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List of works by Fabio Marra

4-Hydroxynonenal as a selective pro-fibrogenic stimulus for activated human hepatic stellate cells

scientific article published on January 2004

A Large Rheumatoid Nodule Mimicking Hepatic Malignancy

scientific article published on 08 February 2019

A nuclear protein in mesangial cells that binds to the promoter region of the platelet-derived growth factor-A chain gene. Induction by phorbol ester

scientific article published on March 1995

ADMA correlates with portal pressure in patients with compensated cirrhosis.

scientific article published in June 2007

AQP3 is regulated by PPARγ and JNK in hepatic stellate cells carrying PNPLA3 I148M.

scientific article published on 7 November 2017

Accuracy and reproducibility of transient elastography for the diagnosis of fibrosis in pediatric nonalcoholic steatohepatitis.

scientific article published in August 2008

Activation of p38(MAPK) mediates the angiostatic effect of the chemokine receptor CXCR3-B.

scientific article

Acute viral hepatitis increases liver stiffness values measured by transient elastography

scientific article published on February 2008

Adenosine monophosphate-activated protein kinase modulates the activated phenotype of hepatic stellate cells.

scientific article published in February 2008

Adipokines and redox signaling: impact on fatty liver disease

scientific article published on 05 May 2011

Aggressive gastric carcinoma producing alpha-fetoprotein: a case report and review of the literature.

scientific article published on 30 January 2014

Agonist-specific regulation of monocyte chemoattractant protein-1 expression by cyclooxygenase metabolites in hepatic stellate cells.

scientific article

Ang II Upregulation of the T-Lymphocyte Renin-Angiotensin System Is Amplified by Low-Grade Inflammation in Human Hypertension

scientific article published on 10 March 2011

Angiotensin II upregulates renin-angiotensin system in human isolated T lymphocytes

scientific article published on 3 August 2008

Antifibrogenic effects of canrenone, an antialdosteronic drug, on human hepatic stellate cells

scientific article

Assessment of liver fibrosis in primary biliary cholangitis: Comparison between indirect serum markers and fibrosis morphometry

scientific article published on 4 November 2015

Bioadhesive monolayer film for the in vitro transdermal delivery of sumatriptan.

scientific article published in July 2006

CD14+CD34 low Cells With Stem Cell Phenotypic and Functional Features Are the Major Source of Circulating Endothelial Progenitors

scientific article published on 14 July 2005

CXCR3 and alphaEbeta7 integrin identify a subset of CD8+ mature thymocytes that share phenotypic and functional properties with CD8+ gut intraepithelial lymphocytes

scientific article published on 20 December 2005

Challenges of advanced hepatocellular carcinoma

scientific article

Characterization and regulation of the latent transforming growth factor-beta complex secreted by vascular pericytes

scientific article published on 01 March 1996

Comparison of the effects of torasemide and furosemide in nonazotemic cirrhotic patients with ascites: A randomized, double-blind study

scientific article published on 01 June 1991

Complications of cirrhosis: is endothelium guilty?

scientific article published on 01 March 1999

Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells

scientific article

Cultured human liver fat-storing cells produce monocyte chemotactic protein-1. Regulation by proinflammatory cytokines.

scientific article

Curcumin limits the fibrogenic evolution of experimental steatohepatitis.

scientific article

Dendrosomal curcumin nanoformulation downregulates pluripotency genes via miR-145 activation in U87MG glioblastoma cells

scientific article published on 13 January 2014

Differential effect of oleic and palmitic acid on lipid accumulation and apoptosis in cultured hepatocytes

scientific article

Differential requirement of members of the MAPK family for CCL2 expression by hepatic stellate cells.

scientific article published on 11 March 2004

Dose dependent and divergent effects of superoxide anion on cell death, proliferation, and migration of activated human hepatic stellate cells

scientific article published on 24 July 2005

ERK5 differentially regulates PDGF-induced proliferation and migration of hepatic stellate cells

scientific article published on 17 October 2007

Effects of low-dose captopril on renal hemodynamics and function in patients with cirrhosis of the liver

scientific article published on 01 February 1993

Effects of repeated atrial natriuretic peptide bolus injections in cirrhotic patients with refractory ascites

