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List of works by Robert C. Bast

10th Biennial Helene Harris Memorial Trust Meeting

scientific article published on 01 March 2006

2000 update of recommendations for the use of tumor markers in breast and colorectal cancer: clinical practice guidelines of the American Society of Clinical Oncology

scientific article

395 POSTER CpG island methylator phenotype (CIMP): a novel biomaker to predict new therapy for breast cancer

4-HPR modulates gene expression in ovarian cells

scientific article published on September 2006

4-Hydroperoxycyclophosphamide purging of breast cancer from the mononuclear cell fraction of bone marrow in patients receiving high-dose chemotherapy and autologous marrow support: a phase I trial

scientific article published on 01 January 1991

6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase-2 Regulates TP53-Dependent Paclitaxel Sensitivity in Ovarian and Breast Cancers

scientific article published on 07 August 2019

801 ABSENCE OF COMMON ALL ANTIGEN ON NORMAL PLURIPOTENTIAL MYELOID, ERYTHROID AND GRANULOCYTE PROGENITORS

A 2-Stage Ovarian Cancer Screening Strategy Using the Risk of Ovarian Cancer Algorithm (ROCA) Identifies Early-Stage Incident Cancers and Demonstrates High Positive Predictive Value

A 2-stage ovarian cancer screening strategy using the Risk of Ovarian Cancer Algorithm (ROCA) identifies early-stage incident cancers and demonstrates high positive predictive value

scientific article published on 26 August 2013

A Bayesian approach to dose-response assessment and synergy and its application to in vitro dose-response studies

scientific article published on December 2010

A Comparison of Immunohistochemistry, Two-Color Immunofluorescence, and Flow Cytometry with Cell Sorting for the Detection of Micrometastatic Breast Cancer in the Bone Marrow

scientific article published on 01 February 1996

A Novel Compound ARN-3236 Inhibits Salt-Inducible Kinase 2 and Sensitizes Ovarian Cancer Cell Lines and Xenografts to Paclitaxel.

scientific article published on 27 September 2016

A Phase I Study of a Daily ×3 Schedule of Intravenous Vinorelbine for Refractory Epithelial Ovarian Cancer ⬇️

scientific article published on September 1, 1998

A Ras homologue member I directly inhibits signal transducers and activators of transcription 3 translocation and activity in human breast and ovarian cancer cells

scientific article published in August 2005

A framework for evaluating biomarkers for early detection: validation of biomarker panels for ovarian cancer

scientific article

A genetically defined model for human ovarian cancer

scientific article published on March 2004

A genistein derivative, ITB-301, induces microtubule depolymerization and mitotic arrest in multidrug-resistant ovarian cancer

scientific article

A multiplexable, microfluidic platform for the rapid quantitation of a biomarker panel for early ovarian cancer detection at the point-of-care

scientific article published on 11 November 2014

A novel hTERT promoter-driven E1A therapeutic for ovarian cancer.

scientific article published on 11 August 2009

A novel multiple marker bioassay utilizing HE4 and CA125 for the prediction of ovarian cancer in patients with a pelvic mass

scientific article published on 12 October 2008

A phase II study of imatinib mesylate and letrozole in patients with hormone receptor-positive metastatic breast cancer expressing c-kit or PDGFR-β

scientific article published on 11 October 2018

A phosphopeptide mimetic prodrug targeting the SH2 domain of Stat3 inhibits tumor growth and angiogenesis.

scientific article

A radioimmunoassay using a monoclonal antibody to monitor the course of epithelial ovarian cancer

scientific article

A study of the NB/70K and CA 125 monoclonal antibody radioimmunoassays for measuring serum antigen levels in ovarian cancer patients

article

ALTERED IMMUNOLOGIC RECONSTITUTION AFTER STANDARD-DOSE CHEMOTHERAPY OR HIGH-DOSE CHEMOTHERAPY WITH AUTOLOGOUS BONE MARROW SUPPORT

scientific article published on 01 July 1988

ARHI (DIRAS3) induces autophagy in ovarian cancer cells by downregulating the epidermal growth factor receptor, inhibiting PI3K and Ras/MAP signaling and activating the FOXo3a-mediated induction of Rab7

scientific article

ARHI (DIRAS3), an imprinted tumour suppressor gene, binds to importins and blocks nuclear import of cargo proteins

scientific article

ARHI (DIRAS3)-mediated autophagy-associated cell death enhances chemosensitivity to cisplatin in ovarian cancer cell lines and xenografts.

scientific article

ARHI is a Ras-related small G-protein with a novel N-terminal extension that inhibits growth of ovarian and breast cancers

scientific article

ARHI is the center of allelic deletion on chromosome 1p31 in ovarian and breast cancers

scientific article published on 01 June 2000

ASCO 2006 update of recommendations for the use of tumor markers in gastrointestinal cancer

scientific article

AUTOLOGOUS BONE-MARROW TRANSPLANTATION IN CALLA-POSITIVE ACUTE LYMPHOBLASTIC LEUKAEMIA AFTER IN-VITRO TREATMENT WITH J5 MONOCLONAL ANTIBODY AND COMPLEMENT

scientific article published in The Lancet

Aberrant methylation and silencing of ARHI, an imprinted tumor suppressor gene in which the function is lost in breast cancers.

scientific article

Absence of common ALL antigen on normal bipotent myeloid, erythroid, and granulocyte progenitors

scientific article published on 01 August 1981

Abstract 1151: IL-8, VEGF and IGF-1 play the important role in ARHI mediated-tumor dormancy in ovarian cancer

Abstract 2311: NDN, an imprinted tumor suppressor gene inhibits ovarian cancer cell growth and motility and is downregulated by genetic and epigenetic mechanisms

article

Abstract 2838: TP53 autoantibody can detect CA125 screen negative ovarian cancer cases and can be elevated prior to CA125 in preclinical ovarian cancer

Abstract 3032: A novel compound ARN-3236 inhibits SIK2 and sensitizes ovarian cancer to paclitaxel

Abstract 3456: MUC16/CA125, TNFα and IFNγ are co-expressed in malignant gynecologic neoplasms

