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List of works by Silja Wessler

A constituent of green tea, epigallocatechin-3-gallate, activates endothelial nitric oxide synthase by a phosphatidylinositol-3-OH-kinase-, cAMP-dependent protein kinase-, and Akt-dependent pathway and leads to endothelial-dependent vasorelaxation

scientific article

A novel basolateral type IV secretion model for the CagA oncoprotein of Helicobacter pylori

scientific article published on 9 December 2017

Abl family of tyrosine kinases and microbial pathogenesis

scientific article published on January 2011

Activation of activator protein 1 and stress response kinases in epithelial cells colonized by Helicobacter pylori encoding the cag pathogenicity island.

scientific article published in October 1999

Activity and Functional Importance of Helicobacter pylori Virulence Factors.

scientific article published on 24 April 2019

Analysis of the type IV secretion system-dependent cell motility of Helicobacter pylori-infected epithelial cells

scientific article published in September 2004

Autoregulation of human relaxin-2 gene expression critically involves relaxin and glucocorticoid receptor binding to glucocorticoid response half-sites in the relaxin-2 promoter

scientific article published on 14 March 2009

B-Raf/Rap1 signaling, but not c-Raf-1/Ras, induces the histidine decarboxylase promoter in Helicobacter pylori infection

scientific article published on 14 January 2002

Bacterial serine protease HtrA as a promising new target for antimicrobial therapy?

scientific article published on 10 January 2017

CagA Phosphorylation in Helicobacter pylori-Infected B Cells Is Mediated by the Nonreceptor Tyrosine Kinases of the Src and Abl Families

scientific article published on 05 July 2016

CagA-independent disruption of adherence junction complexes involves E-cadherin shedding and implies multiple steps in Helicobacter pylori pathogenicity

scientific article published on 24 July 2007

Calcium binding protects E-cadherin from cleavage by Helicobacter pylori HtrA.

scientific article published on 6 June 2016

Carnobacterium divergens - a dominating bacterium of pork meat juice

scientific article

Characterisation of worldwide Helicobacter pylori strains reveals genetic conservation and essentiality of serine protease HtrA.

scientific article published on 16 November 2015

Cloning, Purification and Characterization of the Collagenase ColA Expressed by Bacillus cereus ATCC 14579

scientific article

Complex cellular responses of Helicobacter pylori-colonized gastric adenocarcinoma cells

scientific article

Context-based identification of protein-protein interfaces and "hot-spot" residues

scientific article published in March 2011

Differential gene expression in ERα-positive and ERα-negative breast cancer cells upon leptin stimulation

scientific article published on 15 February 2013

Differential phosphoproteome profiling reveals a functional role for VASP in Helicobacter pylori-induced cytoskeleton turnover in gastric epithelial cells

scientific article

Distinct roles of secreted HtrA proteases from gram-negative pathogens in cleaving the junctional protein and tumor suppressor E-cadherin

scientific article published on 15 February 2012

Emerging roles of Abl family tyrosine kinases in microbial pathogenesis

scientific article published on 07 January 2008

Exploiting the Gastric Epithelial Barrier: Helicobacter pylori's Attack on Tight and Adherens Junctions

scientific article published on January 2017

Expression of estrogen receptor alpha increases leptin-induced STAT3 activity in breast cancer cells

scientific article published on July 2010

Extracellular HtrA serine proteases: An emerging new strategy in bacterial pathogenesis.

scientific article published on 26 March 2018

Extracellular secretion of protease HtrA from Campylobacter jejuni is highly efficient and independent of its protease activity and flagellum

scientific article published on 23 September 2013

Fragment-Based De Novo Design Reveals a Small-Molecule Inhibitor of Helicobacter Pylori HtrA.

scientific article published on 9 June 2015

From Virtual Screening to Bioactive Compounds by Visualizing and Clustering of Chemical Space

scholarly article by Alexander Klenner et al published 30 November 2011 in Molecular Informatics

From inflammation to gastric cancer - the importance of Hedgehog/GLI signaling in Helicobacter pylori-induced chronic inflammatory and neoplastic diseases

scientific article

Helicobacter exploits integrin for type IV secretion and kinase activation

scientific article

Helicobacter pylori Employs a Unique Basolateral Type IV Secretion Mechanism for CagA Delivery

scientific article

Helicobacter pylori HtrA is a new secreted virulence factor that cleaves E-cadherin to disrupt intercellular adhesion

scientific article published on 3 September 2010

Helicobacter pylori activates protein kinase C delta to control Raf in MAP kinase signalling: role in AGS epithelial cell scattering and elongation

scientific article

Helicobacter pylori activates the histidine decarboxylase promoter through a mitogen-activated protein kinase pathway independent of pathogenicity island-encoded virulence factors

scientific article

Helicobacter pylori stimulates host cyclooxygenase-2 gene transcription: critical importance of MEK/ERK-dependent activation of USF1/-2 and CREB transcription factors

scientific article published in November 2003

Helicobacter pylori stimulates host vascular endothelial growth factor-A (vegf-A) gene expression via MEK/ERK-dependent activation of Sp1 and Sp3.

scientific article published on 3 November 2003

Helicobacter pylori-Derived Outer Membrane Vesicles (OMVs): Role in Bacterial Pathogenesis?

