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List of works by Tim M. Illidge

4 Gy versus 24 Gy radiotherapy for patients with indolent lymphoma (FORT): a randomised phase 3 non-inferiority trial.

scientific article published on 24 February 2014

944OBRENTUXIMAB VEDOTIN IN COMBINATION WITH CHP IN PATIENTS (PTS) WITH NEWLY-DIAGNOSED CD30+ PERIPHERAL T-CELL LYMPHOMAS (PTCL): 2-YEAR FOLLOW-UP

scientific article published in September 2014

A New in Vivo and in Vitro B cell Lymphoma Model, π-BCL1

article

A TLR7 agonist enhances the antitumor efficacy of obinutuzumab in murine lymphoma models via NK cells and CD4 T cells

scientific article published on 28 November 2016

A new anti-idiotype antibody capable of binding rituximab on the surface of lymphoma cells

scientific article published on 22 June 2004

A novel systemically administered Toll-like receptor 7 agonist potentiates the effect of ionizing radiation in murine solid tumor models

scientific article

A retrospective analysis of selective internal radiation therapy (SIRT) with yttrium-90 microspheres in patients with unresectable hepatic malignancies

scientific article published on 15 June 2010

A study to investigate dose escalation of doxorubicin in ABVD chemotherapy for Hodgkin lymphoma incorporating biomarkers of response and toxicity

scientific article published on 17 October 2013

Abstract 3042: The novel Akt inhibitor AZD5363 following radiotherapy improves tumor control in mouse models of head and neck cancer

Acquired resistance to fractionated radiotherapy can be overcome by concurrent PD-L1 blockade

scientific article published in October 2014

Akt inhibition improves long-term tumour control following radiotherapy by altering the microenvironment

scientific article published on 30 October 2017

Allogeneic transplant following brentuximab vedotin in patients with relapsed or refractory Hodgkin lymphoma and systemic anaplastic large cell lymphoma.

scientific article

Anti-CD 40 monoclonal antibody.

scientific article

Anti-CD40 monoclonal antibody therapy in combination with irradiation results in a CD8 T-cell-dependent immunity to B-cell lymphoma

scientific article

Anti-Yo antibody-positive cerebellar degeneration associated with endometrial carcinoma: case report and review of the literature.

scientific article

Antibody-induced intracellular signaling works in combination with radiation to eradicate lymphoma in radioimmunotherapy

scientific article published on 23 October 2003

Antibody-induced nonapoptotic cell death in human lymphoma and leukemia cells is mediated through a novel reactive oxygen species-dependent pathway

scientific article

Antitumor Efficacy of Radiation plus Immunotherapy Depends upon Dendritic Cell Activation of Effector CD8+ T Cells

scientific article published on 30 May 2016

Apparent modulation of CD20 by rituximab: an alternative explanation

scientific article

Balancing Risks in Developing a Personalised Approach to the Treatment of Early Hodgkin Lymphoma: Have We Got the Balance Right?

scientific article published on 21 June 2015

Breast cancer risk following Hodgkin lymphoma radiotherapy in relation to menstrual and reproductive factors

scientific article published on 07 May 2013

Brentuximab vedotin (SGN-35) in patients with relapsed or refractory systemic anaplastic large-cell lymphoma: results of a phase II study

scientific article

Brentuximab vedotin in patients with relapsed or refractory Hodgkin lymphoma who are Ineligible for autologous stem cell transplant: A Germany and United Kingdom retrospective study

scientific article published on 26 September 2017

Brentuximab vedotin in refractory CD30+ lymphomas: a bridge to allogeneic transplantation in approximately one quarter of patients treated on a Named Patient Programme at a single UK center

scientific article published on 12 October 2012

Brentuximab vedotin in the front-line treatment of patients with CD30+ peripheral T-cell lymphomas: results of a phase I study