Abstract 3473: Intra-person and inter-person biomarker variation for modeling longitudinal values of ovarian cancer early detection biomarkers

Abstract 3495: Multiplexed detection of early-stage ovarian cancer biomarkers using a microfluidic bead-based immunosensor

Abstract 3659: DIRAS1 and DIRAS2 are novel ovarian cancer tumor suppressors that regulate cell growth, motility and autophagy

Abstract 3762: Downregulation of TRPC3 enhances sensitivity to cisplatin and inhibits motility in epithelial ovarian cancer

Abstract 3827: Histone methytransferase SMYD3 promotes invasion in ovarian carcinoma spheroids

Abstract 4028: ARHI plays a critical role in ovarian cancer tumor dormancy by inhibition of angiogenesis switch

Abstract 438: Development of an autoantibody panel that reflects disease pathogenesis in ovarian cancer

article

Abstract 4670: Combinations of kinase siRNAs potentiates paclitaxel sensitivity in ovarian cancer

Abstract 4766: Follicle stimulating hormone (FSH) inhibits apoptosis in ovarian cancer cell through regulating OCT4 stem cell signal pathway

Abstract 4987: IL8, VEGF and IGF-1 rescue ovarian cancer cells undergoing ARHI-mediated- autophagic cell death

Abstract 5105: The imprinted tumor suppressor gene NDN inhibits cell motility in ovarian cancer by reactivating FAK and RhoA

article

Abstract 749: Highly potent and orally available SIK2 inhibitors block growth of human ovarian cancer cells in culture and xenografts

article

Abstract AS12: Integrating genomics, transcriptomics, and proteomics for the discovery of novel biomarkers to complement CA125 in ovarian cancer early detection

Abstract LB-119: Single-cell live imaging of paclitaxel-resistant cancer cell generation

article by Na Niu et al published 15 July 2016 in Cancer Research

Acquired cellular immunity: extracellular killing of Listeria monocytogenes by a product of immunologically activated macrophages

scientific article

Activated SRC protein tyrosine kinase is overexpressed in late-stage human ovarian cancers

scientific article

Activating and propagating polyclonal gamma delta T cells with broad specificity for malignancies

scientific article

Activation of the ras-mitogen-activated protein kinase pathway and phosphorylation of ets-2 at position threonine 72 in human ovarian cancer cell lines ⬇️

scientific article published on May 15, 1998

Additive and synergistic interactions of monoclonal antibodies and immunotoxins reactive with breast and ovarian cancer.

scientific article published on January 1994

Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2

article

Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2.

scientific article

American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer

scientific article

Amifostine (WR-2721) shortens the engraftment period of 4-hydroperoxycyclophosphamide-purged bone marrow in breast cancer patients receiving high-dose chemotherapy with autologous bone marrow support

scientific article published on 01 June 1994

Amino Acid Deprivation-Induced Autophagy Requires Upregulation of DIRAS3 through Reduction of E2F1 and E2F4 Transcriptional Repression.

scientific article published on 30 April 2019

An initial analysis of preoperative serum CA 125 levels in patients with early stage ovarian carcinoma

scientific article published in May 1988

Analysis of 96 patients with advanced ovarian carcinoma treated with high-dose chemotherapy and autologous stem cell transplantation

scientific article

Analysis of RAS protein interactions in living cells reveals a mechanism for pan-RAS depletion by membrane-targeted RAS binders

scientific article published on 18 May 2020

Anti-HER2 antibody and heregulin suppress growth of HER2-overexpressing human breast cancer cells through different mechanisms

scientific article published on 01 January 2000

Anti-HER2 antibody trastuzumab inhibits CDK2-mediated NPAT and histone H4 expression via the PI3K pathway.

scientific article

Antibody-induced growth inhibition is mediated through immunochemically and functionally distinct epitopes on the extracellular domain of the c-erbB-2 (HER-2/neu) gene product p185

scientific article published on 01 February 1993

Antigenic heterogeneity among Burkitt's lymphoma cells surviving treatment with monoclonal antibody and complement.

scientific article published in January 1986

Antigenic heterogeneity in human ovarian cancer

scientific article

Antigenic heterogeneity in human ovarian cancer

Antitumor activity of bacterial infection. I. Effect of Listeria monocytogenes on growth of a murine fibrosarcoma

scientific article published on March 1, 1975

Antitumor activity of bacterial infection. II. effect of Listeria monocytogenes on growth of a guinea pig hepatoma

scientific article published on March 1, 1975

Application of Monoclonal Antibodies to Autologous Bone Marrow Transplantation

article

Aryl hydrocarbon (benzo(a)pyrene) hydroxylase in human peripheral blood monocytes

scientific article

Aryl hydrocarbon (benzo(alpha)pyrene) hydroxylase in guinea pig peritoneal macrophages: benz(alpha)anthracene-induced increase of enzyme activity in vivo and in cell culture

scientific article published on August 1, 1973

Aryl hydrocarbon (benzo[a]pyrene) hydroxylase in guinea pig lymphoid tissue.

scientific article

Aurora kinase inhibitor VE 465 synergistically enhances cytotoxicity of carboplatin in ovarian cancer cells through induction of apoptosis and downregulation of histone 3

scientific article

BCG and cancer

scientific article published on June 1974

BCG and cancer (first of two parts).

scientific article

Biochemistry and Biology of ARHI (DIRAS3), an Imprinted Tumor Suppressor Gene Whose Expression Is Lost in Ovarian and Breast Cancers

article

Biology and therapy with biologic agents in gynecologic cancer.

