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List of works by Marcello Maggiolini

17 beta-estradiol activates rapid signaling pathways involved in rat pachytene spermatocytes apoptosis through GPR30 and ER alpha.

scientific article published on 2 February 2010

17beta-estradiol, genistein, and 4-hydroxytamoxifen induce the proliferation of thyroid cancer cells through the g protein-coupled receptor GPR30.

scientific article published on 11 July 2006

17β-Estradiol activates GPER- and ESR1-dependent pathways inducing apoptosis in GC-2 cells, a mouse spermatocyte-derived cell line

scientific article published on 27 January 2012

17β-estradiol enhances α(5) integrin subunit gene expression through ERα-Sp1 interaction and reduces cell motility and invasion of ERα-positive breast cancer cells

scientific article published on 6 January 2010

A cross-talk between the androgen receptor and the epidermal growth factor receptor leads to p38MAPK-dependent activation of mTOR and cyclinD1 expression in prostate and lung cancer cells.

scientific article

A non-radioactive method for inexpensive quantitative RT-PCR

scientific article published on 01 June 1999

A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages.

scientific article

A sexually dimorphic distribution pattern of the novel estrogen receptor G-protein-coupled receptor 30 in some brain areas of the hamster

scientific article published in January 2008

Antiestrogens upregulate estrogen receptor beta expression and inhibit adrenocortical H295R cell proliferation.

scientific article published on October 2005

Aromatase overexpression enhances the stimulatory effects of adrenal androgens on MCF7 breast cancer cells

scientific article published in July 2002

Bisphenol A induces gene expression changes and proliferative effects through GPER in breast cancer cells and cancer-associated fibroblasts.

scientific article

Bone mineral density is inversely related to parathyroid hormone in adolescent girls

scientific article published on 01 March 2001

Breast cancer: from estrogen to androgen receptor

scientific article published on July 2002

Cancer associated fibroblasts: role in breast cancer and potential as therapeutic targets

scientific article published on 05 April 2020

Caveolin-1 silencing arrests the proliferation of metastatic lung cancer cells through the inhibition of STAT3 signaling

scientific article

Correction: Rigiracciolo, D.C., et al., IGF-1/IGF-1R/FAK/YAP Transduction Signaling Prompts Growth Effects in Triple-Negative Breast Cancer (TNBC) Cells. <i>Cells</i> 2020, 9, 1010

scientific article published on 06 December 2020

Cross-talk between GPER and growth factor signaling.

scientific article published on 28 March 2013

Crosstalk between Notch, HIF-1α and GPER in Breast Cancer EMT

scientific article published in 2018

Crucial role of phospholamban phosphorylation and S-nitrosylation in the negative lusitropism induced by 17β-estradiol in the male rat heart.

scientific article

Differential expression of estrogen receptors (ERalpha/ERbeta) in testis of mature and immature pigs

scientific article published in December 2004

Differential expression of steroidogenic factor-1/adrenal 4 binding protein and liver receptor homolog-1 (LRH-1)/fetoprotein transcription factor in the rat testis: LRH-1 as a potential regulator of testicular aromatase expression

scientific article published on 21 January 2004

Differential phosphorylation of c-Jun and JunD in response to the epidermal growth factor is determined by the structure of MAPK targeting sequences

scientific article published on 15 December 2003

E-cadherin mediates the aggregation of breast cancer cells induced by tamoxifen and epidermal growth factor.

scientific article

Effects of atrazine on estrogen receptor α- and G protein-coupled receptor 30-mediated signaling and proliferation in cancer cells and cancer-associated fibroblasts

scientific article

Endothelin-1 induces connective tissue growth factor expression in cardiomyocytes

scientific article

Estriol acts as a GPR30 antagonist in estrogen receptor-negative breast cancer cells.

scientific article

Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF

scientific article published on 15 January 2009

Estrogenic and antiproliferative activities of isoliquiritigenin in MCF7 breast cancer cells

scientific article published in November 2002

Evidence that bergapten, independently of its photoactivation, enhances p53 gene expression and induces apoptosis in human breast cancer cells.

