List of works - Mercedes Fuertes

Broad MICA/B expression in the small bowel mucosa: a link between cellular stress and celiac disease

scientific article

Expansion of CD11b+Ly6G+Ly6Cint cells driven by medroxyprogesterone acetate in mice bearing breast tumors restrains NK cell effector functions

article

Histone deacetylase inhibitors impair NK cell viability and effector functions through inhibition of activation and receptor expression.

scientific article

Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8{alpha}+ dendritic cells

scientific article

Human M2 Macrophages Limit NK Cell Effector Functions through Secretion of TGF-β and Engagement of CD85j.

scientific article published on 27 December 2017

Human natural killer cell maturation defect supports in vivo CD56(bright) to CD56(dim) lineage development

scientific article

IL-27 stimulates human NK-cell effector functions and primes NK cells for IL-18 responsiveness

scientific article published on 02 December 2014

Innate immune sensing of cancer: clues from an identified role for type I IFNs

scientific article published on 22 June 2012

Interleukin (IL)-23 Stimulates IFN-γ Secretion by CD56bright Natural Killer Cells and Enhances IL-18-Driven Dendritic Cells Activation.

scientific article published in January 2017

Intracellular Expression of MICA in Activated CD4 T Lymphocytes and Protection from NK Cell-Mediated MICA-Dependent Cytotoxicity

scientific article published on 31 March 2006

Intracellular retention of the NKG2D ligand MHC class I chain-related gene A in human melanomas confers immune privilege and prevents NK cell-mediated cytotoxicity.

scientific article

Molecular profiling to identify relevant immune resistance mechanisms in the tumor microenvironment

scientific article published on 23 December 2010

NK Cells Restrain Spontaneous Antitumor CD8+ T Cell Priming through PD-1/PD-L1 Interactions with Dendritic Cells.

scientific article published on 24 June 2016

Nuclear factor (NF)-κB controls expression of the immunoregulatory glycan-binding protein galectin-1.

scientific article published in September 2011

Regulated expression of galectin-1 during T-cell activation involves Lck and Fyn kinases and signaling through MEK1/ERK, p38 MAP kinase and p70S6 kinase

scientific article published in December 2004

Regulatory Dendritic Cells Restrain NK Cell IFN-γ Production through Mechanisms Involving NKp46, IL-10, and MHC Class I–Specific Inhibitory Receptors

scientific article published on 31 July 2015

Regulatory functions of NK cells during infections and cancer

scientific article published on 23 October 2020

STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors.

scientific article

Therapeutic activity of high-dose intratumoral IFN-β requires direct effect on the tumor vasculature.

scientific article published on 12 September 2014

Tumour-experienced T cells promote NK cell activity through trogocytosis of NKG2D and NKp46 ligands

scientific article published on 05 June 2009

Type I interferon response and innate immune sensing of cancer

scientific article

Up-regulated expression of MICA on activated T lymphocytes involves Lck and Fyn kinases and signaling through MEK1/ERK, p38 MAP kinase, and calcineurin

scientific article published in June 2003

List of works by Mercedes Fuertes

Broad MICA/B expression in the small bowel mucosa: a link between cellular stress and celiac disease

Expansion of CD11b+Ly6G+Ly6Cint cells driven by medroxyprogesterone acetate in mice bearing breast tumors restrains NK cell effector functions

Histone deacetylase inhibitors impair NK cell viability and effector functions through inhibition of activation and receptor expression.

Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8{alpha}+ dendritic cells

Human M2 Macrophages Limit NK Cell Effector Functions through Secretion of TGF-β and Engagement of CD85j.

Human natural killer cell maturation defect supports in vivo CD56(bright) to CD56(dim) lineage development

IL-27 stimulates human NK-cell effector functions and primes NK cells for IL-18 responsiveness

Innate immune sensing of cancer: clues from an identified role for type I IFNs

Interleukin (IL)-23 Stimulates IFN-γ Secretion by CD56bright Natural Killer Cells and Enhances IL-18-Driven Dendritic Cells Activation.

Intracellular Expression of MICA in Activated CD4 T Lymphocytes and Protection from NK Cell-Mediated MICA-Dependent Cytotoxicity

Intracellular retention of the NKG2D ligand MHC class I chain-related gene A in human melanomas confers immune privilege and prevents NK cell-mediated cytotoxicity.

Molecular profiling to identify relevant immune resistance mechanisms in the tumor microenvironment

NK Cells Restrain Spontaneous Antitumor CD8+ T Cell Priming through PD-1/PD-L1 Interactions with Dendritic Cells.

Nuclear factor (NF)-κB controls expression of the immunoregulatory glycan-binding protein galectin-1.

Regulated expression of galectin-1 during T-cell activation involves Lck and Fyn kinases and signaling through MEK1/ERK, p38 MAP kinase and p70S6 kinase

Regulatory Dendritic Cells Restrain NK Cell IFN-γ Production through Mechanisms Involving NKp46, IL-10, and MHC Class I–Specific Inhibitory Receptors

Regulatory functions of NK cells during infections and cancer

STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors.

Therapeutic activity of high-dose intratumoral IFN-β requires direct effect on the tumor vasculature.

Tumour-experienced T cells promote NK cell activity through trogocytosis of NKG2D and NKp46 ligands

Type I interferon response and innate immune sensing of cancer

Up-regulated expression of MICA on activated T lymphocytes involves Lck and Fyn kinases and signaling through MEK1/ERK, p38 MAP kinase, and calcineurin