scientific article published on October 1992

Biomarkers and Strategies for Early Detection of Ovarian Cancer

scientific article published on 13 October 2020

Biomarkers for ovarian cancer: New technologies and targets to address persistently unmet needs

scientific article published on November 3, 2011

Biomarkers, surrogate end points, and the acceleration of drug development for cancer prevention and treatment: an update prologue

scientific article published on June 2004

Breast cancer cells are effectively purged from peripheral blood progenitor cells with an immunomagnetic technique

scientific article published on 01 January 1996

Bystander suppression of tumor growth: evidence that specific targets and bystanders are damaged by injury to a common microvasculature ⬇️

scientific article published on August 1, 1982

CA 125 Serum Levels Correlated With Second-Look Operations Among Ovarian Cancer Patients

article

CA 125 assay used in conjunction with CA 15-3 and TAG-72 assays for discrimination between malignant and non-malignant diseases of the ovary

scientific article published on January 1989

CA 125 for the monitoring of ovarian carcinoma during primary therapy

scientific article published on 01 February 1987

CA 125 in ovarian cancer: advances and controversy ⬇️

scientific article published on July 1, 1998

CA 125 in peritoneal fluid and serum from patients with benign gynecologic conditions and ovarian cancer

scientific article published in February 1990

CA 125 levels in patients with ovarian carcinoma undergoing autologous bone marrow transplantation

scientific article published on 01 February 1989

CA 125 serum levels correlate with second-look operations among ovarian cancer patients: A prospective multi-institutional study

CA 125: the past and the future

scientific article

CA-125 level as a prognostic indicator in type I and type II epithelial ovarian cancer.

scientific article published on June 2013

CA125 antigen levels in obstetric and gynecologic patients

scientific article published on 01 November 1984

CA125/MUC16 is dispensable for mouse development and reproduction

scientific article

CDK5 Regulates Paclitaxel Sensitivity in Ovarian Cancer Cells by Modulating AKT Activation, p21Cip1- and p27Kip1-Mediated G1 Cell Cycle Arrest and Apoptosis

scientific article published on 6 July 2015

Carcinoma of the Pancreas

article

Caspase-3 Substrates for Noninvasive Pharmacodynamic Imaging of Apoptosis by PET/CT

scientific article published on 31 August 2018

Cell Origins of High-Grade Serous Ovarian Cancer

Cell growth regulation in epithelial ovarian cancer.

scientific article

Cell surface density of p185(c-erbB-2) determines susceptibility to anti-p185(c-erbB-2)-ricin A chain (RTA) immunotoxin therapy alone and in combination with anti-p170(EGFR)-RTA in ovarian cancer cells ⬇️

scientific article published on 01 October 1998

Characterization of gelatinases linked to extracellular matrix invasion in ovarian adenocarcinoma: purification of matrix metalloproteinase 2.

scientific article published on July 1996

Characterization of the ARHI Tumor-Suppressor as a Target for Gene Therapy in Ovarian Cancer*

article

Characterization of the CA 125 antigen associated with human epithelial ovarian carcinomas.

scientific article

Chemotherapy: A new standard combination for recurrent ovarian cancer?

scientific article

Circulating DF3 and CA125 antigen levels in serum from patients with epithelial ovarian carcinoma

scientific article published in October 1985

Clinical Applications of Monoclonal Antibodies in Acute Leukemia

article

Clinical Use of Cancer Biomarkers in Epithelial Ovarian Cancer: Updated Guidelines From the European Group on Tumor Markers

scientific article

Clinical and laboratory directions for ovarian cancer research

scientific article published on December 1994

Clinical and pharmacologic effects of high dose single agent busulfan with autologous bone marrow support in the treatment of solid tumors

scientific article published in December 1987

Clinical application of oxaliplatin in epithelial ovarian cancer.

scientific article published on September 2006

Clinical trial endpoints in ovarian cancer: report of an FDA/ASCO/AACR Public Workshop.

scientific article published in November 2007

Clinically relevant microRNAs in ovarian cancer

scientific article

Clonal origin of epithelial ovarian carcinoma: analysis by loss of heterozygosity, p53 mutation, and X-chromosome inactivation

scientific article published on December 1992

Co-expression of human cancer-associated epitopes on mucin molecules

scientific article published on 01 January 1987

Coevolution of neoplastic epithelial cells and multilineage stroma via polyploid giant cells during immortalization and transformation of mullerian epithelial cells

scientific article published on March 2016

Coexpression of different antigenic markers on moieties that bear CA 125 determinants

scientific article published on January 1991

Coexpression of the HER-2 Gene Product, pl85HER-2, and Epidermal Growth Factor Receptor, pl70EGF-R, on Epithelial Ovarian Cancers and Normal Tissues

article

Combination of 4-HPR and oral contraceptive in monkey model of chemoprevention of ovarian cancer

scientific article published on January 2007

Combination of multiple serum markers using an artificial neural network to improve specificity in discriminating malignant from benign pelvic masses

scientific article published in April 1999

Combined chemoseparation and immunoseparation of clonogenic T lymphoma cells from human bone marrow using 2'-deoxycoformycin, deoxyadenosine, 3A1 monoclonal antibody, and complement

scientific article published on 01 September 1987

Combined use of biomarkers for detection of ovarian cancer in high-risk women

scientific article published on 01 June 2010

Combining multiple serum tumor markers improves detection of stage I epithelial ovarian cancer

scientific article

Comparison of a novel assay for breast cancer mucin to CA15-3 and carcinoembryonic antigen

scientific article published in July 1992

Comparison of a novel multiple marker assay vs the Risk of Malignancy Index for the prediction of epithelial ovarian cancer in patients with a pelvic mass

scientific article

Comparison of a rabbit heteroantiserum and a murine monoclonal antibody raised against a human epithelial ovarian carcinoma cell line ⬇️

scientific article published on July 15, 1983

Complementary Longitudinal Serum Biomarkers to CA125 for Early Detection of Ovarian Cancer

scientific article published on 09 April 2019

Conquering Cancer in Our Lifetime: New Diagnostic and Therapeutic Trends ⬇️

scientific article published on November 30, 2012

Constitutive Production of Macrophage Colony-Stimulating Factor and Interleukin-6 by Human Ovarian Surface Epithelial Cells

scientific article published on 01 August 1993

Constitutive production of macrophage colony-stimulating factor by human ovarian and breast cancer cell lines

scientific article

Contrasting effects of cyclophosphamide and prednisolone on the phenotype of human peripheral blood leukocytes

scientific article published on 01 July 1983

Coordinate elevation of serum markers in ovarian cancer but not in benign disease

scientific article published on 01 October 1991

Coordinate expression of urinary-type plasminogen activator and its receptor accompanies malignant transformation of the ovarian surface epithelium