scientific article

Fibronectin and type IV collagen activate ERalpha AF-1 by c-Src pathway: effect on breast cancer cell motility

scientific article published in November 2004

Follow-up study of thyroid function in polytransfused thalassemic patients

scientific article published on 01 February 1995

G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells

scientific article published on February 2007

G protein-coupled receptor 30 expression is up-regulated by EGF and TGF alpha in estrogen receptor alpha-positive cancer cells

scientific article published on 11 September 2009

G protein-coupled receptors: novel targets for drug discovery in cancer

scientific article published on January 2011

GH Secretion in Thalassemic Patients with Short Stature

scientific article published on 01 January 1995

GPCR Modulation in Breast Cancer

scientific article published in 2018

GPCRs and cancer ⬇️

scientific article published on January 23, 2012

GPER Function in Breast Cancer: An Overview

scientific article published in 2014

GPER Mediates a Feedforward FGF2/FGFR1 Paracrine Activation Coupling CAFs to Cancer Cells toward Breast Tumor Progression

scientific article published on 07 March 2019

GPER activates Notch signaling in breast cancer cells and cancer-associated fibroblasts (CAFs).

scientific article published on 22 November 2013

GPER mediates activation of HIF1α/VEGF signaling by estrogens

scientific article

GPER mediates cardiotropic effects in spontaneously hypertensive rat hearts

scientific article

GPER mediates the Egr-1 expression induced by 17β-estradiol and 4-hydroxitamoxifen in breast and endometrial cancer cells.

scientific article

GPER1 is regulated by insulin in cancer cells and cancer-associated fibroblasts

scientific article

Glycerophospholipid synthesis as a novel drug target against cancer.

scientific article

Gper and ESRs are expressed in rat round spermatids and mediate oestrogen-dependent rapid pathways modulating expression of cyclin B1 and Bax.

scientific article

HIF-1α/GPER signaling mediates the expression of VEGF induced by hypoxia in breast cancer associated fibroblasts (CAFs)

scientific article published on January 2013

IGF-1/IGF-1R/FAK/YAP Transduction Signaling Prompts Growth Effects in Triple-Negative Breast Cancer (TNBC) Cells

scientific article published on 18 April 2020

Identification of the estrogen receptor GPER in neoplastic and non-neoplastic human testes

scientific article published on 5 October 2011

Identification of two benzopyrroloxazines acting as selective GPER antagonists in breast cancer cells and cancer-associated fibroblasts

scientific article

Inhibition of cyclin D1 expression by androgen receptor in breast cancer cells--identification of a novel androgen response element

scientific article

Inhibition of cyclooxygenase-2 down-regulates aromatase activity and decreases proliferation of Leydig tumor cells

scientific article published on 13 August 2009

Insulin-like growth factor-I regulates GPER expression and function in cancer cells

scientific article

Interaction of the Anti-Proliferative GPER Inverse Agonist ERα17p with the Breast Cancer Cell Plasma Membrane: From Biophysics to Biology

scientific article published on 15 February 2020

Leptin induces, via ERK1/ERK2 signal, functional activation of estrogen receptor alpha in MCF-7 cells.

scientific article published on 25 February 2004

MIBE acts as antagonist ligand of both estrogen receptor α and GPER in breast cancer cells.

scientific article

Metformin counteracts stimulatory effects induced by insulin in primary breast cancer cells

scientific article published on 07 June 2022

Metformin inhibits androgen-induced IGF-IR up-regulation in prostate cancer cells by disrupting membrane-initiated androgen signaling

scientific article published on 17 January 2014

Multifaceted Interplay between Hormones, Growth Factors and Hypoxia in the Tumor Microenvironment

scientific article published in 2022

Multisite phosphorylation of c-Jun at threonine 91/93/95 triggers the onset of c-Jun pro-apoptotic activity in cerebellar granule neurons

scientific article

Negative charged threonine 95 of c-Jun is essential for c-Jun N-terminal kinase-dependent phosphorylation of threonine 91/93 and stress-induced c-Jun biological activity.

scientific article published on 10 August 2007

New advances on the functional cross-talk between insulin-like growth factor-I and estrogen signaling in cancer.

scientific article published on 28 March 2012

New titanocene derivatives with high antiproliferative activity against breast cancer cells

scientific article published on 3 December 2013

Niacin activates the G protein estrogen receptor (GPER)-mediated signalling.

