Search filters

List of works by Clifford J Bailey

A double-blind randomized study comparing the effects of continuing or not continuing rosiglitazone + metformin therapy when starting insulin therapy in people with Type 2 diabetes.

scientific article

A new experimental protocol for preferential differentiation of mouse embryonic stem cells into insulin-producing cells.

scientific article published in January 2008

A novel, long-acting agonist of glucose-dependent insulinotropic polypeptide suitable for once-daily administration in type 2 diabetes.

scientific article

Acute and long-term effects of metformin on the function and insulin secretory responsiveness of clonal β-cells

scientific article published on December 2010

Acute and long-term effects of peroxisome proliferator-activated receptor-γ activation on the function and insulin secretory responsiveness of clonal beta-cells

scientific article published on 16 December 2010

Age-associated changes in long-chain fatty acid profile during healthy aging promote pro-inflammatory monocyte polarization via PPARγ.

scientific article

Ageing, adipose tissue, fatty acids and inflammation

scientific article

Antagonistic effects of two novel GIP analogs, (Hyp3)GIP and (Hyp3)GIPLys16PAL, on the biological actions of GIP and longer-term effects in diabetic ob/ob mice.

scientific article published on 13 February 2007

Antidiabetic potential of two novel fatty acid derivatised, N-terminally modified analogues of glucose-dependent insulinotropic polypeptide (GIP): N-AcGIP(LysPAL16) and N-AcGIP(LysPAL37).

scientific article

Avandamet: combined metformin-rosiglitazone treatment for insulin resistance in type 2 diabetes.

scientific article

Bromocriptine: old drug, new formulation and new indication ⬇️

scientific article published on December 1, 2010

Cardio-diabetes alliances

scientific article published on 01 March 2007

Cardiovascular protection in type 2 diabetes: Insights from recent outcome trials

scientific article published on 07 September 2018

Changes in gene expression and morphology of mouse embryonic stem cells on differentiation into insulin-producing cells in vitro and in vivo.

scientific article published in July 2009

Choosing GLP-1 receptor agonists or SGLT-2 inhibitors by cardiorenal risk

scientific article published on 13 December 2019

Could FFAR1 assist insulin secretion in type 2 diabetes?

scientific article published on 27 February 2012

Dapagliflozin in patients with type 2 diabetes mellitus: A pooled analysis of safety data from phase IIb/III clinical trials

scientific article published on 26 September 2017

Dapagliflozin monotherapy in drug-naïve patients with diabetes: a randomized-controlled trial of low-dose range

scientific article published on 24 July 2012

Dapagliflozin therapy for type 2 diabetes in primary care: Changes in HbA1c, weight and blood pressure over 2 years follow-up

scientific article published on 02 June 2017

Degradation, insulin secretion, and antihyperglycemic actions of two palmitate-derivitized N-terminal pyroglutamyl analogues of glucose-dependent insulinotropic polypeptide.

scientific article

Degradation, receptor binding, insulin secreting and antihyperglycaemic actions of palmitate-derivatised native and Ala8-substituted GLP-1 analogues.

scientific article

Delta opioid receptors mediate glucose uptake in skeletal muscles of lean and obese-diabetic (ob/ob) mice.

scientific article published on December 2001

Diabetes: insulin plus metformin for T2DM--are there benefits?

scientific article published on 26 June 2012

Dipeptidyl peptidase IV (DPP IV) inhibitors: A newly emerging drug class for the treatment of type 2 diabetes.

scientific article

Drugs on the horizon for diabesity.

scientific article

Durability of glycaemic control with dapagliflozin, an SGLT2 inhibitor, compared with saxagliptin, a DPP4 inhibitor, in patients with inadequately controlled type 2 diabetes

scientific article published on 26 August 2019

Earlier intervention in type 2 diabetes: the case for achieving early and sustained glycaemic control.

scientific article

Early and intensive treatment: Glycaemic control in type 2 diabetes

scientific article published on 01 December 2006

Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin: a randomised, double-blind, placebo-controlled trial

scientific article published on June 2010

Effects of metformin on BRIN-BD11 beta-cell insulin secretory desensitization induced by prolonged exposure to sulphonylureas

scientific article published on December 2010

Efficacy and safety of dapagliflozin monotherapy in people with Type 2 diabetes: a randomized double-blind placebo-controlled 102-week trial

scientific article published on 22 November 2014

European Medicines Agency: Approval of new glucose-lowering medicines for type 2 diabetes

scientific article published on 05 June 2018

FDA guidance on cardiovascular risk of antidiabetic therapies: One decade later

scientific article published on 15 March 2019

Fatty acid derivatised analogues of glucose-dependent insulinotropic polypeptide with improved antihyperglycaemic and insulinotropic properties.

scientific article

Fenofibrate and cardiovascular risk: a synopsis and commentary on (FIELD).

