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List of works by Allan D. Struthers

A comparison between B-type natriuretic peptide, global registry of acute coronary events (GRACE) score and their combination in ACS risk stratification

scientific article published on 24 March 2009

A comparison of the aldosterone-blocking agents eplerenone and spironolactone

scientific article

A critical re-appraisal of different ways of selecting ambulatory patients with suspected heart failure for echocardiography

scientific article published on 21 July 2006

A new approach to residual risk in treated hypertension--3P screening

scientific article published on 17 June 2013

A randomized, double-blind, placebo-controlled study to determine the effects of valsartan on exercise time in patients with symptomatic heart failure with preserved ejection fraction.

scientific article published on October 2009

Adherence to angiotensin-converting-enzyme inhibitors and illness beliefs in older heart failure patients

scientific article

Adverse cardiovascular effects of acute salt loading in young normotensive individuals

scientific article published on 5 May 2008

Age is not a significant risk factor for failed trial of beta-blocker therapy in older patients with chronic heart failure

scientific article

Agreement between community echocardiography and hospital echocardiography in patients suspected of having left ventricular systolic dysfunction

scientific article published on December 2005

Aldosterone and artery compliance in heart failure.

scientific article

Aldosterone blockade reduces vascular collagen turnover, improves heart rate variability and reduces early morning rise in heart rate in heart failure patients

scientific article published on July 1997

Aldosterone blunts the baroreflex response in man

scientific article published on 01 December 1998

Aldosterone: cardiovascular assault.

scientific article

Allopurinol benefits left ventricular mass and endothelial dysfunction in chronic kidney disease

scientific article

Allopurinol improves endothelial dysfunction in chronic heart failure

scientific article published in July 2002

Allopurinol treatment reduces arterial wave reflection in stroke survivors

scientific article published on January 2008

Allopurinol: novel indications in cardiovascular disease

scientific article published on 16 July 2012

Aortic valvular heart disease: Is there a place for angiotensin-converting-enzyme inhibitors?

scientific article published on January 2013

Are natriuretic peptides clinically useful as markers of heart failure?

scientific article published on 01 September 2001

Assessment of arterial stiffness, a translational medicine biomarker system for evaluation of vascular risk.

scientific article published on January 2008

Association between allopurinol and mortality in heart failure patients: a long-term follow-up study

scientific article published in September 2009

Atherosclerosis as a systemic feature of psoriasis

scientific article published on 23 July 2010

Atrial natriuretic factor improves renal function and lowers systolic blood pressure in renal allograft recipients treated with cyclosporin A

scientific article published on May 1, 1992

Atrial natriuretic peptide increases urinary albumin excretion in men with type 1 diabetes mellitus and established microalbuminuria

scientific article published in August 1998

Atrial natriuretic peptide regulates regional vascular volume and venous tone in humans.

scientific article published on 3 July 2003

B-type natriuretic Peptide is associated with both augmentation index and left ventricular mass in diabetic patients without heart failure

scientific article published on 01 December 2005

B-type natriuretic peptide as an alternative way of assessing total cardiovascular risk in patients with diabetes mellitus

scientific article

B-type natriuretic peptide can detect silent myocardial ischaemia in asymptomatic type 2 diabetes

scientific article published on 9 December 2005

B-type natriuretic peptide identifies silent myocardial ischaemia in stroke survivors

scientific article published on 10 October 2005

B-type natriuretic peptide in the diagnosis of cardiac disease in elderly day hospital patients

scientific article published in July 2002

B-type natriuretic peptide is an independent predictor of endothelial function in man.

scientific article

B-type natriuretic peptide is associated with mortality in older functionally impaired patients

scientific article published in November 2005

Biomarkers and surrogate endpoints in cardiovascular therapeutics research: under scrutiny following results of the ENHANCE Study

scientific article published in January 2008

Brain natriuretic peptide testing for angina in a rapid-access chest pain clinic

scientific article published on 27 October 2007

C-type natriuretic peptide production by the human kidney is blunted in chronic heart failure

scientific article published on 02 October 2009

Cardiopulmonary effects of endothelin-1 in man

scientific article published on 01 February 1997

Cardiovascular autonomic function in patients with hemodynamic instability at induction of capnoperitoneum: a case-control study

scientific article published on 21 April 2004

Cardiovascular consequences of laparoscopic surgery

scientific article published on 01 August 1998

Careful screening to target interventions to prevent sudden cardiac death.