scientific article

British Association of Dermatologists and U.K. Cutaneous Lymphoma Group guidelines for the management of primary cutaneous lymphomas 2018

scientific article published on 17 December 2018

Cervical Neuropathy Following Mantle Radiotherapy

scientific article published on 01 December 2002

Challenging CD30-positive lymphomas--current challenges, new insights and future directions: joining a conversation on CD30+ lymphomas

scientific article published on 23 August 2014

Clinical Development of Novel Drug-Radiotherapy Combinations

scientific article published on 29 November 2018

Clinical development of new drug-radiotherapy combinations ⬇️

scientific article published on June 2016

Clinical efficacy of zanolimumab (HuMax-CD4): two phase 2 studies in refractory cutaneous T-cell lymphoma

scientific article published on 20 February 2007

Clinical quantitation of immune signature in follicular lymphoma by RT-PCR-based gene expression profiling

scientific article published on 03 January 2008

Comment on: "clinical features, management, and prognosis of an international series of 161 patients with limited-stage diffuse large B-cell lymphoma of the bone (the IELSG-14 Study)".

scientific article published in December 2014

Comparisons of dosimetric approaches for fractionated radioimmunotherapy of non-Hodgkin lymphoma

scientific article published on December 1, 2012

Consensus conference: implementing treatment recommendations on yttrium-90 immunotherapy in clinical practice - report of a European workshop

scientific article published on 14 January 2008

Consensus guidelines for the definition, detection and interpretation of immunogenic cell death

scientific article published on 01 March 2020

Consensus guidelines for the detection of immunogenic cell death

scientific article published on October 2014

Current Developments in Specialty Training

scientific article published on 01 July 2011

Current treatment approaches for diffuse large B-cell lymphoma

scientific article published on April 2008

Cyclophosphamide inhibition of anti-CD40 monoclonal antibody-based therapy of B cell lymphoma is dependent on CD11b+ cells

scientific article published in August 2005

Defining a Hodgkin lymphoma population for novel therapeutics after relapse from autologous hematopoietic cell transplant

scientific article published on 5 June 2013

Efficacy and safety of yttrium-90 ibritumomab tiuxetan in patients with relapsed or refractory diffuse large B-cell lymphoma not appropriate for autologous stem-cell transplantation

scientific article published on 26 March 2007

Emerging opportunities for the combination of molecularly targeted drugs with radiotherapy

scientific article published on 04 March 2014

Endopolyploid cells produced after severe genotoxic damage have the potential to repair DNA double strand breaks

scientific article published on 02 September 2003

Endopolyploidy in irradiated p53-deficient tumour cell lines: persistence of cell division activity in giant cells expressing Aurora-B kinase

scientific article

Euthanasia

scientific article published in the British Medical Journal

Evaluation of apoptosis imaging biomarkers in a genetic model of cell death

scientific article published on 19 February 2019

Extranodal diffuse large B-cell lymphoma (DLBCL) and primary mediastinal B-cell lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article published on 04 July 2016

Final results of a multicenter phase II study of the purine nucleoside phosphorylase (PNP) inhibitor forodesine in patients with advanced cutaneous T-cell lymphomas (CTCL) (Mycosis fungoides and Sézary syndrome).

scientific article

Five-Year Outcomes for Frontline Brentuximab Vedotin with CHP for CD30 Expressing Peripheral T-Cell Lymphomas

scientific article published on 5 March 2018

Five-year results of brentuximab vedotin in patients with relapsed or refractory systemic anaplastic large cell lymphoma

scientific article published on 3 October 2017

Fractionated Radiation Therapy Stimulates Antitumor Immunity Mediated by Both Resident and Infiltrating Polyclonal T-cell Populations when Combined with PD-1 Blockade

scientific article published on 22 May 2017

Fractionated ⁹⁰Y-ibritumomab tiuxetan radioimmunotherapy as an initial therapy of follicular lymphoma: an international phase II study in patients requiring treatment according to GELF/BNLI criteria.

