Search filters

List of works by Claire J Cairney

A 'synthetic-sickness' screen for senescence re-engagement targets in mutant cancer backgrounds

scientific article

A gene expression signature classifying telomerase and ALT immortalization reveals an hTERT regulatory network and suggests a mesenchymal stem cell origin for ALT.

scientific article

A small molecule modulator of prion protein increases human mesenchymal stem cell lifespan, ex vivo expansion, and engraftment to bone marrow in NOD/SCID mice

scientific article published in June 2012

A systems biology approach to Down syndrome: identification of Notch/Wnt dysregulation in a model of stem cells aging.

scientific article published on 6 February 2009

Annexin A8 identifies a subpopulation of transiently quiescent c-kit positive luminal progenitor cells of the ductal mammary epithelium.

scientific article

Cancer cell senescence: a new frontier in drug development.

scientific article published on 31 January 2012

Cell-based screen for altered nuclear phenotypes reveals senescence progression in polyploid cells after Aurora kinase B inhibition

scientific article

Dynamic telomerase gene suppression via network effects of GSK3 inhibition

scientific article

Ectopically hTERT expressing adult human mesenchymal stem cells are less radiosensitive than their telomerase negative counterpart

scientific article published on 08 January 2007

Identification of a Selective G1-Phase Benzimidazolone Inhibitor by a Senescence-Targeted Virtual Screen Using Artificial Neural Networks

scientific article published on September 2015

Isolation, culture, and transfection of melanocytes

scientific article published on 03 June 2014

Mathematical model of a telomerase transcriptional regulatory network developed by cell-based screening: analysis of inhibitor effects and telomerase expression mechanisms

scientific article (publication date: February 2014)

Pathway analysis of senescence-associated miRNA targets reveals common processes to different senescence induction mechanisms

scientific article published on 12 February 2009

Scoring of senescence signalling in multiple human tumour gene expression datasets, identification of a correlation between senescence score and drug toxicity in the NCI60 panel and a pro-inflammatory signature correlating with survival [...]

scientific article

TCEAL7 inhibition of c-Myc activity in alternative lengthening of telomeres regulates hTERT expression

scientific article

Targeting the telomere and shelterin complex for cancer therapy: current views and future perspectives.

scientific article published on February 2011

The PTEN regulator DJ-1 is associated with hTERT expression in clear cell renal cell carcinoma

scientific article published in August 2009

Paulina is supported by:

About Paulina

Help