scientific article

Cholecalciferol treatment to reduce blood pressure in older patients with isolated systolic hypertension: the VitDISH randomized controlled trial

scientific article published on October 2013

Circadian variation in the effects of aldosterone blockade on heart rate variability and QT dispersion in congestive heart failure

scientific article published in June 2001

Comparison of atrial natriuretic peptide B-type natriuretic peptide, and N-terminal proatrial natriuretic peptide as indicators of left ventricular systolic dysfunction

scientific article

Correlation of angiotensin converting enzyme activity and the genotypes of the I/D polymorphism in the ACE gene with preterm birth and birth weight

scientific article published on 28 August 2008

Could BNP screening of acute chest pain cases lead to safe earlier discharge of patients with non-cardiac causes? A pilot study.

scientific article published in December 2007

Day length and weather conditions profoundly affect physical activity levels in older functionally impaired people

scientific article published on 11 December 2008

Determinants of the initial effects of captopril on blood pressure, glomerular filtration rate, and natriuresis in mild-to-moderate chronic congestive heart failure secondary to coronary artery disease.

scientific article published in June 1994

Development and Validation of a Clinical Score to Identify Echocardiographic Left Ventricular Hypertrophy in Patients With Cardiovascular Disease

article

Diagnosis and management of heart failure: implications of the recent European Society of Cardiology Guidelines for the older patient

scientific article

Diagnosis of left ventricular systolic dysfunction (LVSD): development and validation of a clinical prediction rule in primary care.

scientific article published on 7 September 2007

Diagnostic value of B-type natriuretic peptide concentrations in patients with acute myocardial infarction

scientific article published in August 1996

Differential effects of some cell signalling inhibitors upon nitric oxide synthase expression and nuclear factor-kappaB activation induced by lipopolysaccharide in rat aortic smooth muscle cells

scientific article published on May 1999

Differential expression and synthesis of natriuretic peptides determines natriuretic peptide receptor expression in primary cultures of human proximal tubular cells.

scientific article

Does a prolonged QT peak identify left ventricular hypertrophy in hypertension?

scientific article published on 01 June 2003

Does dapagliflozin regress left ventricular hypertrophy in patients with type 2 diabetes? A prospective, double-blind, randomised, placebo-controlled study

scientific article published on 23 August 2017

Does the aldosterone:renin ratio predict the efficacy of spironolactone over bendroflumethiazide in hypertension? A clinical trial protocol for RENALDO (RENin-ALDOsterone) study

scientific article

Does the ratio of serum aldosterone to plasma renin activity predict the efficacy of diuretics in hypertension? Results of RENALDO.

scientific article published in January 2010

Effect of Metformin on mortality in patients with heart failure and type 2 diabetes mellitus

scientific article published on October 2010

Effect of a seated exercise program to improve physical function and health status in frail patients > or = 70 years of age with heart failure

scientific article published on 01 May 2005

Effect of atrial natriuretic factor on platelet function in whole blood ex-vivo in man.

scientific article published on January 1990

Effect of high-dose allopurinol on exercise in patients with chronic stable angina: a randomised, placebo controlled crossover trial

scientific article

Effect of pericardiocentesis on plasma levels of brain natriuretic peptide in cardiac tamponade

scientific article published in December 1992

Effect of phenylephrine with and without atropine on QT dispersion in healthy normotensive men

scientific article published on 01 January 2000

Effect of social deprivation on mortality and the duration of hospital stay after a stroke

scientific article published on 20 June 2006

Effect of spironolactone on C-reactive protein levels in patients with heart disease

scientific article published on 08 August 2006

Effect of vitamin D on blood pressure: a systematic review and meta-analysis

scientific article published in October 2009

Effectiveness of captopril in reversing renal vasoconstriction after Q-wave acute myocardial infarction