Effects of supplementation with unsaturated fatty acids on plasma and membrane lipid composition and platelet function in patients with cirrhosis and defective aggregation

article

Elastography for the non-invasive assessment of liver disease: limitations and future developments.

scientific article published on February 2009

Elevated plasma levels of urotensin II do not correlate with systemic haemodynamics in patients with cirrhosis.

scientific article published on 12 October 2010

Epidermal growth factor, epidermal growth factor receptor, and transforming growth factor-alpha in human hyperplastic prostate tissue: expression and cellular localization

scientific article published on 01 November 1996

Evaluation of intracellular signalling pathways in response to insulin-like growth factor I in apoptotic-resistant activated human hepatic stellate cells

scientific article published on 30 January 2009

Evaluation of the prognostic value of liver stiffness in patients with hepatitis C virus treated with triple or dual antiviral therapy: A prospective pilot study

scientific article

Expression of platelet-derived growth factor in newly formed cholangiocytes during experimental biliary fibrosis in rats

scientific article published on 01 July 1999

Expression of the thrombin receptor in human liver: Up-regulation during acute and chronic injury

scientific article published on 01 February 1998

Extracellular signal-regulated kinase activation differentially regulates platelet-derived growth factor's actions in hepatic stellate cells, and is induced byIn Vivo liver injury in the rat

scientific article published on 01 October 1999

Extracellular signal-regulated kinases modulate capacitation of human spermatozoa

scientific article published in June 1998

Fibrogenic signalling in hepatic stellate cells.

scientific article

Fibrosis in alcoholic and nonalcoholic steatohepatitis

scientific article published on April 2011

From meetings

Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis

scientific journal article

Ghrelin and fibrogenesis: Relief for a hungry liver ⬇️

scientific article published on February 18, 2011

HIV-1 gp120 signaling through TLR4 modulates innate immune activation in human macrophages and the biology of hepatic stellate cells.

scientific article published on 18 March 2016

Hepatic Notch1 deletion predisposes to diabetes and steatosis via glucose-6-phosphatase and perilipin-5 upregulation

scientific article published on 18 July 2016

Hepatic brucellar abscess

scientific article

Hepatic decompensation is the major driver of death in HCV-infected cirrhotic patients with successfully treated early hepatocellular carcinoma.

scientific article published on 9 February 2017

Hepatocellular carcinoma recurrence in patients with curative resection or ablation: impact of HCV eradication does not depend on the use of interferon

scientific article published on 28 October 2016

Immunomodulation: a new approach to the therapy of cirrhosis?

scientific article published on 01 July 2010

Improved noninvasive prediction of liver fibrosis by liver stiffness measurement in patients with nonalcoholic fatty liver disease accounting for controlled attenuation parameter values.

scientific article published on 17 September 2016

In vitro skin permeation and retention of parabens from cosmetic formulations.

scientific article published in October 2007

Increased phosphorylation of AKAP by inhibition of phosphatidylinositol 3-kinase enhances human sperm motility through tail recruitment of protein kinase A.

scientific article published in March 2004

Induction of Procollagen Type I Gene Expression and Synthesis in Human Hepatic Stellate Cells by 4-Hydroxy-2,3-Nonenal and Other 4-Hydroxy-2,3-Alkenals Is Related to Their Molecular Structure

article

Integrin-mediated stimulation of monocyte chemotactic protein-1 expression

scientific article published in September 1997

Interaction between 4-hydroxy-2,3-alkenals and the platelet-derived growth factor-beta receptor. Reduced tyrosine phosphorylation and downstream signaling in hepatic stellate cells

scientific article published on December 2000

Interferon-gamma-mediated activation of STAT1alpha regulates growth factor-induced mitogenesis.

scientific article published on September 1996

Interferon-inducible protein 10, monokine induced by interferon gamma, and interferon-inducible T-cell alpha chemoattractant are produced by thymic epithelial cells and attract T-cell receptor (TCR) alphabeta+ CD8+ single-positive T cells, [...]

scientific article (publication date: February 2001)

Intracellular reactive oxygen species are required for directional migration of resident and bone marrow-derived hepatic pro-fibrogenic cells.

