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List of works by Maurizio Parola

4-Hydroxynonenal as a selective pro-fibrogenic stimulus for activated human hepatic stellate cells

scientific article published on January 2004

Adipokines and redox signaling: impact on fatty liver disease

scientific article published on 05 May 2011

Age-dependent changes in extracellular matrix turnover: An under evaluated issue in the approach to chronic liver diseases

scientific article published on 30 September 2015

Alteration of Na+ homeostasis as a critical step in the development of irreversible hepatocyte injury after adenosine triphosphate depletion

scientific article published on 01 April 1995

Angiogenesis and Fibrogenesis in Chronic Liver Diseases

scientific article published on 13 July 2015

Beta-catenin triggers nuclear factor kappaB-dependent up-regulation of hepatocyte inducible nitric oxide synthase

scientific article

Beta-site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stress-activated protein kinases pathways.

scientific article published on February 2005

Biochemical studies on bile duct epithelial cells isolated from rat liver

scientific article

Calcium receptors located in fibrotic septa: a new target to reduce portal pressure in liver cirrhosis

scientific article

Calcium-dependent diuretic system in preascitic liver cirrhosis

scientific article published on 24 July 2010

Celecoxib inactivates epithelial-mesenchymal transition stimulated by hypoxia and/or epidermal growth factor in colon cancer cells

scientific article

Corrigendum to “Silibinin improves hepatic and myocardial injury in mice with nonalcoholic steatohepatitis” [Dig. Liver Dis. 44 (2012) 334–342]

scholarly article published in Digestive and Liver Disease

Curcumin limits the fibrogenic evolution of experimental steatohepatitis.

scientific article

Dehydroepiandrosterone modulates nuclear factor-kappaB activation in hippocampus of diabetic rats

scientific journal article

Detection of cytochrome P4503A (CYP3A) in human hepatic stellate cells.

scientific article published on September 1997

Dissection of the biphasic nature of hypoxia-induced motogenic action in bone marrow-derived human mesenchymal stem cells.

scientific article

Dose dependent and divergent effects of superoxide anion on cell death, proliferation, and migration of activated human hepatic stellate cells

scientific article published on 24 July 2005

Dose-dependency of clonidine's effects in ascitic cirrhotic rats: comparison with α1-adrenergic agonist midodrine

scientific article published on 22 July 2015

ERK Pathway in Activated, Myofibroblast-Like, Hepatic Stellate Cells: A Critical Signaling Crossroad Sustaining Liver Fibrosis

scientific article published on 01 June 2019

Effects of carbon tetrachloride on calcium homeostasis. A critical reconsideration

scientific article published on 01 August 1989

Endocellular polyamine availability modulates epithelial-to-mesenchymal transition and unfolded protein response in MDCK cells.

scientific article

Endogenous annexin A1 is a novel protective determinant in nonalcoholic steatohepatitis in mice.

scientific article

Expression of Cox-2 in human breast cancer cells as a critical determinant of epithelial-to-mesenchymal transition and invasiveness

scientific article published on 11 December 2013

Expression of platelet-derived growth factor in newly formed cholangiocytes during experimental biliary fibrosis in rats

scientific article published on 01 July 1999

Fat-laden macrophages modulate lobular inflammation in nonalcoholic steatohepatitis (NASH).

scientific article

H2O2 and 4-hydroxynonenal mediate amyloid beta-induced neuronal apoptosis by activating JNKs and p38MAPK.

scientific article published on April 2003

Hepatic myofibroblasts and fibrogenic progression of chronic liver diseases

scientific article published on 21 April 2015

Hepatic progenitor cells express SerpinB3

scientific article

Hepatic wound repair

scientific article published on 25 September 2009

Hepatocellular metabolism of 4-hydroxy-2,3-nonenal is impaired in conditions of chronic cholestasis

scientific article published on 01 September 1995

Human hepatic stellate cells express class I alcohol dehydrogenase and aldehyde dehydrogenase but not cytochrome P4502E1.

scientific article published on January 1998

Human mesenchymal stem cells as a two-edged sword in hepatic regenerative medicine: engraftment and hepatocyte differentiation versus profibrogenic potential

scientific article published on 16 July 2007

Human-induced pluripotent stem cells as a source of hepatocyte-like cells: new kids on the block

scientific article

Hypoxia, angiogenesis and liver fibrogenesis in the progression of chronic liver diseases

scientific article published on January 2010

Induction of Procollagen Type I Gene Expression and Synthesis in Human Hepatic Stellate Cells by 4-Hydroxy-2,3-Nonenal and Other 4-Hydroxy-2,3-Alkenals Is Related to Their Molecular Structure

article

Inhibition of the high affinity Ca2(+)-ATPase activity in rat liver plasma membranes following carbon tetrachloride intoxication

scientific article published on January 1990

Interaction between 4-hydroxy-2,3-alkenals and the platelet-derived growth factor-beta receptor. Reduced tyrosine phosphorylation and downstream signaling in hepatic stellate cells

scientific article published on December 2000

Intracellular free iron and acidic pathways mediate TNF-induced death of rat hepatoma cells.

scientific article published on August 2005

Intracellular reactive oxygen species are required for directional migration of resident and bone marrow-derived hepatic pro-fibrogenic cells.