scientific article

Correction: Paclitaxel Sensitivity of Ovarian Cancer Can be Enhanced by Knocking Down Pairs of Kinases that Regulate MAP4 Phosphorylation and Microtubule Stability

scientific article published on 01 September 2020

Correlation between CpG methylation profiles and hormone receptor status in breast cancers

scientific article

Corrigendum: Enhanced Cytotoxic Effects of Combined Valproic Acid and the Aurora Kinase Inhibitor VE465 on Gynecologic Cancer Cells

scientific article published on 9 February 2018

Critical questions in ovarian cancer research and treatment: Report of an American Association for Cancer Research Special Conference

article

Current state of biomarker development for clinical application in epithelial ovarian cancer

scientific article

Cutaneous basophil hypersensitivity. 3. Participation of the basophil in hypersensitivity to antigen-antibody complexes, delayed hypersensitivity and contact allergy. Passive transfer

scientific article published on July 1, 1971

Cyclin G1 regulates the outcome of taxane-induced mitotic checkpoint arrest

scientific article

Cytotoxic T-lymphocytes derived from patients with breast adenocarcinoma recognize an epitope present on the protein core of a mucin molecule preferentially expressed by malignant cells ⬇️

scientific article published on 01 June 1991

DIRAS3 (ARHI) Blocks RAS/MAPK Signaling by Binding Directly to RAS and Disrupting RAS Clusters

scientific article published on 01 December 2019

DIRAS3 regulates the autophagosome initiation complex in dormant ovarian cancer cells

scientific article

DIRAS3-Derived Peptide Inhibits Autophagy in Ovarian Cancer Cells by Binding to Beclin1.

scientific article

DIRAS3: An Imprinted Tumor Suppressor Gene that Regulates RAS and PI3K-driven Cancer Growth, Motility, Autophagy, and Tumor Dormancy

scientific article published in January 2022

Dasatinib induces autophagic cell death in human ovarian cancer

scientific article

Decitabine and suberoylanilide hydroxamic acid (SAHA) inhibit growth of ovarian cancer cell lines and xenografts while inducing expression of imprinted tumor suppressor genes, apoptosis, G2/M arrest, and autophagy

scientific article

Decreased Src tyrosine kinase activity inhibits malignant human ovarian cancer tumor growth in a nude mouse model.

scientific article published on August 1999

Detection of a novel marker in the bronchial secretions of patients with non-small cell lung cancer using the 4B5 monoclonal antibody

scientific article published on June 15, 1992

Detection of breast carcinoma cells in human bone marrow using fluorescence-activated cell sorting and conventional cytology

scientific article published on 01 July 1990

Detection of tumor cells in the bone marrow of stage IV breast cancer patients receiving high-dose chemotherapy: the role of induction chemotherapy

scientific article published on 01 December 1995

Determination of proliferation index in advanced ovarian cancer using quantitative image analysis

scientific article published on 01 June 1993

Determination of proliferation index with MIB-1 in advanced ovarian cancer using quantitative image analysis

scientific article published on 01 February 1994

Development of a multimarker assay for early detection of ovarian cancer

scientific article published on 5 April 2010

Development of an assay for aryl hydrocarbon (benzo(a)pyrene) hydroxylase in human peripheral blood monocytes ⬇️

scientific article published on June 1, 1976

Differential diagnosis of a pelvic mass: improved algorithms and novel biomarkers

scientific article

Differential diagnosis of ovarian cancer with tumour markers CA 125, CA 15-3 and TAG 72.3

scientific article published on 01 December 1993

Differential expression of the 67-kD laminin receptor and 31-kD human laminin-binding protein in human ovarian carcinomas

scientific article published on 01 January 1994

Differential induction by interferons of major histocompatibility complex-encoded and non-major histocompatibility complex-encoded antigens in human breast and ovarian carcinoma cell lines

scientific article published on 01 June 1989

Dissecting "PI3Kness": the complexity of personalized therapy for ovarian cancer

scientific article

Downregulation of TRIM27 expression inhibits the proliferation of ovarian cancer cells in vitro and in vivo

scientific article published on 16 November 2015

Early Detection of Ovarian Cancer

article

Early Detection of Ovarian Cancer: Promise and Reality ⬇️

scientific article published on January 1, 2002

Early detection of ovarian cancer

scientific article

Early detection of ovarian cancer.

scientific article

Effect of Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor on Hematopoietic Reconstitution after High-Dose Chemotherapy and Autologous Bone Marrow Transplantation

scientific article published on 01 April 1988

Elevated serum concentrations of CA-125 in patients with advanced endometriosis

scientific article published on 01 May 1986

Elevation of CA-125 prior to recurrence of ovarian cancer

Elevation of TP53 Autoantibody Before CA125 in Preclinical Invasive Epithelial Ovarian Cancer

scientific article published on 21 June 2017

Elevation of multiple serum markers in patients with stage I ovarian cancer

scientific article

Elevation of serum CA 125 prior to diagnosis of an epithelial ovarian carcinoma

scientific article published on 01 September 1985

Elevation of serum CA125 in carcinomas of the fallopian tube, endometrium, and endocervix

article

Elimination of clonogenic Burkitt's lymphoma cells from human bone marrow using 4-hydroperoxycyclophosphamide in combination with monoclonal antibodies and complement

scientific article published on 01 May 1985

Elimination of clonogenic breast cancer cells from human bone marrow. A comparison of immunotoxin treatment with chemoimmunoseparation using 4-hydroperoxycyclophosphamide, monoclonal antibodies, and magnetic microspheres

scientific article published on September 1991

Elimination of clonogenic tumor cells from human bone marrow using a combination of monoclonal antibody:ricin A chain conjugates

scientific article published on 01 March 1986

Elimination of dormant, autophagic ovarian cancer cells and xenografts through enhanced sensitivity to anaplastic lymphoma kinase inhibition

scientific article published on 02 June 2020

Elimination of leukemic cells from human bone marrow using monoclonal antibody and complement ⬇️

scientific article published on 01 March 1983

Elimination of leukemic cells from rat bone marrow using antibody and complement

scientific article published on 01 September 1981

Elimination of malignant clonogenic breast cancer cells from human bone marrow

scientific article published on 01 August 1989

Elimination of malignant clonogenic cells from human bone marrow using multiple monoclonal antibodies and complement