scientific article published on 2 December 2013

Fusion of metabolic function and morphology: sequential [18F]fluorodeoxyglucose positron-emission tomography/computed tomography studies yield new insights into the natural history of bone metastases in breast cancer.

scientific article published on 25 June 2007

Guideline on the management of primary resistant and relapsed classical Hodgkin lymphoma

scientific article published on 01 October 2013

Guidelines for preclinical and early phase clinical assessment of novel radiosensitisers

scientific article published on 19 July 2011

Guidelines on the investigation and management of follicular lymphoma

scientific article published on 23 December 2011

Hodgkin lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article published on 01 October 2018

Hodgkin's lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

scientific article

How do we move towards a personalised approach in the treatment of Early Hodgkin lymphoma?

scientific article published on 22 May 2018

How have outcomes for patients with follicular lymphoma changed with the addition of monoclonal antibodies?

scientific article published on July 2008

ILROG Emergency Guidelines for Radiation Therapy of Hematological Malignancies During the COVID-19 Pandemic

scientific article published on 10 April 2020

Immune Checkpoint Inhibitors in Lung Cancer - An Unheralded Opportunity?

scientific article published on 4 January 2017

Immuno-regulatory antibodies for the treatment of cancer

scientific article published on 16 April 2015

Immunogenic potential of irradiated lymphoma cells is enhanced by adjuvant immunotherapy and modulation of local macrophage populations

scientific article published on 18 February 2013

Immunotherapy with radiotherapy in urological malignancies

scientific article

Intravenous administration of the selective toll-like receptor 7 agonist DSR-29133 leads to anti-tumor efficacy in murine solid tumor models which can be potentiated by combination with fractionated radiotherapy

scientific article published on 5 March 2016

Involved Site Radiation Therapy in Adult Lymphomas: An Overview of International Lymphoma Radiation Oncology Group Guidelines

scientific article published on 06 April 2020

Is it time to rethink checkpoint blockade therapy in non-Hodgkin lymphoma?

scientific article published on 18 June 2020

Malignant hypercalcaemia in pregnancy and antenatal administration of intravenous pamidronate

scientific article published on 01 January 1996

Maximum tumor diameter is associated with event-free survival in PET-negative patients with stage I/IIA Hodgkin lymphoma

scientific article published on 01 January 2020

Methodological Considerations in the Evaluation of Radiotherapy Technologies

scientific article published on 12 July 2012

Microscopic Intratumoral Dosimetry of Radiolabeled Antibodies Is a Critical Determinant of Successful Radioimmunotherapy in B-Cell Lymphoma

scientific article published on 01 February 2007

Modern radiation therapy for Hodgkin lymphoma: field and dose guidelines from the international lymphoma radiation oncology group (ILROG).

scientific article published on 18 June 2013

Modern radiation therapy for extranodal lymphomas: field and dose guidelines from the International Lymphoma Radiation Oncology Group

scientific article

Modern radiation therapy for nodal non-Hodgkin lymphoma-target definition and dose guidelines from the International Lymphoma Radiation Oncology Group

scientific article published in May 2014

Modern radiation therapy for primary cutaneous lymphomas: field and dose guidelines from the International Lymphoma Radiation Oncology Group

scientific article published in May 2015

Monoclonal antibody therapy of B cell lymphoma: signaling activity on tumor cells appears more important than recruitment of effectors.

scientific article

New antibody drug treatments for lymphoma

scientific article published on 14 March 2011

New insights into the mechanisms of action of radioimmunotherapy in lymphoma.