scientific article published in February 1993

Effects of adding spironolactone to an angiotensin-converting enzyme inhibitor in chronic congestive heart failure secondary to coronary artery disease

scientific article published on 01 December 1995

Effects of aldosterone and related steroids on LPS-induced increased expression of inducible NOS in rat aortic smooth muscle cells

scientific article

Effects of aldosterone on forearm vasculature in treated chronic heart failure

scientific article published in February 2005

Effects of an exercise intervention for older heart failure patients on caregiver burden and emotional distress

scientific article published on June 2006

Effects of exogenous and endogenous natriuretic peptides on forearm vascular function in chronic heart failure

scientific article published on 4 March 2004

Effects of vitamin D supplementation on markers of vascular function after myocardial infarction--a randomised controlled trial.

scientific article published on 28 March 2012

Effects of xamoterol in acute myocardial infarction: blood pressure, heart rate, arrhythmias and early clinical course

scientific article published on 01 June 1991

Efficacy and cost of an exercise program for functionally impaired older patients with heart failure: a randomized controlled trial.

scientific article published on 23 January 2012

Elevated levels of natriuretic peptides in patients with pulmonary thromboembolism

scientific article published on 01 October 2005

Enalapril reduces QTc dispersion in mild congestive heart failure secondary to coronary artery disease

scientific article published on 01 February 1997

Endogenous angiotensin II and baroreceptor dysfunction: a comparative study of losartan and enalapril in man.

scientific article published on December 1998

Evidence for myocardial synthesis of aldosterone producing myocardial fibrosis in man.

scientific article published in April 2002

Exercise capacity and brain natruiretic peptide in hypertension

scientific article published in October 2002

Exercise training as a therapy for chronic heart failure: can older people benefit?

scientific article

Family history of premature coronary heart disease and risk prediction

scientific article published on 01 March 2011

Furosemide responsiveness, non-adherence and resistance during the chronic treatment of heart failure: a longitudinal study

scientific article published in May 2004

Genetic variants predicting left ventricular hypertrophy in a diabetic population: a Go-DARTS study including meta-analysis.

scientific article published on 23 July 2013

Global array-based transcriptomics from minimal input RNA utilising an optimal RNA isolation process combined with SPIA cDNA probes

scientific article (publication date: 22 March 2011)

Gradual reactivation of vascular angiotensin I to angiotensin II conversion during chronic ACE inhibitor therapy in patients with diabetes mellitus

scientific article published on 04 August 2007

Gradual reactivation over time of vascular tissue angiotensin I to angiotensin II conversion during chronic lisinopril therapy in chronic heart failure

scientific article published in March 2002

Heart failure in frail elderly patients: diagnostic difficulties, co-morbidities, polypharmacy and treatment dilemmas

scientific article published in January 2002

High BNP levels in rheumatoid arthritis are related to inflammation but not to left ventricular abnormalities: a prospective case-control study

scientific article published on 05 January 2014

High sensitivity troponin T provides useful prognostic information in non-acute chest pain ⬇️

scientific article published on September 27, 2011

High-dose allopurinol improves endothelial function by profoundly reducing vascular oxidative stress and not by lowering uric acid

scientific article

High-dose allopurinol in patients with stable angina pectoris – Authors' reply

scientific article published in The Lancet

High-dose allopurinol reduces left ventricular mass in patients with ischemic heart disease

scientific article published on March 2013

High-potency statin and ezetimibe use and mortality in survivors of an acute myocardial infarction: a population-based study

scientific article published on 19 February 2014

How much echo left ventricular hypertrophy would be missed in diabetics by applying the Losartan Intervention For Endpoint Reduction electrocardiogram criteria to select patients for angiotensin receptor blockade?

scientific article

How to use natriuretic peptide levels for diagnosis and prognosis

scientific article published in October 1999

Human C-type natriuretic peptide: effects on the haemodynamic and endocrine responses to angiotensin II.