scientific article

Non-genomic signaling by steroids

scientific article published on 21 April 2009

Novel Aspects Concerning the Functional Cross-Talk between the Insulin/IGF-I System and Estrogen Signaling in Cancer Cells

scientific article

Nuclear alternate estrogen receptor GPR30 mediates 17beta-estradiol-induced gene expression and migration in breast cancer-associated fibroblasts

scientific article

Oestrogen receptor beta is required for androgen-stimulated proliferation of LNCaP prostate cancer cells

scientific article published on June 2004

Oleuropein and hydroxytyrosol activate GPER/ GPR30-dependent pathways leading to apoptosis of ER-negative SKBR3 breast cancer cells.

scientific article

Oleuropein and hydroxytyrosol inhibit MCF-7 breast cancer cell proliferation interfering with ERK1/2 activation.

scientific article

Peroxisome proliferator-activated receptor-gamma activates p53 gene promoter binding to the nuclear factor-kappaB sequence in human MCF7 breast cancer cells

scientific article

Rhenium(IV) compounds inducing apoptosis in cancer cells.

scientific article published on 29 March 2011

Role of cyclic AMP response element-binding protein in insulin-like growth factor-i receptor up-regulation by sex steroids in prostate cancer cells

scientific article

SLC37A1 gene expression is up-regulated by epidermal growth factor in breast cancer cells.

scientific article published on 6 November 2009

Structure-activity relationships of resveratrol and derivatives in breast cancer cells.

scientific article

Synthesis, characterization and cytotoxic activity on breast cancer cells of new half-titanocene derivatives.

scientific article published on 26 March 2013

Tamoxifen through GPER upregulates aromatase expression: a novel mechanism sustaining tamoxifen-resistant breast cancer cell growth

scientific article

The FGF/FGFR System in Breast Cancer: Oncogenic Features and Therapeutic Perspectives

scientific article published on 18 October 2020

The G Protein-Coupled Estrogen Receptor (GPER) Expression Correlates with Pro-Metastatic Pathways in ER-Negative Breast Cancer: A Bioinformatics Analysis

scientific article published on 04 March 2020

The G protein-coupled receptor GPR30 mediates c-fos up-regulation by 17beta-estradiol and phytoestrogens in breast cancer cells.

scientific article

The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17beta-estradiol and hydroxytamoxifen in endometrial cancer cells

scientific article published on 20 October 2005

The Peptide ERα17p Is a GPER Inverse Agonist that Exerts Antiproliferative Effects in Breast Cancer Cells

scientific article published on 14 June 2019

The cholesterol metabolite 25-hydroxycholesterol activates estrogen receptor α-mediated signaling in cancer cells and in cardiomyocytes

scientific article

The direct proliferative stimulus of dehydroepiandrosterone on MCF7 breast cancer cells is potentiated by overexpression of aromatase

scientific article

The effect of dietary calcium intake on bone mineral density in healthy adolescent girls and young women in southern Italy

scientific article published on 01 June 1999

The estrogen receptor α is the key regulator of the bifunctional role of FoxO3a transcription factor in breast cancer motility and invasiveness

scientific article published on 17 September 2013

The food contaminants bisphenol A and 4-nonylphenol act as agonists for estrogen receptor alpha in MCF7 breast cancer cells

scientific article published on December 2003

The mutant androgen receptor T877A mediates the proliferative but not the cytotoxic dose-dependent effects of genistein and quercetin on human LNCaP prostate cancer cells

scientific article published in November 2002

The novel estrogen receptor, G protein-coupled receptor 30, mediates the proliferative effects induced by 17beta-estradiol on mouse spermatogonial GC-1 cell line.

scientific article

The nuclear localization signal is required for nuclear GPER translocation and function in breast Cancer-Associated Fibroblasts (CAFs).

scientific article published on 5 June 2013

The red wine phenolics piceatannol and myricetin act as agonists for estrogen receptor alpha in human breast cancer cells.

scientific article

The unfolding stories of GPR30, a new membrane-bound estrogen receptor.

scientific article published on 18 September 2009

Xenoestrogens and the induction of proliferative effects in breast cancer cells via direct activation of oestrogen receptor alpha.

scientific article published on February 2004

c-Jun activation is required for 4-hydroxytamoxifen-induced cell death in breast cancer cells.

scientific article

miR-338-3p Is Regulated by Estrogens through GPER in Breast Cancer Cells and Cancer-Associated Fibroblasts (CAFs)

scientific article published on 09 November 2018

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