable ventilation improves gas exchange and respiratory mechanics in a model of severe bronchospasm

scientific article published in July 2007

Biomedical Complexity and Error

scientific article published on 30 April 2011

Cancer causes increased mortality and is associated with altered apoptosis in murine sepsis.

scientific article

Cardiovascular variability as a measure of inflammation*.

scientific article published in August 2014

Clinical molecular genetics and critical care medicine

article

Coagulation inhibitors in the treatment of sepsis ⬇️

scientific article published on January 1, 2002

Comparing the information seeking strategies of residents, nurse practitioners, and physician assistants in critical care settings

scientific article published on 11 March 2014

Comparison of Intravenous/Oral Ciprofloxacin Plus Metronidazole Versus Piperacillin/Tazobactam in the Treatment of Complicated Intraabdominal Infections

article

Comparison of circuit patency and exchange rates between 2 different continuous renal replacement therapy machines

scientific article published on 25 November 2013

Critical care: On target

scientific article published on 01 April 2003

Cytochrome P450 polymorphisms are associated with reduced warfarin dose

scientific article published on 01 August 2000

Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms

scientific article

Early antibiotic administration but not antibody therapy directed against IL-6 improves survival in septic mice predicted to die on basis of high IL-6 levels.

scientific article

Effect of chlorhexidine/silver sulfadiazine-impregnated central venous catheters in an intensive care unit with a low blood stream infection rate after implementation of an educational program: a before-after trial.

scientific article

Effects of aging on the immunopathologic response to sepsis.

scientific article published on March 2009

Efficacy and safety of an insulin infusion protocol in a surgical ICU.

scientific article published on 18 November 2005

Endothelial cell apoptosis is accelerated by inorganic iron and heat via an oxygen radical dependent mechanism

scientific article published on 01 August 1997

Energy deficit and length of hospital stay can be reduced by a two-step quality improvement of nutrition therapy

scientific article published on 01 February 2012

Epidermal growth factor treatment decreases mortality and is associated with improved gut integrity in sepsis.

scientific article published on July 2008

Ethical considerations in the collection of genetic data from critically ill patients: what do published studies reveal about potential directions for empirical ethics research?

scientific article

Evaluation of the Applicability, Efficacy, and Safety of a Thromboembolic Event Prophylaxis Guideline Designed for Quality Improvement of the Traumatically Injured Patient

scientific article published on 01 April 2005

Examination of non-clinical factors affecting tracheostomy practice in an academic surgical intensive care unit*

scientific article published on 01 December 2009

Experimental human endotoxemia increases cardiac regularity: results from a prospective, randomized, crossover trial

scientific article published on July 1996

Extra credit*

scientific article published on 01 March 2012

Families' perceptions of surgical intensive care

scientific article published on June 2003

Feasibility and economic impact of dedicated hospice inpatient units for terminally ill ICU patients.

scientific article published on May 2014

Fractals in Clinical Hemodynamics

scientific article published on 01 October 2012

From data patterns to biological mechanism in critical illness: the role of engineering

scientific article

Generating Signals with Multiscale Time Irreversibility: The Asymmetric Weierstrass Function

scientific article published on March 2011

Genetic research and testing in critical care: surrogates' perspective

scientific article

Genetic susceptibility to hemorrhagic complications during warfarin therapy

scientific article

Guidelines for the selection of anti-infective agents for complicated intra-abdominal infections.

scientific article published on 25 September 2003

Half empty or half full?*

scientific article published on 01 August 2010

Hepatic heat shock and acute-phase gene expression are induced simultaneously after celiotomy in the anesthetized pig.

scientific article published in October 1995

High-dose exogenous iron following cecal ligation and puncture increases mortality rate in mice and is associated with an increase in gut epithelial and splenic apoptosis

scientific article published in May 2004

High-frequency oscillatory ventilation for acute respiratory distress syndrome in adults: a randomized, controlled trial

scientific article published in September 2002

Improved extubation rates and earlier liberation from mechanical ventilation with implementation of a daily spontaneous-breathing trial protocol

scientific article published on 11 December 2007

In vivo, in vitro, in silico. . .*

scientific article published on 01 October 2004

In-hospital mortality after cardiac surgery: patient characteristics, timing, and association with postoperative length of intensive care unit and hospital stay

scientific article published on 21 December 2013

Inducible nitric oxide synthase (iNOS) gene deficiency increases the mortality of sepsis in mice

scientific article published in August 1999

Induction of translational thermotolerance in liver of thermally stressed rats

scientific article published on 01 December 1993

Informal Contracts, Shared Decision Making, and the Covenant of Care* ⬇️

scientific article published on January 1, 2013

Interleukin-1 receptor antagonist as therapy for inflammatory disorders ⬇️

scientific article published on March 1, 2001

Intestine-specific overexpression of IL-10 improves survival in polymicrobial sepsis.

scientific article published on April 2008

Invited commentary: experience matters

scientific article published on December 2008

Iron dysregulation combined with aging prevents sepsis-induced apoptosis

scientific article

Mammalian liver contains an activity which mimics bacterial chloramphenicol acetyltransferase

scientific article published on November 1990

Mathematical estimates of recovery after loss of activity: II. Long-range connectivity facilitates rapid functional recovery

scientific article published in February 2008

Mathematical estimation of recovery after loss of activity: I. Renal failure

scientific article published in July 2007

Modules, modularity and adaptation

scientific article published on 06 May 2011

Molecular Diagnostics in Sepsis: From Bedside to Bench

scientific article published on 11 September 2006

Morbidity and timing of colostomy closure in trauma patients

scientific article published on August 1993

Myocardial infarction as a complication of injury11No competing interests declared

scientific article published on 01 June 2000

Myocardial transcriptional profiles in a murine model of sepsis: evidence for the importance of age.