scientific article published in January 1995

Hypertensive left ventricular hypertrophy: a mechanistic approach to optimizing regression assessed by cardiovascular magnetic resonance

scientific article published on 01 October 2012

Hypothetical economic analysis of screening for left ventricular hypertrophy in high-risk normotensive populations

scientific article published in February 2004

Immediately Postoperative B-Type Natriuretic Peptide and Its Predictive Value

scientific article published on 04 December 2010

Impact of allopurinol use on urate concentration and cardiovascular outcome

scientific article

Impact of renin-angiotensin system blockade therapy on outcome in aortic stenosis.

scientific article published on August 2011

Improving the primary prevention of cardiovascular events by using biomarkers to identify individuals with silent heart disease

scientific article published on 22 August 2012

Increased plasma levels of brain natriuretic peptide in patients with isolated diastolic dysfunction

scientific article published in June 1994

Influence of candoxatril on plasma brain natriuretic peptide in heart failure

scientific article published in July 1991

Inhaled corticosteroid therapy reduces the early morning peak in cortisol and aldosterone

scientific article published on 01 October 1998

Insulin resistance is highly prevalent and is associated with reduced exercise tolerance in nondiabetic patients with heart failure

scientific article published in March 2009

Insulin sensitization therapy and the heart: focus on metformin and thiazolidinediones

scientific article published on 09 August 2012

Interactions between atrial natriuretic factor and the autonomic nervous system.

scientific article published on December 1991

Left ventricular hypertrophy is present in one-half of newly-diagnosed peripheral arterial disease patients

scientific article published on February 2007

Left ventricular hypertrophy: reduction of blood pressure already in the normal range further regresses left ventricular mass

scientific article published on 26 October 2009

Letter by Struthers et al Regarding Article, “Cross-Sectional Relations of Multiple Biomarkers From Distinct Biological Pathways to Brachial Artery Endothelial Function”

scientific article published on 01 September 2006

Lisinopril improves arterial function in hyperlipidaemia

scientific article published on 01 May 1999

Lisinopril improves endothelial function in chronic cigarette smokers

scientific article published in July 2001

Long-term follow-up of very old heart failure patients enrolled in a trial of exercise training

scientific article published in July 2007

Looking at non-genomic vascular effects of aldosterone

scientific article

Mechanistic insights into the therapeutic use of high-dose allopurinol in angina pectoris.

scientific article published on August 2011

Meta-analysis of B-type natriuretic peptide's ability to identify stress induced myocardial ischemia

scientific article published on 22 December 2010

Mineralocorticoid antagonism: a novel way to treat sarcopenia and physical impairment in older people?

scientific article published on December 2011

Mineralocorticoid receptor antagonists for heart failure with reduced ejection fraction: integrating evidence into clinical practice

scientific article published on 31 August 2012

Modulation of the renin-angiotensin-aldosterone system in heart failure

scientific article published on April 2014

More than skin deep: atherosclerosis as a systemic manifestation of psoriasis.

scientific article published on 04 June 2009

Myocardial fibrosis and QTc are reduced following treatment with spironolactone or amiloride in stroke survivors: a randomised placebo-controlled cross-over trial

scientific article published on 15 August 2013

Myocardial production of C-type natriuretic peptide in chronic heart failure

scientific article

N-terminal pro-brain natriuretic protein levels in takotsubo cardiomyopathy.

scientific article published on 24 August 2011

N-terminal proBNP--the most cost effective way to identify post myocardial infarction left ventriular dysfunction?

scientific article published in September 2000

Natriuretic peptides as a prognostic marker and therapeutic target in heart failure

scientific article published on 10 October 2005

Neuroendocrine changes post myocardial infarction: Effects of xamoterol

scientific article published on 01 July 1990

Neurohormonal reactivation in heart failure patients on chronic ACE inhibitor therapy: a longitudinal study

scientific article published on 01 December 1999

Nitric oxide: an important role in the maintenance of systemic and pulmonary vascular tone in man.

scientific article published on September 1998

Nonadherence with angiotensin-converting enzyme inhibitor therapy: a comparison of different ways of measuring it in patients with chronic heart failure

scientific article published on 01 December 1999

Novel blockers of the renin-angiotensin-aldosterone system in chronic heart failure

scientific article published on March 2014

Optimization of the contrast dose and injection rates in whole-body MR angiography at 3.0T

scientific article published on 01 November 2009

Oxidative stress in renal dysfunction: mechanisms, clinical sequelae and therapeutic options.