scientific article

Involvement of phosphatidylinositol 3-kinase in the activation of extracellular signal-regulated kinase by PDGF in hepatic stellate cells

scientific article published on 01 December 1995

Ischemia-reperfusion: The liver under stress

scientific article published on 01 May 1997

LMW-PTP is a negative regulator of insulin-mediated mitotic and metabolic signalling

scientific article published on September 1997

Lack of nitric oxide- and guanosine 3':5'-cyclic monophosphate-dependent regulation of alpha-thrombin-induced calcium transient in endothelial cells of spontaneously hypertensive rat hearts.

scientific article published on August 2000

Leptin and liver fibrosis: A matter of fat

scientific article published on 01 May 2002

Leptin and liver tissue repair: do rodent models provide the answers?

scientific article published on 30 October 2006

Ligands of peroxisome proliferator-activated receptor γ modulate profibrogenic and proinflammatory actions in hepatic stellate cells

scientific article published on 01 August 2000

Lipotoxicity and the gut-liver axis in NASH pathogenesis.

scientific article published on 14 November 2017

Liver fibrosis in the context of nonalcoholic steatohepatitis: the role of adipokines.

scientific article published on 5 September 2017

Liver stiffness correlates with methotrexate cumulative dose in patients with rheumatoid arthritis

scientific article published on 17 September 2011

Liver stiffness is influenced by a standardized meal in patients with chronic hepatitis C virus at different stages of fibrotic evolution

scientific article

Liver stiffness measurement predicts severe portal hypertension in patients with HCV-related cirrhosis

scientific article published on 01 May 2007

Longitudinal assessment of liver stiffness in patients undergoing antiviral treatment for hepatitis C.

scientific article published on 7 May 2013

MARCKS is a downstream effector in platelet-derived growth factor-induced cell motility in activated human hepatic stellate cells

scientific article published on 12 February 2008

MERTK rs4374383 polymorphism affects the severity of fibrosis in non-alcoholic fatty liver disease

scientific article published on 24 October 2015

Mammalian target of rapamycin mediates the angiogenic effects of leptin in human hepatic stellate cells

scientific article published on 20 January 2011

Management strategies for hepatocellular carcinoma: old certainties and new realities.

scientific article

Metabolic disorders across hepatocellular carcinoma in Italy

article

Metronomic capecitabine as second-line treatment for hepatocellular carcinoma after sorafenib discontinuation

scientific article

Modulation of liver fibrosis by adipokines

scientific article published on 30 August 2011

Molecular Pathogenesis of NASH

scientific article

Molecular basis and mechanisms of progression of non-alcoholic steatohepatitis.

scientific article published on 22 January 2008

Molecular mechanisms of hepatic fibrosis in non-alcoholic steatohepatitis.

scientific article published on 07 May 2010

Monocyte chemotactic protein-1 as a chemoattractant for human hepatic stellate cells

scientific article published on 01 January 1999

Monofocal hepatocellular carcinoma: how much does size matter?

scientific article published on 06 November 2020

Myofibroblast - like cells and liver fibrogenesis: Emerging concepts in a rapidly moving scenario.

scientific article published on 07 October 2007

Myostatin regulates the fibrogenic phenotype of hepatic stellate cells via c-jun N-terminal kinase activation

scientific article published on 18 April 2019

NASH limits anti-tumour surveillance in immunotherapy-treated HCC

scientific article published on 24 March 2021

NASH: are genes blowing the hits?

scientific article

NLRP3 inflammasome as a target of berberine in experimental murine liver injury: interference with P2X7 signalling.

scientific article published on 20 July 2016

Nitrovasodilators inhibit platelet-derived growth factor-induced proliferation and migration of activated human hepatic stellate cells

scientific article published on 01 August 2000

Non-invasive assessment of liver fibrosis in patients with HBV-related chronic liver disease undergoing antiviral treatment: A preliminary study.

scientific article

Nonalcoholic fatty liver in nondiabetic patients with acute coronary syndromes.

scientific article

Novel Aspects in the Pathogenesis of Nonalcoholic Steatohepatitis

scientific article published on 21 October 2016

Nuclear factor-kappaB inhibition and non-alcoholic steatohepatitis: inflammation as a target for therapy.

