List of works - Luke Leenen

A Proposal for an Intermediate Care Unit-Quality Measurement Framework.

scientific article published on 29 July 2018

A cohort study to evaluate infection prevention protocol in pediatric trauma patients with blunt splenic injury in a Dutch level 1 trauma center

scientific article published on 28 August 2018

A rare type of ankle fracture: Syndesmotic rupture combined with a high fibular fracture without medial injury

scientific article published on 18 January 2016

A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1.

scientific article published on 12 December 2011

Abdominal trauma: from operative to nonoperative management

scientific article published on 01 November 2009

Aberrant regulation of polymorphonuclear phagocyte responsiveness in multitrauma patients

scientific article published on 01 December 2006

Accuracy of different survival prediction models in a trauma population

scientific article published on 19 August 2010

Applicability of the trimodal distribution of trauma deaths in a Level I trauma centre in the Netherlands with a population of mainly blunt trauma

scientific article published on 25 July 2008

Are current wireless monitoring systems capable of detecting adverse events in high-risk surgical patients? A descriptive study

scientific article published on 17 November 2019

Associations of the Emergency Severity Index triage categories with patients' vital signs at triage: a prospective observational study

scientific article published on 15 November 2010

Base deficit-based predictive modeling of outcome in trauma patients admitted to intensive care units in Dutch trauma centers

scientific article published on 01 October 2007

Blunt traumatic carotid artery dissection still a pitfall? The rationale for aggressive screening

scientific article published on 13 July 2010

C1-esterase inhibitor attenuates the inflammatory response during human endotoxemia.

scientific article published in November 2010

Comparing fracture healing disorders and long-term functional outcome of polytrauma patients and patients with an isolated displaced midshaft clavicle fracture

scientific article published on 09 August 2016

Comparison between the prognostic value of the white blood cell differential count and morphological parameters of neutrophils and lymphocytes in severely injured patients for 7-day in-hospital mortality

scientific article published on 24 September 2012

Compliance to prehospital trauma triage protocols worldwide: A systematic review

scientific article published on 03 July 2018

Diagnostic value of emergency medical services provider judgement in the identification of head injuries among trauma patients

scientific article published on 30 September 2018

Differential antibacterial control by neutrophil subsets

scientific article published on 01 June 2018

Do designated trauma systems improve outcome?

scientific article published on December 2007

Does thoracic injury impair the predictive value of base deficit in trauma patients?

scientific article published on 26 April 2010

Editorial Comment

scientific article published on 01 October 2012

Effects of the application of a checklist during trauma resuscitations on ATLS adherence, team performance, and patient-related outcomes: a systematic review

scientific article published on 07 August 2019

Evaluation of admissions to the Major Incident Hospital based on a standardized protocol

scientific article

Evaluation of hematological parameters on admission for the prediction of 7-day in-hospital mortality in a large trauma cohort

scientific article published on 31 January 2011

Evaluation of trauma care in a mature level I trauma center in the Netherlands: outcomes in a Dutch mature level I trauma center.

scientific article published in October 2013

Functional heterogeneity and differential priming of circulating neutrophils in human experimental endotoxemia

scientific article published on 16 April 2010

Functional outcomes of traumatic midfoot injuries

scientific article published on 12 September 2018

Getting it right first time: The importance of a structured tissue sampling protocol for diagnosing fracture-related infections

scientific article published on 07 June 2019

Health-related quality of life in trauma patients who sustained a calcaneal fracture.

scientific article

Hemodynamic support of the trauma patient.

scientific article published on April 2010

Historic overview of treatment techniques for rib fractures and flail chest ⬇️

scientific article (publication date: October 2010)

History, development and future of trauma care for multiple injured patients in the Netherlands

scientific article published on 13 September 2012

Homology in systemic neutrophil response induced by human experimental endotoxemia and by trauma

scientific article published on 01 February 2012

Immunophenotyping of posttraumatic neutrophils on a routine haematology analyser

scientific article

Immunotherapy after trauma: timing is essential.

scientific article published on April 2011

Increased consumption of hospital resources due to complications: an assessment of costs in a level I trauma center

scientific article published on 01 November 2011

Intramedullary Fixation Versus Plate Fixation of Distal Fibular Fractures: A Systematic Review and Meta-Analysis of Randomized Controlled Trials and Observational Studies

scientific article published on 01 January 2019

Intramedullary nailing of the femur and the systemic activation of monocytes and neutrophils

scientific article published on 31 October 2011

Intramedullary nailing without interlocking screws for femoral and tibial shaft fractures.

scientific article

Introducing the Surgical Therapeutic Index in trauma surgery: an assessment tool for the benefits and risks of operative fracture treatment strategies.

scientific article published on 8 August 2016

Isolated blunt chest injury leads to transient activation of circulating neutrophils ⬇️

scientific article published on July 27, 2010

Isolated hip fracture care in an inclusive trauma system: A trauma system wide evaluation

scientific article published on 25 February 2015

Kinetics of the innate immune response after trauma: implications for the development of late onset sepsis.