scientific article published on January 2010

Peripheral blood pressure measurement is as good as applanation tonometry at predicting ascending aortic blood pressure

scientific article published in March 2003

Plasma brain natriuretic peptide as an indicator for angiotensin-converting-enzyme inhibition after myocardial infarction

scientific article

Polymorphisms of the angiotensin converting enzyme gene in early-onset and late-onset pre-eclampsia

scientific article published on 4 January 2010

Polymorphisms of the angiotensin converting enzyme gene in relation to intrauterine growth restriction

scientific article published in September 2010

Prazosin blunts the antinatriuretic effect of circulating angiotensin II in man

scientific article published on November 1, 1992

Predictors of exercise capacity and everyday activity in older heart failure patients

scientific article published on 25 July 2005

Preoperative NT-proBNP and CRP predict perioperative major cardiovascular events in non-cardiac surgery

scientific article published in August 2010

Pulmonary hypertension predicts all-cause mortality in patients with heart failure: a retrospective cohort study

scientific article published on 16 December 2011

Pulse wave analysis and pulse wave velocity: a critical review of their strengths and weaknesses

scientific article

QT dispersion and sudden unexpected death in chronic heart failure

scientific article published in The Lancet

QT interval abnormalities are often present at diagnosis in diabetes and are better predictors of cardiac death than ankle brachial pressure index and autonomic function tests

scientific article published on January 2005

Rationalizing the heart failure trials: from theory to practice ⬇️

scientific article published on November 1, 1997

Relation of QT interval dispersion to the number of different cardiac abnormalities in diabetes mellitus

scientific article published on September 2002

Renal, hemodynamic and neurohormonal effects of atrial natriuretic factor in cardiac allograft recipients treated with cyclosporin A

scientific article published on 01 November 1993

Renin-angiotensin-aldosterone system inhibitors in heart failure.

scientific article published on 12 July 2013

Renin–angiotensin system blockers are associated with reduced mortality and heart failure hospitalization in patients paced for complete atrioventricular block

scientific article published on 15 November 2011

Reversible hypertension following coeliac disease treatment: the role of moderate hyperhomocysteinaemia and vascular endothelial dysfunction

scientific article published in June 2002

Right ventricular pacing impairs endothelial function in man

scientific article published on 22 February 2011

Sarcopenia--a potential target for Angiotensin-converting enzyme inhibition?

scientific article published on January 2006

Screening for treatable left ventricular abnormalities in diabetic patients ⬇️

scientific article published on February 1, 2003

Serial bedside B-type natriuretic peptide strongly predicts prognosis in acute coronary syndrome independent of echocardiographic abnormalities

scientific article published in July 2009

Serial changes in adiponectin and BNP in ACS patients: paradoxical associations with each other and with prognosis

scientific article published on 2 June 2009

Should hospitals have a designated consultant with a specific interest in heart failure?

scientific article published on 01 December 2003

Spironolactone for poorly controlled hypertension in type 2 diabetes: conflicting effects on blood pressure, endothelial function, glycaemic control and hormonal profiles

scientific article

Spironolactone has antiarrhythmic activity in ischaemic cardiac patients without cardiac failure

scientific article published in November 2007

Spironolactone impairs endothelial function and heart rate variability in patients with type 2 diabetes

scientific article published on 9 September 2004

Spironolactone reduces brachial pulse wave velocity and PIIINP levels in hypertensive diabetic patients.

scientific article published in May 2005

Spironolactone use and renal toxicity: population based longitudinal analysis

scientific article published on 18 May 2010

Targeting the renin–angiotensin–aldosterone system in heart failure ⬇️

scientific article published on January 15, 2013

The L-arginine:nitric oxide pathway is the major source of plasma nitrite in fasted humans

scientific article published in April 1995

The OPT-CHF (Oxypurinol Therapy for Congestive Heart Failure) trial: a question of dose.

scientific article

The accuracy of symptoms, signs and diagnostic tests in the diagnosis of left ventricular dysfunction in primary care: a diagnostic accuracy systematic review.