scientific article published in May 2008

Overexpression of Bcl-2 by activated human hepatic stellate cells: resistance to apoptosis as a mechanism of progressive hepatic fibrogenesis in humans.

scientific article published on 19 January 2006

PCSK9 rs11591147 R46L Loss-of-Function Variant Protects Against Liver Damage in Individuals with NAFLD

scientific article published on 22 October 2020

PDGF stimulates tyrosine phosphorylation of JAK 1 protein tyrosine kinase in human mesangial cells

scientific article published on 01 January 1996

PNPLA3 I148M Variant Impairs Liver X Receptor Signaling and Cholesterol Homeostasis in Human Hepatic Stellate Cells

scientific article published on 15 July 2019

Pathophysiology of NASH: Perspectives for a Targeted Treatment ⬇️

scientific article published on January 1, 2013

Patients with advanced hepatocellular carcinoma need a personalized management: A lesson from clinical practice

scientific article published on 21 November 2017

Performance of Doppler ultrasound in the prediction of severe portal hypertension in hepatitis C virus-related chronic liver disease.

scientific article published in December 2007

Pharmacokinetics and pharmacodynamics of torasemide and furosemide in patients with diuretic resistant ascites

scientific article published on 01 October 1996

Phosphatidylinositol 3-kinase inhibition enhances human sperm motility.

scientific article published in September 2001

Phosphatidylinositol 3-kinase is required for platelet-derived growth factor's actions on hepatic stellate cells

scientific article published on 01 April 1997

Phosphatidylinositol-3 kinase and extracellular signal-regulated kinase mediate the chemotactic and mitogenic effects of insulin-like growth factor-I in human hepatic stellate cells

scientific article

Practice guidelines for the diagnosis and management of nonalcoholic fatty liver disease. A decalogue from the Italian Association for the Study of the Liver (AISF) Expert Committee

scientific article published on 19 February 2010

Predictors of survival in patients with established cirrhosis and hepatocellular carcinoma treated with sorafenib.

scientific article published on January 2014

Prevention of severe toxic liver injury and oxidative stress in MCP-1-deficient mice

article

Reliability of transient elastography for the diagnosis of advanced fibrosis in chronic hepatitis C

scientific article published on 30 April 2008

Renaming cytokines: MCP-1, major chemokine in pancreatitis

scientific article

Reply to 'Genetic and clinical data reinforce the role of GAS6 and TAM receptors in liver fibrosis'.

scientific article

Reply to the Letter to the Editor: “Reflection on the unsatisfactory model predicting mortality after TIPS in cirrhotic patients”

scientific article published in 2022

Resistin as an intrahepatic cytokine: overexpression during chronic injury and induction of proinflammatory actions in hepatic stellate cells

scientific article published on December 2006

Restaging patients with hepatocellular carcinoma before additional treatment decisions: a multicenter cohort study

scientific article published on 01 October 2018

Role of Chemokines in the Biology of Cholangiocarcinoma

scientific article published on 07 August 2020

Role of adipocytokines in hepatic fibrosis.

scientific article published on June 2010

Role of the stromal-derived factor-1 (SDF-1)-CXCR4 axis in the interaction between hepatic stellate cells and cholangiocarcinoma

scientific article

Roles for chemokines in liver disease

scientific article

Safety and efficacy of ruxolitinib in splanchnic vein thrombosis associated with myeloproliferative neoplasms.

scientific article published on 23 November 2016

Screening of distress among hospitalized patients in a department of internal medicine.

scientific article published on 25 September 2015

Selective inhibition of NF- B in Kupffer cells: good, but not for everything

scientific article published on 01 December 2009

Serial combination of non-invasive tools improves the diagnostic accuracy of severe liver fibrosis in patients with NAFLD.

scientific article

Signal transduction by the chemokine receptor CXCR3: activation of Ras/ERK, Src, and phosphatidylinositol 3-kinase/Akt controls cell migration and proliferation in human vascular pericytes

scientific article

Silybin, a component of sylimarin, exerts anti-inflammatory and anti-fibrogenic effects on human hepatic stellate cells.