scientific article published on August 2008

New opportunities for anti-CD20 monoclonal antibody to give a direct punch to the tumor

scientific article

Novel Methods to Improve the Efficiency of Radioimmunotherapy for Non-Hodgkin Lymphoma

scientific article published on 31 March 2019

Novel type II anti-CD20 monoclonal antibody (GA101) evokes homotypic adhesion and actin-dependent, lysosome-mediated cell death in B-cell malignancies

scientific article

Nuclear envelope-limited chromatin sheets are part of mitotic death

scientific article published on 8 February 2002

Obinutuzumab (GA101) – a different anti-CD20 antibody with great expectations

scientific article published on 20 March 2012

Obinutuzumab in hematologic malignancies: lessons learned to date

scientific article

PET-Directed Therapy for Hodgkin's Lymphoma

scientific article published on 01 July 2015

Patient and physician preferences for first-line treatment of classical Hodgkin lymphoma in Germany, France and the United Kingdom.

scientific article published on 21 September 2018

Pembrolizumab in Combination with Radiotherapy for Metastatic Melanoma - Introducing the PERM Trial.

scientific article published on 2 February 2018

Personalised approach to treating early Hodgkin's lymphoma

scientific article published in the British Medical Journal

Phase 1/2 study of fractionated 131I-rituximab in low-grade B-cell lymphoma: the effect of prior rituximab dosing and tumor burden on subsequent radioimmunotherapy

scientific article published on 12 December 2008

Phase II study of gemcitabine and bexarotene (GEMBEX) in the treatment of cutaneous T-cell lymphoma

scientific article published on 17 October 2013

Polyploid giant cells provide a survival mechanism for p53 mutant cells after DNA damage.

scientific article

Positron Emission Tomography Score Has Greater Prognostic Significance Than Pretreatment Risk Stratification in Early-Stage Hodgkin Lymphoma in the UK RAPID Study

scientific article published on 21 May 2019

Pretreatment Lymphocyte Count Predicts Benefit From Concurrent Chemotherapy With Radiotherapy in Oropharyngeal Cancer

scientific article published in 2022

Radiation therapy planning for early-stage Hodgkin lymphoma: experience of the International Lymphoma Radiation Oncology Group.

scientific article published on 7 February 2015

Radiation therapy with tositumomab (B1) anti-CD20 monoclonal antibody initiates extracellular signal-regulated kinase/mitogen-activated protein kinase-dependent cell death that overcomes resistance to apoptosis

scientific article

Radiation-induced apoptosis

scientific article published on 01 January 1998

Radioimmunotherapy in follicular lymphoma

scientific article published on 12 May 2011

Radioimmunotherapy in the π-BCL1 B cell Lymphoma Model: Efficacy Depends on More Than Targeted Irradiation Alone

article

Radioimmunotherapy of Lymphoma: A Treatment Approach Ahead of Its Time or Past Its Sell-By Date?

scientific article published on 10 May 2010

Radiotherapy Research Priorities for the UK

scientific article published on 02 April 2010

Radiotherapy and Immunotherapy Combinations in Non-small Cell Lung Cancer: A Promising Future?

scientific article published on 9 August 2016

Radiotherapy and anti-PD-1/PD-L1 combinations in lung cancer: building better translational research platforms

scientific article

Radiotherapy physics research in the UK: challenges and proposed solutions.

scientific article

Real-world effectiveness of brentuximab vedotin versus physicians' choice chemotherapy in patients with relapsed/refractory Hodgkin lymphoma following autologous stem cell transplantation in the United Kingdom and Germany

scientific article

Recommendations for the clinical management of the elderly patient with malignant lymphoma.

scientific article published on 19 January 2018

Recommendations for the use of yttrium-90 ibritumomab tiuxetan in malignant lymphoma.

scientific article published on August 2006

Reduced dose radiotherapy for local control in non-Hodgkin lymphoma: A randomised phase III trial

scientific article published on 12 June 2011

Release of mitotic descendants by giant cells from irradiated Burkitt's lymphoma cell line..