scientific article

The association between serum urate levels and arterial stiffness/endothelial function in stroke survivors

scientific article

The cardiovascular risk factor, left ventricular hypertrophy, is highly prevalent in stable, treated angina pectoris

scientific article published on 01 October 2007

The clinical implications of aldosterone escape in congestive heart failure.

scientific article published in August 2004

The clinical implications of diabetic heart disease

scientific article published on 01 November 1998

The clinical pharmacology of angiotensin converting enzyme inhibitors in chronic heart failure.

scientific article

The effect of angiotensin II on haemodynamic and plasma noradrenaline responses to tyramine infusion in man

scientific article published on 01 January 1991

The effect of atrial natriuretic peptide on plasma renin activity, plasma aldosterone, and urinary dopamine in man

scientific article published on 01 January 1986

The effect of different doses of vitamin D(3) on markers of vascular health in patients with type 2 diabetes: a randomised controlled trial

scientific article published on 2 July 2010

The effect of metformin on insulin resistance and exercise parameters in patients with heart failure

scientific article published on 27 June 2012

The effect of nitric oxide inhibition on the renin response to frusemide, in man

scientific article published on September 1999

The effect of vitamin D replacement on markers of vascular health in stroke patients - a randomised controlled trial

scientific article published on 30 December 2010

The effects of vitamin D supplementation on physical function and quality of life in older patients with heart failure: a randomized controlled trial

scientific article published on 26 January 2010

The electrocardiogram is an unreliable method of identifying left ventricular hypertrophy in stable, treated angina patients

scientific article published on 20 March 2008

The epidemiology of left ventricular hypertrophy in type 2 diabetes mellitus

scientific article published on 11 August 2005

The expression and secretion of atrial natriuretic factor and brain natriuretic peptide by rat proximal tubular cells

scientific article published on 01 April 2000

The functional consequence of the Glu298Asp polymorphism of the endothelial nitric oxide synthase gene in young healthy volunteers

scientific article published in January 2007

The impact of renin-angiotensin-aldosterone system blockade on heart failure outcomes and mortality in patients identified to have aortic regurgitation: a large population cohort study.

scientific article

The influence of mode of delivery and ACE genotype on serum angiotensin converting enzyme (ACE) activity in the mother and infant at term

scientific article published in October 2007

The morning surge in blood pressure and heart rate is dependent on levels of physical activity after waking

scientific article published on 01 May 2002

The potential to improve primary prevention in the future by using BNP/N-BNP as an indicator of silent 'pancardiac' target organ damage: BNP/N-BNP could become for the heart what microalbuminuria is for the kidney

scientific article published on 14 June 2007

The practical assessment of compliance with ACE-inhibitor therapy--a novel approach

scientific article published on 01 January 1997

The prevalence of treatable left ventricular systolic dysfunction in patients who present with noncardiac vascular episodes: a case-control study

scientific article published on January 2002

The prognostic significance of early and late anaemia in acute coronary syndrome

scientific article published on 30 December 2011

The prognostic value of high sensitivity troponin T 7 weeks after an acute coronary syndrome

scientific article

The role of C-type natriuretic peptide in cardiovascular medicine.

scientific article

Therapeutic development in cardiac syndrome X: a need to target the underlying pathophysiology.

scientific article published on January 2009

Time course for recovery of atrial mechanical and endocrine function post DC cardioversion for persistent atrial fibrillation

scientific article published on 01 July 2005

Urate predicts subsequent cardiac death in stroke survivors

scientific article published on May 2002

Uric acid in chronic heart failure--current pathophysiological concepts

scientific article published on 13 November 2008

Using the demand-control model of job strain to predict caregiver burden and caregiver satisfaction in the informal caregivers of heart failure patients

scientific article published on 17 April 2007

Value of natriuretic peptides in assessment of patients with possible new heart failure in primary care

scientific article published on 01 November 1997

Vitamin D improves endothelial function in patients with Type 2 diabetes mellitus and low vitamin D levels.

scientific article published on 13 February 2008

Vitamin D therapy to reduce blood pressure and left ventricular hypertrophy in resistant hypertension: randomized, controlled trial

scientific article published on 13 January 2014

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