scientific article published in February 1985

Enhanced Cytotoxic Effects of Combined Valproic Acid and the Aurora Kinase Inhibitor VE465 on Gynecologic Cancer Cells

scientific article published on 20 March 2013

Enhanced arachidonic acid lipoxygenation by K562 cells stimulated with 12-O-tetradecanoylphorbol-13-acetate

scientific article published on 01 January 1983

Epac1 knockdown inhibits the proliferation of ovarian cancer cells by inactivating AKT/Cyclin D1/CDK4 pathway in vitro and in vivo

scientific article published on 8 June 2016

Epidermal growth factor receptor expression in normal and malignant endometrium

scientific article published in November 1989

Epidermal growth factor receptor expression in normal ovarian epithelium and ovarian cancer

scientific article published on 01 March 1991

Epidermal growth factor receptor expression in normal ovarian epithelium and ovarian cancer. I. Correlation of receptor expression with prognostic factors in patients with ovarian cancer.

scientific article published in February 1991

Epigenetic regulation of ARHI in breast and ovarian cancer cells

scientific article

Establishment and characterization of cancer cell cultures and xenografts derived from primary or metastatic Mullerian cancers.

scientific article

Expression and amplification of the HER-2/ neu (c-erbB-2) protooncogene in epithelial ovarian tumors and cell lines

scientific article published on 01 September 1991

Expression and epigenetic regulation of angiogenesis-related factors during dormancy and recurrent growth of ovarian carcinoma

scientific article published on 17 October 2013

Expression of BAG-1 and BcL-2 proteins before and after neoadjuvant chemotherapy of locally advanced breast cancer

scientific article published in January 2004

Expression of cell regulatory proteins in ovarian borderline tumors

scientific article published on 01 May 1996

Expression of epidermal growth factor receptor and HER-2/neu in normal and neoplastic cervix, vulva, and vagina

scientific article published on September 1990

Expression of major histocompatibility antigens and nature of inflammatory cellular infiltrate in ovarian neoplasms ⬇️

scientific article published on November 15, 1983

Expression of p16 induces transcriptional downregulation of the RB gene

scientific article

Expression of p53 in cisplatin-resistant ovarian cancer cell lines: modulation with the novel platinum analogue (1R, 2R-diaminocyclohexane)(trans-diacetato)(dichloro)-platinum(IV)

scientific article published on 01 March 1999

Expression of the 67-kD laminin receptor, galectin-1, and galectin-3 in advanced human uterine adenocarcinoma

scientific article published on 01 November 1996

Expression of the tumor suppressor gene ARHI in epithelial ovarian cancer is associated with increased expression of p21WAF1/CIP1 and prolonged progression-free survival

scientific article published on 01 October 2004

FOXO3a-Dependent Mechanism of E1A-Induced Chemosensitization

scientific article published on 12 September 2011

FSH enhances the proliferation of ovarian cancer cells by activating transient receptor potential channel C3.

scientific article published on 30 May 2013

Fibronectin is an immunosuppressive substance associated with epithelial ovarian cancer

scientific article published in October 1992

Fluorescence spectroscopy as a biomarker in a cell culture and in a nonhuman primate model for ovarian cancer chemopreventive agents

scientific article published in January 2002

Follicle-stimulating hormone inhibits apoptosis in ovarian cancer cells by regulating the OCT4 stem cell signaling pathway

scientific article published on 06 August 2013

Functional evidence for an ovarian cancer tumor suppressor gene on chromosome 22 by microcell-mediated chromosome transfer

scientific article

Future for ovarian cancer screening: novel markers from emerging technologies of transcriptional profiling and proteomics

scientific article

Gankyrin facilitates follicle-stimulating hormone-driven ovarian cancer cell proliferation through the PI3K/AKT/HIF-1α/cyclin D1 pathway

scientific article published on 14 September 2015

Gene expression profiles predict early relapse in ovarian cancer after platinum-paclitaxel chemotherapy

article

General keynote: molecular therapeutics and pharmocogenomics

scientific article

Genes affecting the cell cycle, growth, maintenance, and drug sensitivity are preferentially regulated by anti-HER2 antibody through phosphatidylinositol 3-kinase-AKT signaling

scientific article

Genetic analysis of early- versus late-stage ovarian tumors.

scientific article published in August 2001

Genomic structure and promoter characterization of an imprinted tumor suppressor gene ARHI.

scientific article

Growth regulation and transformation of ovarian epithelium

scientific article published on January 1993

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

article by Daniel J Klionsky et al published January 2021 in Autophagy

Gynecologic tumor markers

scientific article published on January 1990

HER2 signaling modulates the equilibrium between pro- and antiangiogenic factors via distinct pathways: implications for HER2-targeted antibody therapy.

scientific article

HER2-targeting antibodies modulate the cyclin-dependent kinase inhibitor p27Kip1 via multiple signaling pathways

scientific article

Ha-ras polymorphisms in epithelial ovarian cancer

scientific article published in June 1992

Heregulin and agonistic anti-p185(c-erbB2) antibodies inhibit proliferation but increase invasiveness of breast cancer cells that overexpress p185(c-erbB2): increased invasiveness may contribute to poor prognosis

scientific article published on September 1997

Heregulin-induced apoptosis is mediated by down-regulation of Bcl-2 and activation of caspase-7 and is potentiated by impairment of protein kinase C alpha activity

scientific article published on December 2001

Heterogeneity of antigen expression in advanced epithelial ovarian cancer

scientific article published on April 1990

Heterogeneity of antigen expression in benign and malignant breast and ovarian epithelial cells

scientific article published on 01 January 1989

Heterogeneity of the cellular immune response. I. Kinetics of lymphocyte stimulation during sensitization and recovery from tolerance

scientific article published on February 1971

Heterogeneity of the cellular immune response. II. The role of adjuvant, lymphocyte stimulation in cutaneous basophil hypersensitivity

scientific article published on February 1971

High dose methotrexate with leucovorin rescue. Rationale and spectrum of antitumor activity

scientific article published on March 1980

High-dose alkylating agent chemotherapy with autologous bone marrow support in patients with stage III/IV epithelial ovarian cancer

scientific article published on 01 September 1990

High-dose chemotherapy and autologous bone marrow support as consolidation after standard-dose adjuvant therapy for high-risk primary breast cancer

scientific article published on 01 June 1993

High-dose combination alkylating agents with autologous bone marrow support: a Phase 1 trial.