scientific article published in July 2013

Long-term quality of life after surgical intensive care admission

scientific article published on 20 December 2010

Long-term survival after surgical intensive care unit admission: fifty percent die within 10 years

scientific article published in January 2011

Major Incident Hospital: Development of a Permanent Facility for Management of Incident Casualties

scientific article

Management strategies and outcome of blunt traumatic abdominal wall defects: a single centre experience

scientific article published on 26 June 2019

Mass Casualty Event During a Musical Parade: Lessons Learned

scientific article

Mechanical ventilation increases the inflammatory response induced by lung contusion

scientific article published on 22 January 2013

Mechanical ventilation is the determining factor in inducing an inflammatory response in a hemorrhagic shock model

scientific article published on 30 October 2012

Modulation of the innate immune response after trauma visualised by a change in functional PMN phenotype

scientific article published on 31 March 2009

Mortality decreases by implementing a level I trauma center in a Dutch hospital

scientific article published in November 2010

Neutrophils contribute to fracture healing by synthesizing fibronectin+ extracellular matrix rapidly after injury

scientific article published on 12 February 2016

Pelvic Fractures: Soft Tissue Trauma

scientific article published on 31 March 2010

Persistent Inflammation, Immunosuppression and Catabolism Syndrome (PICS) after Polytrauma: A Rare Syndrome with Major Consequences

scientific article published on 10 January 2020

Pitfalls in gastrointestinal permeability measurement in ICU patients

scientific article published on 6 July 2007

Pneumocephalus Following Severe Head Trauma

scientific article published on 30 September 2008

Postinjury immune monitoring: can multiple organ failure be predicted?

scientific article published on December 2008

Posttraumatic immune response and its modulation.

scientific article published on 27 March 2012

Prediction models for complications in trauma patients

scientific article published on 04 April 2011

Pseudarthrosis of the ribs treated with a locking compression plate. A report of three cases

scientific article

Recognizing the mobilization of neutrophils with banded nuclei early after trauma

scientific article published on 06 July 2020

Regional trauma system reduces mortality and changes admission rates: a before and after study

scientific article

Response to "Benefit of Helicopter Emergency Medical Services on trauma patient mortality in the Netherlands?".

scientific article published on 19 August 2012

Severely injured patients benefit from in-house attending trauma surgeons

scientific article published on 10 August 2018

Special Issue on rib fixation ⬇️

scientific article published on September 22, 2010

Systematic review shows lowered risk of nonunion after reamed nailing in patients with closed tibial shaft fractures.

scientific article

Systemic inflammation and fracture healing

scientific article published on 04 January 2011

The ICI classification for calcaneal injuries: a validation study

scientific article

The effect of C1-esterase inhibitor on systemic inflammation in trauma patients with a femur fracture - The CAESAR study: study protocol for a randomized controlled trial

scientific article published on 11 October 2011

The effect of Helicopter Emergency Medical Services on trauma patient mortality in the Netherlands

scientific article published on 2 February 2012

The effects of regionalization of pediatric trauma care in the Netherlands: a surveillance-based before-after study

scientific article published in November 2012

The systemic inflammatory response induced by trauma is reflected by multiple phenotypes of blood neutrophils.

scientific article published on 03 December 2007

Tissue-interface pressures on three different support-surfaces for trauma patients

scientific article published in August 2005

Traumatic hemipelvectomy: Improvements in the last decennia illustrated by 2 case reports

scientific article published on 16 March 2012

Utilisation of Intermediate Care Units: A Systematic Review.

scientific article published on 09 July 2017

Validation of the Thorax Trauma Severity Score for mortality and its value for the development of acute respiratory distress syndrome.

scientific article published on 23 August 2011

List of works by Luke Leenen

A Proposal for an Intermediate Care Unit-Quality Measurement Framework.

A cohort study to evaluate infection prevention protocol in pediatric trauma patients with blunt splenic injury in a Dutch level 1 trauma center

A rare type of ankle fracture: Syndesmotic rupture combined with a high fibular fracture without medial injury

A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1.

Abdominal trauma: from operative to nonoperative management

Aberrant regulation of polymorphonuclear phagocyte responsiveness in multitrauma patients

Accuracy of different survival prediction models in a trauma population

Applicability of the trimodal distribution of trauma deaths in a Level I trauma centre in the Netherlands with a population of mainly blunt trauma

Are current wireless monitoring systems capable of detecting adverse events in high-risk surgical patients? A descriptive study

Associations of the Emergency Severity Index triage categories with patients' vital signs at triage: a prospective observational study

Base deficit-based predictive modeling of outcome in trauma patients admitted to intensive care units in Dutch trauma centers

Blunt traumatic carotid artery dissection still a pitfall? The rationale for aggressive screening

C1-esterase inhibitor attenuates the inflammatory response during human endotoxemia.