scientific article published on 5 April 2009

Soluble CD163 and mannose receptor as markers of liver disease severity and prognosis in patients with primary biliary cholangitis

scientific article published on 12 April 2020

Super-Resolution Microscopy Reveals an Altered Fibrin Network in Cirrhosis: The Key Role of Oxidative Stress in Fibrinogen Structural Modifications

scientific article published on 12 August 2020

Synthesis, hydrolysis, and skin retention of amino acid esters of alpha-tocopherol.

scientific article published in July 2009

Technology Insight: noninvasive assessment of liver fibrosis by biochemical scores and elastography.

scientific article published on February 2008

The PNPLA3 I148M variant modulates the fibrogenic phenotype of human hepatic stellate cells

scientific article published on 10 January 2017

The Role of Stroma in Cholangiocarcinoma: The Intriguing Interplay between Fibroblastic Component, Immune Cell Subsets and Tumor Epithelium

scientific article published on 22 September 2018

The Src and signal transducers and activators of transcription pathways as specific targets for low molecular weight phosphotyrosine-protein phosphatase in platelet-derived growth factor signaling

scientific article published on March 1998

The biphasic nature of hypoxia-induced directional migration of activated human hepatic stellate cells

scientific article published on 5 December 2011

The chemokine CCL21 modulates lymphocyte recruitment and fibrosis in chronic hepatitis C.

scientific article published in October 2003

The evolutionary scenario of hepatocellular carcinoma in Italy: an update.

scientific article published on 18 July 2016

The inflammasome in liver disease

scientific article published on 19 September 2016

The metabolic syndrome and chronic liver disease

scientific article published on January 2014

The mitogen-activated protein kinase ERK5 regulates the development and growth of hepatocellular carcinoma.

scientific article published on 2 September 2014

The protein kinase CK2 contributes to the malignant phenotype of cholangiocarcinoma cells

scientific article published on 22 October 2019

Therapeutic application of stem cells in gastroenterology: an up-date

scientific article

Thiazolidinediones and hepatic fibrosis: don't wait too long.

scientific article published on July 2006

Thrombin stimulates proliferation of liver fat-storing cells and expression of monocyte chemotactic protein-1: potential role in liver injury

scientific article published on 01 September 1995

Thrombocytopenia in chronic liver disease: Lessons from transplanted patients

scientific article published on 05 September 2007

Thrombopoietin stimulates migration and activates multiple signaling pathways in hepatoblastoma cells.

scientific article published on 8 September 2005

Thromboxane-receptor blockade increases water diuresis in cirrhotic patients with ascites

scientific article published on 01 September 1992

Torasemide in the treatment of patients with cirrhosis and ascites

scientific article published on 01 January 1993

Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis

scientific article published on 01 December 2020

Transforming growth factor-beta 1 regulates platelet-derived growth factor receptor beta subunit in human liver fat-storing cells

scientific article published on 01 January 1995

Transient Hepatic Parenchymal Enhancement detected at dynamic imaging: a short instruction manual for the clinician.

scientific article published on 08 December 2011

Transjugular intrahepatic portosystemic shunt (TIPS): current indications and strategies to improve the outcomes

scientific article published on 09 January 2020

Up-regulated expression of fractalkine and its receptor CX3CR1 during liver injury in humans.

scientific article published on July 2002

Upregulation of proinflammatory and proangiogenic cytokines by leptin in human hepatic stellate cells.

scientific article published in December 2005

Utility of Tumor Burden Score to Stratify Prognosis of Patients with Hepatocellular Cancer: Results of 4759 Cases from ITA.LI.CA Study Group

scientific article published on 19 January 2018

Validity criteria for the diagnosis of fatty liver by M probe-based controlled attenuation parameter

scientific article published on 12 May 2017

c-Src activates both STAT1 and STAT3 in PDGF-stimulated NIH3T3 cells

scientific article

gp120 modulates the biology of human hepatic stellate cells: a link between HIV infection and liver fibrogenesis

scientific article

n-3 polyunsaturated fatty acids worsen inflammation and fibrosis in experimental nonalcoholic steatohepatitis

scientific article published on 15 March 2014

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