scientific article

High-dose combination alkylating agents with bone marrow support as initial treatment for metastatic breast cancer

scientific article published on 01 September 1988

High-dose combination cyclophosphamide, cisplatin, and melphalan with autologous bone marrow support

scientific article published on 01 January 1989

High-dose topotecan, melphalan, and cyclophosphamide (TMC) with stem cell support: a new regimen for the treatment of advanced ovarian cancer

scientific article published on September 2001

Homologous and heterologous desensitization of proto-oncogene cfos expression in murine peritoneal macrophages

article

How do you distinguish a malignant pelvic mass from a benign pelvic mass? Imaging, biomarkers, or none of the above

scientific article published on 13 August 2007

How will we recruit, train, and retain physicians and scientists to conduct translational cancer research?

scientific article

Human epididymis protein 4 antigen-autoantibody complexes complement cancer antigen 125 for detecting early-stage ovarian cancer

scientific article published on 12 November 2019

IL-6 promotes drug resistance through formation of polyploid giant cancer cells and stromal fibroblast reprogramming

scientific article published on 29 September 2021

Immunochemical characterization and radioimmunometric detection of molecules shed by human ovarian cancer

scientific article published on 01 November 1987

Immunohistochemical characterization of 22 monoclonal antibodies against the CA125 antigen: 2nd report from the ISOBM TD-1 Workshop

scientific article

Immunohistochemical expression of CA 125 in endometrial adenocarcinoma: correlation of antigen expression with metastatic potential

scientific article published on 01 April 1989

Immunohistochemical expression of TAG-72 in normal and malignant endometrium: correlation of antigen expression with estrogen receptor and progesterone receptor levels

scientific article published in November 1989

Immunologic unresponsiveness in the adult guinea pig. IV. Induction of unresponsiveness with aggregated serum proteins.

scientific article

Immunomagnetic purging of breast cancer from bone marrow for autologous transplantation

scientific article published on 01 February 1991

Immunopathologic characterization of a monoclonal antibody that recognizes common surface antigens of human ovarian tumors of serous, endometrioid, and clear cell types

scientific article published on 01 January 1983

Immunopharmacologic purging of breast cancer from bone marrow for autologous bone marrow transplantation

scientific article published on 01 January 1990

Immunoprophylaxis of syngeneic methycholanthrene-induced murine sarcomas with Bacillus Calmette-Guérin and tumor cells

scientific article published on 01 April 1980

Immunotherapy of a murine ovarian carcinoma with Corynebacterium parvum and specific heteroantiserum. I. Activation of peritoneal cells to mediate antibody-dependent cytotoxicity ⬇️

scientific article published on 01 November 1979

Imprinted tumor suppressor gene ARHI induces apoptosis correlated with changes in DNA methylation in pancreatic cancer cells

scientific article

Imprinted tumor suppressor genes ARHI and PEG3 are the most frequently down-regulated in human ovarian cancers by loss of heterozygosity and promoter methylation

scientific article

In Support of a Patient-Driven Initiative and Petition to Lower the High Price of Cancer Drugs

scientific article published on 23 July 2015

In Vivo Optical Detection and Spectral Triangulation of Carbon Nanotubes

scientific article

In vitro model of normal, immortalized ovarian surface epithelial and ovarian cancer cells for chemoprevention of ovarian cancer

scientific article

In vitro treatment with monoclonal antibody prior to autologous bone marrow transplantation in acute lymphoblastic leukemia

scientific article published on 01 January 1983

In vivo modeling of metastatic human high-grade serous ovarian cancer in mice

scientific article published on 04 June 2020

Increased serum levels of macrophage colony-stimulating factor in ovarian cancer

scientific article published in November 1991

Individualized care for patients with cancer - a work in progress

scientific article published on 10 December 2004

Induction of autophagy by ARHI (DIRAS3) alters fundamental metabolic pathways in ovarian cancer models

scientific article

Induction of papillary carcinoma in human ovarian surface epithelial cells using combined genetic elements and peritoneal microenvironment

scientific article

Induction of tumor immunity by intratumoral chemotherapy

scientific article

Influence of circulating antigen on blood pool activity of a radioiodinated monoclonal antibody

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Preoperative sensitivity and specificity for early-stage ovarian cancer when combining cancer antigen CA-125II, CA 15-3, CA 72-4, and macrophage colony-stimulating factor using mixtures of multivariate normal distributions.

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Prognostic significance of p53 expression in advanced-stage ovarian serous borderline tumors.

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Pros and cons of gynecologic tumor markers

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Proteome Profiling Uncovers an Autoimmune Response Signature That Reflects Ovarian Cancer Pathogenesis

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Proteomic biomarkers apolipoprotein A1, truncated transthyretin and connective tissue activating protein III enhance the sensitivity of CA125 for detecting early stage epithelial ovarian cancer

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Proteomic biomarkers in combination with CA 125 for detection of epithelial ovarian cancer using prediagnostic serum samples from the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial

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Proteomics analysis of H-RAS-mediated oncogenic transformation in a genetically defined human ovarian cancer model

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RAS-related GTPases DIRAS1 and DIRAS2 induce autophagic cancer cell death and are required for autophagy in murine ovarian cancer cells.