scientific article published on January 2000

Reprogramming the tumour microenvironment by radiotherapy: implications for radiotherapy and immunotherapy combinations

scientific article published on 04 November 2020

Results of a trial of PET-directed therapy for early-stage Hodgkin's lymphoma

scientific article published in April 2015

Revisiting the role of radiotherapy in Hodgkin lymphoma to augment systemic immunity

scientific article published on 22 June 2018

Role of Radiation Therapy in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma: Guidelines from the International Lymphoma Radiation Oncology Group.

scientific article published in March 2018

Segregation of genomes in polyploid tumour cells following mitotic catastrophe.

scientific article

Short duration immunochemotherapy followed by radioimmunotherapy consolidation is effective and well tolerated in relapsed follicular lymphoma: 5-year results from a UK National Cancer Research Institute Lymphoma Group study.

scientific article published on 05 February 2016

Stereotactic ablative radiotherapy and immunotherapy combinations: turning the future into systemic therapy?

scientific article published on 24 August 2016

Sustained tumour eradication after induced caspase-3 activation and synchronous tumour apoptosis requires an intact host immune response

scientific article published on 15 February 2013

Synchronous apoptosis in established tumors leads to the induction of adaptive immunity

scientific article published on 16 April 2013

Systemic delivery of a TLR7 agonist in combination with radiation primes durable antitumor immune responses in mouse models of lymphoma

scientific article published on 18 October 2012

The ECHELON-2 Trial: 5-year results of a randomized, phase III study of brentuximab vedotin with chemotherapy for CD30-positive peripheral T-cell lymphoma

The Junior Radiology Forum: What do the trainees think about the future of oncology training?

scientific article published on 01 January 1998

The Role of Radiation Therapy in Patients With Relapsed or Refractory Hodgkin Lymphoma: Guidelines From the International Lymphoma Radiation Oncology Group

scientific article published on 9 January 2018

The abscopal effect of local radiotherapy: using immunotherapy to make a rare event clinically relevant

scientific article

The anti-PD-1 era - an opportunity to enhance radiotherapy for patients with bladder cancer

scientific article published on 31 October 2017

The anti-tumor immune response generated by radiation therapy may be limited by tumor cell adaptive resistance and can be circumvented by PD-L1 blockade

The antitumor immune response generated by fractionated radiation therapy may be limited by tumor cell adaptive resistance and can be circumvented by PD-L1 blockade

scientific article

The effect of hypoxia on PD-L1 expression in bladder cancer

scientific article published on 25 November 2021

The future of anti-CD20 monoclonal antibodies: are we making progress?

scientific article published on 05 January 2011

The future of oncology training: from the trainees' perspective

scientific article published on January 1998

The importance of antibody-specificity in determining successful radioimmunotherapy of B-cell lymphoma

article

The induction of immunogenic cell death by type II anti-CD20 monoclonal antibodies has mechanistic differences compared with type I rituximab

scientific article published on 18 June 2013

The influence of radiation in the context of developing combination immunotherapies in cancer

scientific article published on 01 December 2017

The management of primary mediastinal B-cell lymphoma: a British Society for Haematology Good Practice Paper

scientific article published on 04 January 2019

Tumor cell embryonality and the ploidy number 32n: is it a developmental checkpoint?

scientific article published in June 2011

Turning Radiotherapy into an Effective Systemic Anti-cancer Treatment in Combination with Immunotherapy

scientific article published on 26 September 2015

U.K. consensus statement on safe clinical prescribing of bexarotene for patients with cutaneous T-cell lymphoma

scientific article published on 03 December 2012

Update on obinutuzumab in the treatment of B-cell malignancies

scientific article published on 05 September 2014

Validation of an ELISA for the determination of rituximab pharmacokinetics in clinical trials subjects

scientific article published on 11 June 2010

When is a predose a dose too much?

scientific article published on 01 June 2009

XVII. Radiotherapy in early stage Hodgkin lymphoma

scientific article published on June 2013

YY1 expression predicts favourable outcome in follicular lymphoma

scientific article published on 25 November 2010

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