scientific article published in February 2006

Fixed-dose single tablet antidiabetic combinations

scientific article

Future glucose-lowering drugs for type 2 diabetes.

scientific article

GIP analogues and the treatment of obesity-diabetes

scientific article published on 19 November 2019

GIP(Lys16PAL) and GIP(Lys37PAL): novel long-acting acylated analogues of glucose-dependent insulinotropic polypeptide with improved antidiabetic potential.

scientific article

Gaps and barriers in the control of blood glucose in people with type 2 diabetes.

scientific article

Glucosamine-induced insulin resistance in L6 muscle cells

scientific article published on July 2004

Glucose-lowering therapies in type 2 diabetes: Opportunities and challenges for peptides

scientific article published in February 2018

Glycated Hemoglobin, Body Weight and Blood Pressure in Type 2 Diabetes Patients Initiating Dapagliflozin Treatment in Primary Care: A Retrospective Study

scientific article published on September 2016

Hemostatic abnormalities associated with obesity and the metabolic syndrome.

scientific article published in May 2005

Human amniotic epithelial cells induce localized cell-mediated immune privilege in vitro: implications for pancreatic islet transplantation

scientific article published on 30 September 2010

Human islet isolation: semi-automated and manual methods.

scientific article published on March 2007

In vivo and ex vivo regulation of visfatin production by leptin in human and murine adipose tissue: role of mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling pathways

scientific article

Increased neuropeptide-Y messenger ribonucleic acid (mRNA) and decreased neurotensin mRNA in the hypothalamus of the obese (ob/ob) mouse.

scientific article

Inhaled insulin: new formulation, new trial

scientific article published on 01 June 2010

Insulin degludec: a new ultra-longacting insulin

scientific article published on 01 April 2012

Insulin resistance: Impact on therapeutic developments in diabetes

scientific article published on 01 March 2019

Learning from tesaglitazar

scientific article published in September 2007

Leptin prevents the fall in plasma osteocalcin during starvation in male mice.

scientific article

Lipoic acid increases glucose uptake by skeletal muscles of obese-diabetic ob/ob mice.

scientific article published on January 2002

Low gravity rotational culture and the integration of immunomodulatory stem cells reduce human islet allo-reactivity

scientific article published on 05 December 2014

Lys9 for Glu9 substitution in glucagon-like peptide-1(7-36)amide confers dipeptidylpeptidase IV resistance with cellular and metabolic actions similar to those of established antagonists glucagon-like peptide-1(9-36)amide and exendin (9-39).

scientific article published in February 2004

Macrophage polarisation by fatty acids is PPARgamma-dependent

scientific article published in October 2014

Management of type 2 diabetes: new and future developments in treatment

scientific article published on 24 June 2011

Metabolic memory effect of the saturated fatty acid, palmitate, in monocytes

scientific article

Metformin and the gastrointestinal tract

scientific article

Metformin and the intestine

scientific article published on 5 June 2008

Metformin extended-release versus immediate-release: An international, randomized, double-blind, head-to-head trial in pharmacotherapy-naïve patients with type 2 diabetes

scientific article

Metformin in patients with type 2 diabetes and kidney disease: a systematic review

scientific article published on December 2014

Metformin in women with type 2 diabetes in pregnancy

scientific article published on 01 October 2020

Metformin: a multitasking medication

scientific article

Metformin: effects on micro and macrovascular complications in type 2 diabetes.

scientific article published on 21 February 2008

Metformin: historical overview

scientific article published on 3 August 2017

N-terminal His(7)-modification of glucagon-like peptide-1(7-36) amide generates dipeptidyl peptidase IV-stable analogues with potent antihyperglycaemic activity.

scientific article published on March 2004

New drugs for type 2 diabetes mellitus: what is their place in therapy?

scientific article published on January 2008

New therapies for diabesity.

scientific article published on October 2009

Novel dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1(7-36)amide have preserved biological activities in vitro conferring improved glucose-lowering action in vivo.

scientific article published on December 2003

Novel glucagon-like peptide-1 (GLP-1) analog (Val8)GLP-1 results in significant improvements of glucose tolerance and pancreatic beta-cell function after 3-week daily administration in obese diabetic (ob/ob) mice.

scientific article published on 28 April 2006

Oleate protects against palmitate-induced insulin resistance in L6 myotubes.

scientific article published on 22 July 2009

Oral Antidiabetic Agents

scientific article

Palmitate promotes monocyte atherogenicity via de novo ceramide synthesis.

scientific article published on 26 May 2012

Paradoxical decrease in HDL-cholesterol and apolipoprotein A1 with simvastatin and atorvastatin in a patient with type 2 diabetes

scientific article

Patient adherence to medication requirements for therapy of type 2 diabetes.