Comparing fracture healing disorders and long-term functional outcome of polytrauma patients and patients with an isolated displaced midshaft clavicle fracture

Comparison between the prognostic value of the white blood cell differential count and morphological parameters of neutrophils and lymphocytes in severely injured patients for 7-day in-hospital mortality

Compliance to prehospital trauma triage protocols worldwide: A systematic review

Diagnostic value of emergency medical services provider judgement in the identification of head injuries among trauma patients

Differential antibacterial control by neutrophil subsets

Do designated trauma systems improve outcome?

Does thoracic injury impair the predictive value of base deficit in trauma patients?

Editorial Comment

Effects of the application of a checklist during trauma resuscitations on ATLS adherence, team performance, and patient-related outcomes: a systematic review

Evaluation of admissions to the Major Incident Hospital based on a standardized protocol

Evaluation of hematological parameters on admission for the prediction of 7-day in-hospital mortality in a large trauma cohort

Evaluation of trauma care in a mature level I trauma center in the Netherlands: outcomes in a Dutch mature level I trauma center.

Functional heterogeneity and differential priming of circulating neutrophils in human experimental endotoxemia

Functional outcomes of traumatic midfoot injuries

Getting it right first time: The importance of a structured tissue sampling protocol for diagnosing fracture-related infections

Health-related quality of life in trauma patients who sustained a calcaneal fracture.

Hemodynamic support of the trauma patient.

Historic overview of treatment techniques for rib fractures and flail chest ⬇️

History, development and future of trauma care for multiple injured patients in the Netherlands

Homology in systemic neutrophil response induced by human experimental endotoxemia and by trauma

Immunophenotyping of posttraumatic neutrophils on a routine haematology analyser

Immunotherapy after trauma: timing is essential.

Increased consumption of hospital resources due to complications: an assessment of costs in a level I trauma center

Intramedullary Fixation Versus Plate Fixation of Distal Fibular Fractures: A Systematic Review and Meta-Analysis of Randomized Controlled Trials and Observational Studies

Intramedullary nailing of the femur and the systemic activation of monocytes and neutrophils

Intramedullary nailing without interlocking screws for femoral and tibial shaft fractures.

Introducing the Surgical Therapeutic Index in trauma surgery: an assessment tool for the benefits and risks of operative fracture treatment strategies.

Isolated blunt chest injury leads to transient activation of circulating neutrophils ⬇️

Isolated hip fracture care in an inclusive trauma system: A trauma system wide evaluation

Kinetics of the innate immune response after trauma: implications for the development of late onset sepsis.

Long-term quality of life after surgical intensive care admission

Long-term survival after surgical intensive care unit admission: fifty percent die within 10 years

Major Incident Hospital: Development of a Permanent Facility for Management of Incident Casualties

Management strategies and outcome of blunt traumatic abdominal wall defects: a single centre experience

Mass Casualty Event During a Musical Parade: Lessons Learned

Mechanical ventilation increases the inflammatory response induced by lung contusion

Mechanical ventilation is the determining factor in inducing an inflammatory response in a hemorrhagic shock model

Modulation of the innate immune response after trauma visualised by a change in functional PMN phenotype

Mortality decreases by implementing a level I trauma center in a Dutch hospital

Neutrophils contribute to fracture healing by synthesizing fibronectin+ extracellular matrix rapidly after injury

Pelvic Fractures: Soft Tissue Trauma

Persistent Inflammation, Immunosuppression and Catabolism Syndrome (PICS) after Polytrauma: A Rare Syndrome with Major Consequences

Pitfalls in gastrointestinal permeability measurement in ICU patients

Pneumocephalus Following Severe Head Trauma

Postinjury immune monitoring: can multiple organ failure be predicted?

Posttraumatic immune response and its modulation.

Prediction models for complications in trauma patients

Pseudarthrosis of the ribs treated with a locking compression plate. A report of three cases

Recognizing the mobilization of neutrophils with banded nuclei early after trauma

Regional trauma system reduces mortality and changes admission rates: a before and after study

Response to "Benefit of Helicopter Emergency Medical Services on trauma patient mortality in the Netherlands?".

Severely injured patients benefit from in-house attending trauma surgeons

Special Issue on rib fixation ⬇️

Systematic review shows lowered risk of nonunion after reamed nailing in patients with closed tibial shaft fractures.

Systemic inflammation and fracture healing

The ICI classification for calcaneal injuries: a validation study

The effect of C1-esterase inhibitor on systemic inflammation in trauma patients with a femur fracture - The CAESAR study: study protocol for a randomized controlled trial

The effect of Helicopter Emergency Medical Services on trauma patient mortality in the Netherlands

The effects of regionalization of pediatric trauma care in the Netherlands: a surveillance-based before-after study

The systemic inflammatory response induced by trauma is reflected by multiple phenotypes of blood neutrophils.

Tissue-interface pressures on three different support-surfaces for trauma patients

Traumatic hemipelvectomy: Improvements in the last decennia illustrated by 2 case reports

Utilisation of Intermediate Care Units: A Systematic Review.

Validation of the Thorax Trauma Severity Score for mortality and its value for the development of acute respiratory distress syndrome.