scientific article

National estimates of hospitalization charges for the acute care of traumatic brain injuries

scientific article published on November 2003

Neutrophil depletion causes a fatal defect in murine pulmonary Staphylococcus aureus clearance.

scientific article published on 13 March 2008

Nitric oxide inhibits stress-induced endothelial cell apoptosis

scientific article published on 01 September 1998

Nonlinear dynamics, complex systems, and the pathobiology of critical illness.

scientific article published in October 2004

Novel representation of physiologic states during critical illness and recovery

scientific article published on 4 March 2010

Patient-care time allocation by nurse practitioners and physician assistants in the intensive care unit ⬇️

scientific article published on February 15, 2012

Physiologic Stability and Physiologic State

scientific article published on 01 October 1996

Physiological noise versus white noise to drive a variable ventilator in a porcine model of lung injury

scientific article

Postoperative abdominal complications in cardiopulmonary bypass patients: A case-controlled study

article

Postreperfusion cardiac arrest and resuscitation during orthotopic liver transplantation: dynamic visualization and analysis of physiologic recordings

scientific article published on January 2012

Predicting clinical physiology: a Markov chain model of heart rate recovery after spontaneous breathing trials in mechanically ventilated patients

scientific article

Prediction of heart rate response to conclusion of the spontaneous breathing trial by fluctuation dissipation theory

scientific article published on 30 January 2013

Prescribing patterns of hydrocortisone in septic shock: a single-center experience of how surviving sepsis guidelines are interpreted and translated into bedside practice

scientific article published on October 2013

Proceedings from the Montebello Round Table Discussion. Second annual conference on Complexity and Variability discusses research that brings innovation to the bedside

scientific article published in June 2011

Quantifying resilience of humans and other animals

article published in the Proceedings of the National Academy of Sciences of the United States of America

RNAi.

scientific article

Recovery at the edge of error: debunking the myth of the infallible expert

scientific article published on October 2010

Reduced red blood cell transfusion in cardiothoracic surgery after implementation of a novel clinical decision support tool

scientific article published on 25 June 2014

Relationship between tracheostomy timing and duration of mechanical ventilation in critically ill patients

scientific article published in November 2005

Sepsis from Pseudomonas aeruginosa pneumonia decreases intestinal proliferation and induces gut epithelial cell cycle arrest*

scientific article published on 01 June 2003

Sepsis through the eyes of an engineer -- why treatments have succeeded and failed

scientific article published on January 2012

Sequence makes a difference: paradoxical effects of stress in vivo

scientific article published in September 2004

Shock Supports the Use of Animal Research Reporting Guidelines

scientific article published on 01 July 2012

Slowing Down of Recovery as Generic Risk Marker for Acute Severity Transitions in Chronic Diseases

scientific article published on 12 January 2016

Social Norms and Global Environmental Challenges: The Complex Interaction of Behaviors, Values, and Policy

scientific article

Some like it hot

scientific article published on 01 October 1997

Streptococcus pneumoniae and Pseudomonas aeruginosa pneumonia induce distinct host responses

scientific article

Surgeons and their patients near the end of life

scientific article

Surgeons, intensivists, and the covenant of care: administrative models and values affecting care at the end of life--Updated

scientific article published in May 2003

Targeted temperature management in critical care: a report and recommendations from five professional societies

scientific article published on May 2011

Template-directed dye-terminator incorporation with fluorescence polarization detection for analysis of single nucleotide polymorphisms associated with cardiovascular and thromboembolic disease

scientific article published on 01 January 2003

The Price of a Miracle

scientific article published on 01 January 2012

The digital patient: predicting physiologic dynamics with mathematical models

scientific article published in March 2009

The frequency and effects of cytochrome P450 (CYP) 2C9 polymorphisms in patients receiving warfarin

scientific article published in March 2002

The heat shock paradox: does NF-κB determine cell fate?

scientific article published on 01 January 2001

The impact of a simple, low-cost oral care protocol on ventilator-associated pneumonia rates in a surgical intensive care unit

scientific article published on January 2009

The impact of bedside behavior on catheter-related bacteremia in the intensive care unit.

scientific article published in February 2004

The turn team: a novel strategy for reducing pressure ulcers in the surgical intensive care unit

scientific article published on 11 January 2013

Toward optimal display of physiologic status in critical care: I. Recreating bedside displays from archived physiologic data ⬇️

scientific article published on September 1, 2010

Tracheostomy protocol: experience with development and potential utility

scientific article published in June 2008

Transmission of herpes-simplex virus type 1 in a nursery for the newborn. Identification of viral isolates by D.N.A. "fingerprinting".

scientific article

Treatment of hypophosphatemia using a protocol based on patient weight and serum phosphorus level in a surgical intensive care unit.

scientific article published in February 2004

Tumor necrosis factor -308 polymorphism (rs1800629) is associated with mortality and ventilator duration in 1057 Caucasian patients

scientific article

Uncoupling of biological oscillators: a complementary hypothesis concerning the pathogenesis of multiple organ dysfunction syndrome

scientific article published on July 1996

Using "off-the-shelf" tools for terabyte-scale waveform recording in intensive care: computer system design, database description and lessons learned

scientific article

Who should manage the dying patient?: Rescue, shame, and the surgical ICU dilemma

scientific article published in May 2002

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