scientific article

Isolation and characterization of biliary epithelial cells from normal rat liver

scientific article published in April 1988

Lipid-induced toxicity stimulates hepatocytes to release angiogenic microparticles that require Vanin-1 for uptake by endothelial cells

scientific article

Liver AP-1 activation due to carbon tetrachloride is potentiated by 1,2-dibromoethane but is inhibited by alpha-tocopherol or gadolinium chloride

scientific article published on 01 May 1999

Liver fibrogenic cells ⬇️

scientific article published on April 1, 2011

Liver/kidney microsomal antibody type 1 targets CYP2D6 on hepatocyte plasma membrane.

scientific article

Mammalian target of rapamycin mediates the angiogenic effects of leptin in human hepatic stellate cells

scientific article published on 20 January 2011

Menadione and cumene hydroperoxide induced cytotoxicity in biliary epithelial cells isolated from rat liver

scientific article published on 01 June 1990

Mitochondrial damage and its role in causing hepatocyte injury during stimulation of lipid peroxidation by iron nitriloacetate

scientific article published in August 1992

Modulation of hepatic fibrogenesis by antioxidants.

scientific article

Multiple signaling events in amyloid beta-induced, oxidative stress-dependent neuronal apoptosis

scientific article

Myofibroblast - like cells and liver fibrogenesis: Emerging concepts in a rapidly moving scenario.

scientific article published on 07 October 2007

Myogenic Potential of Whole Bone Marrow Mesenchymal Stem Cells In Vitro and In Vivo for Usage in Urinary Incontinence ⬇️

scientific article published on September 21, 2012

Neutral endopeptidase (EC 3.4.24.11) in cirrhotic liver: a new target to treat portal hypertension?

scientific article published on 20 June 2005

Of FACT complex and oxidative stress response: a KEAP1/NRF2-dependent novel mechanism sustaining hepatocellular carcinoma progression

scientific article published on 15 October 2019

On the role of lipid peroxidation in the pathogenesis of liver damage induced by long-standing cholestasis

scientific article published on 01 January 1996

Overexpression of Bcl-2 by activated human hepatic stellate cells: resistance to apoptosis as a mechanism of progressive hepatic fibrogenesis in humans.

scientific article published on 19 January 2006

Oxidative damage and fibrogenesis

scientific article published on January 1997

Oxidative stress-related molecules and liver fibrosis

scientific article

Pathogenesis of solute-free water retention in experimental ascitic cirrhosis: is vasopressin the only culprit?

scientific article published on 30 October 2015

Phosphatidylinositol 3-kinase is required for platelet-derived growth factor's actions on hepatic stellate cells

scientific article published on 01 April 1997

Prevention of severe toxic liver injury and oxidative stress in MCP-1-deficient mice

article

Redox mechanisms in hepatic chronic wound healing and fibrogenesis

scientific article

Redox mechanisms switch on hypoxia-dependent epithelial-mesenchymal transition in cancer cells

scientific article published on 12 September 2008

Resistin as an intrahepatic cytokine: overexpression during chronic injury and induction of proinflammatory actions in hepatic stellate cells

scientific article published on December 2006

SERPINB3 induces epithelial-mesenchymal transition

scientific article

SerpinB3 Differently Up-Regulates Hypoxia Inducible Factors -1α and -2α in Hepatocellular Carcinoma: Mechanisms Revealing Novel Potential Therapeutic Targets

scientific article published on 04 December 2019

SerpinB3 and Yap Interplay Increases Myc Oncogenic Activity.

scientific article

Silibinin improves hepatic and myocardial injury in mice with nonalcoholic steatohepatitis.

scientific article

Stem and progenitor cells in liver regeneration and repair.

scientific article published on February 2011

Stem cells in liver failure

scientific article published on February 2012

Stimulation of lipid peroxidation increases the intracellular calcium content of isolated hepatocytes

scientific article published on 01 February 1991

Stimulation of lipid peroxidation or 4-hydroxynonenal treatment increases procollagen alpha 1 (I) gene expression in human liver fat-storing cells

scientific article published on 01 August 1993

Structure-activity relationships of calmodulin antagonism by triphenylethylene antiestrogens

scientific article published on 01 September 1986

The biphasic nature of hypoxia-induced directional migration of activated human hepatic stellate cells

scientific article published on 5 December 2011

The mitogen-activated protein kinase ERK5 regulates the development and growth of hepatocellular carcinoma.

scientific article published on 2 September 2014

The role of redox mechanisms in hepatic chronic wound healing and fibrogenesis

scientific article published on 6 June 2012

The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha

scientific article

Thrombopoietin stimulates migration and activates multiple signaling pathways in hepatoblastoma cells.

scientific article published on 8 September 2005

Upregulation of proinflammatory and proangiogenic cytokines by leptin in human hepatic stellate cells.

scientific article published in December 2005

Vitamin E dietary supplementation inhibits transforming growth factor beta 1 gene expression in the rat liver

scientific article published on 01 August 1992

Vitamin E dietary supplementation protects against carbon tetrachloride-induced chronic liver damage and cirrhosis

scientific article published on 01 October 1992

[Effects of alpha lipoic acid and pirfenidone on liver cells antioxidant modulation against oxidative damage]

scientific article published on 01 December 2014

n-3 polyunsaturated fatty acids worsen inflammation and fibrosis in experimental nonalcoholic steatohepatitis

scientific article published on 15 March 2014

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