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Radioiodinated antibody targeting of the HER-2/neu oncoprotein

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Radioiodinated antibody targeting of the HER-2/neu oncoprotein: effects of labeling method on cellular processing and tissue distribution

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Reactivation of the silenced and imprinted alleles of ARHI is associated with increased histone H3 acetylation and decreased histone H3 lysine 9 methylation

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Reactivity of a monoclonal antibody with human ovarian carcinoma

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Reactivity of epidermal growth factor receptor monoclonal antibodies with human uterine tissues

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Recombinant leukocyte alpha interferon in advanced ovarian carcinoma

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Reexpression of the retinoblastoma protein in tumor cells induces senescence and telomerase inhibition

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Reexpression of the tumor suppressor gene ARHI induces apoptosis in ovarian and breast cancer cells through a caspase-independent calpain-dependent pathway

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Regression of Established Tumors and Induction of Tumor Immunity by Intratumor Chemotherapy ⬇️

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Regulation of BAD phosphorylation at serine 112 by the Ras-mitogen-activated protein kinase pathway

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Regulation of invasion of epithelial ovarian cancer by transforming growth factor-beta

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Regulation of tumour necrosis factor-alpha processing by a metalloproteinase inhibitor

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Relative cytotoxic activity of immunotoxins reactive with different epitopes on the extracellular domain of the c-erbB-2 (HER-2/neu) gene product p185.

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Reply to Comment on "Osteopontin, Macrophage Migration Inhibitory Factor and Anti-Interleukin-8 Autoantibodies Complement CA125 for Detection of Early Stage Ovarian Cancer" Cancers 2019, 11, 596: Markers for Early Detection of Ovarian Cancer

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Reproducibility of SELDI Spectra Across Time and Laboratories

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Requirements for the internalization of a murine monoclonal antibody directed against the HER-2/neu gene product c-erbB-2 ⬇️

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Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer

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Rethinking ovarian cancer: recommendations for improving outcomes

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Risk perception, worry, and test acceptance in average-risk women who undergo ovarian cancer screening

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Roles of human epidermal growth factor receptor 2, c-jun NH2-terminal kinase, phosphoinositide 3-kinase, and p70 S6 kinase pathways in regulation of cyclin G2 expression in human breast cancer cells

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SCC antigen. Summary remarks

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SIK2 is a centrosome kinase required for bipolar mitotic spindle formation that provides a potential target for therapy in ovarian cancer

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SMYD3 promotes implant metastasis of ovarian cancer via H3K4 trimethylation of integrin promoters

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Salt-Inducible Kinase 2 Couples Ovarian Cancer Cell Metabolism with Survival at the Adipocyte-Rich Metastatic Niche

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Screening for ovarian cancer. Multiple markers may outperform CA 125 alone.

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Screening for ovarian cancer: imaging challenges and opportunities for improvement.

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Selection of potential markers for epithelial ovarian cancer with gene expression arrays and recursive descent partition analysis

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Serotherapy and Bone Marrow Transplantation

Serotherapy of ovarian cancer

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Serum CA 125 levels in a group of nonhospitalized women: relevance for the early detection of ovarian cancer

Serum HE4 levels are less frequently elevated than CA125 in women with benign gynecologic disorders ⬇️

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Serum biomarker panels for the discrimination of benign from malignant cases in patients with an adnexal mass

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Serum levels of HER-2 neu (C-erbB-2) correlate with overexpression of p185neu in human ovarian cancer

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Serum levels of the ovarian cancer biomarker HE4 are decreased in pregnancy and increase with age.

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Simultaneous Measurement of 92 Serum Protein Biomarkers for the Development of a Multiprotein Classifier for Ovarian Cancer Detection

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Somatic activation of rasK gene in a human ovarian carcinoma

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Specific keynote: molecular therapeutics in ovarian cancer

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Specificity and Affinity of 26 Monoclonal Antibodies against the CA 125 Antigen: First Report from the ISOBM TD-1 Workshop

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Specificity of heteroantisera developed against purified populations of intact murine ovarian carcinoma cells

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Spectral differences between epitopes in the cronomes of salivary CA130 and CA125

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Spectrum of mutation and frequency of allelic deletion of the p53 gene in ovarian cancer

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Src family kinases and paclitaxel sensitivity

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Stanniocalcin 1 and ovarian tumorigenesis

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Status of Tumor Markers in Ovarian Cancer Screening ⬇️

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Stimulation of ovarian tumor cell proliferation with monocyte products including interleukin-1, interleukin-6, and tumor necrosis factor-α

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Strategies for improving the specificity of screening for ovarian cancer with tumor-associated antigens CA 125, CA 15-3, and TAG 72.3 ⬇️

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Subcellular localization of p27kip1 expression predicts poor prognosis in human ovarian cancer.

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Suppression of diacylglycerol levels by antibodies reactive with the c-erbB-2 (HER-2/neu) gene product p185c-erbB-2 in breast and ovarian cancer cell lines

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Synergistic cytotoxicity of different alkylating agents for epithelial ovarian cancer

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Synergistic interaction between anti-p185HER-2 ricin A chain immunotoxins and radionuclide conjugates for inhibiting growth of ovarian and breast cancer cells that overexpress HER-2

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Targeting Aurora kinases in ovarian cancer

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Targeting aldehyde dehydrogenase cancer stem cells in ovarian cancer

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The CA 125 assay as a predictor of clinical recurrence in epithelial ovarian cancer

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The National Cancer Institute Early Detection Research Network: Two Decades of Progress

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The Roles of MicroRNAs in the Cancer Invasion-Metastasis Cascade

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The biology of ovarian cancer

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The biology of ovarian cancer: new opportunities for translation

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The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis

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The early competence genes JE and KC are differentially regulated in murine peritoneal macrophages in response to lipopolysaccharide

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The effect of LPS on expression of the early "competence" genes JE and KC in murine peritoneal macrophages.

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The effect of antibodies and immunotoxins reactive with HER-2/neu on growth of ovarian and breast cancer cell lines

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The effect of interferon gamma on epidermal growth factor receptor expression in normal and malignant ovarian epithelial cells

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The half-life of aryl hydrocarbon (benzo(a)pyrene) hydroxylase in human blood monocytes

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The human ARHI tumor suppressor gene inhibits lactation and growth in transgenic mice

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The origin of ovarian cancer

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The outcome of heregulin-induced activation of ovarian cancer cells depends on the relative levels of HER-2 and HER-3 expression

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The p53 tumor suppressor gene frequently is altered in gynecologic cancers

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The prognostic significance of CA 125 half-life in patients with ovarian cancer who have received primary chemotherapy after surgical cytoreduction

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The role of biomarkers in the management of epithelial ovarian cancer

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The role of constitutively active signal transducer and activator of transcription 3 in ovarian tumorigenesis and prognosis

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The role of cyclin-dependent kinase inhibitor p27Kip1 in anti-HER2 antibody-induced G1 cell cycle arrest and tumor growth inhibition

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The role of p27(Kip1) in dasatinib-enhanced paclitaxel cytotoxicity in human ovarian cancer cells

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The role of peptide growth factors in epithelial ovarian cancer.