scientific article published on March 2011

Pharmacology and therapeutic implications of current drugs for type 2 diabetes mellitus

scientific article

Phenotypic characteristics and risk factors in a multi-ethnic cohort of young adults with type 2 diabetes

scientific article published on 05 August 2019

Plasma irisin is elevated in type 2 diabetes and is associated with increased E-selectin levels

scientific article published on 9 November 2017

Plasma irisin levels predict telomere length in healthy adults

scientific article

Pre-transplant signal induction for vascularisation in human islets

scientific article published on 22 September 2013

Pronounced reduction of postprandial glucagon by lixisenatide: a meta-analysis of randomized clinical trials

scientific article published on 11 April 2014

Recent advances in antidiabetic drug therapies targeting the enteroinsular axis.

scientific article published on February 2009

Reduced postprandial proinsulinaemia and 32-33 split proinsulinaemia after a mixed meal in type 2 diabetic patients following sensitization to insulin with pioglitazone

scientific article published on 2 November 2007

Renal glucose reabsorption inhibitors to treat diabetes

scientific article published on 04 January 2011

Reports of Lactic Acidosis Attributed to Metformin, 2015-2018

scientific article published on 09 October 2019

Response to Comment on Flory et al. Reports of Lactic Acidosis Attributed to Metformin, 2015-2018. Diabetes Care 2020;43:244-246

scientific article published on 01 October 2020

Response to comment on Home et al. Insulin therapy in people with type 2 diabetes: opportunities and challenges? Diabetes care 2014;37:1499-1508.

scientific article published on November 2014

Rosiglitazone/metformin fixed-dose combination compared with uptitrated metformin alone in type 2 diabetes mellitus: a 24-week, multicenter, randomized, double-blind, parallel-group study.

scientific article published in October 2005

Rotational co-culture of clonal β-cells with endothelial cells: effect of PPAR-γ agonism in vitro on insulin and VEGF secretion

scientific article published on July 2011

Rotational culture and integration with amniotic stem cells reduce porcine islet immunoreactivity in vitro and slow xeno-rejection in a murine model of islet transplantation

scientific article published on 08 April 2019

SGLT inhibitors in management of diabetes

scientific article published on 13 August 2013

Safety of antidiabetes medications: An update

scientific article published on 02 May 2015

Sibutramine metabolites increase glucose transport by cultured rat muscle cells

scientific article published on 01 April 2001

Sites of metformin-stimulated glucose metabolism

scientific article published on 01 June 1990

Sustained insulin secretory response in human islets co-cultured with pancreatic duct-derived epithelial cells within a rotational cell culture system

scientific article published on 8 January 2009

Systematic screening of compressed ODT excipients: cellulosic versus non-cellulosic

scientific article published on 01 January 2014

Tailoring treatment to the individual in type 2 diabetes practical guidance from the Global Partnership for Effective Diabetes Management

scientific article

The Current Drug Treatment Landscape for Diabetes and Perspectives for the Future

scientific article published on 23 June 2015

The challenge of managing coexistent type 2 diabetes and obesity

scientific article published on 13 April 2011

The efficacy and safety of imeglimin as add-on therapy in patients with type 2 diabetes inadequately controlled with sitagliptin monotherapy

scientific article published on 10 April 2014

The future of new drugs for diabetes management

scientific article published on 19 July 2019

The interdisciplinary team in type 2 diabetes management: Challenges and best practice solutions from real-world scenarios.

scientific article published on 9 December 2016

The primary amine metabolite of sibutramine stimulates lipolysis in adipocytes isolated from lean and obese mice and in isolated human adipocytes.

scientific article published in November 2006

The sibutramine metabolite M2 improves muscle glucose uptake and reduces hepatic glucose output: preliminary data

scientific article

The therapeutic use of lipoic acid in diabetes: a current perspective.

scientific article published on September 2001

Treating T2DM and obesity with bariatric surgery and GLP1 agents

scientific article published on 01 September 2019

Treating insulin resistance in type 2 diabetes with metformin and thiazolidinediones.

scientific article

Treating insulin resistance: future prospects.

scientific article published on March 2007

Treatment of type 2 diabetes: future approaches

scientific article published on 01 June 2018

Type 2 diabetes in adolescents and young adults

scientific article published on 25 August 2017

Type 2 diabetes: assessing the relative risks and benefits of glucose-lowering medications.

scientific article published on April 2010

Under-treatment of type 2 diabetes: Causes and outcomes of clinical inertia.

scientific article published on December 2016

Uric acid and the cardio-renal effects of SGLT2 inhibitors

scientific article published on 15 March 2019

Use of metformin in the setting of mild-to-moderate renal insufficiency

scientific article

Value of glycaemic control in diabetes

scientific article published on 01 January 2008

What are the practical implications for treating diabetes in light of recent evidence? Updated recommendations from the Global Partnership for Effective Diabetes Management

scientific article published in October 2009

Whence and whither the fixed-dose combination?

scientific article published on 01 May 2005

Why is Exubera being withdrawn?

scientific article published in December 2007

Paulina is supported by:

About Paulina

Help