scientific article published on 31 August 2020

Helicobacter pylori-controlled c-Abl localization promotes cell migration and limits apoptosis

scientific article published on 31 January 2019

Helicobacter pyloriCagL dependent induction of gastrin expression via a novel αvβ5-integrin–integrin linked kinase signalling complex

article by Tobias Wiedemann et al published 27 January 2012 in Gut

HtrA-mediated E-cadherin cleavage is limited to DegP and DegQ homologs expressed by gram-negative pathogens ⬇️

scientific article published on 08 December 2016

Hybrid Network Model for "Deep Learning" of Chemical Data: Application to Antimicrobial Peptides

scientific article

Identification of Desmoglein-2 as a novel target of Helicobacter pylori HtrA in epithelial cells

scientific article published on 06 November 2021

Identification of E-cadherin signature motifs functioning as cleavage sites for Helicobacter pylori HtrA

scientific article

Identification of estrogen receptor ligands leading to activation of non-genomic signaling pathways while exhibiting only weak transcriptional activity

scientific article published on 3 October 2005

Inhibiting Helicobacter pylori HtrA protease by addressing a computationally predicted allosteric ligand binding site

scientific article

Inhibitors of Helicobacter pylori protease HtrA found by 'virtual ligand' screening combat bacterial invasion of epithelia

scientific article

Many ways of communication: from Helicobacter pylori adherence to death, disruption, migration and escape ⬇️

scientific article published on November 1, 2011

Molecular mechanisms of epithelial-barrier disruption by Helicobacter pylori

scientific article published on 09 July 2008

Multi-Approach Analysis for the Identification of Proteases within Birch Pollen

scientific article published on 4 July 2017

Nanomaterial–microbe cross-talk: physicochemical principles and (patho)biological consequences

scientific article published on 01 July 2018

Nanoparticle binding attenuates the pathobiology of gastric cancer-associated Helicobacter pylori

scientific article

Nanosized food additives impact beneficial and pathogenic bacteria in the human gut: a simulated gastrointestinal study

scientific article published on 04 December 2018

Neisseria gonorrhoeae epithelial cell interaction leads to the activation of the transcription factors nuclear factor kappaB and activator protein 1 and the induction of inflammatory cytokines

scientific article published on July 1997

Oxidative Phosphorylation System in Gastric Carcinomas and Gastritis

scientific article

Peptide-Membrane Interaction between Targeting and Lysis

scientific article published in August 2017

Peroxiredoxin 6 promotes upregulation of the prion protein (PrP) in neuronal cells of prion-infected mice

scientific article published on 4 December 2012

Phosphorylation of Helicobacter pylori CagA by c-Abl leads to cell motility

scientific article published on 11 December 2006

Piloting the membranolytic activities of peptides with a self-organizing map.

scientific article published on 9 September 2014

Prediction of extracellular proteases of the human pathogen Helicobacter pylori reveals proteolytic activity of the Hp1018/19 protein HtrA

scientific article

Proteolysis in Helicobacter pylori-Induced Gastric Cancer ⬇️

scientific article published on 11 April 2017

Proteolytic Activities Expressed by Gastrointestinal Pathogens Bacillus cereus, Listeria monocytogenes and Enterococcus faecium in Different Growth Phases

scientific article published on February 2015

Quantitative phosphoproteomic analysis of prion-infected neuronal cells

scientific article published on 28 September 2010

Rapid paracellular transmigration of Campylobacter jejuni across polarized epithelial cells without affecting TER: role of proteolytic-active HtrA cleaving E-cadherin but not fibronectin

scientific article published on 25 April 2012

Rational Design of Membrane-Pore-Forming Peptides

scientific article

Regulation of the actin cytoskeleton in Helicobacter pylori-induced migration and invasive growth of gastric epithelial cells ⬇️

scientific article published on November 1, 2011

Role of the cag-pathogenicity island encoded type IV secretion system in Helicobacter pylori pathogenesis

scientific article

Serine phosphorylation of cortactin controls focal adhesion kinase activity and cell scattering induced by Helicobacter pylori

scientific article published in June 2011

Sparse Neural Network Models of Antimicrobial Peptide-Activity Relationships

scientific article published on 11 July 2016

Special Issue "H. pylori Virulence Factors in the Induction of Gastric Cancer". ⬇️

scientific article published on 26 April 2018

TLR2, TLR4 and TLR10 Shape the Cytokine and Chemokine Release of H. pylori-Infected Human DCs

scientific article published on 29 May 2020

Targeting focal adhesions:Helicobacter pylori-host communication in cell migration

scientific article published on 06 August 2008

The anti-inflammatory compound curcumin inhibits Neisseria gonorrhoeae-induced NF-kappaB signaling, release of pro-inflammatory cytokines/chemokines and attenuates adhesion in late infection

scientific article published in May 2005

The functional interplay of Helicobacter pylori factors with gastric epithelial cells induces a multi-step process in pathogenesis

scientific article published on 07 October 2013

The proteolytic activity of Listeria monocytogenes HtrA

scientific article published on 14 November 2019

The sound of tumor cell-microenvironment communication - composed by the Cancer Cluster Salzburg research network

scientific article published on 2 June 2017

The stability and activity of recombinant Helicobacter pylori HtrA under stress conditions

scientific article published on 26 June 2012

Transmigration route of Campylobacter jejuni across polarized intestinal epithelial cells: paracellular, transcellular or both?

scientific article published on 30 September 2013

Tyrosine Kinases in Helicobacter pylori Infections and Gastric Cancer

scientific article published on 11 October 2019

c-Src and c-Abl kinases control hierarchic phosphorylation and function of the CagA effector protein in Western and East Asian Helicobacter pylori strains

scientific article published in March 2012

p120 and Kaiso regulate Helicobacter pylori-induced expression of matrix metalloproteinase-7.

scientific article published on 23 July 2008

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