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The role of tumor markers in gynecologic oncology.

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The role of vascular endothelial growth factor, interleukin 8, and insulinlike growth factor in sustaining autophagic DIRAS3‐induced dormant ovarian cancer xenografts

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The significance of tumor contamination in the bone marrow from high-risk primary breast cancer patients treated with high-dose chemotherapy and hematopoietic support

scientific article published on 01 June 1997

The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells

scientific article published on 20 November 2008

The tumor suppressor geneARHI(DIRAS3)inhibits ovarian cancer cell migration through multiple mechanisms ⬇️

scientific article published on January 28, 2013

The tumor-suppressor gene ARHI (DIRAS3) suppresses ovarian cancer cell migration through inhibition of the Stat3 and FAK/Rho signaling pathways

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The tyrosine kinase activity of the C-erbB-2 gene product (p185) is required for growth inhibition by anti-p185 antibodies but not for the cytotoxicity of an anti-p185-ricin-A chain immunotoxin

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The use of multiple novel tumor biomarkers for the detection of ovarian carcinoma in patients with a pelvic mass.

scientific article published on 3 December 2007

The use of tumor markers in the management of patients with gynecologic carcinomas

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Three Biomarkers Identified from Serum Proteomic Analysis for the Detection of Early Stage Ovarian Cancer

scientific article published on 01 August 2004

Tissue Distribution of a Coelomic- Epithelium-Related Antigen Recognized by the Monoclonal Antibody OC125

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Toward an optimal algorithm for ovarian cancer screening with longitudinal tumor markers

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Toward salivary-urinary chronosensitivity testing: chronomes of OVX1, M-CSF and CA130

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Transcriptional and posttranscriptional down-regulation of the imprinted tumor suppressor gene ARHI (DRAS3) in ovarian cancer

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Transcriptional regulation of core autophagy and lysosomal genes by the androgen receptor promotes prostate cancer progression.

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Transfection of human ovarian cancer cells with the HER-2/neu receptor tyrosine kinase induces a selective increase in PTP-H1, PTP-1B, PTP-alpha expression

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Transfection of ovarian cancer cells with tumor necrosis factor-alpha (TNF-alpha) antisense mRNA abolishes the proliferative response to interleukin-1 (IL-1) but not TNF-alpha

scientific article published on April 1994

Transforming growth factor beta 1 can induce CIP1/WAF1 expression independent of the p53 pathway in ovarian cancer cells ⬇️

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Transforming growth factor-beta inhibits proliferation of human ovarian cancer cells obtained from ascites

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Translational crossroads for biomarkers

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Translational research--traffic on the bridge.

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Treatment of murine peritoneal macrophages with bacterial lipopolysaccharide alters expression of c-fos and c-myc oncogenes

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Tumor Suppressor Genes

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Tumor antigen NB/70K and CA 125 levels in the blood of preoperative ovarian cancer patients and controls: a preliminary report of the use of the NB12123 and CA 125 radioimmunoassays alone and in combination

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Tumor marker utility grading system: a framework to evaluate clinical utility of tumor markers

scientific article published on October 1996

Tumor necrosis factor alpha as an autocrine and paracrine growth factor for ovarian cancer: monokine induction of tumor cell proliferation and tumor necrosis factor alpha expression

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Tumor necrosis factor-α and interferon-γ stimulate MUC16 (CA125) expression in breast, endometrial and ovarian cancers through NFκB.

scientific article published on 24 February 2016

Tumor suppressor genes are frequently methylated in lymph node metastases of breast cancers

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Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation.

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Urinary levels of Bcl-2 are elevated in ovarian cancer patients

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Urinary mesothelin provides greater sensitivity for early stage ovarian cancer than serum mesothelin, urinary hCG free beta subunit and urinary hCG beta core fragment

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Use of Biomarkers to Guide Decisions on Adjuvant Systemic Therapy for Women With Early-Stage Invasive Breast Cancer: ASCO Clinical Practice Guideline Update-Integration of Results From TAILORx

scientific article published on 31 May 2019

Use of Biomarkers to Guide Decisions on Adjuvant Systemic Therapy for Women With Early-Stage Invasive Breast Cancer: American Society of Clinical Oncology Clinical Practice Guideline

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Use of Biomarkers to Guide Decisions on Adjuvant Systemic Therapy for Women With Early-Stage Invasive Breast Cancer: American Society of Clinical Oncology Clinical Practice Guideline Focused Update

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Use of Biomarkers to Guide Decisions on Systemic Therapy for Women With Metastatic Breast Cancer: American Society of Clinical Oncology Clinical Practice Guideline

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Use of CA-125 in clinical trial evaluation of new therapeutic drugs for ovarian cancer

scientific article published on June 2004

Use of Ras-transformed human ovarian surface epithelial cells as a model for studying ovarian cancer

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Use of the CA 125 antigen in diagnosis and monitoring of ovarian carcinoma

Utility of a novel serum tumor biomarker HE4 in patients with endometrioid adenocarcinoma of the uterus

scientific article published on 21 May 2008

Validation of a Biomarker Panel and Longitudinal Biomarker Performance for Early Detection of Ovarian Cancer

scientific article published on 20 May 2016

Validation of a Novel Biomarker Panel for the Detection of Ovarian Cancer

scientific article published on 22 July 2016

Weight Loss Upregulates the Small GTPase DIRAS3 in Human White Adipose Progenitor Cells, Which Negatively Regulates Adipogenesis and Activates Autophagy via Akt-mTOR Inhibition

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p53 overexpression in formalin-fixed, paraffin-embedded tissue detected by immunohistochemistry

scientific article published on 01 July 1992

p53-Based Gene Therapy of Ovarian Cancer: Magic Bullet? ⬇️

scientific article published on November 1, 1995

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